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  1. Monoiodoacetate (MIA)-induced arthritis models are used widely in osteoarthritis (OA) research to develop effective conservative treatments for hip OA, as an alternative to joint replacement surgery. In joint ...

    Authors: Satoshi Yoh, Yuya Kawarai, Shigeo Hagiwara, Sumihisa Orita, Junichi Nakamura, Shuichi Miyamoto, Takane Suzuki, Tsutomu Akazawa, Yuki Shiko, Yohei Kawasaki and Seiji Ohtori
    Citation: BMC Musculoskeletal Disorders 2022 23:494
  2. A spinal cord injury (SCI) is a devastating, life-changing event that has profoundly deleterious effects on an individual’s health and well-being. Dysregulation of neuromuscular, cardiometabolic, and endocrine...

    Authors: K. F. Reid, T. W. Storer, K. M. Pencina, R. Valderrabano, N. K. Latham, L. Wilson, C. Ghattas, R. Dixon, A. Nunes, N. Bajdek, G. Huang, S. E. Skeels, A. P. Lin, S. M. Merugumala, H. J. Liao, M. L. Bouxsein…
    Citation: BMC Musculoskeletal Disorders 2022 23:493
  3. Effective symptom control in painful knee osteoarthritis (OA) may improve patient quality of life. In a randomised crossover trial (NCT03381248), COOLIEF* cooled radiofrequency ablation (CRFA) reduced pain and...

    Authors: Mehul J. Desai, Anthony Bentley and William A. Keck
    Citation: BMC Musculoskeletal Disorders 2022 23:491
  4. Patients suffering cartilage defects of the medial compartment with underlying varus deformity do benefit from high tibial osteotomy (HTO) even in the long term. Nonetheless, kinematic and geometric changes es...

    Authors: Lisa Bode, Jan Kühle, Anna-Sophie Brenner, Viola Freigang, Helge Eberbach, Philipp Niemeyer, Norbert P. Südkamp, Hagen Schmal and Gerrit Bode
    Citation: BMC Musculoskeletal Disorders 2022 23:489
  5. Low back pain has been associated with obesity or with being overweight. However, there are no high-quality systematic reviews that have been conducted on the effect of all types of weight loss programs focuse...

    Authors: Lu Hsi Chen, Kirsten Weber, Saba Mehrabkhani, Sarmina Baskaran, Thomas Abbass and Luciana Gazzi Macedo
    Citation: BMC Musculoskeletal Disorders 2022 23:488
  6. Smartphones provide opportunities for musculoskeletal research: they are integrated in participants’ daily lives and can be used to collect patient-reported outcomes as well as sensor data from large groups of...

    Authors: Anna L. Beukenhorst, Katie L. Druce and Diederik De Cock
    Citation: BMC Musculoskeletal Disorders 2022 23:487
  7. Osteoarthritis (OA) is the most common joint disease, and is most frequently seen in the knees. However, there is no effective therapy to relieve the progression of knee OA. Metformin is a safe, well-tolerated...

    Authors: Guangfeng Ruan, Shiwen Yuan, Aiju Lou, Yingqian Mo, Yuan Qu, Dongmei Guo, Shangqi Guan, Yan Zhang, Xiaoyong Lan, Jun Luo, Yifang Mei, Hongwei Zhang, Weirong Wu, Lie Dai, Qinghong Yu, Xiaoyan Cai…
    Citation: BMC Musculoskeletal Disorders 2022 23:486
  8. Osteogenesis Imperfecta affects approximately 1 in every 10,000 people. Musculoskeletal disorders and pain are common in adults with Osteogenesis Imperfecta, but specific knowledge of the problems people have ...

    Authors: Sophie Barlow, Lucy Dove, Anju Jaggi, Richard Keen and Judith Bubbear
    Citation: BMC Musculoskeletal Disorders 2022 23:485
  9. There is no agreement about the best reconstructive option following resection of proximal humerus tumors. The purpose of this study was to compare the functional outcomes of endoprosthesis reconstruction vers...

    Authors: Walid Atef Ebeid, Sherif Eldaw, Ismail Tawfeek Badr, Mohamed Kamal Mesregah and Bahaa Zakarya Hasan
    Citation: BMC Musculoskeletal Disorders 2022 23:484
  10. Computer-assisted preoperative planning, combined with PSI has become an effective technique for treating complex limb deformities. The purpose of this study was to evaluate the efficacy and safety of the nove...

    Authors: Xin-long Ma, Jian-xiong Ma, Xing-wen Zhao, Yu-ren Du, Ying Wang, Hao-hao Bai and Bin Lu
    Citation: BMC Musculoskeletal Disorders 2022 23:483
  11. Femoral neck fractures are the worst consequence of osteoporosis (OP), and its early prevention and treatment have become a public health problem. This study aims to investigate the relationship of bone-relate...

    Authors: Ning Xia, Yun Cai, Wei Wang, Chen Bao, Yunming Li, Qingyun Xie, Wei Xu and Da Liu
    Citation: BMC Musculoskeletal Disorders 2022 23:482
  12. Fracture nonunion/delayed union seriously affects physical and mental health and quality of life. The aim of this study was to evaluate the relative efficacy of different adjuvant treatments for nonunion/delay...

    Authors: Jun Yang, Xiangmin Zhang, Wangbo Liang, Guo Chen, Yanbo Ma, Yonghua Zhou, Rong Fen and Kaichang Jiang
    Citation: BMC Musculoskeletal Disorders 2022 23:481
  13. Retrospective cohort study.

    Authors: Bo Han, Hongtao Ding, Yong Hai, Yuzeng Liu, Li Guan, Aixing Pan, Xinuo Zhang and Peng Yin
    Citation: BMC Musculoskeletal Disorders 2022 23:480
  14. Following curettage of giant cell tumor of bone (GCTB), it is common to fill the cavity with polymethylmethacrylate (PMMA) bone cement, bone allograft, or artificial bone to maintain bone strength; however, th...

    Authors: Shinji Tsukamoto, Andreas F. Mavrogenis, Manabu Akahane, Kanya Honoki, Akira Kido, Yasuhito Tanaka, Davide Maria Donati and Costantino Errani
    Citation: BMC Musculoskeletal Disorders 2022 23:477
  15. Metatarsalgia is a common foot condition. The metatarsophalangeal stabilizing taping technique described by Yu et al. has shown good clinical results as a provisional treatment in propulsive metatarsalgia. 35 The...

    Authors: Maria Ruiz-Ramos, Ángel Manuel Orejana-García, Ignacio Vives-Merino, Carmen Bravo-Llatas, José Luis Lázaro-Martínez and Raúl Juan Molines-Barroso
    Citation: BMC Musculoskeletal Disorders 2022 23:475
  16. With the Persona® knee system a novel anatomic total knee design was developed, which has no pre-coating, whereas the predecessor knee system is pre-coated with polymethylmethacrylate (PMMA). Joint registry da...

    Authors: Dominic T. Mathis, Joshua Schmidli, Felix Amsler, Johann Henckel, Harry Hothi, Alister Hart and Michael T. Hirschmann
    Citation: BMC Musculoskeletal Disorders 2022 23:474
  17. Different from arthroscopy in other joints, more perfusion is required for a better access to perform surgical procedures in hip arthroscopic operations. The significant fluid perfused may lead to complication...

    Authors: Guanying Gao, Chang Zhou, Yingfang Ao, Jianquan Wang and Yan Xu
    Citation: BMC Musculoskeletal Disorders 2022 23:473
  18. Intertrochanteric fractures are associated with high mortality rates; however, long-term data on survival and predictors remain scarce. Therefore, this study investigated risk factors associated with 3-year mo...

    Authors: Yao Lu, Qiang Huang, Yibo Xu, Cheng Ren, Liang Sun, Wenchao Dong, Ming Li, Hanzhong Xue, Zhong Li, Kun Zhang, Teng Ma and Qian Wang
    Citation: BMC Musculoskeletal Disorders 2022 23:472
  19. To determine the prevalence and characteristics of post-COVID-19 (PC) in fibromyalgia (FM) patients.

    Authors: Javier Rivera, Tamara Rodríguez, Marta Pallarés, Isabel Castrejón, Teresa González, Laura Vallejo-Slocker, Juan Molina-Collada, Fernando Montero, Anna Arias, Miguel A. Vallejo, Jose M. Alvaro-Gracia and Antonio Collado
    Citation: BMC Musculoskeletal Disorders 2022 23:471
  20. Septic arthritis of the native shoulder is traditionally diagnosed with the same strategies as knee or hip septic arthritis. However, septic arthritis of the shoulder is frequently a missed or delayed diagnosi...

    Authors: Luis M. Salazar, Jose M. Gutierrez-Naranjo, Clarissa Meza, Andrew Gabig, Aaron J. Bois, Christina I. Brady and Anil K. Dutta
    Citation: BMC Musculoskeletal Disorders 2022 23:470
  21. Osteoarthritis (OA) and vertebral fractures at the lumbar spine lead to an overestimation of bone mineral density (BMD). Recently, a new approach for osteoporosis diagnosis, defined as radiofrequency echograph...

    Authors: Carla Caffarelli, Maria Dea Tomai Pitinca, Antonella Al Refaie, Michela De Vita, Simone Catapano and Stefano Gonnelli
    Citation: BMC Musculoskeletal Disorders 2022 23:469
  22. Local infiltration analgesia (LIA) and adductor canal block (ACB) provide postoperative analgesia for total knee arthroplasty (TKA). ACB blocks the saphenous nerve and has smaller impacts on quadriceps muscle ...

    Authors: Zhen-Yu Luo, Qiu-Ping Yu, Wei-Nan Zeng, Qiang Xiao, Xi Chen, Hao-Yang Wang and Zongke Zhou
    Citation: BMC Musculoskeletal Disorders 2022 23:468
  23. Elevated total alkaline phosphatase (T-ALP) levels are usually indicative of enhanced osteoblastic activity and bone conversion status and are thus considered as a key factor needed for fresh bone mineralizati...

    Authors: Juntao Shu, Anjun Tan, Yan Li, Hong Huang and Jingjing Yang
    Citation: BMC Musculoskeletal Disorders 2022 23:467
  24. Diabetes-associated osteoporosis are partly caused by accumulation of advanced glycation endproducts (AGEs). Glucagon-like peptide-1 (GLP-1) has been shown to regulate bone turnover. Here we explore whether GL...

    Authors: Yanzhen Cheng, Peng Liu, Qianru Xiang, Jiamin Liang, Huafeng Chen, Hua Zhang and Li Yang
    Citation: BMC Musculoskeletal Disorders 2022 23:465
  25. Neuromuscular choristomas (NMCs), are extremely rare developmental lesions that, have been previously established associated with recurrent fibromatosis after surgery, leading to several operations or even amp...

    Authors: Wen Guo, Hong Wang, Tao Chen, Wei Yang, Shu-Feng Wang and Shan-Lin Chen
    Citation: BMC Musculoskeletal Disorders 2022 23:464
  26. Malalignment of the Total Ankle Replacement (TAR) has often been postulated as the main reason for the high incidence of TAR failure. As the ankle joint has a small contact area, stresses are typically high, a...

    Authors: Sanne W. G. van Hoogstraten, Joris Hermus, Arjan C. Y. Loenen, Jacobus J. Arts and Bert van Rietbergen
    Citation: BMC Musculoskeletal Disorders 2022 23:463
  27. Conservative treatment is the recommended first-line treatment for degenerative disc diseases. Traction therapy has historically been one of the most common clinical methods to address this, but the clinical e...

    Authors: Yan-Jun Che, Jiang-Bo Guo, Yue Feng Hao and Zong-Ping Luo
    Citation: BMC Musculoskeletal Disorders 2022 23:462
  28. Implant design for the correction of osteoporotic unstable intertrochanteric fractures in elderly patients is a controversial issue. Our study aims to compare the efficacy of PFNA and cementless bipolar hemiar...

    Authors: Chengkui Cai, Liying Tian, Zhihui Chen, Pengcheng Sun and Guozhu Wang
    Citation: BMC Musculoskeletal Disorders 2022 23:461
  29. There were two ways of preparing the cement spacer: intracorporeal and extracorporeal formation. This study aimed to investigate the outcomes of extracorporeal vs. intracorporeal formation of a spacer using th...

    Authors: Junhao Luo, Fanyu Bo, Jian Wang, Yongwei Wu, Yunhong Ma, Qudong Yin and Yu Liu
    Citation: BMC Musculoskeletal Disorders 2022 23:460
  30. Neck pain is a common health problem in the general population as well as in people after natural disasters. Sleep disturbances are gaining attention as risk factors for musculoskeletal pain; however, the asso...

    Authors: Yutaka Yabe, Yoshihiro Hagiwara, Takuya Sekiguchi, Yumi Sugawara, Masahiro Tsuchiya, Shinichirou Yoshida and Ichiro Tsuji
    Citation: BMC Musculoskeletal Disorders 2022 23:459
  31. The main objective of this study was to investigate the risk factors for recollapse of new vertebral compression fractures (NVCFs) after percutaneous kyphoplasty (PKP) treatment for osteoporotic vertebral comp...

    Authors: FuCheng Bian, GuangYu Bian, Li Zhao, Shuo Huang, JinHui Fang and YongSheng An
    Citation: BMC Musculoskeletal Disorders 2022 23:458
  32. Individuals with locomotive syndrome (LS) require nursing care services owing to problems with locomotion and the musculoskeletal system. Individuals with LS generally have a reduced walking speed compared wit...

    Authors: Yuki Saito, Tomoya Ishida, Yoshiaki Kataoka, Ryo Takeda, Shigeru Tadano, Teppei Suzuki, Kentaro Nakamura, Akimi Nakata, Satoshi Osuka, Satoshi Yamada, Mina Samukawa and Harukazu Tohyama
    Citation: BMC Musculoskeletal Disorders 2022 23:457
  33. The incidence and characteristics of iatrogenic comminution (IC) are unknown, and the influence of IC on fracture union is unclear. This study was aimed to investigate the (1) incidence and characteristics of ...

    Authors: Jou-Hua Wang, Hao-Chun Chuang, Wei-Ren Su, Wei-Lun Chang, Fa-Chuan Kuan, Chih-Kai Hong and Kai-Lan Hsu
    Citation: BMC Musculoskeletal Disorders 2022 23:456
  34. Based on the Digital Imaging and Communications in Medicine (DICOM) data of three-dimensional magnetic resonance imaging (3D-MRI), finite element models of the hip joints of children with developmental dysplas...

    Authors: Jiani Liu, Tianyang Gao, Jia Li, Hui Shan and Shinong Pan
    Citation: BMC Musculoskeletal Disorders 2022 23:455
  35. The temporomandibular joint (TMJ) is one of the most complex joints in the body. Temporomandibular disorders (TMD) are among the most troublesome disorders for patients, as they can cause pain, affect oral fun...

    Authors: Mustafa Manafikhi, Jawdat Ataya and Omar Heshmeh
    Citation: BMC Musculoskeletal Disorders 2022 23:454
  36. Physical therapists (PTs) are at increased risk for development of work-related upper limb disorders (WRULDs) due to the physically intensive, constant hands-on nature of the profession. The objectives of this...

    Authors: Eliza Waller, Andrea Bowens and Nicholas Washmuth
    Citation: BMC Musculoskeletal Disorders 2022 23:453
  37. An inferior pole fracture of the patella requires surgical treatment to restore the knee extension mechanism of the knee joint. Different from other types of patellar fractures, inferior pole fractures are usu...

    Authors: Ming Li, Hongfei Qi, Teng Ma, Zhong Li, Cheng Ren, Qiang Huang, Hanzhong Xue, Yao Lu, Yanling Yang and Kun Zhang
    Citation: BMC Musculoskeletal Disorders 2022 23:452
  38. Approximately 20% of people experience chronic postsurgical pain after total knee replacement. The STAR randomised controlled trial (ISCRTN92545361) evaluated the clinical- and cost-effectiveness of a new mult...

    Authors: Andrew Moore, Vikki Wylde, Julie Bruce, Nicholas Howells, Wendy Bertram, Christopher Eccleston and Rachael Gooberman-Hill
    Citation: BMC Musculoskeletal Disorders 2022 23:451
  39. Advances in magnetic resonance imaging (MRI) have made it possible to find the vertebral body bruise (VBB), which was not found in computed tomography (CT) after trauma. There has been only one study with adul...

    Authors: Young-Woo Kim, Seong-Hwan Moon, Sung Hye Koh, Ki Tae Kim, Won Yong Yoon, Jeong Hwan Lee, Seonghyeon Kim, Paul S. Sung and Moon Soo Park
    Citation: BMC Musculoskeletal Disorders 2022 23:449
  40. Hyperplasia of the hematopoietic bone marrow in the appendicular skeleton is common. In contrast, focal hematopoietic islands within the axial skeleton are a rare entity and can confuse with osteoblastic metas...

    Authors: Sophia Samira Goller, Bernd Erber, Nicola Fink, Hans Roland Dürr, Thomas Knösel, Jens Ricke and Andrea Baur-Melnyk
    Citation: BMC Musculoskeletal Disorders 2022 23:448
  41. The purpose of this study was to investigate the surgical efficacy of crossing the cervicothoracic junction during posterior cervical laminectomy and fusion for the treatment of multilevel cervical ossificatio...

    Authors: Dong-Zhao Wu, Zhen-Fang Gu, De-Jing Meng, Shu-Bing Hou, Liang Ren and Xian-Ze Sun
    Citation: BMC Musculoskeletal Disorders 2022 23:446
  42. Knee osteoarthritis (KOA) is a painful degenerative joint disease that may limit activities of daily living. This study aimed to determine the relationship between quadriceps endurance and knee joint position ...

    Authors: Mastour Saeed Alshahrani, Ravi Shankar Reddy, Faisal Asiri, Jaya Shanker Tedla, Adel Alshahrani, Praveen Kumar Kandakurti and Venkata Nagaraj Kakaraparthi
    Citation: BMC Musculoskeletal Disorders 2022 23:444
  43. The Cumberland Ankle Instability Tool (CAIT) is a self-assessment tool for people with chronic ankle instability (CAI). This tool had been translated and validated in many languages but there is no Urdu versio...

    Authors: Basma Khan, Mehwish Ikram, Syed Shakil ur Rehman and Zaib un Nisa
    Citation: BMC Musculoskeletal Disorders 2022 23:443

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