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  1. Shoulder problems are a common complaint of the musculoskeletal system. Physical therapists treat these patients with different modalities such as exercise, massage, and shoulder taping. Although different tec...

    Authors: Joeri Kalter, Adri T Apeldoorn, Raymond W Ostelo, Nicholas Henschke, Dirk L Knol and Maurits W van Tulder
    Citation: BMC Musculoskeletal Disorders 2011 12:188
  2. Periprosthetic osteolysis is a major cause of aseptic loosening in joint arthroplasty. This study investigates the impact of CT (calcitonin) deficiency and CT substitution under in-vivo circumstances on partic...

    Authors: Max D Kauther, Hagen S Bachmann, Laura Neuerburg, Martina Broecker-Preuss, Gero Hilken, Florian Grabellus, Gabriele Koehler, Marius von Knoch and Christian Wedemeyer
    Citation: BMC Musculoskeletal Disorders 2011 12:186
  3. Skeletal muscle atrophy is a serious concern for the rehabilitation of patients afflicted by prolonged limb restriction. This debilitating condition is associated with a marked activation of NFκB activity. The...

    Authors: Annabelle Z Caron, Sonia Haroun, Élisabeth Leblanc, Frédéric Trensz, Chantal Guindi, Aziz Amrani and Guillaume Grenier
    Citation: BMC Musculoskeletal Disorders 2011 12:185
  4. Stiffness with decreased range of motion (ROM) has been described as a frustrating complication after TKA. If all methods of physiotherapeutic treatment have been exhausted trying to develop ROM, manipulation ...

    Authors: Ingmar Ipach, Falk Mittag, Julia Lahrmann, Beate Kunze and Torsten Kluba
    Citation: BMC Musculoskeletal Disorders 2011 12:184
  5. Modic changes (MCs) have been identified as a diagnostic subgroup associated with low back pain (LBP). The aetiology of MCs is still unknown and there is no effective treatment available. If MCs constitute a s...

    Authors: Rikke K Jensen and Charlotte Leboeuf-Yde
    Citation: BMC Musculoskeletal Disorders 2011 12:183
  6. The trapezius muscle is a neck muscle that is susceptible to chronic pain conditions associated with repetitive tasks, commonly referred to as chronic work-related myalgia, hence making the trapezius a muscle ...

    Authors: Jenny Hadrévi, Fredrik Hellström, Thomas Kieselbach, Christer Malm and Fatima Pedrosa-Domellöf
    Citation: BMC Musculoskeletal Disorders 2011 12:181
  7. The established treatment for bacterial arthritis of the knee joint is arthroscopic surgery with irrigation and debridement. The aim of this article is to summarize the relevant data in treating bacterial arth...

    Authors: Atesch Ateschrang, Dirk Albrecht, Steffen Schröter, Bernhard Hirt, Kuno Weise and Jürgen H Dolderer
    Citation: BMC Musculoskeletal Disorders 2011 12:180
  8. Chronic low back pain is a highly prevalent condition, which is associated with high direct and indirect costs to the society. Although this condition is highly prevalent, it is still extremely difficult to tr...

    Authors: Alessandra N Garcia, Francine LB Gondo, Renata A Costa, Fábio N Cyrillo, Tatiane M Silva, Luciola CM Costa and Leonardo OP Costa
    Citation: BMC Musculoskeletal Disorders 2011 12:179
  9. A study to evaluate the adherence to and appropriateness of anti-osteoporotic treatments in a cohort of men and women aged 50 and over participating in the ESOSVAL-R study.

    Authors: Gabriel Sanfélix-Gimeno, José Sanfélix-Genovés, Salvador Peiró, Isabel Hurtado, José Luis Trillo, Ruth Usó, Vicente Giner Ruiz, Manuel Pascual de la Torre and Inmaculada Ferreros
    Citation: BMC Musculoskeletal Disorders 2011 12:178
  10. Osteoarthritis (OA) is a prevalent chronic disease and a leading cause of disability in adults. For people with knee and hip OA, symptoms (e.g., pain and fatigue) can interfere with mobility and physical activ...

    Authors: Susan L Murphy, Angela K Lyden, Maria Clary, Michael E Geisser, Raymond L Yung, Daniel J Clauw and David A Williams
    Citation: BMC Musculoskeletal Disorders 2011 12:177
  11. Neck pain is related to impaired postural balance among patients and is highly prevalent among workers with high postural demands, for example, cleaners. We therefore hypothesised, that cleaners with neck pain...

    Authors: Marie B Jørgensen, Jørgen H Skotte, Andreas Holtermann, Gisela Sjøgaard, Nicolas C Petersen and Karen Søgaard
    Citation: BMC Musculoskeletal Disorders 2011 12:176
  12. Beside symptoms and clinical signs radiological findings are crucial in the diagnosis of lumbar spinal stenosis (LSS). We investigate which quantitative radiological signs are described in the literature and w...

    Authors: Johann Steurer, Simon Roner, Ralph Gnannt and Juerg Hodler
    Citation: BMC Musculoskeletal Disorders 2011 12:175
  13. Hypersensitivity of the central nervous system is widely present in pain patients and recognized as one of the determinants of chronic pain and disability. Electronic pressure algometry is often used to explor...

    Authors: Niklaus Egloff, Nicole Klingler, Roland von Känel, Rafael JA Cámara, Michele Curatolo, Barbara Wegmann, Elizabeth Marti and Marie-Louise Gander Ferrari
    Citation: BMC Musculoskeletal Disorders 2011 12:174
  14. In the light of both the importance and large numbers of case series and cohort studies (observational studies) in orthopaedic literature, it is remarkable that there is currently no validated measurement tool...

    Authors: Bart G Pijls, Olaf M Dekkers, Saskia Middeldorp, Edward R Valstar, Huub JL van der Heide, Henrica MJ Van der Linden-Van der Zwaag and Rob GHH Nelissen
    Citation: BMC Musculoskeletal Disorders 2011 12:173
  15. The expectations of patients for managing pain induced by exercise and mobilization (PIEM) have seldom been investigated. We identified the views of patients and care providers regarding pain management induce...

    Authors: Sophie Alami, Dominique Desjeux, Marie Martine Lefèvre-Colau, Anne Sophie Boisgard, Eric Boccard, François Rannou and Serge Poiraudeau
    Citation: BMC Musculoskeletal Disorders 2011 12:172
  16. There is a need for outcome measurement instruments for evaluation of disability after trauma. The Patient-Rated Wrist Evaluation (PRWE) is a self-administered region-specific outcome measuring instrument deve...

    Authors: Cecilia Mellstrand Navarro, Sari Ponzer, Hans Törnkvist, Leif Ahrengart and Gunnar Bergström
    Citation: BMC Musculoskeletal Disorders 2011 12:171
  17. While there is growing evidence for the efficacy of SM to treat LBP, little is known on the mechanisms and physiologic effects of these treatments. Accordingly, the purpose of this study was to determine wheth...

    Authors: Brian C Clark, David A Goss Jr, Stevan Walkowski, Richard L Hoffman, Andrew Ross and James S Thomas
    Citation: BMC Musculoskeletal Disorders 2011 12:170
  18. Many adults experience bothersome neck/shoulder pain. While research and treatment strategies often focus on the upper trapezius, other neck/shoulder muscles may be affected as well. The aim of the present stu...

    Authors: Lars L Andersen, Klaus Hansen, Ole S Mortensen and Mette K Zebis
    Citation: BMC Musculoskeletal Disorders 2011 12:169
  19. Assessment of shoulder mobility is essential for clinical follow-up of shoulder treatment. Only a few high sophisticated instruments for objective measurements of shoulder mobility are available. The interobse...

    Authors: Bilal Farouk El-Zayat, Turgay Efe, Annett Heidrich, Udo Wolf, Nina Timmesfeld, Thomas J Heyse, Stefan Lakemeier, Susanne Fuchs-Winkelmann and Markus D Schofer
    Citation: BMC Musculoskeletal Disorders 2011 12:168
  20. Monitoring osteoporosis therapy by measurement of bone turnover markers (BTMs) might detect non-compliance in an earlier stage of anti-osteoporosis treatment and improve persistence.

    Authors: Danielle A Eekman, Irene EM Bultink, Annemieke C Heijboer, Ben AC Dijkmans and Willem F Lems
    Citation: BMC Musculoskeletal Disorders 2011 12:167
  21. To determine safe surgical margins for soft tissue sarcoma, it is essential to perform a general evaluation of the extent of tumor, responses to auxiliary therapy, and other factors preoperatively using multip...

    Authors: Masahiro Yokouchi, Mikio Terahara, Satoshi Nagano, Yoshiya Arishima, Michihisa Zemmyo, Takako Yoshioka, Akihide Tanimoto and Setsuro Komiya
    Citation: BMC Musculoskeletal Disorders 2011 12:166
  22. Clinical analgesic trials typically report response as group mean results. However, research has shown that few patients are average and most have responses at the extremes. Moreover, group mean results do not...

    Authors: Paul M Peloso, Arnold Gammaitoni, Steven S Smugar, Hongwei Wang and Andrew R Moore
    Citation: BMC Musculoskeletal Disorders 2011 12:165
  23. Tenascin-C (TN-C) is an extracellular matrix glycoprotein that is involved in tissue injury and repair processes. We analyzed TN-C expression in normal and osteoarthritic (OA) human cartilage, and evaluated it...

    Authors: Lisha Patel, Weiyong Sun, Sonya S Glasson, Elisabeth A Morris, Carl R Flannery and Priya S Chockalingam
    Citation: BMC Musculoskeletal Disorders 2011 12:164
  24. BMP-2 is known to accelerate fracture healing and might also enhance osseointegration and implant fixation. Application of recombinant BMP-2 has a time-limited effect. Therefore, a gene transfer approach with ...

    Authors: Benjamin Faensen, Britt Wildemann, Christian Hain, Julius Höhne, Yvonne Funke, Christan Plank, Axel Stemberger and Gerhard Schmidmaier
    Citation: BMC Musculoskeletal Disorders 2011 12:163
  25. Increased center of pressure excursions are well documented in patients suffering from non-specific low back pain, whereby the altered postural sway includes both higher mean sway velocities and larger sway ar...

    Authors: Alexander Ruhe, René Fejer and Bruce Walker
    Citation: BMC Musculoskeletal Disorders 2011 12:162
  26. Despite the large volume of research dedicated to understanding chronic low back pain (CLBP), patient outcomes remain modest while healthcare costs continue to rise, creating a major public health burden. Heal...

    Authors: Andrew M Briggs, Joanne E Jordan, Peter B O'Sullivan, Rachelle Buchbinder, Angus F Burnett, Richard H Osborne and Leon M Straker
    Citation: BMC Musculoskeletal Disorders 2011 12:161
  27. The pathogenesis of osteonecrosis of the femoral head (ONFH) has been implicated in hypofibrinolysis and blood supply interruption. Previous studies have demonstrated that decreased fibrinolytic activity due t...

    Authors: Hye- Ok Kim, Chang- Hoon Cho, Yoon- Je Cho, Seong- Ho Cho, Kyung- Sik Yoon and Kang- Il Kim
    Citation: BMC Musculoskeletal Disorders 2011 12:160
  28. Authors: Wayne Hoskins, Henry Pollard, Chris Daff, Andrew Odell, Peter Garbutt, Andrew McHardy, Kate Hardy and George Dragasevic
    Citation: BMC Musculoskeletal Disorders 2011 12:159

    The original article was published in BMC Musculoskeletal Disorders 2010 11:241

  29. Authors: Wayne Hoskins, Henry Pollard, Chris Daff, Andrew Odell, Peter Garbutt, Andrew McHardy, Kate Hardy and George Dragasevic
    Citation: BMC Musculoskeletal Disorders 2011 12:158

    The original article was published in BMC Musculoskeletal Disorders 2009 10:38

  30. Musculoskeletal diseases are becoming increasingly important due to population aging. However, studies on the economic burden of musculoskeletal disease in Korea are scarce. Therefore, we conducted a populatio...

    Authors: In-Hwan Oh, Seok-Jun Yoon, Hye-Young Seo, Eun-Jung Kim and Young Ae Kim
    Citation: BMC Musculoskeletal Disorders 2011 12:157
  31. There is limited evidence for the clinical and cost effectiveness of occupational therapy (OT) approaches in the management of hand osteoarthritis (OA). Joint protection and hand exercises have been proposed b...

    Authors: Krysia S Dziedzic, Susan Hill, Elaine Nicholls, Alison Hammond, Helen Myers, Tracy Whitehurst, Jo Bailey, Charlotte Clements, David GT Whitehurst, Sue Jowett, June Handy, Rhian W Hughes, Elaine Thomas and Elaine M Hay
    Citation: BMC Musculoskeletal Disorders 2011 12:156
  32. Even though technological progress has provided us with more and more sophisticated equipment for making goniometric measurements, the most commonly used clinical tools are still the universal goniometer and, ...

    Authors: Pablo Herrero, Patricia Carrera, Elena García, Eva M Gómez-Trullén and Bárbara Oliván-Blázquez
    Citation: BMC Musculoskeletal Disorders 2011 12:155
  33. Subacromial disorders are considered to be one of the most common pathologies affecting the shoulder. Optimal therapy for shoulder pain (SP) in primary care is yet unknown, since clinical history and physical ...

    Authors: Ramon PG Ottenheijm, Manuela A Joore, Geert HIM Walenkamp, René E Weijers, Bjorn Winkens, Jochen WL Cals, Rob A de Bie and Geert-Jan Dinant
    Citation: BMC Musculoskeletal Disorders 2011 12:154
  34. Canakinumab is a fully human anti-interleukin IL-1beta monoclonal antibody, being investigated for the treatment of rheumatoid arthritis (RA). This multicenter, phase II, randomized, double-blind, placebo-cont...

    Authors: Rieke Alten, Juan Gomez-Reino, Patrick Durez, Andre Beaulieu, Anthony Sebba, Gerhard Krammer, Ralph Preiss, Udayasankar Arulmani, Albert Widmer, Xavier Gitton and Herbert Kellner
    Citation: BMC Musculoskeletal Disorders 2011 12:153
  35. Brief intervention programs are clinically beneficial, and cost efficient treatments for low back pain, when offered at 8-12 weeks, compared with treatment as usual. However, about 30% of the patients do not r...

    Authors: Silje E Reme, Torill H Tveito, Trudie Chalder, Tormod Bjørkkjær, Aage Indahl, Jens I Brox, Egil Fors, Eli M Hagen and Hege R Eriksen
    Citation: BMC Musculoskeletal Disorders 2011 12:152
  36. Posttraumatic osteoarthritis can develop after an intra-articular extremity fracture, leading to pain and loss of function. According to international guidelines, anatomical reduction and fixation are the basi...

    Authors: M Suzan H Beerekamp, Dirk Th Ubbink, Mario Maas, Jan SK Luitse, Peter Kloen, Taco JM Blokhuis, Michiel JM Segers, Meir Marmor, Niels WL Schep, Marcel GW Dijkgraaf and J Carel Goslings
    Citation: BMC Musculoskeletal Disorders 2011 12:151
  37. Regulation of cell death and cell division are key processes during chondrogenesis and in cartilage homeostasis and pathology. The oncogene survivin is considered to be critical for the coordination of mitosis...

    Authors: Philipp Lechler, Sanjeevi Balakrishnan, Jens Schaumburger, Susanne Grässel, Clemens Baier, Joachim Grifka, Rainer H Straub and Tobias Renkawitz
    Citation: BMC Musculoskeletal Disorders 2011 12:150
  38. A high quality decision requires that patients who meet clinical criteria for surgery are informed about the options (including non-surgical alternatives) and receive treatments that match their goals. The aim...

    Authors: Karen R Sepucha, Dawn Stacey, Catharine F Clay, Yuchiao Chang, Carol Cosenza, Geoffrey Dervin, Janet Dorrwachter, Sandra Feibelmann, Jeffrey N Katz, Stephen A Kearing, Henrik Malchau, Monica Taljaard, Ivan Tomek, Peter Tugwell and Carrie A Levin
    Citation: BMC Musculoskeletal Disorders 2011 12:149
  39. Ankle fractures are common. Management of ankle fractures generally involves a period of immobilisation followed by rehabilitation to reduce pain, stiffness, weakness and swelling. The effects of a rehabilitat...

    Authors: Paula R Beckenkamp, C Christine Lin, Robert D Herbert, Marion Haas, Kriti Khera and Anne M Moseley
    Citation: BMC Musculoskeletal Disorders 2011 12:148
  40. The present study was conducted to address whether the intervertebral disc of rabbit could be considered (i) as a valuable model to provide new insights into the tissue and cellular changes of Nucleus pulposus...

    Authors: Johann Clouet, Marianne Pot-Vaucel, Gaël Grimandi, Martial Masson, Julie Lesoeur, Borhane H Fellah, Olivier Gauthier, Marion Fusellier, Yan Cherel, Yves Maugars, Jérôme Guicheux and Claire Vinatier
    Citation: BMC Musculoskeletal Disorders 2011 12:147
  41. Patients with non-specific back pain are not a homogeneous group but heterogeneous with regard to their bio-psycho-social impairments. This study examined a sample of 173 highly disabled patients with chronic ...

    Authors: Martin L Verra, Felix Angst, J Bart Staal, Roberto Brioschi, Susanne Lehmann, André Aeschlimann and Rob A de Bie
    Citation: BMC Musculoskeletal Disorders 2011 12:145
  42. One of the sources of knee pain in osteoarthritis (OA) is believed to be related to local chronic inflammation of the knee joints, which involves the production of inflammatory cytokines such as tumor necrosis...

    Authors: Sumihisa Orita, Takana Koshi, Takeshi Mitsuka, Masayuki Miyagi, Gen Inoue, Gen Arai, Tetsuhiro Ishikawa, Eiji Hanaoka, Keishi Yamashita, Masaomi Yamashita, Yawara Eguchi, Tomoaki Toyone, Kazuhisa Takahashi and Seiji Ohtori
    Citation: BMC Musculoskeletal Disorders 2011 12:144
  43. Previous research has found that acceptance of pain is more successful than cognitive coping variables for predicting adjustment to pain. This research has a limitation because measures of cognitive coping rel...

    Authors: Baltasar Rodero, Benigno Casanueva, Juan V Luciano, Margalida Gili, Antoni Serrano-Blanco and Javier García-Campayo
    Citation: BMC Musculoskeletal Disorders 2011 12:143
  44. Low-contact-stress (LCS) mobile-bearing total knee arthroplasty (TKA) (Johnson & Johnson, New Brunswick, NJ; previously: DePuy, Warsawa, USA) provides excellent functional results and wear rates in long-term f...

    Authors: Patrick Sadoghi, Andreas Leithner, Patrick Weber, Jörg Friesenbichler, Gerald Gruber, Norbert Kastner, Katrin Pohlmann, Volkmar Jansson and Bernd Wegener
    Citation: BMC Musculoskeletal Disorders 2011 12:142
  45. Patients with osteoarthritis of the knee may change their gait in an attempt to reduce loading of the affected knee, thereby reducing pain. Especially changes in lateral trunk motion may be potentially effecti...

    Authors: Martin van der Esch, Martijn PM Steultjens, Jaap Harlaar, Josien C van den Noort, Dirk L Knol and Joost Dekker
    Citation: BMC Musculoskeletal Disorders 2011 12:141
  46. Polymethylmethacrylate (PMMA) assisted ventral discectomy has been criticized for high rates of graft migration and pseudarthrosis when compared with various other fusion procedures for the treatment of cervic...

    Authors: Mario Cabraja, Daniel Koeppen, Wolfgang R Lanksch, Klaus Maier-Hauff and Stefan Kroppenstedt
    Citation: BMC Musculoskeletal Disorders 2011 12:140
  47. Shoulder pain is reported to be highly prevalent and tends to be recurrent or persistent despite medical treatment. The pathophysiological mechanisms of shoulder pain are poorly understood. Furthermore, there ...

    Authors: Carel Bron, Jan Dommerholt, Boudewijn Stegenga, Michel Wensing and Rob AB Oostendorp
    Citation: BMC Musculoskeletal Disorders 2011 12:139
  48. Although no prospective studies have compared functional results of trochanteric osteotomy and a non-trochanteric approach, most surgeons feel that trochanteric osteotomy is outdated in simple hip arthroplasty...

    Authors: Margot van der Grinten, Max Reijman, Frans C van Biezen and Jan AN Verhaar
    Citation: BMC Musculoskeletal Disorders 2011 12:138

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