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  1. Osteoporosis is a common metabolic bone disease that is characterized by low bone mass. However, limited efforts have been made to explore the functional relevance of the blood proteome to bone mineral density...

    Authors: Jiawen Xu, Shaoyun Zhang, Haibo Si, Yi Zeng, Yuangang Wu, Yuan Liu, Mingyang Li, Limin Wu and Bin Shen
    Citation: BMC Musculoskeletal Disorders 2022 23:530
  2. Vertebral compression fractures caused by osteoporosis are common in elderly patients and are often encountered by clinical physicians. Percutaneous balloon kyphoplasty (PKP) is widely accepted as a minimally ...

    Authors: Yi-Hsuan Lee, Po-Quang Chen and Chung-Ting Wu
    Citation: BMC Musculoskeletal Disorders 2022 23:529
  3. In primary total knee arthroplasty (TKA), tibial bone defects ≥ 10 mm in depth often become uncontained defects, a condition most surgeons find challenging to treat. Although the allogenous bone graft is a use...

    Authors: Dai Iwase, Yukie Metoki, Yasuaki Kusumoto, Jun Aikawa, Kensuke Fukushima, Shotaro Takano, Manabu Mukai, Kentaro Uchida, Gen Inoue and Masashi Takaso
    Citation: BMC Musculoskeletal Disorders 2022 23:528
  4. Most ergonomics studies on office workstations evaluate the effects of an intervention only by subjective measures such as musculoskeletal pain and discomfort. Limited evidence has been provided regarding risk...

    Authors: Fernanda Cabegi de Barros, Cristiane Shinohara Moriguchi, Thaís Cristina Chaves, David M. Andrews, Michael Sonne and Tatiana de Oliveira Sato
    Citation: BMC Musculoskeletal Disorders 2022 23:526
  5. The humerus fracture is one of the most commonly occurring fractures. In this research, we attempted to evaluate and compare the extent of malrotation and biomechanical environment after surgical treatment of ...

    Authors: Cheng Wang, Xiao-yuan Ma, Lin-tao Lu, Zheng Guo and Guo-feng Dai
    Citation: BMC Musculoskeletal Disorders 2022 23:525
  6. To compare potential of ultrashort time-to-echo (UTE) T2* mapping and T2* values from T2*-weighted imaging for assessing lumbar intervertebral disc degeneration (IVDD),with Pfirrmann grading as a reference sta...

    Authors: Li-Lan Wu, Li-Heng Liu, Sheng-Xiang Rao, Pu-Yeh Wu and Jian-Jun Zhou
    Citation: BMC Musculoskeletal Disorders 2022 23:524
  7. Modern treatment options of distal humerus fractures of active elderly patients are osteosynthesis and total elbow arthroplasty. The evidence of outcomes of ORIF after AO/OTA C-type fractures mostly predates t...

    Authors: Kaarlo V. Kervinen, Mikko T. Salmela and Tuomas A. Lähdeoja
    Citation: BMC Musculoskeletal Disorders 2022 23:523
  8. Uniportal full endoscopic posterolateral transforaminal lumbar interbody fusion (Endo-TLIF) with percutaneous pedicle screw fixation is a promising, minimally invasive method for the treatment of lumbar spondy...

    Authors: De-rong Xu, Liang-rui Luan, Xue-xiao Ma, Zhi-chao Cong and Chuan-li Zhou
    Citation: BMC Musculoskeletal Disorders 2022 23:522
  9. The application of double plating in olecranon fractures is becoming increasingly widespread. There is no research comparing this technique with traditional tension band wiring (TBW) and the single plate techn...

    Authors: Hongfei Qi, Zhong Li, Yao Lu, Teng Ma, Shuai Ji, Bing Du, Ming Li, Qiang Huang, Kun Zhang and Yanling Yang
    Citation: BMC Musculoskeletal Disorders 2022 23:521
  10. Although serum C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), plasma fibrinogen and neutrophil–lymphocyte ratio (NLR) are promising biomarkers for screening PJI in patients undergoing revision...

    Authors: Hong Xu, Li Liu, Jinwei Xie, Qiang Huang, Yahao Lai and Zongke Zhou
    Citation: BMC Musculoskeletal Disorders 2022 23:520
  11. Fibrodysplasia Ossificans Progressiva (FOP) is a genetic, progressive and devastating disease characterized by severe heterotopic ossification (HO), loss of mobility and early death. There are no FDA approved ...

    Authors: Bernard J. Smilde, Clemens Stockklausner, Richard Keen, Andrew Whittaker, Alex N. Bullock, Annette von Delft, Natasja M. van Schoor, Paul B. Yu and E. Marelise W. Eekhoff
    Citation: BMC Musculoskeletal Disorders 2022 23:519
  12. Authors: Janne Pesonen, Michael Shacklock, Juha-Sampo Suomalainen, Lauri Karttunen, Jussi Mäki, Olavi Airaksinen and Marinko Rade
    Citation: BMC Musculoskeletal Disorders 2022 23:518

    The original article was published in BMC Musculoskeletal Disorders 2021 22:808

  13. Articular surface size is traditionally considered to be a relatively stable trait throughout adulthood. Increased joint size reduces bone and cartilage tissue strains. Although physical activity (PA) has a cl...

    Authors: Juho-Antti Junno, Asla Keisu, Maisa Niemelä, Marella Modarress Julin, Raija Korpelainen, Timo Jämsä, Jaakko Niinimäki, Petri Lehenkari and Petteri Oura
    Citation: BMC Musculoskeletal Disorders 2022 23:517
  14. Persistent pain and disability in whiplash-associated disorders (WAD) grades II and III are common. In two randomized controlled trials (RCTs) of neck-specific exercises (NSE), we have seen promising results i...

    Authors: Gunnel Peterson, Siw Carlfjord, Emma Nilsing Strid, Sofia Ask, Margaretha Jönsson and Anneli Peolsson
    Citation: BMC Musculoskeletal Disorders 2022 23:516
  15. hand-arm vibration is one of the typical annoying physical factors. Hand-arm vibration syndrome (HAVS) is a disorder caused by vibrating working tools which vibrate hands beyond the threshold. Long-term HAVS m...

    Authors: Hamid Saeidnia, Reza Esmaeili, Mohammad Babamiri, Farideh Pourtaghi, Soheil Hassanipour and Gholamhossein Pourtaghi
    Citation: BMC Musculoskeletal Disorders 2022 23:515
  16. Cancer-induced bone pain (CIBP) is a kind of pain with complex pathophysiology. Proteinase-activated receptor 2 (PAR-2) is involved in CIBP. This study explored the effects of PAR-2 on CIBP rats.

    Authors: Yiting Tang, Yupeng Chen, Mingzhu Yang, Qiuhui Zheng, Yaoyuan Li and Yanju Bao
    Citation: BMC Musculoskeletal Disorders 2022 23:514
  17. PMMA bone cement leads to the development of local thrombi. Our study found that ES-PMMA bone cement, a novel material, can reduce local thrombosis. We used a simple and reproducible animal model to confirm th...

    Authors: Linchao Sang, Kangning Hao, Luobin Ding, Xiaoyu Shen, Hui Sun, Dehao Fu and Xiangbei Qi
    Citation: BMC Musculoskeletal Disorders 2022 23:513
  18. The autogenous iliac bone graft is the first choice of surgical treatment for long bone non-union. However, many factors limit the use of autogenous bone, such as insufficient bone harvest and complications in...

    Authors: Shenghui Wu, Kun Quan, Jiong Mei, Min Dai and Sa Song
    Citation: BMC Musculoskeletal Disorders 2022 23:512
  19. Continuous subcutaneous insulin infusion (CSII) for the treatment of type 2 diabetes (T2D) can improve the structure and strength of femur of rats, but the effect of CSII treatment on the lumbar spine of T2D r...

    Authors: Xiaorong Hu, He Gong, Aiqi Hou, Xiaodan Wu, Peipei Shi and Yingying Zhang
    Citation: BMC Musculoskeletal Disorders 2022 23:511
  20. Deep learning (DL) is an advanced machine learning approach used in diverse areas, such as image analysis, bioinformatics, and natural language processing. A convolutional neural network (CNN) is a representat...

    Authors: Hyunkwang Shin, Gyu Sang Choi, Oog-Jin Shon, Gi Beom Kim and Min Cheol Chang
    Citation: BMC Musculoskeletal Disorders 2022 23:510
  21. Low back pain (LBP) is associated with lumbar disc degeneration (LDD) and fatty infiltration of paraspinal muscles. However, there are some controversies about the relationship between LDD and fatty infiltrati...

    Authors: Liqiang Shi, Bin Yan, Yucheng Jiao, Zhe Chen, Yuehuan Zheng, Yazhou Lin and Peng Cao
    Citation: BMC Musculoskeletal Disorders 2022 23:509
  22. Chronic spinal epidural hematomas (SEHs) are rare clinical entities. SEH with vertebral scalloping is extremely rare, with only a few cases having been reported to date. We report a unique case of spontaneous ...

    Authors: Shusaku Fukatsu, Satoshi Ogihara, Hiroki Imada, Satoshi Ikemune, Jun-Ichi Tamaru and Kazuo Saita
    Citation: BMC Musculoskeletal Disorders 2022 23:508
  23. Pain catastrophizing in preoperative total knee arthroplasty (TKA) patients is associated with several poorly characterised factors in the literature. This study investigated the current state and associated f...

    Authors: Juhong Pei, Haixia Chen, Tong Ma, Ying Zhang, Xiangfu Wang, Chenxu Li, Binglin Ye, Xingsheng Wang, Jirong Zhao and Xinman Dou
    Citation: BMC Musculoskeletal Disorders 2022 23:507
  24. The Ponseti method is the gold standard for clubfoot treatment. However, relapse and residual gait deviations are common, and follow-up until 7 years of age is recommended. We evaluated the reliability of the ...

    Authors: Evgenia Manousaki, Hanneke Andriesse, Gunnar Hägglund, Axel Ström and Anna-Clara Esbjörnsson
    Citation: BMC Musculoskeletal Disorders 2022 23:506
  25. Approximately 30% to 40% of older adults have hyperkyphosis, defined as excessive curvature of the thoracic spine. Hyperkyphosis is associated with increased morbidity and mortality. This study aimed to determ...

    Authors: Yoshimi Fukuoka, Wendy B. Katzman, Amy Gladin, Nancy E. Lane, Deborah M. Kado and Yoo Jung Oh
    Citation: BMC Musculoskeletal Disorders 2022 23:505
  26. The axial headless compression screw (AHCS) technique is a widely used method for distal interphalangeal joint (DIPJ) and thumb IPJ arthrodesis. However, it might not be suitable for cases over 10° flexion of ...

    Authors: Seung Hun Woo, Sang Ho Kwak, Hyo Seok Jang, Dong Hee Kim, Jang Hyeon Seo and Sang Hyun Lee
    Citation: BMC Musculoskeletal Disorders 2022 23:504
  27. The type, timing, and extent of provision of rehabilitation for lumbar discectomy patients in the UK are currently unknown. The aim of this study was to determine the provision and type of rehabilitation for p...

    Authors: Hanan Alsiaf, Terence W. O’Neill, Michael J. Callaghan and Peter C. Goodwin
    Citation: BMC Musculoskeletal Disorders 2022 23:503
  28. Lumbar spinal stenosis (LSS) is one of the most frequent indications for spine surgery. Open decompression and fusion surgery was the most common treatment and used to be regarded as the golden standard treatm...

    Authors: Shuheng Zhai, Wenkui Zhao, Bin Zhu, Xin Huang, Chen Liang, Bao Hai, Lixiang Ding, Hongwei Zhu, Xianhai Wang, Feng Wei, Hongling Chu and Xiaoguang Liu
    Citation: BMC Musculoskeletal Disorders 2022 23:502
  29. To describe success and failure (S&F) after lumbar spine surgery in terms equally understandable across the entire health ecosystem.

    Authors: Albert V B Brasil, Maiara Anschau Floriani, Ericson Sfreddo, Tobias Ludwig do Nascimento, Andriele Abreu Castro, Luana Giongo Pedrotti, Marina Bessel, Juçara Gasparetto Maccari, Mohamed Parrini Mutlaq and Luiz Antonio Nasi
    Citation: BMC Musculoskeletal Disorders 2022 23:501
  30. Osteochondral lesion of the talus (OLT) is one of the most common ankle injuries, which will lead to biomechanical changes in the ankle joint and ultimately affect ankle function. Finite element analysis (FEA)...

    Authors: Jia Li, Yezhou Wang, Yu Wei, Dan Kong, Yuan Lin, Duanyang Wang, Shi Cheng, Pengbin Yin and Min Wei
    Citation: BMC Musculoskeletal Disorders 2022 23:500
  31. Osteonecrosis of the femoral head (ONFH) may occur in the adolescent and younger adults (AYAs). Total hip arthroplasty (THA) is not the best treatment option for younger patients. Surgical hip dislocation (SHD...

    Authors: Wenhuan Chen, Jianxiong Li, Wenxuan Guo, Shihua Gao, Qiushi Wei, Ziqi Li and Wei He
    Citation: BMC Musculoskeletal Disorders 2022 23:499
  32. To evaluate the difference in surgical planning of osteotomies around the knee between preoperative standing and supine radiographs and to identify risk factors for discrepancies in surgical planning.

    Authors: Shuntaro Nejima, Ken Kumagai, Shunsuke Yamada, Masaichi Sotozawa, Dan Kumagai, Hironori Yamane and Yutaka Inaba
    Citation: BMC Musculoskeletal Disorders 2022 23:497
  33. In bicruciate-stabilized total knee arthroplasty (BCS-TKA), the relationship between the postoperative kinematics and sports subscales in patient-reported outcome measures (PROMs) remains unknown. The purpose ...

    Authors: Kenichi Kono, Hiroshi Inui, Tomofumi Kage, Tetsuya Tomita, Takaharu Yamazaki, Shuji Taketomi, Ryota Yamagami, Kohei Kawaguchi and Sakae Tanaka
    Citation: BMC Musculoskeletal Disorders 2022 23:496
  34. Heat shock protein (HSP) 90 functions as a molecular chaperone and is constitutively expressed and induced in response to stress in many cell types. We have previously demonstrated that transforming growth fac...

    Authors: Gen Kuroyanagi, Haruhiko Tokuda, Kazuhiko Fujita, Tetsu Kawabata, Go Sakai, Woo Kim, Tomoyuki Hioki, Junko Tachi, Rie Matsushima-Nishiwaki, Takanobu Otsuka, Hiroki Iida and Osamu Kozawa
    Citation: BMC Musculoskeletal Disorders 2022 23:495
  35. Monoiodoacetate (MIA)-induced arthritis models are used widely in osteoarthritis (OA) research to develop effective conservative treatments for hip OA, as an alternative to joint replacement surgery. In joint ...

    Authors: Satoshi Yoh, Yuya Kawarai, Shigeo Hagiwara, Sumihisa Orita, Junichi Nakamura, Shuichi Miyamoto, Takane Suzuki, Tsutomu Akazawa, Yuki Shiko, Yohei Kawasaki and Seiji Ohtori
    Citation: BMC Musculoskeletal Disorders 2022 23:494
  36. A spinal cord injury (SCI) is a devastating, life-changing event that has profoundly deleterious effects on an individual’s health and well-being. Dysregulation of neuromuscular, cardiometabolic, and endocrine...

    Authors: K. F. Reid, T. W. Storer, K. M. Pencina, R. Valderrabano, N. K. Latham, L. Wilson, C. Ghattas, R. Dixon, A. Nunes, N. Bajdek, G. Huang, S. E. Skeels, A. P. Lin, S. M. Merugumala, H. J. Liao, M. L. Bouxsein…
    Citation: BMC Musculoskeletal Disorders 2022 23:493
  37. Effective symptom control in painful knee osteoarthritis (OA) may improve patient quality of life. In a randomised crossover trial (NCT03381248), COOLIEF* cooled radiofrequency ablation (CRFA) reduced pain and...

    Authors: Mehul J. Desai, Anthony Bentley and William A. Keck
    Citation: BMC Musculoskeletal Disorders 2022 23:491
  38. Patients suffering cartilage defects of the medial compartment with underlying varus deformity do benefit from high tibial osteotomy (HTO) even in the long term. Nonetheless, kinematic and geometric changes es...

    Authors: Lisa Bode, Jan Kühle, Anna-Sophie Brenner, Viola Freigang, Helge Eberbach, Philipp Niemeyer, Norbert P. Südkamp, Hagen Schmal and Gerrit Bode
    Citation: BMC Musculoskeletal Disorders 2022 23:489
  39. Low back pain has been associated with obesity or with being overweight. However, there are no high-quality systematic reviews that have been conducted on the effect of all types of weight loss programs focuse...

    Authors: Lu Hsi Chen, Kirsten Weber, Saba Mehrabkhani, Sarmina Baskaran, Thomas Abbass and Luciana Gazzi Macedo
    Citation: BMC Musculoskeletal Disorders 2022 23:488
  40. Smartphones provide opportunities for musculoskeletal research: they are integrated in participants’ daily lives and can be used to collect patient-reported outcomes as well as sensor data from large groups of...

    Authors: Anna L. Beukenhorst, Katie L. Druce and Diederik De Cock
    Citation: BMC Musculoskeletal Disorders 2022 23:487
  41. Osteoarthritis (OA) is the most common joint disease, and is most frequently seen in the knees. However, there is no effective therapy to relieve the progression of knee OA. Metformin is a safe, well-tolerated...

    Authors: Guangfeng Ruan, Shiwen Yuan, Aiju Lou, Yingqian Mo, Yuan Qu, Dongmei Guo, Shangqi Guan, Yan Zhang, Xiaoyong Lan, Jun Luo, Yifang Mei, Hongwei Zhang, Weirong Wu, Lie Dai, Qinghong Yu, Xiaoyan Cai…
    Citation: BMC Musculoskeletal Disorders 2022 23:486
  42. Osteogenesis Imperfecta affects approximately 1 in every 10,000 people. Musculoskeletal disorders and pain are common in adults with Osteogenesis Imperfecta, but specific knowledge of the problems people have ...

    Authors: Sophie Barlow, Lucy Dove, Anju Jaggi, Richard Keen and Judith Bubbear
    Citation: BMC Musculoskeletal Disorders 2022 23:485
  43. There is no agreement about the best reconstructive option following resection of proximal humerus tumors. The purpose of this study was to compare the functional outcomes of endoprosthesis reconstruction vers...

    Authors: Walid Atef Ebeid, Sherif Eldaw, Ismail Tawfeek Badr, Mohamed Kamal Mesregah and Bahaa Zakarya Hasan
    Citation: BMC Musculoskeletal Disorders 2022 23:484
  44. Computer-assisted preoperative planning, combined with PSI has become an effective technique for treating complex limb deformities. The purpose of this study was to evaluate the efficacy and safety of the nove...

    Authors: Xin-long Ma, Jian-xiong Ma, Xing-wen Zhao, Yu-ren Du, Ying Wang, Hao-hao Bai and Bin Lu
    Citation: BMC Musculoskeletal Disorders 2022 23:483
  45. Femoral neck fractures are the worst consequence of osteoporosis (OP), and its early prevention and treatment have become a public health problem. This study aims to investigate the relationship of bone-relate...

    Authors: Ning Xia, Yun Cai, Wei Wang, Chen Bao, Yunming Li, Qingyun Xie, Wei Xu and Da Liu
    Citation: BMC Musculoskeletal Disorders 2022 23:482
  46. Fracture nonunion/delayed union seriously affects physical and mental health and quality of life. The aim of this study was to evaluate the relative efficacy of different adjuvant treatments for nonunion/delay...

    Authors: Jun Yang, Xiangmin Zhang, Wangbo Liang, Guo Chen, Yanbo Ma, Yonghua Zhou, Rong Fen and Kaichang Jiang
    Citation: BMC Musculoskeletal Disorders 2022 23:481

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