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Contributions of musculoskeletal rehabilitation in patients after chikungunya fever: a systematic review



Chikungunya fever is an infection transmitted by the Chikungunya virus (CHIKV), which is an arbovirus that is transmitted by the mosquitoes Aedes aegypti and Aedes albopictus. The most common sequelae caused by CHIKV are chronic musculoskeletal pain, nerve damage, joint deformation and functional impairment.


To systematically identify the literature on the contributions of physiotherapy in the treatment of patients with CHIKV sequelae.

Materials and methods

Systematic review of the literature, guided by the recommendations of the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA). The databases used were PUBMED, LILACS, Scielo and PEDro. Experimental studies and/or full case studies published without language restriction or publication data were included, in which they stood out as contributions of musculoskeletal functional rehabilitation in the treatment of patients with the condition in question. Analytical observational studies, editorial letters, review protocols, reflective studies, literature reviews and articles that do not have an abstract and/or full text available online were excluded.


The search in the databases was carried out between July and August 2022. A total of 4,782 articles were found on the platforms used and 10 articles from the gray literature search. After the duplicate analysis, 2,027 studies were excluded, leaving 2,755 articles that had their titles and abstracts read, of which 600 articles were selected for full reading. After this step, a final sample of 13 articles was eligible for this review.

Final considerations

The most consolidated approaches used in the literature demonstrate that kinesiotherapy, associated or not with electrothermophototherapy, the pilates method and auriculotherapy are useful resources in the treatment of these individuals, significantly inspired by pain relief, improved quality of life and of functionality.

Peer Review reports


The Chikungunya virus (CHIKV) is a viral disease transmitted by mosquitoes that has become an important public health problem in Brazil in recent years [1]. According to the Brazilian Ministry of Health, between 2014 and 2020, there were more than 1.9 million suspected cases of CHIKV in Brazil, with the highest incidence rates observed in the Northeast and Southeast regions of the country [2]. Rio Grande do Norte (RN), located in the northeast region of Brazil, with a population of around 3.5 million people, had the highest incidence rate, almost six times higher than the national rate (723.1 cases per 100 thousand inhabitants) and 37 deaths caused by the disease [3, 4].

The main symptoms of the acute phase of chikungunya fever occur suddenly with high fever, polyarthralgia and intense myalgia, rash, periarticular edema, fatigue and other symptoms, which appear continuously or inconsistently [1]. Those that affect the joint system, lasting longer than three months is characterized as chronic, being capable of lasting for years or resulting in permanent inflammatory joint disease [2, 5].

In the chronic phase of fever, the functional disability and quality of life of individuals affected by this inflammatory process in the joints can be directly affected [6]. These microlesions, continuously, end up leading to the degradation of bone structures, thus affecting activities of daily living (ADLs), leading to a reduction in their autonomy and Independence [2, 7, 8].

In this sense, the physical rehabilitation process of patients plays a key role in maintaining the functionality of individuals in the chronic phase of the disease, helps to break down of adhesions, influencing the cellular processes of healing, improving lubrication and restoring normal joint mechanics [9]. So, rehabilitation treatment, through a well-structured treatment program, can be useful in the treatment of chronic degenerative joint diseases and/or persistent polyarthralgia [9, 10]. Physiotherapy can be a stand-alone alternative to drugs in the management of joint, tendon and nerve-related pains [10].

Despite being considered an effective treatment in post-Chikungunya fever recovery, there are still few studies that address the effectiveness of physiotherapeutic procedures, mainly systematic reviews, and this study is the first to address this important issue. In addition, this study was carried out due to the scarcity of scientific materials with high methodological quality. Thus, this review will serve as a guide for conduct and approaches for professionals working in the field of musculoskeletal functional rehabilitation. In this sense, this review aimed to systematically identify the literature on the contributions of musculoskeletal rehabilitation in post-chikungunya fever patients.


This study is a systematic review of the literature, following the recommendations of the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) [11]. Registration with PROSPERO was carried out, with the approval code: CRD42022363345.

Identification of the research question

In formulating the research question, the PICO (Population, Intervention, Comparison and Outcomes) strategy, proposed by the Joanna Brigs institute [12]. was used to guide the research problem, thus defining: Population (patients with post-traumatic chikungunya fever); Intervention (musculoskeletal rehabilitation); Comparison (placebo/control) and Outcomes (quality of life, functionality, pain). Thus, the following research question was formulated: “What are the contributions of musculoskeletal rehabilitation in patients with persistent manifestations after CHIKV fever?”. We used “‘’chikungunya fever’’ and functionality as keywords, both were indexed in the Descriptors in Health Sciences/Medical Subject Headings - DeCS/MeSH.

Identification of relevant studies

This stage was based on meetings with the research team, which defined the planned approach, the eligibility criteria for the studies, the selected databases, as well as the research strategy with their respective descriptors. The eligibility criteria were: experimental studies and/or complete case studies published without language restriction or publication date, in which the contributions of musculoskeletal rehabilitation in the treatment of patients with the condition in question were highlighted.

Observational studies, editorial letters, review protocols, reflection studies, any literature reviews and articles that do not have an abstract and/or full text available online were excluded.

The identification of studies was carried out through an electronic search in the following databases: PUBMED, Latin America and Caribbean Literature in Health Sciences (LILACS), Scielo and on the PEDro platform. The choice of these databases was due to the wide coverage of international and national studies, with public access or available through a library, in addition to the large collection of manuscripts related to the topic.

A review of all reference lists of included studies was also performed to identify additional relevant studies. To also ensure that all relevant information was captured, searches were carried out in a variety of gray literature sources, such as theses and dissertations databases, (inter)national conference proceedings, and in the reference list of selected articles, to identify studies, reports, and conference abstracts relevant to this review.

For gray literature analysis, an extra researcher was invited (JSCD). This researcher was informed about the research objectives and the descriptor used, in order to make an independent search in the gray literature.

Selection of studies

The selection of studies took place in two stages: in the first, there was a review of titles and abstracts through the Rayyan platform (, eliminating all duplicate articles for this phase [13]. The second stage consisted of reviewing the title and abstract of the eligible articles, and subsequently, the full texts of the studies selected in the second stage were read. For both stages, the process was carried out by two researchers (WBS and DGL), who were instructed on the eligibility criteria and were responsible for reading and extracting the data, while a third evaluator (JSCD) was responsible for solving problems related to possible doubts and/or divergences in the selection.

Data extraction

Data were extracted using a table developed by the research team, which aims to collect information such as: authors, year, place of publication, outcomes, intervention and expected effects. This instrument was previously tested by all reviewers before its final application, to ensure that the information captured was accurate.

Data collection was performed in pairs, where two reviewers (WBS and DGL) independently extracted data from all included studies. In the end, the study collections of each reviewer were compared to visualize possible discrepancies and, if any, they were reviewed and analyzed by the research group, thus ensuring consistency between reviewers.

Methodological quality

Study quality was assessed using the Joanna Briggs Institute (JBI) assessment tools and recommendations. This assessment aimed to analyze the methodological quality of the studies and determine the extent to which a study addressed the possibility of bias in its design, conduct and analysis [14].

Each study was categorized according to the percentage of positive responses. The risk of bias was considered high when the study obtained up to 49% of answers classified as yes, moderate when it obtained from 50 to 69% of positive responses and low when the study reached more than 70% of the score [11,12,13,14]. The process was conducted by two independent reviewers (WBS and DGL). Disagreements were resolved by another reviewer (JSCD).

Ethical issues and patient and public engagement

No patients were involved in this research. Furthermore, this review did not require ethical approval, as it consisted of analyzing and collecting information from publicly available documents.


The database search was carried out between July and August 2022. A total of 4,782 articles were found on the platforms used and 10 articles from the gray literature search carried out in the CAPES Catalog of Theses and Dissertations After the duplicate analysis, 2,027 studies were excluded, leaving 2,755 articles that had their titles and abstracts read, of these, 600 articles were selected for reading in full. After this step, a final sample of 13 articles was eligible for this review. More details can be found in Fig. 1. While, the characteristics of the included studies are shown in Table 1.

Fig. 1
figure 1

Prism flowchart for systematic reviews

Table 1 Details of the studies included according author, year, population, country, study designer and duration of sequels

Characteristics of the studies

A total of 391 individuals composed the sum of the samples of the included studies, the smallest comprising 1 participant, while the largest sample analyzed 102 patients. Regarding gender, most articles used participants of both sexes (84.7%), except for 2 studies, which were composed only of women and 1 composed only of men (Table 1). Of the 13 articles included, all were published after 2016, carried out in Brazil, and the most used study design was the randomized controlled trial (61.52%) (Table 1).

Time of sequels

More than half of the articles included (53.9%) had participants with post-Chikungunya fever sequels equal to or longer than 3 months.


With regard to outcomes, it was observed that pain intensity was the most explored variable in the literature (92.4%), followed by quality of life (69.3%) and range of motion (38.5%) (Table 2). The perception and change in health status and satisfaction with the treatment used were explored in only two studies (15.4%) [19, 21]. Other variables such as edema (7 0.7%), muscle strength (15.4%), and blood factors (7.7%) [9, 23, 26] were the least observed outcomes.

Table 2 Details of the included studies according to author, year, participants, outcomes and instruments, intervention and effects found


With regard to duration and frequency, it was observed that most of the studies (92.4%) of the sample carried out interventions over five sessions, twice a week. However, only one study [9] had a shorter duration, once a week for four weeks. With regard to the protocols, it was shown that kinesiotherapy associated or not with electrothermophototherapy was the most used therapeutic approach (69.3%), followed by the pilates method and auriculotherapy (15.4% each) [20,21,22].

Effects found

Among the effects found, with regard to people who underwent musculoskeletal rehabilitation, the variable pain intensity was the most expressive in the analyzed literature (84.7%), measured using the visual analogue scale (VAS), McGill Pain Questionnaire and Brief Pain Inventory [16, 17] and the numeric pain scale [18], followed by the quality of life variables (53.9%) measured using the Short Form Health – 36 (SF -36) [19, 21] and 12-item health survey (SF-12) [9]; mobility and balance measured through the timed up and go (TUG) [17, 19, 26] and functional capacity measured by the Health Assessment Questionnaire (HAQ) and short physical performance battery (SPPB) [18]; perception/change in health status and satisfaction, measured by the Patient Global Impression of Change Scale (PGIC) (15.4%) [19, 23, 26]; and range of motion (23.1%), measured using goniometry [17, 20, 22].

Methodological quality

When evaluating the methodological quality and the risk of bias of the selected references, according to the study design, it is observed that most articles (53,83%) have a low risk of bias, with an average of 72.7% of positive responses. Meanwhile, 5 studies (38,45%) were classified as having a moderate risk of bias, with a range between 54.5% and 63.6% [9, 16, 20, 23, 26]. Only one study (7,69%) was classified as having a high risk of bias of 45.4% [24]. Detailed evaluations of each article can be seen in Tables 3 and 4 respectively.

Table 3 Degree of quality of evidence of the included studies
Table 4 Degree of methodological quality and risk of bias


This systematic review aimed to systematically identify the literature on the contributions of musculoskeletal rehabilitation in the treatment of patients with CHIKV sequelae. A scarcity of intervention studies was observed in patients with post-Chikungunya fever sequels, despite the great importance of the topic. This scarcity may be related to the great challenges of working with this population, such as the lack of well-established intervention protocols, ethical issues and high frequencies of chronic sequels and dropout, making it difficult to carry out these studies.

Ribeiro et al. [15] clarifies that the application of low-intensity laser and ultrasound are important in the treatment of chronic rheumatological pathologies, showing that these resources have the objective of reducing inflammation, pain and joint stiffness, seeming to be a good intervention for patients with post-chikungunya fever sequels.

Corroborating with Ribeiro et al. [15], the study by Oliveira and Silva [9] clarifies that persistent polyarthralgia after chikungunya fever is a common clinical manifestation in cases of CHIKV infection. In this scenario, Oliveira and Silva [9] carried out a musculoskeletal rehabilitation program based purely on kinesiotherapy (therapeutic exercises and manual therapy) for four weeks. The results of this study indicated that kinesiotherapy as an isolated treatment was effective in increasing muscle strength, range of motion, decreasing edema and improving functional capacity, in addition to notably contributing to the reduction of pain.

In addition to kinesiotherapy, other studies demonstrate the benefits of the Pilates method in this context, reducing pain in patients with chronic musculoskeletal manifestations after Chikungunya fever. An example of this is the study carried out by Oliveira [18], where two intervention groups were compared (Pilates and the standard treatment), and it was seen that individuals who did Pilates method had a significant improvement in pain and quality of life [21].

The literature also demonstrates that resistance exercise has satisfactory effects in the treatment of rheumatological diseases, and may be a non-pharmacological strategy in the treatment of sequelae caused by CHIKV. In this sense, the study by Neumann [19] carried out a study to develop a protocol of progressive resistance exercises for the treatment of individuals with chronic musculoskeletal manifestations of chikungunya and to evaluate its effectiveness in improving functionality, pain and quality of life. And as a result, the resistance group obtained benefits in improving functionality and reducing pain in patients with chronic musculoskeletal manifestations of chikungunya when compared to control group.

Complementing the evidence above, the study by Silva et al. [23] sought to evaluate the effect of physical exercise on the oxidative balance of lymphomononuclear cells (PBMCs) in patients with chronic infection by the CHIKV. It is observed that oxidative stress can cause damage to cartilage, the main protective tissue of bones, while chronic inflammation causes a series of gradual changes in the immune system. That said, the study showed that a physical exercise protocol, with twelve training sessions, lasting forty minutes and intensity of 50–70% of the maximum heart rate did not minimize oxidative stress in PBMCs of patients with chronic infection by chikungunya after the physical exercise protocol used in this study. The authors suggest new clinical studies in order to consolidate and complement this evidence [23].

Bringing an innovative proposal, the study by Silva-filho et al., [16] sought to investigate the hypothesis that Transcranial Direct Current Stimulation (tDCS) would improve pain and functionality in individuals with chronic arthralgia after Chikungunya fever. In this study, twenty patients in the chronic phase of chikungunya were randomized into two groups, one receiving active tDCS and the other sham tDCS (control). The results of this research showed that tDCS reduces pain levels with clinically significant changes for patients with Chikungunya.

In the scenario of integrative and complementary health practices, the study by Coutinho [17] sought to evaluate the effectiveness of auriculotherapy, complementary to standard drug treatment, in improving pain and mobility of symptomatic individuals after Chikungunya Fever, as well as the predictive factors for disability at different stages of the disease.

Fifty individuals diagnosed with post-Chikungunya fever sequelae were divided into two intervention groups: auriculotherapy at specific acupuncture points and sham auriculotherapy at non-specific points. Both groups received five treatment sessions performed once a week over five weeks. The results demonstrate that auriculotherapy is effective in improving mobility limitation after Chikungunya fever, and that individuals in the acute/subacute phase of the disease have greater disability, with mobility limitation being the main predictor of functional decline.

Corroborating with the evidence from the study by Coutinho [17], the study by Siqueira et al. [20], sought to evaluate the effectiveness of auriculotherapy in the control of chronic pain caused after CHIKV infection. Thirty-five individuals with chronic joint pain were followed during six sessions of auriculotherapy and the results of this study not only demonstrate the efficiency of this technique, but also clarify that the technique can be an adjuvant resource in the treatment of chronic joint pain in these patients, not just as a complementary treatment [20].

Corroborating the above, Tenório et al. [24] clarifies that fourteen physical therapy sessions with joint mobilizations, motor coordination training, analgesia and active and passive stretching and muscle strengthening exercises are important approaches in the treatment of post-Chikungunya fever patients. In their study, the results demonstrate that physiotherapeutic follow-up provided a decrease in pain intensity and an increase in the quality of life of patients with arthralgia after infection by arboviruses.

Reinforcing the results of Tenório et al. [24], the study by Almeida et al. [26] aimed to verify the influence of a multimodal physiotherapeutic approach on pain, quality of life, mobility and handgrip strength in patients with Chikungunya virus sequels. The sample consisted of twenty-one participants with persistent arthralgia after CHIKV infection.

The approach consisted of joint mobilizations, stretching, aerobic, active-resistance, active-free exercises and electrothermotherapeutic resources, totaling ten sessions. The results of this research indicate that a physiotherapeutic approach with electrothermotherapeutic and kinesiotherapeutic resources reduces pain, increases mobility, quality of life and handgrip strength in individuals with CHIKV sequels.

Strengths and limitations of the study

This study has some important limitations. The first concerns the variation in the age range of the participants in the included studies, ranging from 18 to 75 years. As there is a scarcity of experimental/intervention studies, it was not possible to develop a subgroup analysis in this systematic review, so information on specific groups (adults and elderly) could not be compared. The second limitation refers to the assessment of the risk of bias of the included studies, as almost half of the sample ranged from 45.4 to 63.3 (high and moderate risk of bias, respectively).

As for strengths, this is the first review that aims to carry out a survey on the contributions of musculoskeletal rehabilitation in the treatment of patients with sequelae after Chikungunya fever, in addition to specifically each type of intervention, outcomes and effects found.

Final considerations

The results of this study show the contributions of musculoskeletal functional rehabilitation in the treatment of patients with CHIKV sequelae. The most consolidated approaches in the literature used demonstrate that kinesiotherapy, associated or not with electrothermophototherapy, the pilates method and auriculotherapy, are useful resources in the treatment of these individuals, contributing significantly to pain relief, improved quality of life and functionality.

In this way, this study encourages the production of new research on a similar topic, in order to further emphasize the importance of the rehabilitative mechanisms that physiotherapy and other related professions use in patients with musculoskeletal manifestations after Chikungunya fever. Another point that needs greater exploratory effort is the early and accurate diagnosis of Chikungunya, since the signs and symptoms can be confused with other pathologies, such as rheumatoid arthritis, which can be considered a confusing fact in the treatment of sequels patients.

Data availability

The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.


  1. Brazilian Ministry of Health. Health Surveillance Secretariat. Health Surveillance General Coordination. Epidemiological Bulletin. Available in:

  2. Brasil P, Pereira JP, Raja GC, et al. Zika Virus infection in pregnant women in Rio de Janeiro. N Engl J Med. 2016;375(24):2321–34.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Burt FJ, Chen W, Miner JJ, Lenschow DJ, Merits A, Schnettler E, et al. Chikungunya virus: an update on the biology and pathogenesis of this emerging pathogen. Lancet Infect Dis [Internet] abril de. 2017;17(4):e107–17.

    Article  CAS  Google Scholar 

  4. Couderc T, Lecuit M. Chikungunya virus pathogenesis: from bedside to bench. Antiviral Res [Internet]. 2015;121:120–31.

    Article  CAS  PubMed  Google Scholar 

  5. Monitoramento dos casos de arboviroses até a semana. epidemiológica 18 de 2022 [Internet]. Available in:

  6. Dutra J. Prejuízos na qualidade de vida e funcionalidade de adultos cronicamente afetados pela febre chikungunya. [Dissertação]. [Faculdade de Ciências da Saúde do Trairi da Universidade Federal do Rio Grande do Norte]; 2019 [cited 2022 Oct 20]. p. 1–65. Available in:

  7. Drummond AD, Alves ED. Determinantes na funcionalidade de idosos da estratégia saúde da família – revisão integrativa. Tempus – Actas de Saúde Coletiva [Internet]. 2012;6(4):ág. 113–122. Available in:

  8. Nogueira SL, Ribeiro RCL, Rosado LEFPL, Franceschini SCC, Ribeiro AQ, Pereira ET. Fatores determinantes da capacidade funcional em idosos longevos. Braz. Journal Physical Therapy [Internet]. 2010; 14:322–9. Available in:

  9. Oliveira AS, Silva JG. Efeito de um programa de tratamento fisioterapêutico em paciente com poliartralgia persistente pós-febre de chikungunya. Relato de caso. Revista Dor [Internet]. 2017;18:370–3.

    Google Scholar 

  10. Ribeiro AMBM, Pimentel CM, Guerra ACCG, de Lima MR. O. Abordagem fisioterapêutica na fase tardia da chikungunya: um relato de caso. Rev Bras de Saúde Materno Infantil [Internet]. 2016;16:S51–6. Available in:

  11. Tricco AC, Lillie E, Zarin W, O’Brien KK, Colquhoun H, Levac D et al. PRISMA extension for scoping reviews (PRISMA-ScR): Checklist and explanation. Annals of Internal Medicine 2018 Sep 4;169(7):467–73. Available in:

  12. Systematic-review-register. - Systematic Review Register | Joanna Briggs Institute [Internet]. Available in:

  13. Ouzzani M, Hammady H, Fedorowicz Z, Elmagarmid A. Rayyan—a web and mobile app for systematic reviews. Syst Reviews. 2016;5(1):1–14.

    Article  Google Scholar 

  14. Moola S, Munn Z, Tufanaru C, Aromataris E, Sears K, Sfetcu R, Currie M, Lisy K, Qureshi R, Mattis P, Mu P. Chapter 7: Systematic reviews of etiology and risk. In: Aromataris E, Munn Z, editors. JBI Manual for Evidence Synthesis. JBI, 2020. Available in:

  15. Ribeiro AMBM, Pimentel CM, Guerra ACCG, de Lima MR. O. Abordagem fisioterapêutica na fase tardia da chikungunya: um relato de caso. Revista Brasileira de Saúde Materno Infantil [Internet]. 2016; 16:51–6. Available in:

  16. Silva-Filho E, Okano AH, Morya E, Albuquerque J, Cacho E, Unal G et al. Neuromodulation treats Chikungunya arthralgia: a randomized controlled trial. Sci Rep [Internet]. 2018;8(1). Available in:

  17. Coutinho BD. Efeitos da auriculoterapia na dor e limitação da mobilidade de indivíduos com febre chikungunya [Internet] [Tese]. [Universidade Federal de Minas Gerais]; 2018;5(2) 1–129. Available in:

  18. Oliveira BFA. O método pilates no tratamento das manifestações musculoesqueléticas crônicas da febre Chikungunya: um estudo randomizado [Internet] [Dissertação]. [Universidade Federal de Pernambuco]; 2018. p. 1–105. Available in:

  19. Neumann IL, de Oliveira DA, de Barros EL, da Santos S, de Oliveira G, Duarte LS. Resistance exercises improve physical function in chronic Chikungunya fever patients: a randomized controlled trial. Eur J Phys Rehabilitation Med [Internet]. 2021;57(4):620–9.

    Google Scholar 

  20. Siqueira DM. Efetividade da auriculoterapia na analgesia das dores crônicas causadas pela Chikungunya: ensaio clínico controlado e randomizado [Internet] [Trabalho de conclusão de curso]. [Fundação Oswaldo Cruz (FIOCRUZ Ceará)]; p. 1–70. Available in:

  21. Neumann IL. Efeito de um protocolo de exercícios resistidos progressivos sobre a funcionalidade de indivíduos com febre Chikungunya. [Dissertação] [Universidade Federal de Pernambuco]. 2019. Available in:

  22. Oliveira BFA, Carvalho PRC, Souza HAS, Santos RISB, da Silva FAX, Barros GWP, et al. Pilates method in the treatment of patients with Chikungunya fever: a randomized controlled trial. Clin Rehabilitation [Internet]. 2019;33(10):1614–24.

    Article  Google Scholar 

  23. Silva RN. Efeitos do exercício físico sobre o balanço oxidativo de células linfo mononucleares de pacientes com infecção crônica pelo vírus chikungunya. [Trabalho de Conclusão de Curso] [Universidade Federal de Pernambuco. Available in:

  24. Lima-tenório PM, Mesquita ICN, Oliveira AVR, Almeida MCE, Moraes SAS. Percepção de pacientes com artralgia pós arboviroses acerca do tratamento fisioterapêutico: relato de dois casos. Fisioterapia na Saúde Coletiva: Perspectivas para a Prática. Profissional. 2020;2(7):247–54.

    Google Scholar 

  25. Souza CG, Pegado R, Costa J, Morya E, Baptista AF, Unal G et al. Alternate sessions of transcranial direct current stimulation (tDCS) reduce chronic pain in women affected by chikungunya. A randomized clinical trial. Brain Stimulation. 2021 May;14(3):541–8. Available in:

  26. Almeida MCE, de Oliveira AVR, da Silva LF, Filho JDS, de Carvalho CAM, Jacob MM, et al. Programa fisioterapêutico multimodal na dor, qualidade de vida, mobilidade e força em indivíduos com sequela de Chikungunya. Cad Educ Saúde Fisiot. 2021;7(15):1–14.,persistente%20ap%C3%B3s%20infec%C3%A7%C3%A3o%20pelo%20CHIKV.

    Google Scholar 

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W.B.S and D. G. L. wrote the main manuscript text; C. S. T. R. prepared the figures and tables; S. G. G. F.; G. F. S. and A. C. C. M. reviewed the manuscript.

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Correspondence to Weslley Barbosa Sales.

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Sales, W.B., Leite, D.G., Truta Ramalho, C.S. et al. Contributions of musculoskeletal rehabilitation in patients after chikungunya fever: a systematic review. BMC Musculoskelet Disord 24, 347 (2023).

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