Arden N, Nevitt MC. Osteoarthritis: epidemiology. Best Pract Res Clin Rheumatol. 2006;20:3–25.
Article
Google Scholar
Rai MF, Duan X, Quirk JD, Holguin N, Schmidt EJ, Chinzei N, Silva MJ, Sandell LJ. Post-traumatic osteoarthritis in mice following mechanical injury to the synovial joint. Sci Rep. 2017;7:45223.
Article
CAS
Google Scholar
Goldring MB, Culley KL, Otero M. Pathogenesis of osteoarthritis in General. Cham, Switzerland: Springer; 2017.
Buckwalter JA, Lane NE. Athletics and osteoarthritis. Am J Sports Med. 1997;25:873–81.
Article
CAS
Google Scholar
Ficklin T, Thomas G, Barthel JC, Asanbaeva A, Thonar EJ, Masuda K, Chen AC, Sah RL, Davol A, Klisch SM. Articular cartilage mechanical and biochemical property relations before and after in vitro growth. J Biomech. 2007;40:3607–14.
Article
Google Scholar
Wilson W, van Burken C, van Donkelaar C, Buma P, van Rietbergen B, Huiskes R. Causes of mechanically induced collagen damage in articular cartilage. J Orthop Res. 2006;24:220–8.
Article
Google Scholar
Ashwell MS, O'Nan AT, Gonda MG, Mente PL. Gene expression profiling of chondrocytes from a porcine impact injury model. Osteoarthr Cartil. 2008;16:936–46.
Article
CAS
Google Scholar
Aigner T, Dudhia J. Genomics of osteoarthritis. Curr Opin Rheumatol. 2003;15:634–40.
Article
CAS
Google Scholar
Salzmann GM, Nuernberger B, Schmitz P, Anton M, Stoddart MJ, Grad S, Milz S, Tischer T, Vogt S, Gansbacher B. Physicobiochemical synergism through gene therapy and functional tissue engineering for in vitro chondrogenesis. Tissue Eng Part A. 2009;15:2513–24.
Article
CAS
Google Scholar
Aigner T, Zien A, Hanisch D, Zimmer R. Gene expression in chondrocytes assessed with use of microarrays. J Bone Jt Surg. 2003;85:117–23.
Article
Google Scholar
Kapitanov GI, Ayati BP, Martin JA. Modeling the effect of blunt impact on mitochondrial function in cartilage: implications for development of osteoarthritis. PeerJ. 2017;5:e3468.
Article
Google Scholar
Maerz T, Newton MD, Kurdziel MD, Altman P, Anderson K, Matthew HW, Baker KC. Articular cartilage degeneration following anterior cruciate ligament injury: a comparison of surgical transection and noninvasive rupture as preclinical models of post-traumatic osteoarthritis. Osteoarthr Cartil. 2016;24(11):1918–27.
Article
CAS
Google Scholar
Wiegant K, Intema F, Van Roermund PM, Barten-van Rijbroek AD, Doornebal A, Hazewinkel HA, Lafeber FP, Mastbergen SC. Evidence of cartilage repair by joint distraction in a canine model of osteoarthritis. Arthritis Rheumatol. 2015;67(2):465–74.
Article
Google Scholar
Martin JA, Anderson DD, Goetz JE, Fredericks D, Pedersen DR, Ayati BP, Marsh JL, Buckwalter JA. Complementary models of post-traumatic osteoarthritis reveal cellular responses to contact stress that damage articular cartilage and present targets for intervention. J Orthop Res. 2017;35(3):515.
Article
Google Scholar
Zhao Y, Liu X, Mo D, Chen Q, Chen Y. Analysis of reasons for sow culling and seasonal effects on reproductive disorders in southern China. Anim Reprod Sci. 2015;159:191–7.
Article
Google Scholar
Crenshaw TD. Arthritis or OCD-identification and prevention. Adv Pork Prod. 2006;17:199.
Google Scholar
Kirk RK, Svensmark B, Ellegaard LP, Jensen HE. Locomotive disorders associated with sow mortality in Danish pig herds. Transbound Emerg Dis. 2005;52:423–8.
CAS
Google Scholar
Stavrakakis S, Guy JH, Syranidis I, Johnson GR, Edwards SA. Pre-clinical and clinical walking kinematics in female breeding pigs with lameness: a nested case-control cohort study. Vet J. 2015;205:38–43.
Article
CAS
Google Scholar
Muirhead MR, Alexander TJL. Chapter 9: Managing health in the weaner, grower and finishing periods. In: Carr J, editor. Managing Pig Heath: A Reference for the Farm. 2nd ed; 2013. p. 388.
Google Scholar
Lee KB, Hui JH, Song IC, Ardany L, Lee EH. Injectable mesenchymal stem cell therapy for large cartilage defects—a porcine model. Stem Cells. 2007;25(11):2964–71.
Article
Google Scholar
Gelse K, Mühle C, Franke O, Park J, Jehle M, Durst K, Göken M, Hennig F, Mark KV, Schneider H. Cell-based resurfacing of large cartilage defects: long-term evaluation of grafts from autologous transgene-activated periosteal cells in a porcine model of osteoarthritis. Arthritis & Rheumatism: official. J Am Coll Rheumatol. 2008;58(2):475–88.
CAS
Google Scholar
Goldring MB. The role of cytokines as inflammatory mediators in osteoarthritis: lessons from animal models. Connect Tissue Res. 1999;40(1):1–1.
Article
CAS
Google Scholar
Sieker JT, Proffen BL, Waller KA, Chin KE, Karamchedu NP, Akelman MR, Perrone GS, Kiapour AM, Konrad J, Murray MM, Fleming BC. Transcriptional profiling of articular cartilage in a porcine model of early post-traumatic osteoarthritis. J Orthop Res. 2018;36(1):318–29.
CAS
PubMed
Google Scholar
McCulloch RS, Ashwell MS, Maltecca C, O'Nan AT, Mente PL. Progression of gene expression changes following a mechanical injury to articular cartilage as a model of early stage osteoarthritis. Arthritis. 2014:371426.
McCulloch RS, Ashwell MS, T O’Nan A, Mente PL. Identification of stable normalization genes for quantitative real-time PCR in porcine articular cartilage. J Anim Sci Biotechnol 2012;3:36.
Steibel JP, Poletto R, Coussens PM, Rosa GJ. A powerful and flexible linear mixed model framework for the analysis of relative quantification RT-PCR data. Genomics. 2009;94:146–52.
Article
CAS
Google Scholar
Reiner A, Yekutieli D, Benjamini Y. Identifying differentially expressed genes using false discovery rate controlling procedures. Bioinformatics. 2003;19:368–75.
Article
CAS
Google Scholar
Xu Y, Barter MJ, Swan DC, Rankin KS, Rowan AD, Santibanez-Koref M, Loughlin J, Young DA. Identification of the pathogenic pathways in osteoarthritic hip cartilage: commonality and discord between hip and knee OA. Osteoarthr Cartil. 2012;20:1029–38.
Article
CAS
Google Scholar
Peffers MJ, Liu X, Clegg PD. Transcriptomic signatures in cartilage ageing. Arthritis Res Ther. 2013;15:R98.
Article
Google Scholar
Fitzgerald JB, Jin M, Dean D, Wood DJ, Zheng MH, Grodzinsky AJ. Mechanical compression of cartilage explants induces multiple time-dependent gene expression patterns and involves intracellular calcium and cyclic AMP. J Biol Chem. 2004;279:19502–11.
Article
CAS
Google Scholar
Van der Kraan PM, Van den Berg WB. Chondrocyte hypertrophy and osteoarthritis: role in initiation and progression of cartilage degeneration? Osteoarthr Cartil. 2012;20:223–32.
Article
Google Scholar
Swingler TE, Waters JG, Davidson RK, Pennington CJ, Puente XS, Darrah C, Cooper A, Donell ST, Guile GR, Wang W. Degradome expression profiling in human articular cartilage. Arthritis Res Ther. 2009;11:R96.
Article
Google Scholar
Kim HA, Lee YJ, Seong S, Choe KW, Song YW. Apoptotic chondrocyte death in human osteoarthritis. J Rheumatol. 2000;27:455–62.
CAS
PubMed
Google Scholar