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  1. Bone alters its architecture and mass in response to the mechanical environment, and thus varying loading modalities have been examined for studying load-driven bone formation. The current study aimed to evalu...

    Authors: Ping Zhang, Min Su, Shigeo M Tanaka and Hiroki Yokota
    Citation: BMC Musculoskeletal Disorders 2006 7:73
  2. Existing studies have examined the high prevalence of LBP along with the high treatment costs of patients with low back pain (LBP). Various factors have been shown to be correlated or predictive of chronic or ...

    Authors: Debra P Ritzwoller, Laurie Crounse, Susan Shetterly and Dale Rublee
    Citation: BMC Musculoskeletal Disorders 2006 7:72
  3. The main goal of physical therapy treatment (PT) in the clinical stage following total knee arthroplasty (TKA) is to prepare patients for discharge from the hospital as soon as possible after their operation. ...

    Authors: Anton F Lenssen, Yvonne HF Crijns, Eddie MH Waltjé, Mike JA van Steyn, Ruud JT Geesink, Piet A van den Brandt and Rob A de Bie
    Citation: BMC Musculoskeletal Disorders 2006 7:71
  4. Low back pain remains a costly quality-of-life-related health problem. Microdiscectomy is often the surgical procedure of choice for a symptomatic, single-level, lumbar disc herniation in younger and middle-ag...

    Authors: David M Selkowitz, Kornelia Kulig, Elizabeth M Poppert, Sean P Flanagan, Ndidiamaka D Matthews, George J Beneck, John M Popovich Jr, Jose R Lona, Kimiko A Yamada, Wendy S Burke, Carolyn Ervin and Christopher M Powers
    Citation: BMC Musculoskeletal Disorders 2006 7:70
  5. Aluminium is considered a bone toxic metal since poisoning can lead to aluminium-induced bone disease in patients with chronic renal failure. Healthy subjects with normal renal function retain 4% of the alumin...

    Authors: Hans-Olov Hellström, Bengt Mjöberg, Hans Mallmin and Karl Michaëlsson
    Citation: BMC Musculoskeletal Disorders 2006 7:69
  6. The underlying causes of spinal manipulation hypoalgesia are largely unknown. The beneficial clinical effects were originally theorized to be due to biomechanical changes, but recent research has suggested spi...

    Authors: Steven Z George, Mark D Bishop, Joel E Bialosky, Giorgio Zeppieri Jr and Michael E Robinson
    Citation: BMC Musculoskeletal Disorders 2006 7:68
  7. The past years have seen the development of many synthetic bone replacements. To test their biocompatibility and ability for osseointegration, osseoinduction and -conduction requires their placement within bon...

    Authors: Katja MR Nuss, Joerg A Auer, Alois Boos and Brigitte von Rechenberg
    Citation: BMC Musculoskeletal Disorders 2006 7:67
  8. Neck and low back pain are common musculoskeletal complaints generating large societal costs in Western populations. In this study we evaluate the magnitude of long-term health outcomes for neck and low back p...

    Authors: Sara AC Holmberg and Anders G Thelin
    Citation: BMC Musculoskeletal Disorders 2006 7:66
  9. Pain drawings are widely used as an assessment of patients' subjective pain in low back pain patients being considered for surgery. Less work has been done on primary health care patients. Moreover, the possib...

    Authors: Marie Grunnesjö, Johan Bogefeldt, Stefan Blomberg, Heléne Delaney and Kurt Svärdsudd
    Citation: BMC Musculoskeletal Disorders 2006 7:65
  10. Plantar heel pain is one of the most common musculoskeletal disorders of the foot and ankle. Treatment of the condition is usually conservative, however the effectiveness of many treatments frequently used in ...

    Authors: Joel A Radford, Karl B Landorf, Rachelle Buchbinder and Catherine Cook
    Citation: BMC Musculoskeletal Disorders 2006 7:64
  11. In osteonecrosis the vascular supply of the bone is interrupted and the living cells die. The inorganic mineral network remains intact until ingrowing blood vessels invade the graft. Accompanying osteoclasts s...

    Authors: Jörgen Åstrand, Anna Kajsa Harding, Per Aspenberg and Magnus Tägil
    Citation: BMC Musculoskeletal Disorders 2006 7:63
  12. Transcutaneous in vivo electroporation is expected to be an effective gene-transfer method for promoting bone regeneration using the BMP-2 plasmid vector. To promote enhanced osteoinduction using this method, we ...

    Authors: Mariko Kawai, Kazuhisa Bessho, Hiroki Maruyama, Jun-ichi Miyazaki and Toshio Yamamoto
    Citation: BMC Musculoskeletal Disorders 2006 7:62
  13. Nearly 20,000 patients per year in the UK receive total knee arthroplasty (TKA). One of the problems faced by the health services of many developed countries is the length of time patients spend waiting for el...

    Authors: Ananthan D Ebinesan, Bhupinder S Sarai, Gayle Walley, Stephen Bridgman and Nicola Maffulli
    Citation: BMC Musculoskeletal Disorders 2006 7:61
  14. Active inversion and eversion ankle range of motion (ROM) is widely used to evaluate treatment effect, however the error associated with the available measurement protocols is unknown. This study aimed to esta...

    Authors: Collette Menadue, Jacqueline Raymond, Sharon L Kilbreath, Kathryn M Refshauge and Roger Adams
    Citation: BMC Musculoskeletal Disorders 2006 7:60
  15. Chronic neck pain is highly prevalent in Western societies, with about 15% of females and 10% of males suffering with it at any time. The course of untreated chronic neck pain patients in clinical trials has n...

    Authors: Howard Vernon, B Kim Humphreys and Carol Hagino
    Citation: BMC Musculoskeletal Disorders 2006 7:58
  16. Endostatin is a C-terminal fragment of collagen XVIII which is a component of basement membranes with the structural properties of both collagens and proteoglycans. Endostatin has a major role in angiogenesis ...

    Authors: Annina Sipola, Katri Nelo, Timo Hautala, Joanna Ilvesaro and Juha Tuukkanen
    Citation: BMC Musculoskeletal Disorders 2006 7:56
  17. This article describes the background and study design of the PROMO study (Prospective Research on Musculoskeletal disorders in Office workers). Few longitudinal studies have been performed to investigate the ...

    Authors: Stefan IJmker, Birgitte M Blatter, Allard J van der Beek, Willem van Mechelen and Paulien M Bongers
    Citation: BMC Musculoskeletal Disorders 2006 7:55
  18. Clinical guidelines generally portray acute low back pain as a benign and self-limiting condition. However, evidence about the clinical course of acute low back pain is contradictory and the risk of subsequent...

    Authors: Nicholas Henschke, Christopher G Maher, Kathryn M Refshauge, Robert D Herbert, Robert G Cumming, Jane Bleasel, John York, Anurina Das and James H McAuley
    Citation: BMC Musculoskeletal Disorders 2006 7:54
  19. Independent of efficacy, information on safety of surgical procedures is essential for informed choices. We seek to develop standardized methodology for describing the safety of spinal operations and apply the...

    Authors: Sohail K Mirza, Richard A Deyo, Patrick J Heagerty, Judith A Turner, Lorri A Lee and Robert Goodkin
    Citation: BMC Musculoskeletal Disorders 2006 7:53
  20. The chondro-osseous junctional region of diarthrodial joints is peculiarly complex and may be considered to consist of the deepest layer of non-calcified cartilage, the tidemark, the layer of calcified cartila...

    Authors: Tim J Lyons, Sheena F McClure, Robert W Stoddart and John McClure
    Citation: BMC Musculoskeletal Disorders 2006 7:52
  21. The rehabilitation of knee osteoarthritis often includes electrotherapeutic modalities as well as advice and exercise. One commonly used modality is pulsed electromagnetic field therapy (PEMF). PEMF uses elect...

    Authors: Christopher James McCarthy, Michael James Callaghan and Jacqueline Anne Oldham
    Citation: BMC Musculoskeletal Disorders 2006 7:51
  22. A commercially available nanocrystalline hydroxyapatite paste Ostim® has been reported in few recent studies to surpass other synthetic bone substitutes with respect to the observed clinical results. However, the...

    Authors: Franz-Xaver Huber, Orlin Belyaev, Joachim Hillmeier, Hans-Juergen Kock, Colette Huber, Peter-Juergen Meeder and Irina Berger
    Citation: BMC Musculoskeletal Disorders 2006 7:50
  23. Posterior tibialis tendon dysfunction (PTTD) is a common cause of foot pain and dysfunction in adults. Clinical observations strongly suggest that the condition is progressive. There are currently no controlle...

    Authors: Kornelia Kulig, Amy B Pomrantz, Judith M Burnfield, Stephen F Reischl, Susan Mais-Requejo, David B Thordarson and Ronald W Smith
    Citation: BMC Musculoskeletal Disorders 2006 7:49
  24. Osteoarthritis (OA) is highly prevalent and has substantial impact on quality of life as well as on healthcare costs. The general practitioner (GP) often is the first care provider for patients with this chron...

    Authors: Thomas Rosemann, Michel Wensing, Katharina Joest, Matthias Backenstrass, Cornelia Mahler and Joachim Szecsenyi
    Citation: BMC Musculoskeletal Disorders 2006 7:48
  25. Passive joint mobilisation is a technique frequently used by physiotherapists to reduce pain, improve joint movement and facilitate a return to activities after injury, but its use after ankle fracture is curr...

    Authors: C Christine Lin, Anne M Moseley, Kathryn M Refshauge, Marion Haas and Robert D Herbert
    Citation: BMC Musculoskeletal Disorders 2006 7:46
  26. Lumbar segmental rigidity (LSR) and lumbar segmental instability (LSI) are believed to be associated with low back pain (LBP), and identification of these disorders is believed to be useful for directing inter...

    Authors: J Haxby Abbott, Julie M Fritz, Brendan McCane, Barry Shultz, Peter Herbison, Brett Lyons, Georgia Stefanko and Richard M Walsh
    Citation: BMC Musculoskeletal Disorders 2006 7:45
  27. The 30-item disabilities of the arm, shoulder and hand (DASH) questionnaire is increasingly used in clinical research involving upper extremity musculoskeletal disorders. From the original DASH a shorter versi...

    Authors: Christina Gummesson, Michael M Ward and Isam Atroshi
    Citation: BMC Musculoskeletal Disorders 2006 7:44
  28. The study was aimed at determining the prevalence of secondary amyloidosis in a group of Iranian patients with Rheumatoid Arthritis (RA), and the assessment of its correlation with the clinical and laboratory ...

    Authors: G Hussein Alishiri, Ahmad Salimzadeh, Mohammad Bagher Owlia, Jafar Forghanizadeh, Roya Setarehshenas and Nasrin Shayanfar
    Citation: BMC Musculoskeletal Disorders 2006 7:43
  29. Open discectomy is the standard surgical procedure in the treatment of patients with long-lasting sciatica caused by lumbar disc herniation. Minimally invasive approaches such as microendoscopic discectomy hav...

    Authors: Mark P Arts, Wilco C Peul, Ronald Brand, Bart W Koes and Ralph TWM Thomeer
    Citation: BMC Musculoskeletal Disorders 2006 7:42
  30. Acute scaphoid fractures are common in active adults and do lead to reasonable time lost to work. One important goal of treatment is early return to work or sport. On this background, the adequate treatment of...

    Authors: Boris M Pfeiffer, Matthias Nübling, Hartmut R Siebert and Michael Schädel-Höpfner
    Citation: BMC Musculoskeletal Disorders 2006 7:41
  31. The Catechol-O-methyltransferase (COMT) gene contains a functional polymorphism, Val158Met, that has been found to influence human pain perception. In one study fibromyalgia was less likely among those with Val/V...

    Authors: Knut Hagen, Elin Pettersen, Lars Jacob Stovner, Frank Skorpen and John-Anker Zwart
    Citation: BMC Musculoskeletal Disorders 2006 7:40
  32. As the literature now stands, a bewildering number and variety of biological, psychological and social factors are, apparently, implicated in back problems. However, if and how these have a direct influence on...

    Authors: Charlotte Leboeuf-Yde, Kristian Larsen, Ingvar Ahlstrand and Ernest Volinn
    Citation: BMC Musculoskeletal Disorders 2006 7:39
  33. Self-reported knee complaints may vary with age and gender. Reference data from the adult population would help to better interpret the outcome of interventions due to knee complaints. The objectives of the pr...

    Authors: Przemyslaw T Paradowski, Stefan Bergman, Anne Sundén-Lundius, L Stefan Lohmander and Ewa M Roos
    Citation: BMC Musculoskeletal Disorders 2006 7:38
  34. In hand and spinal surgery nerve lesions are feared complications with the use of standard oscillating saws. Oral surgeons have started using a newly developed ultrasound bone scalpel when performing precise o...

    Authors: Dominik J Hoigne, Stefan Stübinger, Oliver Von Kaenel, Sonia Shamdasani and Paula Hasenboehler
    Citation: BMC Musculoskeletal Disorders 2006 7:36
  35. The maintenance of postural control is fundamental for different types of physical activity. This can be measured by having subjects stand on one leg on a force plate. Many studies assessing standing balance h...

    Authors: Gertrud Nilsson, Eva Ageberg, Charlotte Ekdahl and Magnus Eneroth
    Citation: BMC Musculoskeletal Disorders 2006 7:35
  36. Current measures of pain assess the relative contribution of pain in different body regions to the overall impact of pain. We developed a series of questions to measure the relative 'troublesomeness' of pain i...

    Authors: Suzanne Parsons, Dawn Carnes, Tamar Pincus, Nadine Foster, Alan Breen, Steven Vogel and Martin Underwood
    Citation: BMC Musculoskeletal Disorders 2006 7:34
  37. The reliability and measurement error of several impairment measures used during the clinical examination of patients with patellofemoral pain syndrome (PFPS) has not been established. The purpose was to deter...

    Authors: Sara R Piva, Kelley Fitzgerald, James J Irrgang, Scott Jones, Benjamin R Hando, David A Browder and John D Childs
    Citation: BMC Musculoskeletal Disorders 2006 7:33
  38. Autologous and allogeneic osteochondral grafts have been used to repair damaged or diseased cartilage. There are drawbacks to both of these methods, however. Another possible source for osteochondral grafting ...

    Authors: Jill S Kawalec-Carroll, Vincent J Hetherington, Douglas S Dockery, Carey Shive, Oleg S Targoni, Paul V Lehmann, Daniel Nadler and Dustin Prins
    Citation: BMC Musculoskeletal Disorders 2006 7:32
  39. Patellofemoral complaints are frequently seen in younger and active patients. Clinical strategy is usually based on decreasing provoking activities as sports and demanding knee activities during work and leisu...

    Authors: Robbart van Linschoten, Marienke van Middelkoop, Marjolein Y Berger, Edith M Heintjes, Mark A Koopmanschap, Jan AN Verhaar, Bart W Koes and Sita MA Bierma-Zeinstra
    Citation: BMC Musculoskeletal Disorders 2006 7:31
  40. Selective non-participation at baseline (due to non-response and non-consent) and loss to follow-up are important concerns for longitudinal observational research. We investigated these matters in the context ...

    Authors: George Peat, Elaine Thomas, June Handy, Laurence Wood, Krysia Dziedzic, Helen Myers, Ross Wilkie, Rachel Duncan, Elaine Hay, Jonathan Hill, Rosie Lacey and Peter Croft
    Citation: BMC Musculoskeletal Disorders 2006 7:30
  41. It has previously been shown that low back pain (LBP) often presents already in the teenage years and that previous LBP predicts future LBP. It is also well documented that there is a large degree of comorbidi...

    Authors: Lise Hestbaek, Charlotte Leboeuf-Yde and Kirsten O Kyvik
    Citation: BMC Musculoskeletal Disorders 2006 7:29
  42. The Clubfoot Assessment Protocol (CAP) is a multi dimensional instrument designed for longitudinal follow up of the clubfoot deformity during growth. Item reliability has shown to be sufficient. In this articl...

    Authors: Hanneke Andriesse, Ewa M Roos, Gunnar Hägglund and Gun-Britt Jarnlo
    Citation: BMC Musculoskeletal Disorders 2006 7:28
  43. With more than half of the population experiencing low back pain (LBP) before the age of 20, research must focus on young populations. Lifestyle-factors might be important elements of prevention, since they ar...

    Authors: Lise Hestbaek, Charlotte Leboeuf-Yde and Kirsten Ohm Kyvik
    Citation: BMC Musculoskeletal Disorders 2006 7:27
  44. Disease-specific Quality Of Life (QOL) measures are devised to assess the impact of a specific disease across a spectrum of important domains of life. The purpose of this study was to examine the cross-section...

    Authors: Helen Razmjou, Andrea Bean, Varda van Osnabrugge, Joy C MacDermid and Richard Holtby
    Citation: BMC Musculoskeletal Disorders 2006 7:26
  45. Rotator cuff tears are the most common source of shoulder pain and disability. Only poor quality studies have compared mini-open to arthroscopic repair, leaving surgeons with inadequate evidence to support opt...

    Authors: Joy C MacDermid, Richard Holtby, Helen Razmjou and Dianne Bryant
    Citation: BMC Musculoskeletal Disorders 2006 7:25
  46. Dual-energy x-ray absorptiometry (DXA) is the criterion standard to identify low bone mineral density (BMD), but access to axial DXA may be limited or cost prohibitive. We screened for low bone mass with quant...

    Authors: Nan-Ping Yang, Ian Jen, Shao-Yuan Chuang, Shui-Hu Chen and Pesus Chou
    Citation: BMC Musculoskeletal Disorders 2006 7:24

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