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  1. Recent healthcare policy has shifted the management of musculoskeletal conditions in the UK away from secondary care towards Clinical Assessment and Treatment Services at the primary-secondary care interface. ...

    Authors: Edward Roddy, Irena Zwierska, Peter Dawes, Samantha L Hider, Kelvin P Jordan, Jon Packham, Kay Stevenson and Elaine Hay
    Citation: BMC Musculoskeletal Disorders 2010 11:67
  2. There are no standard criteria for defining or assessing severity of fibromyalgia (FM) as a condition as fibromyalgia is associated with multiple symptom domains. The objective of this study was to evaluate wh...

    Authors: Stuart Silverman, Alesia Sadosky, Chris Evans, Yating Yeh, Jose Ma J Alvir and Gergana Zlateva
    Citation: BMC Musculoskeletal Disorders 2010 11:66
  3. Deep vein thrombosis (DVT) has an incidence of 1 case per 1000 inhabitants in the general population and it is very rare after arthroscopy of the shoulder. Therefore, the current guidelines do not advise the a...

    Authors: Raffaele Garofalo, Angela Notarnicola, Lorenzo Moretti, Biagio Moretti, Stefania Marini and Alessandro Castagna
    Citation: BMC Musculoskeletal Disorders 2010 11:65
  4. Hamstring injuries are the most common injury in Australian Rules football. It was the aims to investigate whether a sports chiropractic manual therapy intervention protocol provided in addition to the current...

    Authors: Wayne Hoskins and Henry Pollard
    Citation: BMC Musculoskeletal Disorders 2010 11:64

    The Erratum to this article has been published in BMC Musculoskeletal Disorders 2011 12:200

  5. Phosphoinositide 3-kinase γ (PI3Kγ) has been depicted as a major regulator of inflammatory processes, including leukocyte activation and migration towards several chemokines. This study aims to explore the rol...

    Authors: Michael Gruen, Christina Rose, Christian König, Mieczyslaw Gajda, Reinhard Wetzker and Rolf Bräuer
    Citation: BMC Musculoskeletal Disorders 2010 11:63
  6. Calcitonin has been demonstrated to have chondroprotective effects under pre-clinical settings. It is debated whether this effect is mediated through subchondral-bone, directly on cartilage or both in combinat...

    Authors: Bodil-Cecilie Sondergaard, Suzi H Madsen, Toni Segovia-Silvestre, Sarah J Paulsen, Thorbjorn Christiansen, Christian Pedersen, Anne-Christine Bay-Jensen and Morten A Karsdal
    Citation: BMC Musculoskeletal Disorders 2010 11:62
  7. Macrophages expressing the pro-angiogenic transcription factor hypoxia-inducible factor (HIF)-1alpha have been demonstrated in rheumatoid arthritis (RA) in the synovial tissue. Aim of the present study was to ...

    Authors: Johanna Westra, Elisabeth Brouwer, Ingrid AM van Roosmalen, Berber Doornbos-van der Meer, Miek A van Leeuwen, Marcel D Posthumus and Cees GM Kallenberg
    Citation: BMC Musculoskeletal Disorders 2010 11:61
  8. Within the working population there is a vulnerable group: workers without an employment contract and workers with a flexible labour market arrangement, e.g. temporary agency workers. In most cases, when sick-...

    Authors: Sylvia J Vermeulen, Johannes R Anema, Antonius JM Schellart, Willem van Mechelen and Allard J van der Beek
    Citation: BMC Musculoskeletal Disorders 2010 11:60
  9. The relative contribution of lean and fat to the determination of bone mineral density (BMD) in postmenopausal women is a contentious issue. The present study was undertaken to test the hypothesis that lean ma...

    Authors: Lan T Ho-Pham, Nguyen D Nguyen, Thai Q Lai and Tuan V Nguyen
    Citation: BMC Musculoskeletal Disorders 2010 11:59
  10. Systematic reviews have shown that exercise therapy and spinal manipulation are both more effective for low back pain (LBP) than no treatment at all. However, the effects are at best modest. To enhance the cli...

    Authors: Adri T Apeldoorn, Raymond W Ostelo, Hans van Helvoirt, Julie M Fritz, Henrika CW de Vet and Maurits W van Tulder
    Citation: BMC Musculoskeletal Disorders 2010 11:58
  11. Correct rotational alignment of the femoral and tibial component is an important factor for successful TKA. The transepicondylar axis is widely accepted as a reference for the femoral component. There is not a...

    Authors: Jörg Lützner, Frank Krummenauer, Klaus-Peter Günther and Stephan Kirschner
    Citation: BMC Musculoskeletal Disorders 2010 11:57
  12. Self-management has become increasingly popular in the management of chronic diseases. There are many different self-management models. Meta analyses of arthritis self-management have concluded that it is diff...

    Authors: Sophie Coleman, Jean McQuade, Jessica Rose, Charles Inderjeeth, Graeme Carroll and N Kathryn Briffa
    Citation: BMC Musculoskeletal Disorders 2010 11:56
  13. One in four Swedish women suffers a hip fracture yielding high morbidity and mortality. We wanted to revalidate a 4-item clinical risk score and evaluate a portable heel bone mineral density (BMD) technique re...

    Authors: Daniel Albertsson, Dan Mellström, Christer Petersson, Hans Thulesius and Robert Eggertsen
    Citation: BMC Musculoskeletal Disorders 2010 11:55
  14. It has not been assessed before whether mathematical models described in the literature for prescriptions of exercise can be used for fibromyalgia syndrome patients. The objective of this paper was to determin...

    Authors: Maria Carolina D Lemos, Valéria Valim, Eliana Zandonade and Jamil Natour
    Citation: BMC Musculoskeletal Disorders 2010 11:54
  15. Hyperbaric oxygen (HBO) therapy has been proved in improving bone healing, but its effects on mesenchymal stem cells (MSCs) in vivo is not clear. The aims of this study are to clarify whether the HBO therapy has ...

    Authors: Tsai-Sheng Fu, Steve WN Ueng, Tsung-Ting Tsai, Lih-Huei Chen, Song-Shu Lin and Wen-Jer Chen
    Citation: BMC Musculoskeletal Disorders 2010 11:52
  16. To explore how chronic musculoskeletal pain is managed in multidisciplinary pain clinics for patients for whom physical interventions are inappropriate or ineffective.

    Authors: Geoffrey Harding, John Campbell, Suzanne Parsons, Anisur Rahman and Martin Underwood
    Citation: BMC Musculoskeletal Disorders 2010 11:51
  17. Barriers to care limit the potential benefits of pharmacological intervention for inflammatory arthritis. A self-administered questionnaire for early inflammatory arthritis (EIA) detection may complement conte...

    Authors: Mary J Bell, Ruben Tavares, Francis Guillemin, Vivian P Bykerk, Peter Tugwell and George A Wells
    Citation: BMC Musculoskeletal Disorders 2010 11:50
  18. The number of hip fractures during recent decades has been reported to be increasing, partly because of an increasing proportion of elderly women in the society. However, whether changes in hip fracture annual...

    Authors: Henrik G Ahlborg, Björn E Rosengren, Teppo LN Järvinen, Cecilia Rogmark, Jan-Åke Nilsson, Ingemar Sernbo and Magnus K Karlsson
    Citation: BMC Musculoskeletal Disorders 2010 11:48
  19. The flexion relaxation phenomenon (FRP) represents a well-studied neuromuscular response that occurs in the lumbar and cervical spine. However, the cervical spine FRP has not been investigated extensively, and...

    Authors: Jean-Philippe Pialasse, Danik Lafond, Vincent Cantin and Martin Descarreaux
    Citation: BMC Musculoskeletal Disorders 2010 11:46
  20. Subacromial impingement syndrome (SIS) is a commonly reported cause of shoulder pain. The purpose of this study was to systematically review the literature to examine whether a difference in electromyographic ...

    Authors: Rachel Chester, Toby O Smith, Lee Hooper and John Dixon
    Citation: BMC Musculoskeletal Disorders 2010 11:45
  21. Ultrasonography of temporal arteries is not commonly used in the approach of patients with suspected giant cell arteritis (GCA) in clinical practice. A meta-analysis of primary studies available through April ...

    Authors: Aikaterini Arida, Miltiades Kyprianou, Meletios Kanakis and Petros P Sfikakis
    Citation: BMC Musculoskeletal Disorders 2010 11:44
  22. Rheumatoid arthritis (RA) is a chronic, inflammatory and systemic disease which affects the musculoskeletal system. Exercise programmes are reported to improve physical functioning in patients with RA. Tai Chi...

    Authors: Till Uhlig, Camilla Fongen, Eldri Steen, Anne Christie and Sigrid Ødegård
    Citation: BMC Musculoskeletal Disorders 2010 11:43
  23. fibromyalgia is a relatively common condition with widespread pain and pressure allodynia, but unknown aetiology. For decades, the association between motor control strategies and chronic pain has been a topic...

    Authors: Björn Gerdle, Christer Grönlund, Stefan J Karlsson, Andreas Holtermann and Karin Roeleveld
    Citation: BMC Musculoskeletal Disorders 2010 11:42
  24. Adiposity is a modifiable factor that has been implicated in tendinopathy. As tendon pain reduces physical activity levels and can lead to weight gain, associations between tendon pathology and adiposity must ...

    Authors: James E Gaida, Håkan Alfredson, Zoltan S Kiss, Shona L Bass and Jill L Cook
    Citation: BMC Musculoskeletal Disorders 2010 11:41
  25. Post-menopausal osteopenic women are at increased risk for skeletal fractures. Current osteopenia treatment guidelines include exercise, however, optimal exercise regimens for attenuating bone mineral density ...

    Authors: Peter M Wayne, Julie E Buring, Roger B Davis, Ellen M Connors, Paolo Bonato, Benjamin Patritti, Mary Fischer, Gloria Y Yeh, Calvin J Cohen, Danette Carroll and Douglas P Kiel
    Citation: BMC Musculoskeletal Disorders 2010 11:40
  26. Clinical sagittal plane assessment of the thoracic kyphosis angle is considered an essential component of the postural examination of patients presenting with upper body pain syndromes. Cervical headaches and ...

    Authors: Jeremy S Lewis and Rachel E Valentine
    Citation: BMC Musculoskeletal Disorders 2010 11:39
  27. The foot is often affected in patients with rheumatoid arthritis. Subtalar joints are involved more frequently than ankle joints. Deformities of subtalar joints often lead to painful flatfoot and valgus deform...

    Authors: Stanislav Popelka, Rastislav Hromádka, Pavel Vavřík, Pavel Štursa, David Pokorný, David Jahoda and Antonín Sosna
    Citation: BMC Musculoskeletal Disorders 2010 11:38
  28. This randomised, single-blind controlled pilot trial aimed to determine the effectiveness of a physiotherapy program, including exercise and manual therapy, in reducing impairments and improving physical funct...

    Authors: Kim L Bennell, Bernadette Matthews, Alison Greig, Andrew Briggs, Anne Kelly, Margaret Sherburn, Judy Larsen and John Wark
    Citation: BMC Musculoskeletal Disorders 2010 11:36
  29. Osteoporosis is a bone disease that can reduce both bone mass and bone strength. It can cause serious fractures of bones, along with causing significant and even devastating physical, psychological and financi...

    Authors: Jenn-Huei Renn, Nan-Ping Yang and Pesus Chou
    Citation: BMC Musculoskeletal Disorders 2010 11:35
  30. Angiogenesis plays a role in the progression of osteosarcoma, as well as in other mesenchymal tumors and carcinomas, and it is most commonly assessed by vascular endothelial growth factor (VEGF) expression or ...

    Authors: Barbara Rossi, Giovanni Schinzari, Giulio Maccauro, Laura Scaramuzzo, Diego Signorelli, Michele A Rosa, Carlo Fabbriciani and Barone Carlo
    Citation: BMC Musculoskeletal Disorders 2010 11:34
  31. Non-specific low back pain (LBP) is usually self-limiting within 4-6 weeks. Longstanding pain and disability are not predictable from clinical signs or pathoanatomical findings. Pain cognition and physical per...

    Authors: Erik L Werner, Kjersti Storheim, Ida Løchting and Margreth Grotle
    Citation: BMC Musculoskeletal Disorders 2010 11:33
  32. Myofascial pain is a common dysfunction with a lifetime prevalence affecting up to 85% of the general population. Current guidelines for the management of myofascial pain are not available. In this study we in...

    Authors: Johannes Fleckenstein, Daniela Zaps, Linda J Rüger, Lukas Lehmeyer, Florentina Freiberg, Philip M Lang and Dominik Irnich
    Citation: BMC Musculoskeletal Disorders 2010 11:32
  33. To explore the health beliefs, experiences, treatment and expectations of people with chronic knee pain, and investigate if, how and why these change after taking part on an integrated exercise-based rehabilit...

    Authors: Michael V Hurley, Nicola Walsh, Vanita Bhavnani, Nicky Britten and Fiona Stevenson
    Citation: BMC Musculoskeletal Disorders 2010 11:31
  34. Active approaches including both specific and unspecific exercise are probably the most widely recommended treatment for patients with chronic low back pain but it is not known exactly which types of exercise ...

    Authors: Jan Hartvigsen, Lars Morsø, Tom Bendix and Claus Manniche
    Citation: BMC Musculoskeletal Disorders 2010 11:30
  35. The cervical zygapophyseal joints may be a primary source of pain in up to 60% of individuals with chronic whiplash associated disorders (WAD) and may be a contributing factor for peripheral and centrally medi...

    Authors: Geoff M Schneider, Ashley D Smith, Allen Hooper, Paul Stratford, Kathryn J Schneider, Michael D Westaway, Bevan Frizzell and Lee Olson
    Citation: BMC Musculoskeletal Disorders 2010 11:29
  36. Patellar tendinopathy is a major problem for many athletes, especially those involved in jumping activities. Despite its frequency and negative impact on athletic careers, no evidence-based guidelines for mana...

    Authors: Johannes Zwerver, Evert Verhagen, Fred Hartgens, Inge van den Akker-Scheek and Ron L Diercks
    Citation: BMC Musculoskeletal Disorders 2010 11:28
  37. Minimal invasion surgery (MIS) is a recent technique recommended for Total knee arthroplasty (TKA) but demands an effort of the surgeons and the learning curve may be long.

    Authors: Daniel Hernandez-Vaquero, Alfonso Noriega-Fernandez and Abelardo Suarez-Vazquez
    Citation: BMC Musculoskeletal Disorders 2010 11:27
  38. Back and neck pain are very common, disabling and recurrent disorders in the general population and the knowledge of long-term effect of treatments are sparse. The aim of this study was to compare the long-ter...

    Authors: Eva Skillgate, Tony Bohman, Lena W Holm, Eva Vingård and Lars Alfredsson
    Citation: BMC Musculoskeletal Disorders 2010 11:26
  39. Walking and cycling to school are one source of regular physical activity. The aim of this two years observational study in pre-pubertal children was to evaluate if walking and cycling to school was associated...

    Authors: Bjarne Löfgren, Susanna Stenevi-Lundgren, Magnus Dencker and Magnus K Karlsson
    Citation: BMC Musculoskeletal Disorders 2010 11:25
  40. It is known that when barefoot, gait biomechanics of diabetic neuropathic patients differ from non-diabetic individuals. However, it is still unknown whether these biomechanical changes are also present during...

    Authors: Isabel CN Sacco, Paula MH Akashi and Ewald M Hennig
    Citation: BMC Musculoskeletal Disorders 2010 11:24
  41. Work related upper limb disorders constitute 45% of all occupational diseases and are a significant public health problem. A subgroup, non specific arm pain (NSAP), remains elusive in terms of understanding it...

    Authors: Niamh Moloney, Toby Hall and Catherine Doody
    Citation: BMC Musculoskeletal Disorders 2010 11:22
  42. The Effective Musculoskeletal Consumer Scale (EC-17) is a self-administered questionnaire for evaluating self-management interventions that empower and educate people with rheumatic conditions. The aim of the ...

    Authors: Bente Hamnes, Andrew Garratt, Ingvild Kjeken, Elizabeth Kristjansson and Kåre B Hagen
    Citation: BMC Musculoskeletal Disorders 2010 11:21
  43. Previous research has shown that underlying dietary patterns are related to the risk of many different adverse health outcomes, but the relationship of these underlying patterns to skeletal fragility is not we...

    Authors: Lisa Langsetmo, Suzette Poliquin, David A Hanley, Jerilynn C Prior, Susan Barr, Tassos Anastassiades, Tanveer Towheed, David Goltzman and Nancy Kreiger
    Citation: BMC Musculoskeletal Disorders 2010 11:20
  44. Menisci play a vital role in load transmission, shock absorption and joint stability. There is increasing evidence suggesting that OA menisci may not merely be bystanders in the disease process of OA. This stu...

    Authors: Yubo Sun, David R Mauerhan, Patrick R Honeycutt, Jeffrey S Kneisl, James H Norton, Edward N Hanley Jr and Helen E Gruber
    Citation: BMC Musculoskeletal Disorders 2010 11:19
  45. Pfeifer-Weber-Christian disease (PWCD) is a rare inflammatory disorder of the subcutaneous fatty tissue. The diagnosis and therapy of this rare type of panniculitis is still controversial and will be discussed...

    Authors: Georg Pongratz, Boris Ehrenstein, Wolfgang Hartung, Jürgen Schölmerich and Martin Fleck
    Citation: BMC Musculoskeletal Disorders 2010 11:18

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