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  1. Orthopaedic surgery is a high-risk specialty in which errors will undoubtedly occur. Patient safety incidents can yield valuable information to generate solutions and prevent future cases of avoidable harm. Th...

    Authors: Sukhmeet S Panesar, Andrew Carson-Stevens, Bhupinder S Mann, Mohit Bhandari and Rajan Madhok
    Citation: BMC Musculoskeletal Disorders 2012 13:93
  2. Deep infection following endoprosthetic limb reconstruction for sarcoma of the long bones is a devastating complication occurring in 15% of sarcoma patients. Optimizing infection protocols and conducting defin...

    Authors: Khaled Hasan, Antonella Racano, Benjamin Deheshi, Forough Farrokhyar, Jay Wunder, Peter Ferguson, Ginger Holt, Herbert Schwartz, Brad Petrisor, Mohit Bhandari and Michelle Ghert
    Citation: BMC Musculoskeletal Disorders 2012 13:91
  3. Few prospective cohort studies of distal upper extremity musculoskeletal disorders have been performed. Past studies have provided somewhat conflicting evidence for occupational risk factors and have largely r...

    Authors: Arun Garg, Kurt T Hegmann, Jacqueline J Wertsch, Jay Kapellusch, Matthew S Thiese, Donald Bloswick, Andrew Merryweather, Richard Sesek, Gwen Deckow-Schaefer, James Foster, Eric Wood, Richard Kendall, Xiaoming Sheng and Richard Holubkov
    Citation: BMC Musculoskeletal Disorders 2012 13:90
  4. A recently published meta-analysis comparing metallic staples to sutures in orthopaedic procedures revealed three fold increase in risk for infection in stapled wounds. The studies included in the meta-analysi...

    Authors: Jesse A Shantz, James Vernon, Jeff Leiter, Saam Morshed and Gregory Stranges
    Citation: BMC Musculoskeletal Disorders 2012 13:89
  5. Total knee arthroplasty (TKA) is often associated with a severe local inflammatory reaction which, unless controlled, leads to persistent pain up to one year after surgery. Standard and accelerated rehabilitat...

    Authors: Biagio Moretti, Angela Notarnicola, Lorenzo Moretti, Stefania Setti, Francesca De Terlizzi, Vito Pesce and Vittorio Patella
    Citation: BMC Musculoskeletal Disorders 2012 13:88
  6. Low back pain (LBP) represents a major socioeconomic burden for the Western societies. Both life-style and work-related factors may cause low back pain. Prospective cohort studies assessing risk factors among ...

    Authors: Jette Nygaard Jensen, Andreas Holtermann, Thomas Clausen, Ole Steen Mortensen, Isabella Gomes Carneiro and Lars Louis Andersen
    Citation: BMC Musculoskeletal Disorders 2012 13:87
  7. There is evidence supporting the use of extracorporeal shock wave therapy (ESWT) in calcific tendinopathy of the rotator cuff, but the best current evidence does not support its use in non-calcifying tendinopa...

    Authors: Olimpio Galasso, Ernesto Amelio, Daria Anna Riccelli and Giorgio Gasparini
    Citation: BMC Musculoskeletal Disorders 2012 13:86
  8. Physician reporting is commonly used to ascertain adverse events or outcomes measured in epidemiologic studies. However, little is known on the accuracy of physician reported malignancies compared to pertinent...

    Authors: Mark C Fisher, Victoria Furer, Marc C Hochberg, Jeffrey D Greenberg, Joel M Kremer, Jeff R Curtis, George Reed, Leslie Harrold and Daniel H Solomon
    Citation: BMC Musculoskeletal Disorders 2012 13:85
  9. The design of foot and ankle orthoses is currently limited by the methods used to fabricate the devices, particularly in terms of geometric freedom and potential to include innovative new features. Additive ma...

    Authors: Scott Telfer, Jari Pallari, Javier Munguia, Kenny Dalgarno, Martin McGeough and Jim Woodburn
    Citation: BMC Musculoskeletal Disorders 2012 13:84
  10. Retrospective assessment of surgery outcome is considered problematic. The aims of this study were to evaluate the reproducibility and accuracy of a retrospective outcome assessment of lumbar spinal stenosis s...

    Authors: Pekka Kuittinen, Timo Juhani Aalto, Tapani Heikkilä, Ville Leinonen, Sakari Savolainen, Petri Sipola, Heikki Kröger, Veli Turunen and Olavi Airaksinen
    Citation: BMC Musculoskeletal Disorders 2012 13:83
  11. Population ageing is a worldwide phenomenon that has recently challenged public healthcare systems. The knowledge of the burden of chronic musculoskeletal disorders in elders is still limited, particularly in ...

    Authors: Vivian S Miranda, Vivielle BF deCarvalho, Luciana AC Machado and João Marcos D Dias
    Citation: BMC Musculoskeletal Disorders 2012 13:82
  12. Functional treatment is a widely used and generally accepted treatment for ankle sprain. A meta-analysis comparing the different functional treatment options could not make definitive conclusions regarding the...

    Authors: Sacha Lardenoye, Ed Theunissen, Berry Cleffken, Peter RG Brink, Rob A de Bie and Martijn Poeze
    Citation: BMC Musculoskeletal Disorders 2012 13:81
  13. In the Global postural re-education (GPR) evaluation, posture alterations are associated with anterior or posterior muscular chain impairments. Our goal was to assess the reliability of the GPR muscular chain ...

    Authors: Carole Fortin, Debbie Ehrmann Feldman, Clarice Tanaka, Michelle Houde and Hubert Labelle
    Citation: BMC Musculoskeletal Disorders 2012 13:80
  14. Knowledge on the epidemiology of non-hip fractures in Spain is limited and somewhat outdated. Using computerized primary care records from the SIDIAP database, we derived age and sex-specific fracture incidenc...

    Authors: Aina Pagès-Castellà, Cristina Carbonell-Abella, Francesc Fina Avilés, Maite Alzamora, Jose Miguel Baena-Díez, Daniel Martínez Laguna, Xavier Nogués, Adolfo Díez-Pérez and Daniel Prieto-Alhambra
    Citation: BMC Musculoskeletal Disorders 2012 13:79
  15. Osteoporosis affects over 220 million people worldwide, and currently there is no ‘cure’ for the disease. Thus, there is a need to develop evidence-based, safe and acceptable prevention strategies at the popul...

    Authors: Jenny Gianoudis, Christine A Bailey, Kerrie M Sanders, Caryl A Nowson, Keith Hill, Peter R Ebeling and Robin M Daly
    Citation: BMC Musculoskeletal Disorders 2012 13:78
  16. Chronic localized pain syndromes, especially chronic low back pain (CLBP), are common reasons for consultation in general practice. In some cases chronic localized pain syndromes can appear in combination with...

    Authors: Annika Viniol, Nikita Jegan, Corinna Leonhardt, Konstantin Strauch, Markus Brugger, Jürgen Barth, Erika Baum and Annette Becker
    Citation: BMC Musculoskeletal Disorders 2012 13:77
  17. Treatment outcome of low back pain (LBP) is associated with inter-individual variations in pain relief and functional disability. Genetic variants of catechol-O-methyltransferase (COMT) gene have previously been ...

    Authors: Ahmad Omair, Benedicte Alexandra Lie, Olav Reikeras, Marit Holden and Jens Ivar Brox
    Citation: BMC Musculoskeletal Disorders 2012 13:76
  18. A major problem with rehabilitation interventions for neck pain is that the condition may have multiple causes, thus a single treatment approach is seldom efficient. The present study protocol outlines a singl...

    Authors: Martin Björklund, Mats Djupsjöbacka, Åsa Svedmark and Charlotte Häger
    Citation: BMC Musculoskeletal Disorders 2012 13:75
  19. Consumer surveys provide information on effectiveness and side effects of medical interventions in routine clinical care. A report of fibromyalgia syndrome (FMS) consumers has not been carried out in Europe.

    Authors: Winfried Häuser, Eva Jung, Brigitte Erbslöh-Möller, Mechthild Gesmann, Hedi Kühn-Becker, Franz Petermann, Jost Langhorst, Reinhard Thoma, Thomas Weiss, Frederick Wolfe and Andreas Winkelmann
    Citation: BMC Musculoskeletal Disorders 2012 13:74
  20. Studies on leisure time physical activity as risk factor or protective factor for knee or hip osteoarthritis (OA) show divergent results. Longitudinal prospective studies are needed to clarify the association ...

    Authors: Eva Ageberg, Gunnar Engström, Maria Gerhardsson de Verdier, Jan Rollof, Ewa M Roos and L Stefan Lohmander
    Citation: BMC Musculoskeletal Disorders 2012 13:73
  21. Little is known about the biomechanical effectiveness of transforaminal lumbar interbody fusion (TLIF) cages in different positioning and various posterior implants used after decompressive surgery. The use of...

    Authors: Shih-Hao Chen, Shang-Chih Lin, Wen-Chi Tsai, Chih-Wei Wang and Shih-Heng Chao
    Citation: BMC Musculoskeletal Disorders 2012 13:72
  22. Few studies demonstrate effectiveness of therapies for oral rehabilitation of patients with cerebral palsy (CP), given the difficulties in chewing, swallowing and speech, besides the intellectual, sensory and ...

    Authors: Lilian Chrystiane Giannasi, Miriam Yumi Matsui, Sandra Regina de Freitas Batista, Camila Teixeira Hardt, Carla Paes Gomes, José Benedito Oliveira Amorim, Isabella de Carvalho Aguiar, Luanda Collange, Israel dos Reis dos Santos, Ismael Souza Dias, Cláudia Santos de Oliveira, Luis Vicente Franco de Oliveira and Mônica Fernandes Gomes
    Citation: BMC Musculoskeletal Disorders 2012 13:71
  23. Physical loading leads to a deformation of bone microstructure and may influence quantitative ultrasound (QUS) parameters. This study aims at evaluating the effect of physical loading on bone QUS measurement, ...

    Authors: Cheng-Rui Liu, Hai-Jun Niu, Fang Pu, Ling Wang, Lian-Wen Sun, Yu-Bo Fan and De-Yu Li
    Citation: BMC Musculoskeletal Disorders 2012 13:70
  24. In Western Australia (WA), health policy recommends encouraging the use of active self-management strategies as part of the co-care of consumers with persistent low back pain (LBP). As many areas in WA are geo...

    Authors: Helen Slater, Andrew M Briggs, Samantha Bunzli, Stephanie J Davies, Anne J Smith and John L Quintner
    Citation: BMC Musculoskeletal Disorders 2012 13:69
  25. Severe traumatic knee injury, including injury to the anterior cruciate ligament (ACL), leads to impaired sensorimotor function. Although improvements are achieved by training, impairment often persists. Becau...

    Authors: Eva Ageberg, Anders Björkman, Birgitta Rosén and Ewa M Roos
    Citation: BMC Musculoskeletal Disorders 2012 13:68
  26. There is a lack of high quality evidence concerning the efficacy of total knee arthroplasty (TKA). According to international evidence-based guidelines, treatment of knee osteoarthritis (KOA) should include pa...

    Authors: Soren T Skou, Ewa M Roos, Mogens B Laursen, Michael S Rathleff, Lars Arendt-Nielsen, Ole H Simonsen and Sten Rasmussen
    Citation: BMC Musculoskeletal Disorders 2012 13:67
  27. Patients with knee osteoarthritis patients have problems with walking, and tend to walk slower. An important aim of knee arthroplasty is functional recovery, which should include a post-operative increase in w...

    Authors: Hamid Abbasi-Bafghi, Hamid R Fallah-Yakhdani, Onno G Meijer, Henrica CW de Vet, Sjoerd M Bruijn, Li-Yong Yang, Dirk L Knol, Barend J Van Royen and Jaap H van Dieën
    Citation: BMC Musculoskeletal Disorders 2012 13:66
  28. There is a complex interaction among acetabular component position and antetorsion of the femoral stem in determining the maximum, impingement-free prosthetic range-of-motion (ROM) in total hip arthroplasty (T...

    Authors: Tobias Renkawitz, Martin Haimerl, Lars Dohmen, Sabine Gneiting, Philipp Lechler, Michael Woerner, Hans-Robert Springorum, Markus Weber, Patrick Sussmann, Ernst Sendtner and Joachim Grifka
    Citation: BMC Musculoskeletal Disorders 2012 13:65
  29. Back pain is one of the most important causes of functional limitation, disability, and utilization of health care resources for adults of all ages, but especially among older adults. Despite the high prevalen...

    Authors: Jeffrey G Jarvik, Bryan A Comstock, Brian W Bresnahan, Srdjan S Nedeljkovic, David R Nerenz, Zoya Bauer, Andrew L Avins, Kathryn James, Judith A Turner, Patrick Heagerty, Larry Kessler, Janna L Friedly, Sean D Sullivan and Richard A Deyo
    Citation: BMC Musculoskeletal Disorders 2012 13:64
  30. The utilization of total hip replacement (THR) surgery is rapidly increasing, however few data examine whether these procedures are associated with socioeconomic status (SES) within Australia. This study exami...

    Authors: Sharon L Brennan, Tyman Stanford, Anita E Wluka, Margaret J Henry, Richard S Page, Stephen E Graves, Mark A Kotowicz, Geoffrey C Nicholson and Julie A Pasco
    Citation: BMC Musculoskeletal Disorders 2012 13:63
  31. Shoulder pain is the third most common reason for consultation with a physiotherapist and up to 26% of the general population might be expected to experience an episode at any one time. Disorders of the should...

    Authors: Chris Littlewood, Jon Ashton, Sue Mawson, Stephen May and Stephen Walters
    Citation: BMC Musculoskeletal Disorders 2012 13:62
  32. Dupuytren’s contracture (DC) is a progressive fibroproliferative disorder characterized by development of nodules and collagen cords within the palmar fascia of the hand. Collagenase clostridium histolyticum (...

    Authors: Stephen Coleman, David Gilpin, James Tursi, Greg Kaufman, Nigel Jones and Brian Cohen
    Citation: BMC Musculoskeletal Disorders 2012 13:61
  33. Osteoarthritis (OA) of the hip and knee are among the most common chronic conditions, resulting in substantial pain and functional limitations. Adequate management of OA requires a combination of medical and b...

    Authors: Kelli D Allen, Hayden B Bosworth, Dorothea S Brock, Jennifer G Chapman, Ranee Chatterjee, Cynthia J Coffman, Santanu K Datta, Rowena J Dolor, Amy S Jeffreys, Karen A Juntilla, Jennifer Kruszewski, Laurie E Marbrey, Jennifer McDuffie, Eugene Z Oddone, Nina Sperber, Mary P Sochacki…
    Citation: BMC Musculoskeletal Disorders 2012 13:60
  34. Developmental dysplasia of the hip (DDH) is a congenital or acquired deformation or misalignment of the hip joint which affects mainly females. We hypothesized that HOXD9 gene could be regulated in acetabular siz...

    Authors: Wei Tian, Lixi Zhao, Jing Wang, Peisu Suo, Jianmin Wang, Longfei Cheng, Zhi Cheng, Jian Jia, Shilian Kan, Binbin Wang and Xu Ma
    Citation: BMC Musculoskeletal Disorders 2012 13:59
  35. Pain Exposure Physical Therapy is a new treatment option for patients with Complex Regional Pain Syndrome type 1. It has been evaluated in retrospective as well as in prospective studies and proven to be safe ...

    Authors: Karlijn J Barnhoorn, Rob A B Oostendorp, Robert T M van Dongen, Frank P Klomp, Han Samwel, Gert Jan van der Wilt, Eddy Adang, Hans Groenewoud, Henk van de Meent and Jan Paul M Frölke
    Citation: BMC Musculoskeletal Disorders 2012 13:58
  36. Osteochondroma is a disease of growing bone and thus typically presents in younger patients. It has rarely been described in middle-aged and elderly patients. Data on the occurrence of osteochondroma show that...

    Authors: Jung Hyun Shim, Choon Keun Park, Seung Ho Shin, Hee Sun Jeong and Jang Hoe Hwang
    Citation: BMC Musculoskeletal Disorders 2012 13:57
  37. Metal-on-metal hip resurfacing is an alternative to metal-on-metal total hip arthroplasty, especially for young and physically active patients. However, wear which might be detected by increased serum ion leve...

    Authors: W Maurer-Ertl, J Friesenbichler, P Sadoghi, M Pechmann, M Trennheuser and A Leithner
    Citation: BMC Musculoskeletal Disorders 2012 13:56
  38. Practice guidelines recommend various types of exercise for chronic back pain but there have been few head-to-head comparisons of these interventions. General exercise seems to be an effective option for manag...

    Authors: Vesa Lehtola, Hannu Luomajoki, Ville Leinonen, Sean Gibbons and Olavi Airaksinen
    Citation: BMC Musculoskeletal Disorders 2012 13:55
  39. Cell-based approaches towards restoration of prolapsed or degenerated intervertebral discs are hampered by a lack of measures for safe administration and placement of cell suspensions within a treated disc. In...

    Authors: Karin Benz, Claudia Stippich, Claudia Osswald, Christoph Gaissmaier, Nicolas Lembert, Andreas Badke, Eric Steck, Wilhelm K Aicher and Juergen A Mollenhauer
    Citation: BMC Musculoskeletal Disorders 2012 13:54
  40. The incidence of Achilles tendinopathy is high and underlying etiology as well as biochemical and morphological pathology associated with the disease is largely unknown. The aim of the present study was to des...

    Authors: Pingel J, Fredberg U, Qvortrup K, Larsen JO, Schjerling P, Heinemeier K, Kjaer M and Langberg H
    Citation: BMC Musculoskeletal Disorders 2012 13:53
  41. Lesions located in the area of the tibial spines are rare. In most cases, treatment follows histological diagnosis, but when imaging and clinical data are considered to be "very" characteristic for benign lesi...

    Authors: Carmine Zoccali, Giuseppe Teori, Nicola Salducca, Berardino Di Paola and Ezio Adriani
    Citation: BMC Musculoskeletal Disorders 2012 13:52
  42. Like all mammalian cells, normal adult chondrocytes have a limited replicative life span, which decreases with age. To facilitate the therapeutic use of chondrocytes from older donors, a method is needed to pr...

    Authors: Masato Sato, Kazuo Shin-ya, Jeong Ik Lee, Miya Ishihara, Toshihiro Nagai, Nagatoshi Kaneshiro, Genya Mitani, Hidetoshi Tahara and Joji Mochida
    Citation: BMC Musculoskeletal Disorders 2012 13:51
  43. Osteopetrosis is a rare, inherited, bone disorder, characterized by osteosclerosis, obliteration of the medullary cavity and calcified cartilage. The autosomal dominant form is compatible with a normal life sp...

    Authors: Giovanni Manzi, Delia Romanò, Laura Moneghini and Carlo L Romanò
    Citation: BMC Musculoskeletal Disorders 2012 13:50
  44. Chronic low back pain (CLBP) experienced in middle-age may have important implications for vertebral bone health, although this issue has not been investigated as a primary aim previously. This study investiga...

    Authors: Andrew M Briggs, Leon M Straker, Angus F Burnett and John D Wark
    Citation: BMC Musculoskeletal Disorders 2012 13:49
  45. Lumbar spinal stenosis is one of the most common causes of low back pain among older adults and can cause significant disability. Despite its prevalence, treatment of spinal stenosis symptoms remains controver...

    Authors: Janna L Friedly, Brian W Bresnahan, Bryan Comstock, Judith A Turner, Richard A Deyo, Sean D Sullivan, Patrick Heagerty, Zoya Bauer, Srdjan S Nedeljkovic, Andrew L Avins, David Nerenz and Jeffrey G Jarvik
    Citation: BMC Musculoskeletal Disorders 2012 13:48
  46. The purpose was to determine the professionally-guided and self-guided medication and supplement use for joint symptom management among patients with knee and/or hip osteoarthritis (OA) in an urban hospital-ba...

    Authors: Jeffrey B Driban, Sara A Boehret, Easwaran Balasubramanian, Nicole M Cattano, Joseph Glutting and Michael R Sitler
    Citation: BMC Musculoskeletal Disorders 2012 13:47
  47. Clinical approaches like mobilization, stretching, and/or massage may decrease shoulder tightness and improve symptoms in subjects with stiff shoulders. We investigated the effect and predictors of effectivene...

    Authors: Jing-lan Yang, Shiau-yee Chen, Ching-Lin Hsieh and Jiu-jenq Lin
    Citation: BMC Musculoskeletal Disorders 2012 13:46
  48. Fracture morphology is crucial for the clinical decision-making process preceding spinal fracture treatment. The presented experimental approach was designed in order to ensure reproducibility of induced fract...

    Authors: René Hartensuer, Adam Gasch, Dominic Gehweiler, Steffen Schanz, Martin Schulze, Lars Matuszewski, Martin Langer, Michael J Raschke and Thomas Vordemvenne
    Citation: BMC Musculoskeletal Disorders 2012 13:45
  49. Bone grafts from bone banks might be mixed with bisphosphonates to inhibit the osteoclastic response. This inhibition prevents the osteoclasts to resorb the allograft bone before new bone has been formed by th...

    Authors: Nina MC Mathijssen, Gerjon Hannink, Peter Pilot, B Wim Schreurs, Rolf M Bloem and Pieter Buma
    Citation: BMC Musculoskeletal Disorders 2012 13:44
  50. Limb girdle muscular dystrophy (LGMD) type 2A is caused by mutations in the CAPN3 gene and complete lack of functional calpain 3 leads to the most severe muscle wasting. Calpain 3 is suggested to be involved i...

    Authors: Simon Hauerslev, Marie-Louise Sveen, Morten Duno, Corrado Angelini, John Vissing and Thomas O Krag
    Citation: BMC Musculoskeletal Disorders 2012 13:43

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