Skip to main content
Download PDF

Patients with combined pelvic and spinal injuries have worse clinical and operative outcomes than patients with isolated pelvic injuries analysis of the German Pelvic Registry

BMC Musculoskeletal Disorders volume 23, Article number: 251 (2022) Cite this article

Abstract

Background

Pelvic fractures are often associated with spine injury in polytrauma patients. This study aimed to determine whether concomitant spine injury influence the surgical outcome of pelvic fracture.

Methods

We performed a retrospective analysis of data of patients registered in the German Pelvic Registry between January 2003 and December 2017. Clinical characteristics, surgical parameters, and outcomes were compared between patients with isolated pelvic fracture (group A) and patients with pelvic fracture plus spine injury (group B). We also compared apart patients with isolated acetabular fracture (group C) versus patients with acetabular fracture plus spine injury (group D).

Results

Surgery for pelvic fracture was significantly more common in group B than in group A (38.3% vs. 36.6%; p = 0.0002), as also emergency pelvic stabilizations (9.5% vs. 6.7%; p < 0.0001). The mean time to emergency stabilization was longer in group B (137 ± 106 min vs. 113 ± 97 min; p < 0.0001), as well as the mean time until definitive stabilization of the pelvic fracture (7.3 ± 4 days vs. 5.4 ± 8.0 days; p = 0.147). The mean duration of treatment and the morbidity and mortality rates were all significantly higher in group B (p < 0.0001). Operation time was significantly shorter in group C than in group D (176 ± 81 min vs. 203 ± 119 min, p < 0.0001). Intraoperative blood loss was not significantly different between the two groups with acetabular injuries. Although preoperative acetabular fracture dislocation was slightly less common in group D, postoperative fracture dislocation was slightly more common. The distribution of Matta grades was significantly different between the two groups. Patients with isolated acetabular injuries were significantly less likely to have neurological deficit at discharge (94.5%; p < 0.0001). In-hospital complications were more common in patients with combined spine plus pelvic injuries (groups B and D) than in patients with isolated pelvic and acetabular injury (groups A and C).

Conclusions

Delaying definitive surgical treatment of pelvic fractures due to spinal cord injury appears to have a negative impact on the outcome of pelvic fractures, especially on the quality of reduction of acetabular fractures.

Peer Review reports

Introduction

In the case of a polytrauma patient, all possibly life-threatening injuries must be identified and treated as quickly as possible. Spinal cord injury should always be considered in patients with multiple injuries, even if no neurological deficit is present [1]. About 5% of polytrauma patients with pelvic and/or acetabular fracture will have spinal injury [29, 42]. Pelvic fractures as well as spine injuries occur generally in road traffic accidents or falls from heights, and the combination of both injuries can be life-threatening due to the force exerted to cause these injuries [18, 54]. Approximately 55% of spinal cord injuries occur in the cervical region, 15% in the thoracic region, 15% in the thoracolumbar junction, and 15% in the lumbosacral region. Up to 10% of patients with a cervical spine fracture will have a second, non-contiguous spine fracture [1, 13].

Due to the complex anatomy of the pelvis, pelvic fractures are often divided into pelvic ring fractures and acetabular fractures, as depending on the area of injury the surrounding tissues play an important role in concomitant injuries. Due to these characteristics and how scarcity these are, the treatment of such fractures depends on a certain degree of surgical expertise.

The most favorable time for osteosynthetic stabilization—performed to restore the pelvic ring stability and/or anatomic acetabular restoration—is determined by the gravity of adjuvant injuries and hemodynamic stability.

The stability of the pelvic ring is graded using the Tile classification, for which the integrity of the posterior pelvic ring dictates the stability grade of the entire pelvic ring [34]. Tile A lesions can be managed conservatively, but Tile B or C lesions will require surgical stabilization, usually by percutaneous insertion of sacroiliac screws for the posterior pelvic ring [10, 21]. In some cases, open reduction and internal fixation (ORIF) for the anterior pelvic ring may be required; however, an important requisite for ORIF is a hemodynamically stable patient. A supraacetabular external fixator is sometimes used for temporary or definitive treatment of the anterior pelvic ring injuries [43, 44].

In acetabular fractures, the essential objective of treatment is anatomical restoration of the joint line to avoid development of post-traumatic osteoarthritis.

ORIF is the gold standard treatment for displaced acetabular fractures. The quality of reduction achieved is recorded by the Matta grading score, which describes the postoperative step-off in the joint in Grade 1 (anatomical reconstruction: < 2 mm), Grade 2 (imperfect reduction: 2 – 3 mm), and Grade 3 (poor reduction > 3 mm) [3, 19, 28, 37, 48].

In patients with combined pelvic fracture and spine injury, treatment of the pelvic fracture is often delayed until the life-threatening spine injury has been dealt with, but whether this results in worse postoperative outcome of the pelvic fracture is not known [33, 41, 42]. The aim of this multicenter cohort study was to investigate how the postoperative outcome, follow-up and surgical treatment are influenced with a concomitant spine injury.

Our primary hypothesis was that an associated spine injury leads to delayed definitive surgical treatment of the pelvic fracture and that this unfavorably affects reduction quality of acetabular fractures.

Patients and methods

The Working Group Pelvis (AG Becken) of the German Society for Traumatology (Deutsche Gesellschaft für Unfallchirurgie) established a multicenter prospective registry in 1991 to improve the quality of care for pelvic and acetabular injuries. The Pelvic III Working Group prospectively records all pelvic and acetabular fractures in the participating hospitals (currently, 39 hospitals) [7, 8, 26]. The database is maintained since 2018 by the AUC GmbH (Academy of Trauma Surgery [Akademie der Unfallchirurgie]) with the sponsoring of the German Society for Traumatology and the Data used were collected in Bern, Switzerland by MEMdoc (medical Registries and Data Linkage). The German Pelvic Registry (GPR) has been approved by the Ethics Committee of the Chamber of Physicians of the Federal State of Saarland (No. 29/14). Inclusion criteria for the registry are pelvic ring and/or acetabular fracture and informed consent. Follow-up is determined for each patient individually conform to the duration of stationary treatment for the pelvic injury. The data of 16.359 patients with pelvic fractures were recorded correctly and entirely in the GPR from January 2003 to December 2017. These included 4.547 (27.8%) with acetabular fracture. We identified those with and without associated spine injury. In the GPR, spine injury is defined based on the criteria of the Injury Severity Scores (ISS) as an Abbreviated Injury Score (AIS Spine) > 0 for each spine segment (cervical, thoracic and lumbar) [22]. The data of the patients were extracted for retrospective analysis.

The Ethics Committee of the Eberhard-Karls-University in Tübingen, Germany, approved this cohort study (No. 968/2018BO2).

Evaluated parameters

The following parameters were analyzed:

  • Age

  • Gender

  • Injury Severity Score (ISS)

  • Hemoglobin level (Hb) at admission

  • Systolic blood pressure (SBP) at admission

  • Number of emergency stabilizations

  • Number of definitive surgical stabilizations

  • Time until emergency fracture stabilization (in minutes)

  • Time until definitive stabilization (in days)

  • Length of hospital stay (in days)

  • Overall complication rate (except osteosynthesis-associated complications)

  • Rate of osteosynthesis-associated complications

  • Mortality

The following complications were evaluated:

  • Hemorrhagic events

  • Thromboembolic events

  • Surgical site infection (superficial and deep)

  • Fracture-associated neurologic complications (preoperatively existing)

  • Iatrogenic neurologic complication

  • Pulmonary complications

  • Cardiac complications

  • Multiorgan failure

The following complications associated with osteosynthesis were evaluated:

  • Implant loosening

  • Implant failure

  • Secondary displacement of the fracture after definitive surgical fixation

To evaluate the quality of surgery in the acetabular fractures subgroup, the following surgical parameters were evaluated, focusing on the quality of the postoperative reposition:

  • Lenght of surgery (minutes)

  • Blood loss (milliliters)

  • Preoperative maximal fracture step-off (millimeters)

  • Postoperative maximal fracture step-off (millimeters)

  • Reduction quality based on Matta classification

Pre- and postoperative fracture step-offs were measured on pelvic radiographs (including oblique/iliac views) or CT scans by surgeons experienced in acetabular injuries. The maximum step-offs were recorded into the database.

Statistical analysis

Normally distributed data were expressed as means ± standard deviation, and non-normally distributed data as medians (range). Differences between group median values were analyzed using ANOVA with the Bonferroni and Tukey correction, as well as t-test and chi-square test. A p value < 0.05 was accepted as statistically significant. Data collection and tabulation were performed using Microsoft Excel.

Statistical analysis was performed using SPSS Statistics® (SPSS GmbH, Munich), with the help of Prof. Dr. Wolf-Dieter Heller (KIT Karlsruhe Institute of Technology).

Results

Of the 16.359 patients with pelvic fracture, 5. 927 (36.2%) had associated non-spinal injuries and so were excluded. Among the remaining patients, 8. 151 (49.8%, group A) had isolated pelvic ring and/or acetabular fracture and 2. 281 (13.6%, group B) had pelvic ring and/or acetabular fracture plus spine injury (Fig. 1).

Fig. 1
figure 1

Patient’s cohort from the GPR. Group A include patients with isolated pelvic fracture. Group B include patients with pelvic fracture plus spine injury. The remaining 5.927 patients were excluded from the study. Spine injury was defined as AIS (spine) > 0

Full size image

Of the 4. 547 patients with acetabular fractures, 2.558 (56.3%) had associated non-spinal injuries and so were excluded from the analysis. While 1.370 (30.1%; group C) had isolated acetabular fracture, 619 (13.6%; group D) had acetabular fracture plus spine injury (Fig. 2).

Fig. 2
figure 2

Patient’s cohort from the GPR. Group C include patients with isolated acetabular fracture. Group D include patients with combined acetabular fracture and spine injury. The remaining 11.812 patients were excluded from the study. Spine injury was defined as an AIS (Spine) > 0

Full size image

Basic data and fracture distribution

Mean age was significantly lower and ISS significantly higher in group B than in group A (p < 0.0001 for both). Pelvic ring fractures were the most common fracture type, being present in 73% of the total cohort. The dispersion of fracture types (isolated pelvic ring fracture, isolated acetabular fracture, or combined pelvic ring and acetabular fracture) was comparable in the two groups. Nevertheless, the proportion of unstable pelvic ring fractures (Tile B or C) was significantly lower in group A than in group B (55% vs. 92%, p < 0.0001; Table 1).

Table 1 Comparison of the fracture distribution and demographic data between patients with isolated pelvic fracture (group A) and combined spine/pelvic injury (group B). Values are shown as n (%) or as the mean ± standard deviation [range]; the data of ISS (Injury Severity Score) are the median values
Full size table

Concerning to the hemodynamic status of patients at the hospital admission, only data for 49 patients in group A and for 353 patients in group B were available and valid. Hemodynamic instability (Hb < 8.0 g/dL and/or SBP < 100 mm Hg) was significantly more common in group B patients than in group A patients (56% vs. 15%, p < 0.0001). Surgery for pelvic injury was performed more often in group B than in group A (38.3% vs. 36.6%; p = 0.0002), as also emergency pelvic stabilizations (9.5% vs. 6.7%; p = 0.176). The mean time until emergency stabilization was longer in group B (137 ± 106 min vs. 113 ± 97 min; p < 0.0001), as well as the mean time until definitive stabilization of the pelvic fracture (7.3 ± 4 days vs. 5.4 ± 8.0 days; p = 0.147). The mean duration of treatment and the morbidity and mortality were all significantly higher in group B than in group A (p < 0.0001; Table 2).

Table 2 Association of the clinical course between patients with isolated pelvic fracture (group A) and patients with combined spine/pelvic injury (group B). Values are shown as n (%), as a mean (μ) or as the mean ± standard deviation (range)
Full size table

Quality of surgery in acetabular fractures

Operation time was significantly shorter in group C than in group D (176 ± 81 min vs. 203 ± 119 min, p < 0.0001), but intraoperative blood loss was not significantly different between the two groups. Although preoperative fracture dislocation was slightly less common in group D, postoperative fracture dislocation was slightly more common. The distribution of Matta grades was significantly different between the two groups (Table 3).

Table 3 Association of clinical and surgical outcomes between patients with isolated acetabular fractures (group C) and patients with combined acetabular fracture and spinal injury. Data are presented as means ± standard deviation (range) or % (n)
Full size table

Spinal injury

Of the 2.224 patients in group B, 380 (17%) had isolated cervical spine injury, 680 (31%) had isolated thoracic spine injury, and 1.224 (52%) had isolated lumbar spine injury. While 84 patients had combined cervical and thoracic spine injuries, 103 had combined cervical and lumbar spine injuries, and 340 had combined thoracic and lumbar spine injuries. A total of 479 patients had injury of all three spinal segments (cervical, thoracic, and lumbar).

Neurological deficits and other complications

Respecting the neurological disability of the patients at admission within the groups, the patients with isolated acetabular injuries present a significantly lower neurological disability at discharge (94.5%; p < 0.0001). Compared to the other groups, it was a significantly higher neurological disability at discharge (group B: 843 vs. 862 patients; group C: 74 vs. 99 patients; group D: 270 vs. 280 patients; p < 0.0001). Complications were more common in patients with spine plus pelvic injuries (groups B and D) than in patients with isolated pelvic injury (groups A and C) (Table 4).

Table 4 Neurological disability and complications in patients with isolated pelvic injuries (group A), patients with a combined spine/pelvic injury (group B), patients with isolated acetabular fractures (group C), and patients with combined spine/acetabular injury (group D). Values are % (n)
Full size table

Discussion

In this study, we evaluated the operative and clinical outcomes between patients with pelvic fractures and patients with a combined spine/pelvic injuries in retrospectively collected cohort data from the GPR. We identified a significant association between pelvic fractures and spine injuries. Previous studies have found association between pelvic fractures and other injuries. A radiological study reported that 46% of patients with pelvic fractures had concurrent abdominal injury [31]. The pelvic and abdominal organs most likely to be injured in patients with pelvic fractures are the urogenital tract, major blood vessels, spleen, liver, and kidneys [14, 35, 49]. Meanwhile, extrapelvic injuries mostly to the thorax and head [2, 23, 45]. Although our study identified a significant relationship between pelvic fractures and spine injuries, it must be noted that this association was predominantly determined by the high frequency of lumbar spine injuries.

Literature review revealed similar satisfactory outcomes after both operative and non-operative management of spinal injuries, thus forming a comparative control group [9, 32, 38, 47]. However, the results are not so encouraging for pelvic fractures [12, 15, 16, 50, 51]. The treatment strategy for pelvic ring or acetabular fractures is decided by the degree of instability or dislocation, as well as the presence of other injuries. Although many pelvic fractures can be treated conservatively, when the fracture pattern involves the posterior pelvic ring and/or there is displacement of the acetabular fracture, ORIF is usually required. In the case that patient’s hemodynamic status allows a surgery and enough surgical experience is available, definitive treatment within the first 24 h after the accident guarantee good clinical and surgical results [11]. New operative techniques are on the rise, such as percutaneous fixation using the 3D fluoroscopic image-based navigation system that produces an intraoperative image comparable to that obtained with postoperative CT, thus allowing the best possible anatomical reduction to be achieved in a single surgical procedure [10]. The pelvic fracture that occurs with a high-energy trauma is often accompanied by spinal cord injury, which may delay osteosynthetic fixation of pelvic fractures.

A delay of more than 3 weeks has been shown to be associated with poor fracture reduction quality and surgical outcome [30].

According to the literature, the mortality rate in patients with pelvic fractures is in the range of 6%-13%, with the lower rates being reported in recent decades [4, 5, 20, 27]. Severe bleeding is the leading cause of death, whether caused by the fracture itself or by other related injuries. Application of standardized trauma management strategies (e.g. ATLS®, MARCH®) in prehospital care and emergency departments can significantly improve outcomes; these strategies involve early aggressive blood and clotting factors transfusion regimens, as well as non-invasive pelvic stabilization (e.g. pelvic binder) [6, 17, 24, 25, 46]. The treatment of pelvic fractures depends on the patient’s hemodynamic status and concomitant diseases. Unstable anterior pelvic ring fractures can be urgently stabilized with an external fixator and the posterior pelvic ring fractures with a pelvic C-clamp.

In the case of uncontrollable bleeding in hemodynamically stable patients, interventional radiological embolization is a viable option, but for hemodynamically unstable patients the gold standard is surgical preperitoneal pelvic packing until the patient’s status allows a revision surgery [36, 39].

A cooperative multidisciplinary approach is necessary to improve outcomes. Protocol-guided bleeding management, a decision-making algorithm, and the involvement of specialized orthopedic pelvic surgeons are essential [40]. Delay of fracture fixation because of concomitant injuries leads to increased morbidity, prolonged immobilization [52], and need for intensive unit care. Effective trauma care can ensure an improved outcome with less inpatient complications and briefer hospital stay, as well as a reduce in clinical resource consumption and costs [53].

In our cohort, patients with pelvic fracture plus spine injury were significantly younger; this correlates with the fact that patients with stable pelvic injury were considerably older (> 65 years of age; isolated pelvic injury 44.8% vs. associated pelvic/spine 8%) and patients with an unstable pelvic injury suffer an association of spine/pelvic injury thinkable of the necessary high-energy required trauma forces. In our cohort, patients with spine plus pelvic injuries had lower Hb levels and blood pressure values at admission. Due to the accompanying spine injuries, these patients were more likely to undergo emergency stabilizations (e.g., external fixation or pelvic C-clamp). Meanwhile, patients with isolated pelvic injury were more likely to receive definitive pelvic fixation. The time until emergency stabilization and the time until definitive pelvic stabilization were both significantly longer in patients with pelvic fracture plus spine injury. Even though, the time until definitive surgical treatment of pelvic fracture was delayed in patients with associated spine injury, the surgery was still performed within the recommended 5–8 days after the accident.

As hypothesized, the outcome was clearly worse when pelvic fracture was associated with spine injury. Patients with combined spine and pelvic injury had longer hospital stay, more blood transfusion within 12 h of admission, more inpatient complications, and higher overall morbidity, mortality, and neurological disability rates.

Limitations

The main strength of this study is the inclusion of a large sample number of patients from several centers. However, there are limitations. Besides the retrospective nature of the study, one of the main deficiencies is the fact that the German Pelvic Register does not have detailed data related to adjuvant spinal injuries, as it focuses on the treatment of pelvic fractures. To evaluate the effect of different spinal injuries on the quality of care of pelvic fractures, a prospective detailed study will be necessary.

Conclusion

Delaying definitive surgical treatment of pelvic fractures due to spinal cord injury appears to have a negative impact on the outcome of pelvic fractures, especially on the quality of reduction of acetabular fractures. Severe accompanying injuries increase morbidity and mortality risk thereby prolonging hospital stay. Interdisciplinary consultation and management are necessary to improve outcomes.

Availability of data and materials

The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.

Abbreviations

AUC:

Akademie für unfallchirurgie (Academy of trauma surgery)

AIS:

Abbreviated injury score

ATLS:

Advanced trauma life support

ANOVA:

Analysis of variance

CT:

Computer-tomography

GPR:

German pelvic registry

Hb:

Hemoglobin

ISS:

Injury severity score

KIT:

Karlsruhe institute of technology)

MARCH®:

Algorithm for massive hemorrhage, airway, respiration, circulation, head injury/hypothermia

ORIF:

Open reduction and internal fixation

SBP:

Systolic blood pressure

References

  1. Andrich S, Haastert B, Neuhaus E, et al. Epidemiology of Pelvic Fractures in Germany: Considerably High Incidence Rates among Older People. PLoS ONE. 2015;10(9):e0139078. https://doi.org/10.1371/journal.pone.0139078.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Ashkal A, Kong VY, Blodgett JM, et al. A review of blunt pelvic injuries at a major trauma centre in South Africa. S Afr J Surg. 2021;59(1):26a–26e.

    Article  CAS  Google Scholar 

  3. Badami DRN, Shetty DMS, Kumar DMA. Functional and radiological outcome of acetabular fractures and the factors affecting the outcome. Int J Orthop Sci. 2017;3(4e):314–20. https://doi.org/10.22271/ortho.2017.v3.i4e.42.

    Article  Google Scholar 

  4. Black SR, Sathy AK, Jo C, Wiley MR, Minei JP, Starr AJ. Improved Survival After Pelvic Fracture: 13-Year Experience at a Single Trauma Center Using a Multidisciplinary Institutional Protocol. J Orthop Trauma. 2016;30(1):22–8. https://doi.org/10.1097/BOT.0000000000000443.

    Article  PubMed  Google Scholar 

  5. Blackmore CC, Jurkovich GJ, Linnau KF, Cummings P, Hoffer EK, Rivara FP. Assessment of volume of hemorrhage and outcome from pelvic fracture. Arch Surg. 2003;138(5):504–9. https://doi.org/10.1001/archsurg.138.5.504.

    Article  PubMed  Google Scholar 

  6. Borgman MA, Spinella PC, Perkins JG, et al. The ratio of blood products transfused affects mortality in patients receiving massive transfusions at a combat support hospital. J Trauma. 2007;63(4):805–13. https://doi.org/10.1097/TA.0b013e3181271ba3.

    Article  PubMed  Google Scholar 

  7. Burkhardt M, Nienaber U, Krause J, et al. Das komplexe Beckentrauma: Matching des Beckenregisters DGU mit dem TraumaRegister DGU®. Unfallchirurg. 2015;118(11):957–62. https://doi.org/10.1007/s00113-014-2565-8.

    Article  CAS  PubMed  Google Scholar 

  8. Burkhardt M, Nienaber U, Holstein JH, et al. Trauma registry record linkage: Methodological approach to benefit from complementary data using the example of the German Pelvic Injury Register and the TraumaRegister DGU®. BMC Med Res Methodol. 2013;13(1):1. https://doi.org/10.1186/1471-2288-13-30.

    Article  Google Scholar 

  9. Cantor JB, Lebwoh NH, Garvey T, Eismont FJ. Nonoperative management of stable thoracolumbar burst fractures with early ambulation and bracing. Spine (Phila Pa 1976). 1993;18(8):971–6.

    Article  CAS  Google Scholar 

  10. Ciolli G, Caviglia D, Vitiello C, et al. Navigated percutaneous screw fixation of the pelvis with o-arm 2: Two years’ experience. Med Glas. 2021;18(1):1–7. https://doi.org/10.17392/1326-21.

    Article  Google Scholar 

  11. Coccolini F, Stahel PF, Montori G, et al. Pelvic trauma: WSES classification and guidelines. World J Emerg Surg. 2017;12:5. https://doi.org/10.1186/s13017-017-0117-6.

    Article  PubMed  PubMed Central  Google Scholar 

  12. Cole JD, Blum DA, Ansel LJ. Outcome after fixation of unstable posterior pelvic ring injuries. Clin Orthop Relat Res. 1996;329:160–79. https://doi.org/10.1097/00003086-199608000-00020.

    Article  Google Scholar 

  13. Cooper C, Dunham CM, Rodriguez A. Falls and major injuries are risk factors for thoracolumbar fractures: cognitive impairment and multiple injuries impede the detection of back pain and tenderness. J Trauma. 1995;38(5):692–6. https://doi.org/10.1097/00005373-199505000-00003.

    Article  CAS  PubMed  Google Scholar 

  14. Culemann U, Scola A, Tosounidis G, Pohlemann T, Gebhard F. Concept for treatment of pelvic ring injuries in elderly patients. A challenge. Unfallchirurg. 2010;113(4):258–71. https://doi.org/10.1007/s00113-010-1762-3.

    Article  CAS  PubMed  Google Scholar 

  15. Draijer F, Egbers HJ, Havemann D. Quality of life after pelvic ring injuries: follow-up results of a prospective study. Arch Orthop Trauma Surg. 1997;116(1–2):22–6. https://doi.org/10.1007/BF00434095.

    Article  CAS  PubMed  Google Scholar 

  16. Dujardin FH, Hossenbaccus M, Duparc F, Biga N, Thomine JM. Long-term functional prognosis of posterior injuries in high-energy pelvic disruption. J Orthop Trauma. 1998;12(3):141–5. https://doi.org/10.1097/00005131-199803000-00001.

    Article  Google Scholar 

  17. Eastridge BJ, Starr A, Minei JP, O’Keefe GE, Scalea TM. The importance of fracture pattern in guiding therapeutic decision-making in patients with hemorrhagic shock and pelvic ring disruptions. J Trauma. 2002;53(3):441–6. https://doi.org/10.1097/00005373-200209000-00009.

    Article  Google Scholar 

  18. Fernandez-de Thomas RJ, De Jesus O. Thoracolumbar Spine Fracture. 2021 Aug 30. In: StatPearls (Internet). Treasure Island: StatPearls Publishing; 2022.

  19. Gänsslen A, Oestern HJ. Azetabulumfrakturen. Chirurg. 2011;82(12):1133–50. https://doi.org/10.1007/s00104-011-2135-3.

    Article  PubMed  Google Scholar 

  20. Gaski IA, Barckman J, Naess PA, et al. Reduced need for extraperitoneal pelvic packing for severe pelvic fractures is associated with improved resuscitation strategies. J Trauma Acute Care Surg. 2016;81(4):644–51. https://doi.org/10.1097/TA.0000000000001139.

    Article  PubMed  Google Scholar 

  21. Giráldez-Sánchez MA, Lázaro-Gonzálvez Á, Martínez-Reina J, et al. Percutaneous iliosacral fixation in external rotational pelvic fractures A biomechanical analysis. Injury. 2015;46(2):327–32. https://doi.org/10.1016/j.injury.2014.10.058.

    Article  PubMed  Google Scholar 

  22. Greenspan L, McLellan B, Greig H. AIS and ISS - A scoring chart.pdf. J Trauma. 1985;25(1):60–4.

    Article  CAS  Google Scholar 

  23. Gustavo Parreira J, Coimbra R, Rasslan S, Oliveira A, Fregoneze M, Mercadante M. The role of associated injuries on outcome of blunt trauma patients sustaining pelvic fractures. Injury. 2000;31(9):677–82. https://doi.org/10.1016/s0020-1383(00)00074-7.

    Article  CAS  PubMed  Google Scholar 

  24. Holcomb JB, Tilley BC, Baraniuk S, et al. Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma: the PROPPR randomized clinical trial. JAMA. 2015;313(5):471–82. https://doi.org/10.1001/jama.2015.12.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  25. Holcomb JB, Wade CE, Michalek JE, et al. Increased plasma and platelet to red blood cell ratios improves outcome in 466 massively transfused civilian trauma patients. Ann Surg. 2008;248(3):447–58. https://doi.org/10.1097/SLA.0b013e318185a9ad.

    Article  PubMed  Google Scholar 

  26. Holstein JH, Stuby FM, Herath SC, Culemann U, Aghayev E, Pohlemann T. Einfluss des Beckenregisters der DGU auf die Versorgung von Beckenringfrakturen. Unfallchirurg. 2016;119(6):475–81. https://doi.org/10.1007/s00113-016-0168-2.

    Article  CAS  PubMed  Google Scholar 

  27. Holstein JH, Culemann U, Pohlemann T. What are predictors of mortality in patients with pelvic fractures? Clin Orthop Relat Res. 2012;470(8):2090–7. https://doi.org/10.1007/s11999-012-2276-9.

    Article  PubMed  PubMed Central  Google Scholar 

  28. Iqbal F, Taufiq I, Kazim M, Najjad R, Khan N, Zia O Bin. Hp-28–217. 2016;28(4):217–224.

  29. VandenBerg J, Cullison K, Fowler SA, Parsons MS, McAndrew CM, Carpenter CR. Blunt Thoracolumbar-Spine Trauma Evaluation in the Emergency Department: A Meta-Analysis of Diagnostic Accuracy for History, Physical Examination, and Imaging. J Emerg Med. 2019;56(2):153–65. https://doi.org/10.1016/j.jemermed.2018.10.032.

    Article  PubMed  Google Scholar 

  30. Katsoulis E, Giannoudis PV. Impact of timing of pelvic fixation on functional outcome. Injury. 2006;37(12):1133–42. https://doi.org/10.1016/j.injury.2006.07.017.

    Article  PubMed  Google Scholar 

  31. Killeen KL, DeMeo JH. CT detection of serious internal and skeletal injuries in patients with pelvic fractures. Acad Radiol. 1999;6(4):224–8. https://doi.org/10.1016/S1076-6332(99)80209-8.

    Article  CAS  PubMed  Google Scholar 

  32. Knight RQ, Stornelli DP, Chan DP, Devanny JR, Jackson KV. Comparison of operative versus nonoperative treatment of lumbar burst fractures. Clin Orthop Relat Res. 1993;293:112–21.

    Article  Google Scholar 

  33. Kumar R, Lim J, Mekary RA, et al. Traumatic Spinal Injury: Global Epidemiology and Worldwide Volume. World Neurosurg. 2018;113:e345–63. https://doi.org/10.1016/j.wneu.2018.02.033.

    Article  PubMed  Google Scholar 

  34. Lee C-H, Hsu C-C, Huang P-Y. Biomechanical study of different fixation techniques for the treatment of sacroiliac joint injuries using finite element analyses and biomechanical tests. Comput Biol Med. 2017;87:250–7. https://doi.org/10.1016/j.compbiomed.2017.06.007.

    Article  PubMed  Google Scholar 

  35. Leenen LPH. Pelvic Fractures: Soft Tissue Trauma. Eur J trauma Emerg Surg Off Publ Eur Trauma Soc. 2010;36(2):117–23. https://doi.org/10.1007/s00068-010-1038-0.

    Article  Google Scholar 

  36. Marzi I, Lustenberger T. Management of Bleeding Pelvic Fractures. Scand J Surg SJS Off organ Finnish Surg Soc Scand Surg Soc. 2014;103(2):104–11. https://doi.org/10.1177/1457496914525604.

    Article  CAS  Google Scholar 

  37. Matta JM. Fractures of the acetabulum: Accuracy of reduction and clinical results in patients managed operatively within three weeks after the injury. J Bone Jt Surg - Ser A. 1996;78(11):1632–45. https://doi.org/10.1055/s-0030-1267077.

    Article  CAS  Google Scholar 

  38. Mumford J, Weinstein JN, Spratt KF, Goel VK. Thoracolumbar burst fractures. The clinical efficacy and outcome of nonoperative management. Spine (Phila Pa 1976). 1993;18(8):955–70.

    Article  CAS  Google Scholar 

  39. Niola R, Pinto A, Sparano A, Ignarra R, Romano L, Maglione F. Arterial bleeding in pelvic trauma: priorities in angiographic embolization. Curr Probl Diagn Radiol. 2012;41(3):93–101. https://doi.org/10.1067/j.cpradiol.2011.07.008.

    Article  PubMed  Google Scholar 

  40. Perkins ZB, Maytham GD, Koers L, Bates P, Brohi K, Tai NRM. Impact on outcome of a targeted performance improvement programme in haemodynamically unstable patients with a pelvic fracture. Bone Joint J. 2014;96-B(8):1090–7. https://doi.org/10.1302/0301-620X.96B8.33383.

    Article  CAS  PubMed  Google Scholar 

  41. Phruetthiphat O-A, Willey M, Karam MD, Gao Y, Westerlind BO, Marsh JL. Comparison of Outcomes and Complications of Isolated Acetabular Fractures and Acetabular Fractures With Associated Injuries. J Orthop Trauma. 2017;31(1):31–6. https://doi.org/10.1097/BOT.0000000000000720.

    Article  PubMed  Google Scholar 

  42. Pouw MH, Deunk J, Brink M, et al. Is a pelvic fracture a predictor for thoracolumbar spine fractures after blunt trauma? J Trauma - Inj Infect Crit Care. 2009;67(5):1027–32. https://doi.org/10.1097/TA.0b013e31818cb261.

    Article  Google Scholar 

  43. Rommens PM, Dietz S-O, Ossendorf C, Pairon P, Wagner D, Hofmann A. Fragility fractures of the pelvis: should they be fixed? Acta Chir Orthop Traumatol Cech. 2015;82(2):101–12.

    CAS  PubMed  Google Scholar 

  44. Rommens PM, Wagner D, Hofmann A. Minimal Invasive Surgical Treatment of Fragility Fractures of the Pelvis. Chirurgia (Bucur). 2017;112(5):524–37. https://doi.org/10.21614/chirurgia.112.5.524.

    Article  Google Scholar 

  45. Saydam M, Şahin M, Yilmaz KB, et al. Correlation of pelvic fractures and associated injuries: An analysis of 471 pelvic trauma patients. Ulus travma ve acil cerrahi Derg. 2019;25(5):489–96. https://doi.org/10.5505/tjtes.2018.72505.

    Article  Google Scholar 

  46. Schweigkofler U, Wohlrath B, Trentsch H, et al. Diagnostics and early treatment in prehospital and emergency-room phase in suspicious pelvic ring fractures. Eur J trauma Emerg Surg Off Publ Eur Trauma Soc. 2018;44(5):747–52. https://doi.org/10.1007/s00068-017-0860-0.

    Article  Google Scholar 

  47. Shen WJ, Shen YS. Nonsurgical treatment of three-column thoracolumbar junction burst fractures without neurologic deficit. Spine (Phila Pa 1976). 1999;24(4):412–5. https://doi.org/10.1097/00007632-199902150-00024.

    Article  CAS  Google Scholar 

  48. Shi HF, Xiong J, Chen YX, Wang JF, Wang YH. Radiographic analysis of the restoration of hip joint center following open reduction and internal fixation of acetabular fractures: A retrospective cohort study. BMC Musculoskelet Disord. 2014;15(1):277. https://doi.org/10.1186/1471-2474-15-277.

    Article  PubMed  PubMed Central  Google Scholar 

  49. Siegmeth A, Müllner T, Kukla C, Vécsei V. Associated injuries in severe pelvic trauma. Unfallchirurg. 2000;103(7):572–81. https://doi.org/10.1007/s001130050585.

    Article  CAS  PubMed  Google Scholar 

  50. Tee SS, Hyzan Y, Razak M. Functional outcome of open reduction and internal fixation of pelvic ring injuries. Med J Malaysia. 2000;55(Suppl C):49–58.

    PubMed  Google Scholar 

  51. Tornetta P 3rd, Matta JM. Outcome of operatively treated unstable posterior pelvic ring disruptions. Clin Orthop Relat Res. 1996;329:186–93. https://doi.org/10.1097/00003086-199608000-00022.

    Article  Google Scholar 

  52. Vallier HA, Cureton BA, Ekstein C, Oldenburg FP, Wilber JH. Early definitive stabilization of unstable pelvis and acetabulum fractures reduces morbidity. J Trauma. 2010;69(3):677–84. https://doi.org/10.1097/TA.0b013e3181e50914.

    Article  PubMed  Google Scholar 

  53. Vallier HA, Dolenc AJ, Moore TA. Early Appropriate Care: A Protocol to Standardize Resuscitation Assessment and to Expedite Fracture Care Reduces Hospital Stay and Enhances Revenue. J Orthop Trauma. 2016;30(6):306–11. https://doi.org/10.1097/BOT.0000000000000524.

    Article  PubMed  Google Scholar 

  54. VandenBerg J, Cullison K, Fowler SA, Parsons MS, McAndrew CM, Carpenter CR. Blunt Thoracolumbar-Spine Trauma Evaluation in the Emergency Department: A Meta-Analysis of Diagnostic Accuracy for History, Physical Examination, and Imaging. J Emerg Med. 2019;56(2):153–65. https://doi.org/10.1016/j.jemermed.2018.10.032.

    Article  PubMed  Google Scholar 

Download references

Acknowledgements

We sincerely thank Mr. Prof. Dr. Wolf-Dieter Heller for the statistical analysis (Karlsruhe Institute of Technology, Karlsruhe, Germany)

Funding

Not applicable.

Author information

Authors and Affiliations

  1. ARCUS Sportklinik, Rastatterstraße 17–19, 72175, Pforzheim, Germany

    Luis Navas, Natalie Mengis, Alexander Zimmerer, Jules-Nikolaus Rippke & Sebastian Schmidt

  2. Orthopädische Klinik PaulinenhilfeDiakonieklinikum Stuttgart, Rosenbergstraße 38, 70176, Stuttgart, Deutschland

    Luis Navas

  3. Department of Orthopedics and Orthopedic Surgery, University Medicine Greifswald, Ferdinand-Sauerbruch-Straße, 17475, Greifswald, Germany

    Alexander Zimmerer

  4. Bezirkskrankenhaus St. Johann in Tirol, Bahnhofstrasse 14, 6380, St. Johann, Tirol, Austria

    Alexander Brunner & Moritz Wagner

  5. Department of Orthopedics, Trauma and Plastic Surgery, University of Leipzig, Liebigstraße 20, 04103, Leipzig, Germany

    Andreas Höch

  6. Department for Traumatology and Reconstructive Surgery, BG Trauma Center, University of Tübingen, Schnarrenbergstraße 95, 72,076, Tübingen, Germany

    Tina Histing, Steven C. Herath, Markus A. Küper & Benjamin Ulmar

Authors
  1. Luis Navas
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Natalie Mengis
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Alexander Zimmerer
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Jules-Nikolaus Rippke
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Sebastian Schmidt
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Alexander Brunner
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Moritz Wagner
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Andreas Höch
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Tina Histing
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. Steven C. Herath
    View author publications

    You can also search for this author in PubMed Google Scholar

  11. Markus A. Küper
    View author publications

    You can also search for this author in PubMed Google Scholar

  12. Benjamin Ulmar
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

LN, NM, MAK, TH, and BU designed the study from an orthopedic and trauma surgeon’s point of view. LN, NM, JNR and BU acquired the data from the German Pelvic Registry. LN, NM, and BU did the data analysis. All authors interpreted the data, revised the manuscript regarding scientific input, and approved the submitted final version.

Corresponding author

Correspondence to Benjamin Ulmar.

Ethics declarations

Ethics approval and consent to participate

The patients gave written informed consent for participation in the GPR. The study was conducted according to the guidelines of the Declaration of Helsinki. The Ethics Committee of the Chamber of Physicians of the Federal State of Saarland approved the GPR (No. 29/14). The Ethics Committee of the Eberhard-Karls-University in Tübingen, Germany, approved this retrospective cohort study (No. 968/2018BO2).

Consent for publication

Consent for publication was part of the written informed consent the patients gave for their participation in the GPR.

Competing interests

Not applicable.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Navas, L., Mengis, N., Zimmerer, A. et al. Patients with combined pelvic and spinal injuries have worse clinical and operative outcomes than patients with isolated pelvic injuries analysis of the German Pelvic Registry. BMC Musculoskelet Disord 23, 251 (2022). https://doi.org/10.1186/s12891-022-05193-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1186/s12891-022-05193-0

Keywords

  • Pelvic trauma
  • Pelvic ring fracture
  • Acetabular fracture
  • Spine injury
  • Postoperative reduction
  • Mata grading

BMC Musculoskeletal Disorders

ISSN: 1471-2474

Contact us