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  1. The 2013 Malaysian Clinical Practice Guidelines on the Management of Osteoarthritis (OA) recommend a linear step-up approach to manage knee OA. However, patients with knee OA often require a multimodal approac...

    Authors: Swan Sim Yeap, Syamsul Rizal Abu Amin, Hazlyna Baharuddin, Kar Chai Koh, Joon Kiong Lee, Verna Kar Mun Lee, Nor Hamdan Mohamad Yahaya, Cheh Chin Tai and Maw Pin Tan
    Citation: BMC Musculoskeletal Disorders 2021 22:514
  2. Although the incidence of symptomatic pulmonary thromboembolism after elective surgery for degenerative musculoskeletal disorders is comparatively low, it is extremely detrimental to both patients and health-c...

    Authors: Keigo Sato, Hideki Date, Takehiro Michikawa, Mitsuhiro Morita, Kazue Hayakawa, Shinjiro Kaneko and Nobuyuki Fujita
    Citation: BMC Musculoskeletal Disorders 2021 22:513
  3. Nonunion following treatment of supracondylar femur fractures with lateral locked plates (LLP) has been reported to be as high as 21 %. Implant related and surgeon-controlled variables have been postulated to ...

    Authors: Michael J. Weaver, George W. Chaus, Aidin Masoudi, Kaveh Momenzadeh, Amin Mohamadi, Edward K Rodriguez, Mark S. Vrahas and Ara Nazarian
    Citation: BMC Musculoskeletal Disorders 2021 22:512
  4. Prosthetic joint infection (PJI) caused by Acinetobacter baumannii (Ab) has become a growing concern due to its overwhelming ability to express resistance to antibiotics and produce biofilm.

    Authors: Raquel Bandeira da Silva, Rodrigo Otavio Araujo and Mauro José Salles
    Citation: BMC Musculoskeletal Disorders 2021 22:511
  5. Using a cage filled with local bone in anterior cervical discectomy and fusion (ACDF) can eliminate morbidities associated with autograft harvest from the iliac crest while achieving high fusion rates. However...

    Authors: Fei Ma, Shicai Xu, Yehui Liao, Qiang Tang, Chao Tang, Qing Wang and Dejun Zhong
    Citation: BMC Musculoskeletal Disorders 2021 22:510
  6. To evaluate the changes of Hounsfield units (HU) value in different types of Modic changes (MCs) and to analyze the correlation between the change of HU value and area ratio of MCs region, bone mineral density...

    Authors: Jiandong Zhu, Hao Wu, Yilei Chen, Junhui Liu, Zhi Shan, Shunwu Fan and Fengdong Zhao
    Citation: BMC Musculoskeletal Disorders 2021 22:509
  7. Upper extremity musculoskeletal disorders negatively affect ability to perform activities of daily living, self-care and work. Therefore, outcome measurements that address muscle strength, fatigue resistance, ...

    Authors: Thaís Marques Fifolato, Heloísa Correa Bueno Nardim, Ester Rodrigues do Carmo Lopes, Karen A. Kawano Suzuki, Natalia Claro da Silva, Felipe de Souza Serenza and Marisa C. Registro Fonseca
    Citation: BMC Musculoskeletal Disorders 2021 22:508
  8. Many clinical practice guidelines have been developed for the management of musculoskeletal disorders (MSDs). However, there is a gap between evidence-based knowledge and clinical practice, and reasons are poo...

    Authors: Delphine Sorondo, Cyrille Delpierre, Pierre Côté, Louis-Rachid Salmi, Christine Cedraschi, Anne Taylor-Vaisey and Nadège Lemeunier
    Citation: BMC Musculoskeletal Disorders 2021 22:507
  9. To evaluate the effect of treatment on serum bone biomarkers and explore whether serum bone biomarkers are associated with therapeutic response in rheumatoid arthritis (RA) patients treated with abatacept.

    Authors: Shin-ya Kawashiri, Yushiro Endo, Ayako Nishino, Momoko Okamoto, Sosuke Tsuji, Ayuko Takatani, Toshimasa Shimizu, Remi Sumiyoshi, Tomohiro Koga, Naoki Iwamoto, Kunihiro Ichinose, Mami Tamai, Hideki Nakamura, Tomoki Origuchi, Toshiyuki Aramaki, Yukitaka Ueki…
    Citation: BMC Musculoskeletal Disorders 2021 22:506
  10. Although Oxford unicompartmental knee arthroplasty (UKA) is used in patients of wide age ranges, there is no clear information regarding the age differences in terms of intraoperative femorotibial rotational k...

    Authors: Kohei Kawaguchi, Hiroshi Inui, Shuji Taketomi, Ryota Yamagami, Kenichi Kono, Shin Sameshima, Tomofumi Kage and Sakae Tanaka
    Citation: BMC Musculoskeletal Disorders 2021 22:505
  11. Intraoperative hypothermia is associated with various risk factors, morbidity, and mortality in patients undergoing total knee arthroplasty (TKA), increasing the emotional and financial burden on patients. Thi...

    Authors: Ronika Devi Ukrani, Aiman Arif, Anum Sadruddin, Obada Hasan and Shahryar Noordin
    Citation: BMC Musculoskeletal Disorders 2021 22:504
  12. Hallux valgus deformity has been reported to be associated with increased postural sway. However, the direction and magnitude of postural sway associated with hallux valgus remain inconclusive. We assessed the...

    Authors: Hiroaki Omae, Takashi Ohsawa, Naohiro Hio, Kazuhiko Tsunoda, Takuya Omodaka, Shogo Hashimoto, Akira Ueno, Tsuyoshi Tajika, Yoichi Iizuka and Hirotaka Chikuda
    Citation: BMC Musculoskeletal Disorders 2021 22:503
  13. Open wedge high tibial osteotomy (OWHTO) is an effective treatment option for young and middle-aged active patients with medial unicompartmental knee osteoarthritis (OA). In addition, particulated cartilage im...

    Authors: Yasushi Oshima, Norishige Iizawa, Shinro Takai and Tokifumi Majima
    Citation: BMC Musculoskeletal Disorders 2021 22:502
  14. Osteoarthritis (OA) is a leading cause of disability and pain especially among older adults, but it is also known to affect working age individuals, often leading to reduced productivity and increased healthca...

    Authors: Milla Summanen, Liisa Ukkola-Vuoti, Samu Kurki, Samuli Tuominen and Rami Madanat
    Citation: BMC Musculoskeletal Disorders 2021 22:501
  15. The long-term effects of behavioural medical rehabilitation (BMR), as a type of multidisciplinary rehabilitation, in the treatment of chronic non-specific low back pain (CLBP) have been shown. However, the spe...

    Authors: Jana Semrau, Christian Hentschke, Stefan Peters and Klaus Pfeifer
    Citation: BMC Musculoskeletal Disorders 2021 22:500
  16. Surgical treatment of full-thickness rotator cuff (RC) tears is associated with generally good results. There is no consensus regarding treatment of partial thickness tears that fail conservative treatment. Th...

    Authors: Chadwick C Prodromos, Susan Finkle, Alexandra Prodromos, Jasmine Li Chen, Aron Schwartz and Lucas Wathen
    Citation: BMC Musculoskeletal Disorders 2021 22:499
  17. The interference screw is the most popular device that fixes the graft for anterior cruciate ligament reconstruction, reducing the incidence of windshield effect and bungee effect. For the screw, either metall...

    Authors: Chao-Hua Fang, Ming Li, Yun-Feng Zhang and Hua Liu
    Citation: BMC Musculoskeletal Disorders 2021 22:498
  18. Lag screw cut-out is the most common cause of fixation failure of trochanteric fractures. Intraoperative assessment of fracture reduction and fixation quality is vital to avoid fracture reduction and achieve g...

    Authors: Wei Hao, Long Fang, Shuangshuang Yin, Yongjie Lin and Bingchen Wang
    Citation: BMC Musculoskeletal Disorders 2021 22:497
  19. We compared blood loss and transfusion frequency between the lateral decubitus and the supine position in patients undergoing hip replacement surgery due to femoral neck fractures.

    Authors: Thomas Haider, Jesse Seilern und Aspang, Claudia Gahleitner, Stefan Plesser and Stefan Hajdu
    Citation: BMC Musculoskeletal Disorders 2021 22:496
  20. Total hip arthroplasty (THA) candidates frequently present pelvic malrotation. The aim of this study is to analyze how pelvic malrotation influence transverse acetabular ligament (TAL) guided cup orientation a...

    Authors: Tingxian Ling, Zichuan Ding, Mingcheng Yuan, Kai Zhou and Zongke Zhou
    Citation: BMC Musculoskeletal Disorders 2021 22:495
  21. Macrophages and inflammatory cytokines play important roles in bone fracture healing. However, the expression patterns of macrophages and inflammatory cytokines during fracture healing under the condition of p...

    Authors: Lin Chen, Shao Cheng, Kanghui Sun, Jing Wang, Xinhua Liu, Yongjian Zhao, Junjie Yang, Dongfeng Zhao, Chunchun Xue, Yuren Tao, Shitian Zhao, Hao Zhang, Sheng Lu, Qi Shi, Yongjun Wang and Bing Shu
    Citation: BMC Musculoskeletal Disorders 2021 22:494
  22. Re-injury rates following reconstruction of the anterior cruciate ligament (ACL) are significant; in more than 20% of patients a rupture of the graft occurs. One of the main reasons for graft failure is malpos...

    Authors: M. J. M. Zee, R. A. Sulaihem, R. L. Diercks and I. van den Akker-Scheek
    Citation: BMC Musculoskeletal Disorders 2021 22:493
  23. Previous studies have demonstrated the efficacy of duloxetine in reducing postoperative pain and opioid consumption. However, the effect of duloxetine on total hip arthroplasty (THA) remains unclear. The objec...

    Authors: Hao Li, Wei-Nan Zeng, Zi-Chuan Ding, Ming-Cheng Yuan, Yong-Rui Cai and Zong-Ke Zhou
    Citation: BMC Musculoskeletal Disorders 2021 22:492
  24. Difficulty in obtaining union, recurrent fractures, and residual deformities remain the problems challenging the management of congenital pseudarthrosis of the tibia (CPT). We applied the “Eiffel Tower” double...

    Authors: Xiaoyu Wang, Li Shi, Rui Zhang, Wenbo Wang, Feng Wang, Mengwei Wang, Ze Xu, Rongtai Zuo, Jia Xu and Qinglin Kang
    Citation: BMC Musculoskeletal Disorders 2021 22:490
  25. Survival analysis and effect of covariates on survival time is a central research interest. Cox proportional hazards regression remains as a gold standard in the survival analysis. The Cox model relies on the ...

    Authors: Ilari Kuitunen, Ville T. Ponkilainen, Mikko M. Uimonen, Antti Eskelinen and Aleksi Reito
    Citation: BMC Musculoskeletal Disorders 2021 22:489
  26. Clubfeet are typically shorter than normal feet. This study aimed first to describe the development of foot length in a consecutive series of children with congenital clubfoot and second to relate foot length ...

    Authors: Evgenia Manousaki, Anna-Clara Esbjörnsson, Gunnar Hägglund and Hanneke Andriesse
    Citation: BMC Musculoskeletal Disorders 2021 22:487
  27. Femoral posterior condylar offset (PCO) and posterior tibial slope (PTS) are important for postoperative range of motion after total knee arthroplasty (TKA). However, normative data of PCO and PTS and the corr...

    Authors: Liangxiao Bao, Shengwei Rong, Zhanjun Shi, Jian Wang and Yang Zhang
    Citation: BMC Musculoskeletal Disorders 2021 22:486
  28. The purpose of this study was to determine the effect of targeted eccentric calf muscle exercises compared to regular training on ankle dorsiflexion in healthy adolescent soccer players with a decreased ankle ...

    Authors: Iris Femmigje Lagas, Duncan E. Meuffels, Edwin Visser, Floor P. Groot, Max Reijman, Jan A.N. Verhaar and Robert-Jan de Vos
    Citation: BMC Musculoskeletal Disorders 2021 22:485
  29. Conservative therapies are typically offered to individuals who experience mild or intermittent symptoms of carpal tunnel syndrome (CTS) or postoperatively to subjects who have undergone carpal tunnel release....

    Authors: Juhani Multanen, Mikko M. Uimonen, Jussi P. Repo, Arja Häkkinen and Jari Ylinen
    Citation: BMC Musculoskeletal Disorders 2021 22:484
  30. Adult non-degenerative scoliosis accounts for 90% of spinal deformities in young adults. However, perioperative complications and related risk factors of long posterior instrumentation and fusion for the treat...

    Authors: Nan Wu, Jiashen Shao, Zhen Zhang, Shengru Wang, Ziquan Li, Sen Zhao, Yang Yang, Lian Liu, Chenxi Yu, Sen Liu, Zhengye Zhao, You Du, Yuanqiang Zhang, Lianlei Wang, Yu Zhao, Keyi Yu…
    Citation: BMC Musculoskeletal Disorders 2021 22:483
  31. Hip arthroplasty using acrylic prosthesis was once conducted; however, it has now been abandoned because of early breakages and wear of material. Therefore, complications or revision surgeries due to the use o...

    Authors: Hisatoshi Ishikura, Masaki Nakamura, Kenta Matsuda, Takeyuki Tanaka, Hirotaka Kawano and Sakae Tanaka
    Citation: BMC Musculoskeletal Disorders 2021 22:482
  32. Indications and cutoff value of deformities to determine surgical procedures for flexed knee gait are not clear. The aim was to determine the influence of none or mild, and moderate preoperative knee flexion c...

    Authors: Evelina Pantzar-Castilla, Brian Po-Jung Chen, Freeman Miller and Jacques Riad
    Citation: BMC Musculoskeletal Disorders 2021 22:481
  33. Wnt-catenin signaling antagonists sclerostin and dickkopf-related protein-1 (Dkk-1) inhibit bone formation and are involved in the pathogenesis of postmenopausal osteoporosis (PO). However, the association bet...

    Authors: Jia Peng, Zhang Dong, Zhang Hui, Wang Aifei, Deng Lianfu and Xu Youjia
    Citation: BMC Musculoskeletal Disorders 2021 22:480
  34. We report a case of osteitis fibrosa cystica, a rare benign resorptive bone lesion caused by hyperparathyroidism, that presented on imaging as an aggressive bone tumor.

    Authors: Maya L. Nasser, Serge Medawar, Tonine Younan, Halim Abboud and Viviane Trak-Smayra
    Citation: BMC Musculoskeletal Disorders 2021 22:479
  35. Dislocation after primary total hip arthroplasty (THA) has an incidence of 2–3%. Approximately 77% of dislocations occur within the first year after surgery. The SuperPATH technique is a minimally invasive app...

    Authors: Andrew Kay, Derek Klavas, Varan Haghshenas, Mimi Phan and Daniel Le
    Citation: BMC Musculoskeletal Disorders 2021 22:478
  36. Reduced gliding ability of the median nerve in the carpal tunnel has been observed in patients with carpal tunnel syndrome (CTS). The purpose of this study was to evaluate the gliding abilities of the median n...

    Authors: Chien-Ting Liu, Dung-Huan Liu, Chii-Jen Chen, You-Wei Wang, Pao-Sheng Wu and Yi-Shiung Horng
    Citation: BMC Musculoskeletal Disorders 2021 22:477
  37. Vertebral compression fractures (VCFs) are the most common among all osteoporotic fractures. The body may compensate to the kyphosis from vertebral compression fractures with lordosis of the adjacent spinal se...

    Authors: Leo Tsz Ching Chau, Zongshan Hu, Koko Shaau Yiu Ko, Gene Chi Wai Man, Kwong Hang Yeung, Ying Yeung Law, Lawrence Chun Man Lau, Ronald Man Yeung Wong, Winnie Chiu Wing Chu, Jack Chun Yiu Cheng and Sheung Wai Law
    Citation: BMC Musculoskeletal Disorders 2021 22:476
  38. In clinical trials, good quality athletic shoes offer short-term improvements (two-months) in foot pain and disability in people with gout, but these improvements are not sustained over time. This may be due t...

    Authors: Mike Frecklington, Nicola Dalbeth, Peter McNair, Alain Vandal, Peter Gow and Keith Rome
    Citation: BMC Musculoskeletal Disorders 2021 22:475
  39. Fibrinogen (FIB) has been found to be a promising marker in diagnosing periprosthetic joint infection (PJI), however, the value of FIB in predicting reinfection of PJI is unknown. The purpose of this study was...

    Authors: Dacheng Zhao, Jinwen He, Xingwen Wang, Xiaobing Zhao, Yayi Xia and Bin Geng
    Citation: BMC Musculoskeletal Disorders 2021 22:474
  40. Low back pain is often long-lasting, and implementation of low-cost interventions to improve care and minimise its burden is needed. GLA:D® Back is an evidence-based programme consisting of patient education a...

    Authors: Inge Ris, Daniel Broholm, Jan Hartvigsen, Tonny Elmose Andersen and Alice Kongsted
    Citation: BMC Musculoskeletal Disorders 2021 22:473
  41. Exercise is a common approach for the management of patients with chronic non-specific low back pain (LBP). However, there is no clear mechanistic evidence or consensus on what type of exercise is more effecti...

    Authors: Maryse Fortin, Meaghan Rye, Alexa Roussac, Neda Naghdi, Luciana Gazzi Macedo, Geoffrey Dover, James M. Elliott, Richard DeMont, Michael H. Weber and Véronique Pepin
    Citation: BMC Musculoskeletal Disorders 2021 22:472
  42. Opioids continue to be the analgesic of choice for postoperative pain control following arthroscopic knee and shoulder surgery. Despite their widespread use, there are limited evidence-based clinical practice ...

    Authors:
    Citation: BMC Musculoskeletal Disorders 2021 22:471

    The Correction to this article has been published in BMC Musculoskeletal Disorders 2021 22:615

  43. Neuromuscular and quadriceps exercises have been shown to be effective approaches to relieve pain and to improve function for patients with knee osteoarthritis. In this study, we aim to provide an informative ...

    Authors: Lin Wang, Suhang Xie, Tianjie Bao, Siyi Zhu, Qiu Liang, Xiaoyi Wang, Ruishi Zhang, Xiaona Xiang, Chunping Du and Chengqi He
    Citation: BMC Musculoskeletal Disorders 2021 22:470
  44. Osteomyelitis (OM) in the jaw is an inflammatory disease of osseous tissue that begins in the medullary space and progressively expands to the cortical portion of the bone, the Haversian system, the periosteum...

    Authors: Buyanbileg Sodnom-Ish, Mi Young Eo, Mi Hyun Seo, Jong Ho Lee and Soung Min Kim
    Citation: BMC Musculoskeletal Disorders 2021 22:469
  45. Failure of surgical fixation in orthopaedic fractures occurs at a significantly higher rate in osteoporotic patients due to weakened osteoporotic bone. A therapy to acutely improve the mechanical properties of...

    Authors: Michael R. Eby, Danielle M. Cristino, Matthew Counihan, Kendall M. Masada, Jaimo Ahn and Michael W. Hast
    Citation: BMC Musculoskeletal Disorders 2021 22:468
  46. The Nice knots have been widely used in orthopedic surgeries to fix torn soft tissue and fracture in recent years. The study aims to investigate the clinical efficacy and prognosis of intraoperative and postop...

    Authors: Fangning Hu, Xi Liu, Fanxiao Liu, Honglei Jia, Xiaolong Lv, Fengrui Wang, Shihong Xu, Juanjuan Yang, Lingfei Hu, Bomin Wang and Yongliang Yang
    Citation: BMC Musculoskeletal Disorders 2021 22:467
  47. Limitations in spinal mobility are a characteristic feature of Axial Spondyloarthritis. Current clinical measurements of spinal mobility have shown low criterion-concurrent validity. This study sought to evalu...

    Authors: John Charles Snow, Kyle Simpson, Proton Rahman, Samuel Howarth and Diana De Carvalho
    Citation: BMC Musculoskeletal Disorders 2021 22:464

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