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  1. Physical activity may benefit health and reduce risk for chronic complications in normal and people with diabetes and peripheral vascular diseases. However, it is unclear whether leg muscle fatigue after weigh...

    Authors: Chi-Wen Lung, Ben-Yi Liau, Joseph A. Peters, Li He, Runnell Townsend and Yih-Kuen Jan

    Citation: BMC Musculoskeletal Disorders 2021 22:831

    Content type: Research

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  2. Tibial internal rotation following total knee arthroplasty (TKA) is important in achieving favorable postoperative clinical outcomes. Studies have reported the effect of intraoperative soft tissue balance on t...

    Authors: Kentaro Takagi, Hiroshi Inui, Shuji Taketomi, Ryota Yamagami, Kenichi Kono, Kohei Kawaguchi, Shin Sameshima, Tomofumi Kage and Sakae Tanaka

    Citation: BMC Musculoskeletal Disorders 2021 22:830

    Content type: Research

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  3. In aging, muscle stiffness is considered as one of the factors associated with the reduction of force generation capability. There have been inconsistent findings on age-related alteration in the passive stiff...

    Authors: Jingfei Xu, Siu Ngor Fu and François Hug

    Citation: BMC Musculoskeletal Disorders 2021 22:829

    Content type: Research

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  4. Adhesive capsulitis (AC) of the shoulder, also known as frozen shoulder, causes substantial pain and disability. In cases of secondary AC, the inflammation and fibrosis of the synovial joint can be triggered b...

    Authors: Sara M. Sarasua, Sarah Floyd, William C. Bridges and Stephan G. Pill

    Citation: BMC Musculoskeletal Disorders 2021 22:828

    Content type: Research

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  5. Identifying populations with poor muscle recovery after total hip arthroplasty (THA) is important for postoperative physical therapy. Preoperative muscle strength is a strong factor that determines postoperati...

    Authors: Junya Sekita, Naonobu Takahira, Genki Iwamura, Hiroyuki Watanabe, Atsushi Kusaba and Saiji Kondo

    Citation: BMC Musculoskeletal Disorders 2021 22:827

    Content type: Research

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  6. Knee osteoarthritis is a major cause of pain and disability. Pain control is poor, with most patients remaining in moderate to severe pain. This may be because central causes of pain, a common contributor to k...

    Authors: Anita E. Wluka, Donna M. Urquhart, Andrew J. Teichtahl, Sultana Monira Hussain, Andrew Forbes, Carolyn Arnold, Yuanyuan Wang and Flavia M. Cicuttini

    Citation: BMC Musculoskeletal Disorders 2021 22:826

    Content type: Study protocol

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  7. The incidence and adverse events of postoperative blood transfusion in spinal tuberculosis (TB) have attracted increasing attention. Our purpose was to develop a prediction model to evaluate blood transfusion ...

    Authors: Shengtao Dong, Wenle Li, Zhi-Ri Tang, Haosheng Wang, Hao Pei and Bo Yuan

    Citation: BMC Musculoskeletal Disorders 2021 22:825

    Content type: Research

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  8. Multidisciplinary pain management programs based on cognitive behavioral training (CBT) principles have been shown moderately effective in improving daily functioning in patients with chronic low back pain (CL...

    Authors: Miranda L. van Hooff, Johanna E. Vriezekolk, Robert Jan Kroeze, John K. O’Dowd, Jacques van Limbeek and Maarten Spruit

    Citation: BMC Musculoskeletal Disorders 2021 22:824

    Content type: Research

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  9. Anatomical variations of the attachment of medial meniscus are a common finding. However, anomalies of the posterior horn are extremely rare. Only two cases of posterior root anomaly have been described prior ...

    Authors: Pier Paolo Mariani, Michael J Battaglia and Guglielmo Torre

    Citation: BMC Musculoskeletal Disorders 2021 22:823

    Content type: Case report

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  10. Platelet-rich plasma (PRP) has a still conflicting efficacy for knee osteoarthritis (KOA) and might be a minimally invasive and safe treatment alternative. The potential benefit of only plasma (non-enriched) h...

    Authors: Murillo Dório, Rosa Maria Rodrigues Pereira, Alexandre Galeno Branco Luz, Leticia Alle Deveza, Ricardo Manoel de Oliveira and Ricardo Fuller

    Citation: BMC Musculoskeletal Disorders 2021 22:822

    Content type: Research

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  11. The Maisonneuve fracture complex (MFC) is a well-known lower leg injury. However, the optimal treatment is still not clear and there is limited data on concomitant injuries of cartilage. Therefore, the aim of ...

    Authors: Lukas Fraissler, Georg Mattiassich, Lars Brunnader and Lukas A. Holzer

    Citation: BMC Musculoskeletal Disorders 2021 22:821

    Content type: Research

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  12. Back school programs, that improve back care and spine disease prevention knowledge are recommended at the age of 4-14 years. There is Health Questionnaire on Back Care Knowledge in the literature for children...

    Authors: Brigitta Szilágyi, Péter Tardi, Borbála Magyar, Nóra Tanács-Gulyás, Fanny Romhányi, Elizabetta Vida, Alexandra Makai and Melinda Járomi

    Citation: BMC Musculoskeletal Disorders 2021 22:820

    Content type: Research

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  13. The incidence and characteristics of deep vein thrombosis (DVT) following total knee arthroplasty (TKA) without pharmacologic prophylaxis have not been fully investigated. This study aimed to determine whether...

    Authors: Junya Itou, Umito Kuwashima, Masafumi Itoh and Ken Okazaki

    Citation: BMC Musculoskeletal Disorders 2021 22:819

    Content type: Research

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  14. Fibrosis is an important factor and process of ligamentum flavum hypertrophy. The expression of phosphodiesterase family (PDE) is related to inflammation and fibrosis. This article studied the expression of PD...

    Authors: Likang Wu, Lei Xu, Yu Chen, Guohua Xu, Qunfeng Guo, Depeng Meng, Jianping Fan, Guoqiang Song and Peng Xu

    Citation: BMC Musculoskeletal Disorders 2021 22:818

    Content type: Research

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  15. Rheumatoid arthritis (RA) and ankylosing spondylitis (AS) are associated with osteoporosis. There have not been many peripheral quantitative computed tomography (QCT) studies in patients receiving biologics. W...

    Authors: Balázs Juhász, Katalin Gulyás, Ágnes Horváth, Edit Végh, Anita Pusztai, Ágnes Szentpétery, Zsófia Pethő, Nóra Bodnár, Attila Hamar, Levente Bodoki, Harjit Pal Bhattoa, Éva Szekanecz, Katalin Hodosi, Andrea Domján, Szilvia Szamosi, Csaba Horváth…

    Citation: BMC Musculoskeletal Disorders 2021 22:817

    Content type: Research

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  16. The invasiveness of different surgical procedures is variable. The purpose of this study was to investigate the value of the postoperative neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio ...

    Authors: Zhongzheng Wang, Yanwei Wang, Yuchuan Wang, Wei Chen and Yingze Zhang

    Citation: BMC Musculoskeletal Disorders 2021 22:816

    Content type: Research

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  17. Experimental validation is the gold standard for the development of FE predictive models of bone. Employing multiple loading directions could improve this process. To capture the correct directional response o...

    Authors: Morteza Amini, Andreas Reisinger, Lena Hirtler and Dieter Pahr

    Citation: BMC Musculoskeletal Disorders 2021 22:815

    Content type: Research

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  18. Congenital bladder exstrophy is a rare malformation which is often associated with pubic diastasis and hip dysplasia. We reported the case two patients who underwent total hip arthroplasty (THA) due to advance...

    Authors: Christian Goetze, Filippo Migliorini and Christian Dominik Peterlein

    Citation: BMC Musculoskeletal Disorders 2021 22:814

    Content type: Case report

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  19. Proximal femoral replacement (PFR) is a technically demanding procedure commonly performed to restore extensive, oncological or non-oncological bone defects in a severely debilitated patient collective. Depend...

    Authors: Andreas Toepfer, Veit Straßer, Andreas Ladurner, Anna-Katharina Calek, Primoz Potocnik and Ruediger von Eisenhart-Rothe

    Citation: BMC Musculoskeletal Disorders 2021 22:813

    Content type: Research

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  20. The locking plate is a useful treatment for lateral clavicle fractures, however, there are limits to the fragment size that can be fixed. The current study aimed to measure the screw angles of three locking pl...

    Authors: Shingo Abe, Kota Koizumi, Tsuyoshi Murase and Kohji Kuriyama

    Citation: BMC Musculoskeletal Disorders 2021 22:812

    Content type: Research article

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  21. This study analyzed neck pain estimates in Brazil and its states between 2000 and 2019, in view of the country’s lacking epidemiological data.

    Authors: Lucas de Melo Castro Deligne, Maria Clara Brant Rocha, Deborah Carvalho Malta, Mohsen Naghavi and Valéria Maria de Azeredo Passos

    Citation: BMC Musculoskeletal Disorders 2021 22:811

    Content type: Research

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  22. Femoral neck fracture combined with anterior dislocation of the femoral head is very rare. To our knowledge, there is no classification system yet for this rare form of injury, and the injury mechanism of femo...

    Authors: Jichao Liu, Zhengwei Li, Jie Ding, Bingzhe Huang and Chengdong Piao

    Citation: BMC Musculoskeletal Disorders 2021 22:810

    Content type: Research

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  23. The angiotensin-converting enzyme 2 (ACE2)/angiotensin 1–7 (Ang-(1–7)) axis has been shown to protect against the age-associated decline in skeletal muscle function. Here, we investigated the protective effect...

    Authors: Ying Li, Jiao Song, Yangyang Jiang, Xue Yang, Li Cao, Chun Xiao, Suli Li, Birong Dong and Xiaoli Huang

    Citation: BMC Musculoskeletal Disorders 2021 22:809

    Content type: Research

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  24. The straight leg raise test (SLR) is one of the most utilized and studied physical tests in patients with low back pain (LBP) for the detection of lumbar disc herniation (LDH), showing high sensitivity and het...

    Authors: Janne Pesonen, Michael Shacklock, Juha-Sampo Suomalainen, Lauri Karttunen, Jussi Mäki, Olavi Airaksinen and Marinko Rade

    Citation: BMC Musculoskeletal Disorders 2021 22:808

    Content type: Research

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  25. Previous research has described a neuroprotective effect of IGF-I, supporting neuronal survival, axon growth and proliferation of muscle cells. Therefore, the association between IGF-I concentration, muscle hi...

    Authors: Stefanie Jarmusch, Lisa Baber, Martin Bidlingmaier, Uta Ferrari, Fabian Hofmeister, Stefan Hintze, Stefan Mehaffey, Peter Meinke, Carl Neuerburg, Benedikt Schoser, Fabiana Tanganelli and Michael Drey

    Citation: BMC Musculoskeletal Disorders 2021 22:807

    Content type: Research article

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  26. Performing postoperative laboratory tests following joint arthroplasty is a regular practice. However, the role of routine postoperative laboratory tests in primary hip arthroplasty is currently in doubt. This...

    Authors: Teng-Feng Zhuang, Song-Wei Huan, Si-Min Luo, Guo-Rong She, Wen-Rui Wu, Jun-Yuan Chen, Ning Liu and Zhen-Gang Zha

    Citation: BMC Musculoskeletal Disorders 2021 22:806

    Content type: Research article

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  27. The impact of intravertebral cleft (IVC) on cement leakage in percutaneous vertebroplasty (PVP) for osteoporotic vertebral compression fractures (OVCFs) has been discussed. However, the results were conflictin...

    Authors: Benqiang Tang, Songjie Xu, Xueming Chen, Libin Cui, Yanhui Wang, Xin Yan and Yadong Liu

    Citation: BMC Musculoskeletal Disorders 2021 22:805

    Content type: Research

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  28. There are no ideal plates or approaches for anatomical restoration and rigid fixation of posterolateral tibial plateau fractures. This study aimed to evaluate the short-term preliminary outcomes of our novel a...

    Authors: Pan Cai, Mingyuan Yuan, Houlin Ji, Xu Cui, Chao Shen, Xiaoxiao Zhou and Yang Yang

    Citation: BMC Musculoskeletal Disorders 2021 22:804

    Content type: Research

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  29. The purpose of this study was to determine the differences in clinical outcomes, if any, between intraoperative acute correction and postoperative gradual correction for tibial shaft fractures with multiplanar...

    Authors: Yanshi Liu, Feiyu Cai, Kai Liu, Xingpeng Zhang, Hong Li, Xuefei Fu, Tao Zhang and Aihemaitijiang Yusufu

    Citation: BMC Musculoskeletal Disorders 2021 22:803

    Content type: Research

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  30. Minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) and oblique lateral interbody fusion (OLIF) are widely used in the treatment of lumbar degenerative diseases. In the present study, a meta-a...

    Authors: Qing-Yi Zhang, Jie Tan, Kai Huang and Hui-Qi Xie

    Citation: BMC Musculoskeletal Disorders 2021 22:802

    Content type: Research

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  31. Diagnosing Kashin-Beck disease (KBD) involves damages to multiple joints and carries variable clinical symptoms, posing great challenge to the diagnosis of KBD for clinical practitioners. However, it is still ...

    Authors: Yanan Zhang, Xiaoli Wei, Chunxia Cao, Fangfang Yu, Wenrong Li, Guanghui Zhao, Haiyan Wei, Feng’e Zhang, Peilin Meng, Shiquan Sun, Mikko Juhani Lammi and Xiong Guo

    Citation: BMC Musculoskeletal Disorders 2021 22:801

    Content type: Research

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  32. The microbiology and the susceptibility patterns of infected total knee arthroplasties (TKAs) vary depending on demographic, local antimicrobial stewardship, and surgical factors. We wanted to compare the rece...

    Authors: Sujeesh Sebastian, Erdem Aras Sezgin, Justinas Stučinskas, Šarūnas Tarasevičius, Yang Liu, Deepak Bhushan Raina, Magnus Tägil, Lars Lidgren and Annette W-Dahl

    Citation: BMC Musculoskeletal Disorders 2021 22:800

    Content type: Research

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  33. This study aims primarily to investigate the outcome following surgical management of pertrochanteric fractures of patients over 90 years compared to the outcome of a control group below 90 years under special...

    Authors: Mohamed Ghanem, Jonas Garthmann, Anja Redecker, Annette Brigitte Ahrberg-Spiegl, Johannes Karl Maria Fakler and Ulrich Josef Albert Spiegl

    Citation: BMC Musculoskeletal Disorders 2021 22:799

    Content type: Research

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  34. We assessed predictive factors of patients with fractures of the lower extremities caused by trauma. We examined which factors are associated with an increased risk of failure. Furthermore, the predictive fact...

    Authors: Barbara Prediger, Thorsten Tjardes, Christian Probst, Anahieta Heu-Parvaresch, Angelina Glatt, Dominique Rodil dos Anjos, Bertil Bouillon and Tim Mathes

    Citation: BMC Musculoskeletal Disorders 2021 22:798

    Content type: Research

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  35. Osteoarthritis (OA) is the most prevalent form of joint disease and commonly affects the hip. Hip OA is associated with a high socioeconomic burden. Intra-articular hyaluronic acid (HA) injection may be of ben...

    Authors: David M. Long and Jane Fitzpatrick

    Citation: BMC Musculoskeletal Disorders 2021 22:797

    Content type: Research

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  36. The aim of this study was to assess the occurrence of self-reported musculoskeletal disorders (MSD) among Polish territorial army soldiers during the COVID-19 pandemic and to investigate whether there was a re...

    Authors: Małgorzata Grabara and Ewa Sadowska-Krępa

    Citation: BMC Musculoskeletal Disorders 2021 22:796

    Content type: Research

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  37. Spinopelvic dissociation is a transverse sacral fracture in conjunction with a vertical fracture of the sacrum on both sides, which causes the dissociation of the upper sacrum and spine from the pelvis. The mo...

    Authors: Giedrius Petryla, Rokas Bobina, Valentinas Uvarovas, Jaunius Kurtinaitis, Tomas Sveikata, Sigitas Ryliškis, Giedrius Kvederas and Igoris Šatkauskas

    Citation: BMC Musculoskeletal Disorders 2021 22:795

    Content type: Research

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  38. In scoliosis corrective surgery, total blood loss is composed of visible blood loss, including intraoperative haemorrhage and drainage, and hidden blood loss in which blood extravasates into the tissues and ac...

    Authors: Lipeng Wang, Jiangli Liu, Xiaoxiao Song, Muhui Luo and Yongquan Chen

    Citation: BMC Musculoskeletal Disorders 2021 22:794

    Content type: Research

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  39. Percutaneous endoscopic lumbar discectomy (PELD) is a promising minimally invasive treatment for lumbar disc herniation (LDH). Postoperative rehabilitation can improve patient outcomes. Not only rehabilitation...

    Authors: Zhen Lyu, Jinzhu Bai, Shizheng Chen, Jiesheng Liu and Wenlong Yu

    Citation: BMC Musculoskeletal Disorders 2021 22:793

    Content type: Research

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  40. Persistent monoarthritis in otherwise well-controlled rheumatoid arthritis presents a therapeutic challenge. Intra-articular (IA) steroids are a mainstay of treatment, though some have queried whether IA disea...

    Authors: Megan M. Sullivan, Michael M. Pham, Lisa A. Marks and Fawad Aslam

    Citation: BMC Musculoskeletal Disorders 2021 22:792

    Content type: Research

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  41. There are different procedures for both, the diagnosis and the therapy of a periprosthetic joint infection (PJI), however, national or international guidelines for a standardised treatment regime are still lac...

    Authors: Katrin Osmanski-Zenk, Annett Klinder, Christina Rimke, Dieter C. Wirtz, Christoph H. Lohmann, Holger Haas, Bernd Kladny and Wolfram Mittelmeier

    Citation: BMC Musculoskeletal Disorders 2021 22:791

    Content type: Research

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  42. The relevance of local twitch response (LTR) during dry needling technique (DNT) is controversial, and it is questioned whether LTR is necessary for successful outcomes. Furthermore, because the LTR during the...

    Authors: Carlos Cruz-Montecinos, Mauricio Cerda, Pablo Becerra, Claudio Tapia, Rodrigo Núñez-Cortés, Rodrigo Latorre-García, Sandro R. Freitas and Antonio Cuesta-Vargas

    Citation: BMC Musculoskeletal Disorders 2021 22:790

    Content type: Research

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  43. Ankylosing spondylitis (AS) is an autoimmune rheumatic disease. Few candidate gene associations have been reported for AS and the current understanding of its pathogenesis remains still poor. Thus, the exact m...

    Authors: Arezou Lari, Hamid Gholami Pourbadie, Ali Sharifi-Zarchi, Maryam Akhtari, Leila Nejatbakhsh Samimi, Ahmadreza Jamshidi and Mahdi Mahmoudi

    Citation: BMC Musculoskeletal Disorders 2021 22:789

    Content type: Research

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  44. Congenital scoliosis caused by failure of multiply vertebral segmentation with concave fused rib or unsegmented bar combined with contralateralhemivertebra is usually rigid and produces enormous asymmetric gro...

    Authors: Sheng Zhao, Xuhong Xue, Kai Li, Feng Miao and Bin Zhao

    Citation: BMC Musculoskeletal Disorders 2021 22:788

    Content type: Research

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  45. Venous thromboembolism (VTE) is a potentially fatal complication after arthroplasty. Numerous prophylactic strategies and studies to reduce VTEs have focused on the duration of the hospital stay and on few ext...

    Authors: Kai Tong, Hankun Liu, Jun Qin, Zhengqi Pan, Yangfan Shangguan, Hao Xiao, Hua Wang, Liaobin Chen and Yang Tan

    Citation: BMC Musculoskeletal Disorders 2021 22:787

    Content type: Research

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  46. Patellofemoral overstuffing after total knee arthroplasty (TKA) can cause limited range of motion and anterior knee pain. This study compared anterior prominence of femoral components among different prothesis...

    Authors: Junya Itou, Umito Kuwashima, Masafumi Itoh and Ken Okazaki

    Citation: BMC Musculoskeletal Disorders 2021 22:784

    Content type: Research

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  47. Biomechanical studies have demonstrated that uncovertebral joint contributes to segment mobility and stability to a certain extent. Simultaneously, osteophytes arising from the uncinate process are a common ca...

    Authors: Haimiti Abudouaini, Tingkui Wu, Hao Liu, Beiyu Wang, Hua Chen, Chengyi Huang, Ying Hong and Yang Meng

    Citation: BMC Musculoskeletal Disorders 2021 22:777

    Content type: Research

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  48. Management of severely angulated Rockwood and Wilkins’ type C (RW-C) thumb metacarpal base fractures in children is challenging. We report experiences of percutaneous leverage reduction and dual antegrade cros...

    Authors: Fei Qiao, Dehai Qu, Lei Cheng and Fei Jiang

    Citation: BMC Musculoskeletal Disorders 2021 22:775

    Content type: Research article

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  49. Video consultations have proven to be an efficient source of support for patient-doctor interactions and have become increasingly used in orthopedics, especially during the COVID-19 pandemic. This study analyz...

    Authors: K Estel, G Weber, F Fellmer, L Richter, S Tsitsilonis, C Willy and DA Back

    Citation: BMC Musculoskeletal Disorders 2021 22:774

    Content type: Research

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