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  1. Study protocol

    Knee pain and related health in the community study (KPIC): a cohort study protocol

    The incidence, progression and related risk factors for recent-onset knee pain (KP) remain uncertain. This study aims to examine the natural history of KP including incidence and progression and to identify po...

    G. S. Fernandes, A. Sarmanova, S. Warner, H. Harvey, K. Akin-Akinyosoye, H. Richardson, N. Frowd, L. Marshall, J. Stocks, M. Hall, A. M. Valdes, D. Walsh, W. Zhang and M. Doherty

    BMC Musculoskeletal Disorders 2017 18:404

    Published on: 21 September 2017

  2. Research article

    Treatment and outcomes of tumor-induced osteomalacia associated with phosphaturic mesenchymal tumors: retrospective review of 12 patients

    Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome characterized by severe hypophosphatemia and osteomalacia. Nonspecific symptoms make the diagnosis elusive. In addition, locating the responsi...

    Qing-yao Zuo, Hong Wang, Wei Li, Xiao-hui Niu, Yan-hong Huang, Jia Chen, Yu-hua You, Bao-yue Liu, Ai-min Cui and Wei Deng

    BMC Musculoskeletal Disorders 2017 18:403

    Published on: 21 September 2017

  3. Research article

    Development of the “Treatment beliefs in knee and hip OsteoArthritis (TOA)” questionnaire

    Use of conservative treatment modalities in osteoarthritis (OA) is suboptimal, which appears to be partly due to patients’ beliefs about treatments. The aim of this study was to develop a research instrument a...

    Ellen M. H. Selten, Johanna E. Vriezekolk, Henk J. Schers, Marc W. Nijhof, Willemijn H. van der Laan, Roelien G. van der Meulen-Dilling, Rinie Geenen and Cornelia H. M. van den Ende

    BMC Musculoskeletal Disorders 2017 18:402

    Published on: 19 September 2017

  4. Study protocol

    Dry needling in a manual physiotherapy and therapeutic exercise protocol for patients with chronic mechanical shoulder pain of unspecific origin: a protocol for a randomized control trial

    Shoulder pain of musculoskeletal origin is the main cause of upper limb pain of non-traumatic origin. Despite being one of the most common reasons for consultation, there is no established protocol for treatme...

    Emma Tejera-Falcón, Nuria del Carmen Toledo-Martel, Francisco Manuel Sosa-Medina, Fátima Santana-González, Miriam del Pino Quintana-de la Fe, Tomás Gallego-Izquierdo and Daniel Pecos-Martín

    BMC Musculoskeletal Disorders 2017 18:400

    Published on: 18 September 2017

  5. Study protocol

    Comparison of volar-flexion, ulnar-deviation and functional position cast immobilization in the non-operative treatment of distal radius fracture in elderly patients: a pragmatic randomized controlled trial study protocol

    Distal radius fractures (DRFs) are the second most common fractures, after hip fractures, seen in clinical practice. The high incidence of low-energy trauma DRFs in elderly patients raises questions about the ...

    Lauri Raittio, Antti Launonen, Teemu Hevonkorpi, Toni Luokkala, Juha Kukkonen, Aleksi Reito, Bakir Sumrein, Minna Laitinen and Ville M. Mattila

    BMC Musculoskeletal Disorders 2017 18:401

    Published on: 18 September 2017

  6. Research article

    Prevalence and predictors of persistent pelvic girdle pain 12 years postpartum

    Pelvic girdle pain (PGP) is not always a self-limiting condition. Women with more pronounced persistent PGP (PPGP) report poorer health status compared to women with less pronounced symptoms. The knowledge con...

    Cecilia Bergström, Margareta Persson, Kari-Anne Nergård and Ingrid Mogren

    BMC Musculoskeletal Disorders 2017 18:399

    Published on: 16 September 2017

  7. Research article

    Paradoxical tunnel enlargement after ACL reconstruction with hamstring autografts when using β-TCP containing interference screws for tibial aperture fixation- prospectively comparative study

    Tibial aperture fixation with a bioabsorbable interference screw is a popular fixation method in anterior cruciate ligament reconstruction (ACLR). An interference screw containing β-tricalcium phosphate (β-TCP...

    Joon Ho Wang, Eun Su Lee and Byung Hoon Lee

    BMC Musculoskeletal Disorders 2017 18:398

    Published on: 16 September 2017

  8. Research article

    Systematic review of quantitative imaging biomarkers for neck and shoulder musculoskeletal disorders

    This study systematically summarizes quantitative imaging biomarker research in non-traumatic neck and shoulder musculoskeletal disorders (MSDs). There were two research questions: 1) Are there quantitative im...

    Judith E. Gold, David M. Hallman, Fredrik Hellström, Martin Björklund, Albert G. Crenshaw, Svend Erik Mathiassen, Mary F. Barbe and Sayed Ali

    BMC Musculoskeletal Disorders 2017 18:395

    Published on: 12 September 2017

  9. Research article

    Quantitative magnetic resonance imaging (MRI) analysis of anterior talofibular ligament in lateral chronic ankle instability ankles pre- and postoperatively

    The aim of this study was to quantitatively evaluate and characterize the dimension and signal intensity of anterior talofibular ligament (ATFL) using 3.0 T MRI in the mechanical ankle instability group pre- a...

    Wei Liu, Hong Li and Yinghui Hua

    BMC Musculoskeletal Disorders 2017 18:397

    Published on: 12 September 2017

  10. Case report

    Improved clinical outcome measures of knee pain and function with concurrent resolution of subchondral Bone Marrow Edema Lesion and joint effusion in an osteoarthritic patient following Pentosan Polysulphate Sodium treatment: a case report

    At present, there are no registered products for the treatment of subchondral Bone Marrow Edema Lesion (BML) and associated knee pain. Patients who do not respond to current anti-inflammatory therapies are lef...

    Matthew J. Sampson, Margie Kabbani, Ravi Krishnan, Michael Nganga, Annika Theodoulou and Jeganath Krishnan

    BMC Musculoskeletal Disorders 2017 18:396

    Published on: 12 September 2017

  11. Research article

    Neuroimmune expression in hip osteoarthritis: a systematic review

    Neuroimmune axis is central in the physiopathology of hip osteoarthritis (OA), but its specific pathways are still unclear. This systematic review aims to assess the nervous and immune system profile of patien...

    Manuel Ribeiro da Silva, Daniela Linhares, Daniel Marques Vasconcelos, Cecilia Juliana Alves, Nuno Neves, Gilberto Costa and Meriem Lamghari

    BMC Musculoskeletal Disorders 2017 18:394

    Published on: 11 September 2017

  12. Research article

    The added value of musculoskeletal ultrasound to clinical evaluation in the treatment decision of rheumatoid arthritis outpatients: physician experience matters

    Musculoskeletal ultrasound improves the accuracy of detecting the level of disease activity (DA) in RA patients, although its impact on the final treatment decision in a real clinical setting is uncertain. The...

    C. Sifuentes-Cantú, I. Contreras-Yáñez, L. Saldarriaga, A.C. Lozada, M. Gutiérrez and V. Pascual-Ramos

    BMC Musculoskeletal Disorders 2017 18:390

    Published on: 11 September 2017

  13. Research article

    Is additional balloon Kyphoplasty safe and effective for acute thoracolumbar burst fracture?

    Burst fracture is a common thoracolumbar injury that is treated using posterior pedicle instrumentation and fusion combined with transpedicular intracorporeal grafting after reduction. In this study, we compar...

    Ping-Jui Tsai, Ming-Kai Hsieh, Kuo-Feng Fan, Lih-Huei Chen, Chia-Wei Yu, Po-Liang Lai, Chi-Chien Niu, Tsung-Ting Tsai and Wen-Jer Chen

    BMC Musculoskeletal Disorders 2017 18:393

    Published on: 11 September 2017

  14. Research article

    Plasminogen activator inhibitor-1 deficiency enhances subchondral osteopenia after induction of osteoarthritis in mice

    Subchondral osteopenia is important for the pathophysiology of osteoarthritis (OA). Although previous studies suggest that plasminogen activator inhibitor-1 (PAI-1), an inhibitor of fibrinolysis, is related to...

    Akihiro Moritake, Naoyuki Kawao, Kiyotaka Okada, Kohei Tatsumi, Masayoshi Ishida, Katsumi Okumoto, Osamu Matsuo, Masao Akagi and Hiroshi Kaji

    BMC Musculoskeletal Disorders 2017 18:392

    Published on: 11 September 2017

  15. Research article

    Damage control surgery – experiences from a level I trauma center

    There is still no evidence in literature for damage control orthopaedics (DCO), early total care (ETC) or using external fixation solely in fractures of the long bones in multi-system-trauma. The aim of this s...

    Bernhard Gasser, Thomas M. Tiefenboeck, Sandra Boesmueller, Danijel Kivaranovic, Adam Bukaty and Patrick Platzer

    BMC Musculoskeletal Disorders 2017 18:391

    Published on: 11 September 2017

  16. Research article

    Changes in ankle joint motion after Supramalleolar osteotomy: a cadaveric model

    Malalignment of the ankle joint has been found after trauma, by neurological disorders, genetic predisposition and other unidentified factors, and results in asymmetrical joint loading. For a medial open wedge...

    Hak Jun Kim, Eui Dong Yeo, Im Joo Rhyu, Soon-Hyuck Lee, Yeon Soo Lee and Young Koo Lee

    BMC Musculoskeletal Disorders 2017 18:389

    Published on: 9 September 2017

  17. Research article

    Hospital volume and the risk of revision in Oxford unicompartmental knee arthroplasty in the Nordic countries -an observational study of 14,496 cases

    High procedure volume and dedication to unicompartmental knee arthroplasty (UKA) has been suggested to improve revision rates. This study aimed to quantify the annual hospital volume effect on revision risk in...

    Mona Badawy, Anne M. Fenstad, Christoffer A. Bartz-Johannessen, Kari Indrekvam, Leif I. Havelin, Otto Robertsson, Annette W-Dahl, Antti Eskelinen, Keijo Mäkelä, Alma B. Pedersen, Henrik M. Schrøder and Ove Furnes

    BMC Musculoskeletal Disorders 2017 18:388

    Published on: 7 September 2017

  18. Research article

    Effects of hyaluronic acid combined with anti-inflammatory drugs compared with hyaluronic acid alone, in clinical trials and experiments in osteoarthritis: a systematic review and meta-analysis

    The objectives are to compare the efficacy of intra-articular hyaluronic acid (IA-HA) alone and in combination with anti-inflammatory drugs (IA-HA + AI), corticosteroids (CS) or non-steroidal anti-inflammatory...

    Thippaporn Euppayo, Veerasak Punyapornwithaya, Siriwadee Chomdej, Siriwan Ongchai and Korakot Nganvongpanit

    BMC Musculoskeletal Disorders 2017 18:387

    Published on: 6 September 2017

  19. Study protocol

    Effectiveness of a specific manual approach to the suboccipital region in patients with chronic mechanical neck pain and rotation deficit in the upper cervical spine: study protocol for a randomized controlled trial

    Mechanical neck pain is a highly prevalent problem in primary healthcare settings. Many of these patients have restricted mobility of the cervical spine. Several manual techniques have been recommended for res...

    Vanessa González Rueda, Carlos López de Celis, Martín Eusebio Barra López, Andoni Carrasco Uribarren, Sara Castillo Tomás and Cesar Hidalgo García

    BMC Musculoskeletal Disorders 2017 18:384

    Published on: 5 September 2017

  20. Research article

    Effects of dietary gelatin hydrolysates on bone mineral density in magnesium-deficient rats

    The major types of commercially available gelatin hydrolysates are prepared from mammals or fish. Dietary gelatin hydrolysates from mammals were reported to improve bone mineral density (BMD) in some animal mo...

    Teruyuki Noma, Satoshi Takasugi, Miho Shioyama, Taketo Yamaji, Hiroyuki Itou, Yoshio Suzuki, Keishoku Sakuraba and Keisuke Sawaki

    BMC Musculoskeletal Disorders 2017 18:385

    Published on: 5 September 2017

  21. Research article

    Elution kinetics of vancomycin and gentamicin from carriers and their effects on mesenchymal stem cell proliferation: an in vitro study

    Musculoskeletal infections remain a major complication in orthopedic surgery. The local delivery of antibiotics provides the high levels required to treat an infection without systemic toxicity. However, the l...

    Tomas Kucera, Lenka Ryskova, Tomas Soukup, Jana Malakova, Eva Cermakova, Pavel Mericka, Jakub Suchanek and Pavel Sponer

    BMC Musculoskeletal Disorders 2017 18:381

    Published on: 2 September 2017

  22. Research article

    Risk factors for failure of revision total hip arthroplasty using a Kerboull-type acetabular reinforcement device

    The present study aimed to identify the risk factors associated with revision total hip arthroplasty (THA) failure using a Kerboull-type (KT) plate.

    Shinya Hayashi, Takayuki Nishiyama, Shingo Hashimoto, Tomoyuki Matsumoto, Koji Takayama, Kazunari Ishida, Kotaro Nishida and Ryosuke Kuroda

    BMC Musculoskeletal Disorders 2017 18:382

    Published on: 2 September 2017

  23. Research article

    Predicting outcome in frozen shoulder (shoulder capsulitis) in presence of comorbidity as measured with subjective health complaints and neuroticism

    There is a substantive lack of knowledge about comorbidity in patients with frozen shoulder. The aim of this study was to investigate whether subjective health complaints and Neuroticism would predict treatmen...

    Satya Pal Sharma, Rolf Moe-Nilssen, Alice Kvåle and Anders Bærheim

    BMC Musculoskeletal Disorders 2017 18:380

    Published on: 2 September 2017

  24. Research article

    Silver-coated modular Megaendoprostheses in salvage revision arthroplasty after periimplant infection with extensive bone loss – a pilot study of 34 patients

    Hip and knee replacements in patients with bone defects after infection correlates with high rates of reinfection. In this vulnerable patient population, the prevention of reinfection is to be considered super...

    Dirk Zajonz, Undine Birke, Mohamed Ghanem, Torsten Prietzel, Christoph Josten, Andreas Roth and Johannes K.M. Fakler

    BMC Musculoskeletal Disorders 2017 18:383

    Published on: 2 September 2017

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