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  1. Although articular cartilage is the primary tissues affected by osteoarthritis (OA), the underlying subchondral bone also undergoes noticeable changes. Despite the growing body of research into the biophysical...

    Authors: Qiliang Zuo, Shifeier Lu, Zhibin Du, Thor Friis, Jiangwu Yao, Ross Crawford, Indira Prasadam and Yin Xiao
    Citation: BMC Musculoskeletal Disorders 2016 17:367
  2. To investigate the effect of baseline clinical characteristics and glucocorticoid treatment on temporal artery biopsy (TAB) findings in patients with giant cell arteritis (GCA).

    Authors: Karin Jakobsson, Lennart Jacobsson, Aladdin J. Mohammad, Jan-Åke Nilsson, Kenneth Warrington, Eric L. Matteson and Carl Turesson
    Citation: BMC Musculoskeletal Disorders 2016 17:363
  3. Despite numerous options for treating back pain and the increasing healthcare resources devoted to this problem, the prevalence and impact of back pain-related disability has not improved. It is now recognized...

    Authors: Dan Cherkin, Benjamin Balderson, Georgie Brewer, Andrea Cook, Katherine Talbert Estlin, Sarah C. Evers, Nadine E. Foster, Jonathan C. Hill, Rene Hawkes, Clarissa Hsu, Mark Jensen, Anne-Marie LaPorte, Martin D. Levine, Diane Piekara, Pam Rock, Karen Sherman…
    Citation: BMC Musculoskeletal Disorders 2016 17:361
  4. African Americans bear a disproportionate burden of osteoarthritis (OA), with higher prevalence rates, more severe pain, and more functional limitations. One key barrier to addressing these disparities has bee...

    Authors: Leah A. Schrubbe, Scott G. Ravyts, Bernadette C. Benas, Lisa C. Campbell, Crystal W. Cené, Cynthia J. Coffman, Alexander H. Gunn, Francis J. Keefe, Caroline T. Nagle, Eugene Z. Oddone, Tamara J. Somers, Catherine L. Stanwyck, Shannon S. Taylor and Kelli D. Allen
    Citation: BMC Musculoskeletal Disorders 2016 17:359
  5. The purpose of the present study was to check the validity of data collected in BIOREG, the Austrian register for biological treatment in rheumatology, and to elucidate eventual differences with respect to dis...

    Authors: Bernhard Rintelen, Jochen Zwerina, Manfred Herold, Franz Singer, Johann Hitzelhammer, Wolfgang Halder, Gabriela Eichbauer-Sturm, Rudolf Puchner, Miriam Stetter and Burkhard F. Leeb
    Citation: BMC Musculoskeletal Disorders 2016 17:358

    The Erratum to this article has been published in BMC Musculoskeletal Disorders 2016 17:412

  6. Current glenoid defect measurement techniques only quantify bone loss in terms of defect diameter or surface. However, the glenoid depth plays an important role in shoulder stabilization by means of concavity ...

    Authors: Philipp Moroder, Franziska Haniel, Michael Quirchmayr, Eva Schulz, Manfred Eppel, Nicholas Matis, Alexander Auffarth and Herbert Resch
    Citation: BMC Musculoskeletal Disorders 2016 17:357
  7. There are many different reasons why patients could be experiencing pain in the gluteal area. Previous studies have shown an association between radicular low back pain (LBP) and gluteal pain (GP). Studies loc...

    Authors: Guofang Fang, Jianhe Zhou, Yutan Liu, Hongxun Sang, Xiangyang Xu and Zihai Ding
    Citation: BMC Musculoskeletal Disorders 2016 17:356
  8. The Goutallier Classification is a semi quantitative classification system to determine the amount of fatty degeneration in rotator cuff muscles. Although initially proposed for axial computer tomography scans...

    Authors: Fabian Gilbert, Dirk Böhm, Lars Eden, Jonas Schmalzl, Rainer H. Meffert, Herbert Köstler, Andreas M. Weng and Dirk Ziegler
    Citation: BMC Musculoskeletal Disorders 2016 17:355
  9. Clinical guidelines recommend a combination of physical, pharmacological and psychological treatments for chronic widespread pain, but published accounts of treatment acceptability are lacking.

    Authors: Penny Bee, John McBeth, Gary J. MacFarlane and Karina Lovell
    Citation: BMC Musculoskeletal Disorders 2016 17:354
  10. Anti-Tumor Necrosis Factor (TNF) therapies are able to control rheumatoid arthritis (RA) disease activity and limit structural damage. Yet no predictive factor of response to anti-TNF has been identified. Meta...

    Authors: Zuzana Tatar, Carole Migne, Melanie Petera, Philippe Gaudin, Thierry Lequerre, Hubert Marotte, Jacques Tebib, Estelle Pujos Guillot and Martin Soubrier
    Citation: BMC Musculoskeletal Disorders 2016 17:353
  11. Dopamine receptor 2 (DR2) expressions on B cells from Rheumatoid arthritis (RA) patients has been found to be negatively correlated with disease activity and can potentially predict the response to treatment. ...

    Authors: Lei Wei, Ying Sun, Xiu-Fang Kong, Chi Zhang, Tao Yue, Qi Zhu, Dong-Yi He and Lin-Di Jiang
    Citation: BMC Musculoskeletal Disorders 2016 17:352
  12. Physical exercises and physiotherapy are of great importance for maintenance of joint function in patients with rheumatoid arthritis (RA). However, many RA patients complain about problems to receive prescript...

    Authors: Jan Zernicke, Claudia Kedor, Angela Müller, Gerd-Rüdiger Burmester, Anett Reißhauer and Eugen Feist
    Citation: BMC Musculoskeletal Disorders 2016 17:351
  13. Pressure pain thresholds (PPT) are commonly used to quantify mechanical pain sensitivity of deep structures. Excellent PPT reliability has been previously reported among the low back of healthy subjects. Howev...

    Authors: Romain Balaguier, Pascal Madeleine and Nicolas Vuillerme
    Citation: BMC Musculoskeletal Disorders 2016 17:350
  14. Following lumbar fusion surgery, a successful outcome is empirically linked to effective rehabilitation. While rehabilitation is typically postoperative, the phase before surgery – termed prehabilitation – is rep...

    Authors: Hanna Lotzke, Max Jakobsson, Helena Brisby, Annelie Gutke, Olle Hägg, Rob Smeets, Marlies den Hollander, Lars-Eric Olsson and Mari Lundberg
    Citation: BMC Musculoskeletal Disorders 2016 17:349
  15. Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation and joint structural deterioration. Driven by recent expectations that patients in clinical trials randomized to placebo ...

    Authors: Jeroen P. Jansen, Maria-Cecilia Vieira, John D. Bradley, Joseph C. Cappelleri, Samuel H. Zwillich and Gene V. Wallenstein
    Citation: BMC Musculoskeletal Disorders 2016 17:348
  16. The aim of this study was to investigate effects on perceived exertion, work ability self-reported neck pain and clinically diagnosed conditions in the neck, of an intervention with prismatic spectacles among ...

    Authors: Agneta Lindegård, Catarina Nordander, Helene Jacobsson and Inger Arvidsson
    Citation: BMC Musculoskeletal Disorders 2016 17:347
  17. Giant cell tumors (GCTs) located in the distal radius are likely to recur, and the treatment of such recurrent tumors is very difficult. Here, we report our clinical experience in distal radius reconstruction ...

    Authors: Yun-fa Yang, Jian-wei Wang, Pin Huang and Zhong-he Xu
    Citation: BMC Musculoskeletal Disorders 2016 17:346
  18. Dupuytren’s disease is a common fibrotic disorder of the palm characterized by the development of progressive flexion deformities in the digits, leading to significant functional impairment. Surgical excision ...

    Authors: Catherine Ball, David Izadi, Liaquat Suleman Verjee, James Chan and Jagdeep Nanchahal
    Citation: BMC Musculoskeletal Disorders 2016 17:345
  19. Multiple small drilling for core decompression is widely used to preserve the femoral head in patients with avascular necrosis of the femoral head (ANFH). Nevertheless, the clinical outcome remains controversi...

    Authors: Han Yin, Zhenfeng Yuan and Dawei Wang
    Citation: BMC Musculoskeletal Disorders 2016 17:344
  20. Simple bone cysts are common benign lytic bone lesions in children. The main goals of treatment for bone cysts are to prevent pathological fractures, support the healing process, and prevent recurrence. This r...

    Authors: Wenchao Li, Ruijiang Xu, Minghua Du and Hui Chen
    Citation: BMC Musculoskeletal Disorders 2016 17:343
  21. To report the predictive value of nail-fold capillaroscopy (NFC) patterns of vasculopathy for systemic sclerosis (Scleroderma; SSc) in an unselected cohort of patients with Raynaud’s phenomenon (RP).

    Authors: Lesley-Anne Bissell, Giuseppina Abignano, Paul Emery, Francesco Del Galdo and Maya H. Buch
    Citation: BMC Musculoskeletal Disorders 2016 17:342
  22. Sagittal spinopelvic alignment changes associated with degenerative facet joint arthritis have been assessed in a few studies. It has been documented that patients with facet joint degeneration have higher pel...

    Authors: Xin Lv, Yuan Liu, Song Zhou, Qiang Wang, Houyun Gu, Xiaoxing Fu, Yi Ding, Bin Zhang and Min Dai
    Citation: BMC Musculoskeletal Disorders 2016 17:341
  23. Frozen shoulder is a common yet poorly understood musculoskeletal condition, which for many, is associated with substantial and protracted morbidity. Understanding the pathology associated with this condition ...

    Authors: Victoria Ryan, Hazel Brown, Catherine J. Minns Lowe and Jeremy S. Lewis
    Citation: BMC Musculoskeletal Disorders 2016 17:340
  24. Patients with systemic sclerosis (SSc) are endagered by tissue fibrosis and by microvasculopathy, with the latter caused by endothelial cell expansion/proliferation. SSc-associated fibrosis potentially results...

    Authors: S. Patschan, D. Tampe, C. Müller, C. Seitz, C. Herink, G. A. Müller, E. Zeisberg, M. Zeisberg, E. Henze and D. Patschan
    Citation: BMC Musculoskeletal Disorders 2016 17:339
  25. The incidence and severity of football-related injuries has been found to differ strongly between professional leagues from different countries. The aims of this study were to record the incidence, type and se...

    Authors: I. Shalaj, F. Tishukaj, N. Bachl, H. Tschan, B. Wessner and R. Csapo
    Citation: BMC Musculoskeletal Disorders 2016 17:338
  26. We examined pain levels in 2 cohorts assembled from the British Society for Rheumatology Biologics Register (BSRBR), and investigated which factors predicted Bodily Pain scores and discontinuation of TNFα-inhi...

    Authors: Daniel F. McWilliams and David A. Walsh
    Citation: BMC Musculoskeletal Disorders 2016 17:337
  27. Improving vitamin D (25-OHD) status may be an important modifiable factor that could reduce disability severity, fall-rates and mortality associated after hip fracture surgery. Providing a loading-dose post-su...

    Authors: Jenson CS Mak, Rebecca S. Mason, Linda Klein and Ian D. Cameron
    Citation: BMC Musculoskeletal Disorders 2016 17:336
  28. Both osteoarthritis (OA) and cardiovascular diseases (CVD) are prevalent conditions which often co-exist. Vascular involvement in the pathogenesis of these diseases, as well as increased cardiovascular risk in...

    Authors: Kaspar Tootsi, Aare Märtson, Mihkel Zilmer, Kaido Paapstel and Jaak Kals
    Citation: BMC Musculoskeletal Disorders 2016 17:335
  29. There are two primary surgical techniques to reconstruct the anterior cruciate ligament (ACL), transtibial (TT) technique and anteromedial portal (AMP) technique. Currently, there is no consensus which surgica...

    Authors: Simeon J. S. Ruiter, Reinoud W. Brouwer, Tim W. G. M. Meys, Cornelis H. Slump and Jos J. A. M. van Raay
    Citation: BMC Musculoskeletal Disorders 2016 17:334
  30. The concerns about the development of adverse events (AEs) in elderly RA patients as a result of age-related changes in drug metabolism and the presence of comorbid illnesses are emphasizing due to increasing ...

    Authors: Soo-Kyung Cho, Yoon-Kyoung Sung, Dam Kim, Soyoung Won, Chan-Bum Choi, Tae-Hwan Kim, Jae-Bum Jun, Dae-Hyun Yoo and Sang-Cheol Bae
    Citation: BMC Musculoskeletal Disorders 2016 17:333
  31. Case reports have linked adult hypophosphatasia as a possible cause of atypical femur fractures (AFF) associated with bisphosphonate use. Adult hypophosphatasia is an asymptomatic genetic condition which resul...

    Authors: Timothy Bhattacharyya, Smita Jha, Hongying Wang, Daniel L. Kastner and Elaine F. Remmers
    Citation: BMC Musculoskeletal Disorders 2016 17:332
  32. Treatment with non-steroidal anti-inflammatory drugs (NSAID) is a common component of treatment regimens for rheumatoid arthritis (RA). Etoricoxib is a COX-2 selective NSAID that has demonstrated efficacy in t...

    Authors: Kara Bickham, Alan J. Kivitz, Anish Mehta, Nancy Frontera, Sandhya Shah, Paul Stryszak, Zoran Popmihajlov and Paul M. Peloso
    Citation: BMC Musculoskeletal Disorders 2016 17:331
  33. Surveys of patient satisfaction and their willingness to return can be used for the optimization of processes, improving their quality, and increasing the satisfaction and loyalty in customers. This study look...

    Authors: Tom Schaal, Tonio Schoenfelder, Joerg Klewer and Joachim Kugler
    Citation: BMC Musculoskeletal Disorders 2016 17:330
  34. Relative young and more active patients with osteoarthritis (OA) of the isolated medial femorotibial compartment in conjunction with anterior cruciate ligament (ACL) deficiency are difficult to treat. The aim ...

    Authors: Shaoqi Tian, Bin Wang, Yuanhe Wang, Chengzhi Ha, Lun Liu and Kang Sun
    Citation: BMC Musculoskeletal Disorders 2016 17:327
  35. This study assessed the incidence and excess mortality of hip fractures among inpatients aged 20–40 years in a nationwide population database in Taiwan.

    Authors: Tsai-Hsueh Leu, Wei-Chun Chang, Jeff Chien-Fu Lin, Chi Lo, Wen-Miin Liang, Yu-Jun Chang, Dann-Pyng Shih, Cheng-Chun Wu, Chi-Fung Cheng and Sy-Jye Wei
    Citation: BMC Musculoskeletal Disorders 2016 17:326
  36. Norwegian Psychomotor Physiotherapy (NPMP) has been an established treatment approach for more than 50 years, although mostly in the Scandinavian countries, and is usually applied to patients with widespread a...

    Authors: Tove Dragesund and Alice Kvåle
    Citation: BMC Musculoskeletal Disorders 2016 17:325
  37. There is evidence that postmenopausal women with rheumatoid arthritis (RA) on glucocorticoid (GC) therapy and bisphosphonate (BP) have an increased risk for atypical subtrochanteric and atypical diaphyseal fem...

    Authors: Rahel Meinen, Inna Galli-Lysak, Peter M. Villiger and Daniel Aeberli
    Citation: BMC Musculoskeletal Disorders 2016 17:324
  38. Epidemic myalgia is a disease that presents with fever and extreme myalgia of the trunk due to an acute enterovirus infection. The trunk pain is mainly in the chest or in the epigastrium. We aimed to highlight...

    Authors: Tsuneaki Kenzaka, Yukariko Hida, Masanori Matsumoto and Hozuka Akita
    Citation: BMC Musculoskeletal Disorders 2016 17:323
  39. Infections are a common complication of RA with associated morbidity and mortality. The aetiology of increased risk is complex and multifactorial. Despite this, strategies to mitigate against risk of infection...

    Authors: Sujith Subesinghe, Andrew Ian Rutherford, Fowzia Ibrahim, Helen Harris and James Galloway
    Citation: BMC Musculoskeletal Disorders 2016 17:322
  40. Juvenile idiopathic arthritis (JIA) refers to a number of rare chronic inflammatory diseases. Although JIA imposes a significant societal burden, limited data are available on the cost of JIA. The study’s obje...

    Authors: Aris Angelis, Panos Kanavos, Julio López-Bastida, Renata Linertová and Pedro Serrano-Aguilar
    Citation: BMC Musculoskeletal Disorders 2016 17:321
  41. In Japan, the majority of hip osteoarthritis (OA) was caused by acetabular dysplasia, and about 90 % of patients were female. The present study focused on Japanese female patients with hip OA due to acetabular...

    Authors: Satoko Ohfuji, Seiya Jingushi, Kyoko Kondo, Muroto Sofue, Moritoshi Itoman, Tadami Matsumoto, Yoshiki Hamada, Hiroyuki Shindo, Yoshio Takatori, Harumoto Yamada, Yuji Yasunaga, Hiroshi Ito, Satoshi Mori, Ichiro Owan, Genji Fujii, Hirotsugu Ohashi…
    Citation: BMC Musculoskeletal Disorders 2016 17:320
  42. Autologous blood transfusion (ABT) drainage system is a new unwashed salvaged blood retransfusion system for total knee replacement (TKA). However, whether to use ABT drainage, closed-suction (CS) drainage or ...

    Authors: Kun-hao Hong, Jian-ke Pan, Wei-yi Yang, Ming-hui Luo, Shu-chai Xu and Jun Liu
    Citation: BMC Musculoskeletal Disorders 2016 17:142
  43. It is recognised that back pain (BP) is a debilitating medical problem in the soldier community, which limits operational readiness as well as work ability. As such, identification of risk factors is a necessi...

    Authors: Andreas Monnier, Mats Djupsjöbacka, Helena Larsson, Kjell Norman and Björn O. Äng
    Citation: BMC Musculoskeletal Disorders 2016 17:319
  44. Tibiotalocalcaneal arthrodesis (TTCA) using intramedullary nails is a salvage procedure for many diseases in the ankle and subtalar joint. Despite “newly described intramedullary nails” with specific anatomica...

    Authors: Julia Evers, Martin Schulze, Dominic Gehweiler, Martin Lakemeier, Michael J. Raschke, Dirk Wähnert and Sabine Ochman
    Citation: BMC Musculoskeletal Disorders 2016 17:318
  45. Chronic musculoskeletal pain (CMP) in adolescents can influence functioning and well-being, and has negative consequences for families and society as well. According to the Fear Avoidance Model, fear of moveme...

    Authors: Carolien Dekker, Mariëlle E. J. B. Goossens, Caroline H. G. Bastiaenen and Jeanine A. M. C. F. Verbunt
    Citation: BMC Musculoskeletal Disorders 2016 17:317
  46. Behavioral medicine (BM) treatment is recommended to be implemented for pain management in physical therapy. Its implementation requires physical therapists (PTs), who are skilled at performing functional beha...

    Authors: C. Emilson, P. Åsenlöf, S. Pettersson, S. Bergman, M. Sandborgh, C. Martin and I. Demmelmaier
    Citation: BMC Musculoskeletal Disorders 2016 17:316
  47. Intravenous tranexamic acid (IV TXA) is one of the most effective agents in use for reducing blood loss following total knee arthroplasty (TKA) but its safety regarding venous thromboembolic events (VTEs) rema...

    Authors: P Pinsornsak, S Rojanavijitkul and S Chumchuen
    Citation: BMC Musculoskeletal Disorders 2016 17:313

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