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  1. The aim of this analysis was to determine the relative influence of disease and non-disease factors on areal bone mineral density (BMDa) in a primary care based cohort of women with inflammatory polyarthritis.

    Authors: Stephen R Pye, Tarnya Marshall, Karl Gaffney, Alan J Silman, Deborah PM Symmons and Terence W O'Neill
    Citation: BMC Musculoskeletal Disorders 2010 11:106
  2. Transforming growth factor-β (TGF-β) and bone morphogenetic proteins (BMPs) utilize parallel and related signaling pathways, however the interaction between these pathways in bone remains unclear. TGF-β inhibi...

    Authors: Aaron Schindeler, Alyson Morse, Lauren Peacock, Kathy Mikulec, Nicole YC Yu, Renjing Liu, Sandy Kijumnuayporn, Michelle M McDonald, Paul A Baldock, Andrew J Ruys and David G Little
    Citation: BMC Musculoskeletal Disorders 2010 11:105
  3. Numerous transcription factors are involved in the establishment and maintenance of the osteoblastic phenotype, such as Runx2, osterix and Dlx5. The transcription factor retinoblastoma binding protein-1 (RBP1)...

    Authors: David G Monroe, John R Hawse, Malayannan Subramaniam and Thomas C Spelsberg
    Citation: BMC Musculoskeletal Disorders 2010 11:104
  4. Gel-type autologous chondrocyte (Chondron™) implantations have been used for several years without using periosteum or membrane. This study involves evaluations of the clinical results of Chondron™ at many cli...

    Authors: Nam-Yong Choi, Byoung-Woo Kim, Woo-Jin Yeo, Haeng-Boo Kim, Dong-Sam Suh, Jin-Soo Kim, Yoon-Sik Kim, Yong-Ho Seo, Jea-Yeong Cho, Chung-Woo Chun, Hyun-Shin Park, Asode Ananthram Shetty and Seok-Jung Kim
    Citation: BMC Musculoskeletal Disorders 2010 11:103
  5. The purpose of our study was to analyze the clinical and radiological long-term outcomes of surgically treated traumatic knee dislocations and determine prognostic factors for outcome.

    Authors: Michael T Hirschmann, Nadia Zimmermann, Thomas Rychen, Christian Candrian, Damir Hudetz, Lukas G Lorez, Felix Amsler, Werner Müller and Niklaus F Friederich
    Citation: BMC Musculoskeletal Disorders 2010 11:102
  6. There are multiple revision implant systems currently available for socket revision in revision total hip arthroplasty. Up until now, not all of these systems have been followed up with regards to their long-t...

    Authors: Stefan Lakemeier, Guenter Aurand, Nina Timmesfeld, Thomas J Heyse, Susanne Fuchs-Winkelmann and Markus D Schofer
    Citation: BMC Musculoskeletal Disorders 2010 11:101
  7. Decompressive laminotomy is the standard surgical procedure in the treatment of patients with canal stenosis related intermittent neurogenic claudication. New techniques, such as interspinous process implants,...

    Authors: Wouter A Moojen, Mark P Arts, Ronald Brand, Bart W Koes and Wilco C Peul
    Citation: BMC Musculoskeletal Disorders 2010 11:100
  8. Arm, shoulder and neck symptoms are very prevalent among computer workers. In an attempt to reduce these symptoms, a large occupational health service in the Netherlands developed a preventive programme on exp...

    Authors: Erwin M Speklé, Marco JM Hoozemans, Birgitte M Blatter, Judith Heinrich, Allard J van der Beek, Dirk L Knol, Paulien M Bongers and Jaap H van Dieën
    Citation: BMC Musculoskeletal Disorders 2010 11:99
  9. Rheumatic diseases are a major health and financial burden for societies. The prevalence of rheumatic diseases may change over time, and therefore, we sought to estimate the prevalence of rheumatic diseases in...

    Authors: Ioannis Anagnostopoulos, Elias Zinzaras, Ioannis Alexiou, Aphrodite A Papathanasiou, Evangelos Davas, Athanasios Koutroumpas, Georgia Barouta and Lazaros I Sakkas
    Citation: BMC Musculoskeletal Disorders 2010 11:98
  10. Fractures of the proximal humerus are associated with a profound temporary and sometimes permanent, impairment of function and quality of life. The treatment of comminuted fractures of the proximal humerus lik...

    Authors: Dennis Den Hartog, Esther MM Van Lieshout, Wim E Tuinebreijer, Suzanne Polinder, Ed F Van Beeck, Roelf S Breederveld, Maarten WGA Bronkhorst, Jan Peter Eerenberg, Steven Rhemrev, W Herbert Roerdink, Gerrit Schraa, Harm M Van der Vis, Thom PH Van Thiel, Peter Patka, Stefaan Nijs and Niels WL Schep
    Citation: BMC Musculoskeletal Disorders 2010 11:97
  11. Allograft bone used in joint replacement surgery can additionally serve as a carrier for antibiotics and serve as a prophylaxis against infections. However, in vitro dose-response curves for bone chips impregnate...

    Authors: Nina MC Mathijssen, Pieter LC Petit, Peter Pilot, B Wim Schreurs, Pieter Buma and Rolf M Bloem
    Citation: BMC Musculoskeletal Disorders 2010 11:96
  12. Angle-stable locking plates have improved the surgical management of fractures. However, locking implants are costly and removal can be difficult. The aim of this in vitro study was to evaluate the biomechanic...

    Authors: Markus Windolf, Kajetan Klos, Dirk Wähnert, Bas van der Pol, Roman Radtke, Karsten Schwieger and Roland P Jakob
    Citation: BMC Musculoskeletal Disorders 2010 11:95
  13. Hand strength is an important independent surrogate parameter to assess outcome and risk of morbidity and mortality. This study aimed to determine the predictive power of cofactors and to predict population-ba...

    Authors: Felix Angst, Susann Drerup, Stephan Werle, Daniel B Herren, Beat R Simmen and Jörg Goldhahn
    Citation: BMC Musculoskeletal Disorders 2010 11:94
  14. Scoliosis is present in 3-5% of the children in the adolescent age group, with a higher incidence in females. Treatment of adolescent idiopathic scoliosis is mainly dependent on the progression of the scolioti...

    Authors: Iris Busscher, Frits Hein Wapstra and Albert G Veldhuizen
    Citation: BMC Musculoskeletal Disorders 2010 11:93
  15. Both minimally invasive surgery (MIS) and computer-assisted surgery (CAS) for total hip arthroplasty (THA) have gained popularity in recent years. We conducted a qualitative and systematic review to assess the...

    Authors: Inge HF Reininga, Wiebren Zijlstra, Robert Wagenmakers, Alexander L Boerboom, Bregtje P Huijbers, Johan W Groothoff, Sjoerd K Bulstra and Martin Stevens
    Citation: BMC Musculoskeletal Disorders 2010 11:92
  16. Recent studies have shown high prevalence rates for pelvic girdle pain (PGP) in pregnancy. Some risk factors for developing PGP have been suggested, but the evidence is weak. Furthermore there is almost no dat...

    Authors: Hilde Stendal Robinson, Marit B Veierød, Anne Marit Mengshoel and Nina K Vøllestad
    Citation: BMC Musculoskeletal Disorders 2010 11:91
  17. Cold sensitivity is a common and disabling complaint following hand injuries. The main purpose of this study was to describe self-reported consequences of cold sensitivity and the association with disability a...

    Authors: Ingela K Carlsson, Birgitta Rosén and Lars B Dahlin
    Citation: BMC Musculoskeletal Disorders 2010 11:89
  18. The acid-ash hypothesis, the alkaline diet, and related products are marketed to the general public. Websites, lay literature, and direct mail marketing encourage people to measure their urine pH to assess the...

    Authors: Tanis R Fenton, Misha Eliasziw, Suzanne C Tough, Andrew W Lyon, Jacques P Brown and David A Hanley
    Citation: BMC Musculoskeletal Disorders 2010 11:88
  19. Whilst patellofemoral pain is one of the most common musculoskeletal disorders presenting to orthopaedic clinics, sports clinics, and general practices, factors contributing to its development in the absence o...

    Authors: Stephanie K Tanamas, Andrew J Teichtahl, Anita E Wluka, Yuanyuan Wang, Miranda Davies-Tuck, Donna M Urquhart, Graeme Jones and Flavia M Cicuttini
    Citation: BMC Musculoskeletal Disorders 2010 11:87
  20. Arthritis is a leading cause of disability in the United States. Total knee arthroplasty (TKA) has become the gold standard to manage the pain and disability associated with knee osteoarthritis (OA). Although ...

    Authors: Joseph A Zeni Jr, Michael J Axe and Lynn Snyder-Mackler
    Citation: BMC Musculoskeletal Disorders 2010 11:86
  21. Open fractures frequently result in serious complications for patients, including infections, wound healing problems, and failure of fracture healing, many of which necessitate subsequent operations. One of th...

    Citation: BMC Musculoskeletal Disorders 2010 11:85
  22. Physical performance measures are widely used to assess physical function, providing information about physiological and biomechanical aspects of motor performance. However they do not provide insight into the...

    Authors: Inge HF Reininga, Koen APM Lemmink, Ron L Diercks, Arina T Buizer and Martin Stevens
    Citation: BMC Musculoskeletal Disorders 2010 11:84
  23. Levels of pentosidine (representative of advanced glycation end-products) in sera of patients with rheumatoid arthritis are increased when compared with sera of other diagnoses or healthy controls. These level...

    Authors: Richard Vytášek, Liliana Šedová and Vladimír Vilím
    Citation: BMC Musculoskeletal Disorders 2010 11:83
  24. In the present biomechanical study, the torsional stability of different interference screws, made of bovine bone, was tested. Interference screws derived from bovine bone are a possible biological alternative...

    Authors: Joscha Bauer, Turgay Efe, Silke Herdrich, Leo Gotzen, Bilal Farouk El-Zayat, Jan Schmitt, Nina Timmesfeld and Markus Dietmar Schofer
    Citation: BMC Musculoskeletal Disorders 2010 11:82
  25. Patients with signs of nerve root irritation represent a sub-group of those with low back pain who are at increased risk of persistent symptoms and progression to costly and invasive management strategies incl...

    Authors: Julie M Fritz, Anne Thackeray, John D Childs and Gerard P Brennan
    Citation: BMC Musculoskeletal Disorders 2010 11:81
  26. All patients with total hip arthroplasty (THA), especially those with metal-on-metal (MM) THA, are exposed to metallic particles and ions, which may cause total or site-specific mortality. We analyzed the caus...

    Authors: Tuomo Visuri, Håkan Borg, Pekka Pulkkinen, Pekka Paavolainen and Eero Pukkala
    Citation: BMC Musculoskeletal Disorders 2010 11:78
  27. Intimate partner violence (IPV) is described by the American Medical Association as "a pattern of coercive behaviors that may include repeated battering and injury, psychological abuse, sexual assault, progres...

    Citation: BMC Musculoskeletal Disorders 2010 11:77
  28. Patients with idiopathic carpal tunnel syndrome (CTS) are commonly treated with steroid injection into or proximal to the carpal tunnel. However, evidence for its efficacy beyond one month has not been establi...

    Authors: Magnus Flondell, Manfred Hofer, Jonas Björk and Isam Atroshi
    Citation: BMC Musculoskeletal Disorders 2010 11:76
  29. In patients with osteoarthritis, a detailed assessment of degenerative cartilage disease is important to recommend adequate treatment. Using a representative sample of patients, this study investigated whether...

    Authors: Lars V von Engelhardt, Matthias Lahner, André Klussmann, Bertil Bouillon, Andreas Dàvid, Patrick Haage and Thomas K Lichtinger
    Citation: BMC Musculoskeletal Disorders 2010 11:75
  30. The bone mineral density (BMD) of the distal femur decreases by 16-36% within one year after total knee arthroplasty (TKA) because of the femoral component's stress-shielding effect. The aim of this prospectiv...

    Authors: Hans-Peter W van Jonbergen, Kenneth Koster, Luc Labey, Bernardo Innocenti and Albert van Kampen
    Citation: BMC Musculoskeletal Disorders 2010 11:74
  31. An inverse association between early contact with microbial compounds and respiratory allergies is well established. The protective effect of infant contact with animals was also shown for inflammatory bowel d...

    Authors: Katja Radon, Doris Windstetter, David Poluda, Renate Häfner, Silke Thomas, Hartmut Michels and Erika von Mutius
    Citation: BMC Musculoskeletal Disorders 2010 11:73
  32. Myotonic dystrophy type 1 (DM1) is a multisystem disorder that demonstrates variable symptoms and rates of progression. Muscle weakness is considered one of the main problems with a clinical picture that is ch...

    Authors: Luc J Hébert, Jean-François Remec, Joanne Saulnier, Christophe Vial and Jack Puymirat
    Citation: BMC Musculoskeletal Disorders 2010 11:72
  33. Although hippotherapy treatment has been demonstrated to have therapeutic effects on children with cerebral palsy, the samples used in research studies have been very small. In the case of hippotherapy simulat...

    Authors: Pablo Herrero, Ángel Asensio, Elena García, Álvaro Marco, Barbara Oliván, Alejandro Ibarz, Eva M Gómez-Trullén and Roberto Casas
    Citation: BMC Musculoskeletal Disorders 2010 11:71
  34. Sleep disturbance is becoming increasingly recognised as a clinically important symptom in people with chronic low back pain (CLBP, low back pain >12 weeks), associated with physical inactivity and depression....

    Authors: Deirdre A Hurley, Jennifer Eadie, Grainne O'Donoghue, Clare Kelly, Chris Lonsdale, Suzanne Guerin, Mark A Tully, Willem van Mechelen, Suzanne M McDonough, Colin AG Boreham, Conor Heneghan and Leslie Daly
    Citation: BMC Musculoskeletal Disorders 2010 11:70
  35. If conservative treatment for chronic plantar fasciitis fails, often a corticosteroid injection is given. Corticosteroid injection gives temporarily pain reduction, but no healing. Blood platelets initiate the...

    Authors: Joost C Peerbooms, Wilbert van Laar, Frank Faber, Hans M Schuller, Henk van der Hoeven and Taco Gosens
    Citation: BMC Musculoskeletal Disorders 2010 11:69
  36. A rise in gastrointestinal (GI) adverse events (AEs) and a decline in bone mineral density (BMD) was observed in patients previously tolerant to brand alendronate shortly after generic versions were introduced...

    Authors: Daniel T Grima, Alexandra Papaioannou, Parisa Airia, George Ioannidis and Jonathan D Adachi
    Citation: BMC Musculoskeletal Disorders 2010 11:68
  37. Recent healthcare policy has shifted the management of musculoskeletal conditions in the UK away from secondary care towards Clinical Assessment and Treatment Services at the primary-secondary care interface. ...

    Authors: Edward Roddy, Irena Zwierska, Peter Dawes, Samantha L Hider, Kelvin P Jordan, Jon Packham, Kay Stevenson and Elaine Hay
    Citation: BMC Musculoskeletal Disorders 2010 11:67
  38. There are no standard criteria for defining or assessing severity of fibromyalgia (FM) as a condition as fibromyalgia is associated with multiple symptom domains. The objective of this study was to evaluate wh...

    Authors: Stuart Silverman, Alesia Sadosky, Chris Evans, Yating Yeh, Jose Ma J Alvir and Gergana Zlateva
    Citation: BMC Musculoskeletal Disorders 2010 11:66
  39. Deep vein thrombosis (DVT) has an incidence of 1 case per 1000 inhabitants in the general population and it is very rare after arthroscopy of the shoulder. Therefore, the current guidelines do not advise the a...

    Authors: Raffaele Garofalo, Angela Notarnicola, Lorenzo Moretti, Biagio Moretti, Stefania Marini and Alessandro Castagna
    Citation: BMC Musculoskeletal Disorders 2010 11:65
  40. Hamstring injuries are the most common injury in Australian Rules football. It was the aims to investigate whether a sports chiropractic manual therapy intervention protocol provided in addition to the current...

    Authors: Wayne Hoskins and Henry Pollard
    Citation: BMC Musculoskeletal Disorders 2010 11:64

    The Erratum to this article has been published in BMC Musculoskeletal Disorders 2011 12:200

  41. Phosphoinositide 3-kinase γ (PI3Kγ) has been depicted as a major regulator of inflammatory processes, including leukocyte activation and migration towards several chemokines. This study aims to explore the rol...

    Authors: Michael Gruen, Christina Rose, Christian König, Mieczyslaw Gajda, Reinhard Wetzker and Rolf Bräuer
    Citation: BMC Musculoskeletal Disorders 2010 11:63
  42. Calcitonin has been demonstrated to have chondroprotective effects under pre-clinical settings. It is debated whether this effect is mediated through subchondral-bone, directly on cartilage or both in combinat...

    Authors: Bodil-Cecilie Sondergaard, Suzi H Madsen, Toni Segovia-Silvestre, Sarah J Paulsen, Thorbjorn Christiansen, Christian Pedersen, Anne-Christine Bay-Jensen and Morten A Karsdal
    Citation: BMC Musculoskeletal Disorders 2010 11:62
  43. Macrophages expressing the pro-angiogenic transcription factor hypoxia-inducible factor (HIF)-1alpha have been demonstrated in rheumatoid arthritis (RA) in the synovial tissue. Aim of the present study was to ...

    Authors: Johanna Westra, Elisabeth Brouwer, Ingrid AM van Roosmalen, Berber Doornbos-van der Meer, Miek A van Leeuwen, Marcel D Posthumus and Cees GM Kallenberg
    Citation: BMC Musculoskeletal Disorders 2010 11:61
  44. Within the working population there is a vulnerable group: workers without an employment contract and workers with a flexible labour market arrangement, e.g. temporary agency workers. In most cases, when sick-...

    Authors: Sylvia J Vermeulen, Johannes R Anema, Antonius JM Schellart, Willem van Mechelen and Allard J van der Beek
    Citation: BMC Musculoskeletal Disorders 2010 11:60
  45. The relative contribution of lean and fat to the determination of bone mineral density (BMD) in postmenopausal women is a contentious issue. The present study was undertaken to test the hypothesis that lean ma...

    Authors: Lan T Ho-Pham, Nguyen D Nguyen, Thai Q Lai and Tuan V Nguyen
    Citation: BMC Musculoskeletal Disorders 2010 11:59
  46. Systematic reviews have shown that exercise therapy and spinal manipulation are both more effective for low back pain (LBP) than no treatment at all. However, the effects are at best modest. To enhance the cli...

    Authors: Adri T Apeldoorn, Raymond W Ostelo, Hans van Helvoirt, Julie M Fritz, Henrika CW de Vet and Maurits W van Tulder
    Citation: BMC Musculoskeletal Disorders 2010 11:58
  47. Correct rotational alignment of the femoral and tibial component is an important factor for successful TKA. The transepicondylar axis is widely accepted as a reference for the femoral component. There is not a...

    Authors: Jörg Lützner, Frank Krummenauer, Klaus-Peter Günther and Stephan Kirschner
    Citation: BMC Musculoskeletal Disorders 2010 11:57

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