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  1. Research article

    The effect of zoledronic acid on type and volume of Modic changes among patients with low back pain

    Modic changes (MC) are associated with low back pain (LBP). In this study, we compared changes in size and type of MC, after a single intravenous infusion of 5 mg zoledronic acid (ZA) or placebo, among chronic...

    Katri Koivisto, Jyri Järvinen, Jaro Karppinen, Marianne Haapea, Markus Paananen, Eero Kyllönen, Osmo Tervonen and Jaakko Niinimäki

    BMC Musculoskeletal Disorders 2017 18:274

    Published on: 23 June 2017

  2. Case report

    Prosthetic joint infection caused by Granulicatella adiacens: a case series and review of literature

    Bone and joint infection involving Granulicatella adiacens is rare, and mainly involved in cases of bacteremia and infectious endocarditis. Here we report three cases of prosthetic joint infection involving G. ad...

    Fanny Quénard, Piseth Seng, Jean-Christophe Lagier, Florence Fenollar and Andreas Stein

    BMC Musculoskeletal Disorders 2017 18:276

    Published on: 23 June 2017

  3. Research article

    Restricted posture in dentistry – a kinematic analysis of orthodontists

    This study aims at identifying orthodontic activities with the highest frequency of unfavorable/awkward and static postures held over a period of more than 4 s based on kinematic analysis. Moreover, a separate...

    Daniela Ohlendorf, Christina Erbe, Imke Hauck, Jennifer Nowak, Ingo Hermanns, Dirk Ditchen, Rolf Ellegast and David A. Groneberg

    BMC Musculoskeletal Disorders 2017 18:275

    Published on: 23 June 2017

  5. Research article

    Postoperative alignment of TKA in patients with severe preoperative varus or valgus deformity: is there a difference between surgical techniques?

    There have been conflicting studies published regarding the ability of various total knee arthroplasty (TKA) techniques to correct preoperative deformity. The purpose of this study was to compare the postopera...

    Stefan Rahm, Roland S. Camenzind, Andreas Hingsammer, Christopher Lenz, David E. Bauer, Mazda Farshad and Sandro F. Fucentese

    BMC Musculoskeletal Disorders 2017 18:272

    Published on: 21 June 2017

  6. Research article

    Prevalence of arthritis according to age, sex and socioeconomic status in six low and middle income countries: analysis of data from the World Health Organization study on global AGEing and adult health (SAGE) Wave 1

    In higher income countries, social disadvantage is associated with higher arthritis prevalence; however, less is known about arthritis prevalence or determinants in low to middle income countries (LMICs). We a...

    Sharon L. Brennan-Olsen, S. Cook, M. T. Leech, S. J. Bowe, P. Kowal, N. Naidoo, I. N. Ackerman, R. S. Page, S. M. Hosking, J. A. Pasco and M. Mohebbi

    BMC Musculoskeletal Disorders 2017 18:271

    Published on: 21 June 2017

  7. Research article

    Radiologic comparison of posterior release, internal distraction, final PSO and spinal fusion with one-stage posterior vertebral column resection for multi-level severe congenital scoliosis

    To compare radiologic results of posterior release, internal distraction, and final pedicle subtraction osteotomy (PSO) and spinal fusionwith one-stage posterior vertebral column resection (PVCR) in treating m...

    Shichang Liu, Nannan Zhang, Yueming Song, Zongrang Song, Liping Zhang, Jijun Liu, En Xie, Qining Wu and Dingjun Hao

    BMC Musculoskeletal Disorders 2017 18:270

    Published on: 20 June 2017

  8. Research article

    Impact of exercise programs among helicopter pilots with transient LBP

    Flight related low back pain (LBP) among helicopter pilots is frequent and may influence flight performance. Prolonged confined sitting during flights seems to weaken lumbar trunk (LT) muscles with associated ...

    Knut Andersen, Roald Baardsen, Ingvild Dalen and Jan Petter Larsen

    BMC Musculoskeletal Disorders 2017 18:269

    Published on: 20 June 2017

  9. Research article

    Administrative Algorithms to identify Avascular necrosis of bone among patients undergoing upper or lower extremity magnetic resonance imaging: a validation study

    Studies of the epidemiology and outcomes of avascular necrosis (AVN) require accurate case-finding methods. The aim of this study was to evaluate performance characteristics of a claims-based algorithm designe...

    Medha Barbhaiya, Yan Dong, Jeffrey A. Sparks, Elena Losina, Karen H. Costenbader and Jeffrey N. Katz

    BMC Musculoskeletal Disorders 2017 18:268

    Published on: 19 June 2017

  10. Research article

    Antiresorptive effect of a cathepsin K inhibitor ONO-5334 and its relationship to BMD increase in a phase II trial for postmenopausal osteoporosis

    ONO-5334 is a cathepsin K inhibitor that induced bone mineral density (BMD) gain in a phase II study in postmenopausal osteoporosis patients. Even though the antiresorptive effect could only be monitored in th...

    Makoto Tanaka, Yoshitaka Hashimoto, Chihiro Hasegawa, Steve Deacon and Richard Eastell

    BMC Musculoskeletal Disorders 2017 18:267

    Published on: 19 June 2017

  11. Research article

    Surgical accuracy, function, and quality of life of simultaneous versus staged bilateral Total hip Arthroplasty in patients with Osteonecrosis of the femoral head

    The optimal surgical option for patients requiring bilateral hip replacement remains controversial. The purpose of this study was to compare surgical accuracy; functional outcome and health-related quality of ...

    Seung-Chan Kim, Young-Wook Lim, Woo-Lam Jo, Dong-Chul Park, Jin-Woo Lee, Won-Woo Kang and Yong-Sik Kim

    BMC Musculoskeletal Disorders 2017 18:266

    Published on: 17 June 2017

  12. Research article

    Correlations between inflammatory cytokines, muscle damage markers and acute postoperative pain following primary total knee arthroplasty

    Despite the success of total knee arthroplasty (TKA) in reducing knee pain and improving functional disability, the management of acute postoperative pain is still unsatisfactory. This study was aimed to quant...

    Hai-bo Si, Ti-min Yang, Yi Zeng, Zong-ke Zhou, Fu-xing Pei, Yan-rong Lu, Jing-qiu Cheng and Bin Shen

    BMC Musculoskeletal Disorders 2017 18:265

    Published on: 17 June 2017

  13. Research article

    Altered somatosensory profile according to quantitative sensory testing in patients with degenerative lumbar spine disorders scheduled for surgery

    Somatosensory profiling in affected and non-affected body regions can strengthen our insight regarding the underlying pain mechanisms, which can be valuable in treatment decision making and to improve outcomes...

    Yvonne Lindbäck, Hans Tropp, Paul Enthoven, Björn Gerdle, Allan Abbott and Birgitta Öberg

    BMC Musculoskeletal Disorders 2017 18:264

    Published on: 17 June 2017

  15. Research article

    Treatment of thoracolumbar burst fractures by short-segment pedicle screw fixation using a combination of two additional pedicle screws and vertebroplasty at the level of the fracture: a finite element analysis

    Traditional one-above and one-below four-screw posterior short-segment instrumentation is used for unstable thoracolumbar burst fractures. However, this method has a high rate of implant failure and early loss...

    Jen-Chung Liao, Weng-Pin Chen and Hao Wang

    BMC Musculoskeletal Disorders 2017 18:262

    Published on: 15 June 2017

  16. Research article

    Critical shoulder angle combined with age predict five shoulder pathologies: a retrospective analysis of 1000 cases

    Acromial morphology has previously been defined as a risk factor for some shoulder pathologies. Yet, study results are inconclusive and not all major shoulder diseases have been sufficiently investigated. Thus...

    Philipp R. Heuberer, Fabian Plachel, Lukas Willinger, Philipp Moroder, Brenda Laky, Leo Pauzenberger, Fritz Lomoschitz and Werner Anderl

    BMC Musculoskeletal Disorders 2017 18:259

    Published on: 15 June 2017

  17. Research article

    More preoperative flexibility implies adequate neural pliability for curve correction without prophylactic untethering in scoliosis patients with asymptomatic tethered spinal cord, a retrospective study

    Tethered spinal cord is frequently associated with scoliosis. It is still controversial whether a prophylactic untethering is necessary before correction procedure in scoliosis patients with tethered spinal co...

    Zhenhai Zhou, Hongqi Zhang, Chaofeng Guo, Honggui Yu, Longjie Wang and Qiang Guo

    BMC Musculoskeletal Disorders 2017 18:261

    Published on: 15 June 2017

  18. Research article

    Effect of low-magnitude different-frequency whole-body vibration on subchondral trabecular bone microarchitecture, cartilage degradation, bone/cartilage turnover, and joint pain in rabbits with knee osteoarthritis

    Whole-body vibration(WBV) has been suggested for the prevention of subchondral bone loss of knee osteoarthritis (OA) . This study examined the effects of different frequency of whole-body vibration on subchond...

    Wang Junbo, Liu Sijia, Chen Hongying, Liu Lei and Wang Pu

    BMC Musculoskeletal Disorders 2017 18:260

    Published on: 15 June 2017

  19. Research article

    The pathway to consultation for rheumatoid arthritis: exploring anticipated actions between the onset of symptoms and face-to-face encounter with a healthcare professional

    When people first experience symptoms of rheumatoid arthritis (RA) they often delay seeking medical attention resulting in delayed diagnosis and treatment. This research assesses behaviours people might engage...

    Gwenda Simons, Sophie Lumley, Marie Falahee, Kanta Kumar, Christian D. Mallen, Rebecca J. Stack and Karim Raza

    BMC Musculoskeletal Disorders 2017 18:258

    Published on: 14 June 2017

  20. Research article

    Progression of function and pain relief as indicators for returning to sports after arthroscopic isolated type II SLAP repair—a prospective study

    One of the currently used surgical techniques in isolated type II SLAP lesions is arthroscopic SLAP repair. Postoperatively, patients tend to suffer from a prolonged period of pain and are restricted in their ...

    Sandra Boesmueller, Thomas M. Tiefenboeck, Marcus Hofbauer, Adam Bukaty, Gerhard Oberleitner, Wolfgang Huf and Christian Fialka

    BMC Musculoskeletal Disorders 2017 18:257

    Published on: 13 June 2017

  21. Research article

    Anterior tibial curved cortex is a reliable landmark for tibial rotational alignment in total knee arthroplasty

    Rotational alignment of the tibial component is important for long-term success of total knee arthroplasty (TKA). This study aimed to compare five axes in normal and osteoarthritic (OA) knees to determine a re...

    Joong Il Kim, Jak Jang, Ki Woong Lee, Hyuk Soo Han, Sahnghoon Lee and Myung Chul Lee

    BMC Musculoskeletal Disorders 2017 18:252

    Published on: 12 June 2017

  22. Research article

    Outcomes of cement beads and cement spacers in the treatment of bone defects associated with post-traumatic osteomyelitis

    Cement spacers (Masquelet technique) have traditionally been used for the treatment of segmental bone defects. However, no reports have used cement spacers for the treatment of small/partial segmental bone def...

    Xu-sheng Qiu, Yi-xin Chen, Xiao-yang Qi, Hong-fei Shi, Jun-fei Wang and Jin Xiong

    BMC Musculoskeletal Disorders 2017 18:256

    Published on: 12 June 2017

  24. Research article

    The mitochondrial inhibitor oligomycin induces an inflammatory response in the rat knee joint

    Recent findings support a connection between mitochondrial dysfunction and activation of inflammatory pathways in articular cells. This study investigates in vivo in an acute model whether intra-articular admi...

    Carlos Vaamonde-García, Jesús Loureiro, Marta N. Valcárcel-Ares, Romina R. Riveiro-Naveira, Olalla Ramil-Gómez, Laura Hermida-Carballo, Alberto Centeno, Rosa Meijide-Failde, Francisco J. Blanco and María J. López-Armada

    BMC Musculoskeletal Disorders 2017 18:254

    Published on: 12 June 2017

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