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  1. Juvenile dermatomyositis (JDM) is a rare, often chronic, systemic autoimmune disease of childhood, characterized by inflammation of the microvasculature of the skeletal muscle and skin. Prominent clinical feat...

    Authors: Esther A Habers, Marco van Brussel, Anneli C Langbroek-Amersfoort, Annet van Royen-Kerkhof and Tim Takken
    Citation: BMC Musculoskeletal Disorders 2012 13:108
    Content type: Study protocol Published on:

  2. IL-6 is a pleiotropic cytokine that modulates inflammatory responses and plays critical roles in muscle maintenance and remodeling. In the mouse model (mdx) of Duchenne Muscular Dystrophy, IL-6 and muscle inflamm...

    Authors: Matthew C Kostek, Kanneboyina Nagaraju, Emidio Pistilli, Arpana Sali, San-Huei Lai, Brad Gordon and Yi-Wen Chen
    Citation: BMC Musculoskeletal Disorders 2012 13:106
    Content type: Research article Published on:

  3. Epimedii herba is one of the most frequently used herbs in formulas that are prescribed for the treatment of osteoporosis in China and its main constituent is Epimedium pubescen flavonoid (EPF). However, it is u...

    Authors: Shu-guang Gao, Ling Cheng, Kang-hua Li, Wen-He Liu, Mai Xu, Wei Jiang, Li-Cheng Wei, Fang-jie Zhang, Wen-feng Xiao, Yi-lin Xiong, Jian Tian, Chao Zeng, Jin-peng Sun, Qiang Xie and Guang-hua Lei
    Citation: BMC Musculoskeletal Disorders 2012 13:105
    Content type: Research article Published on:

  4. Physical activity and exercise therapy are among the accepted clinical rehabilitation guidelines and are recommended self-management strategies for chronic low back pain. However, many back pain sufferers do n...

    Authors: Chris Lonsdale, Amanda M Hall, Geoffrey C Williams, Suzanne M McDonough, Nikos Ntoumanis, Aileen Murray and Deirdre A Hurley
    Citation: BMC Musculoskeletal Disorders 2012 13:104
    Content type: Study protocol Published on:

  5. Idiopathic inflammatory myopathies (IIMs) are a rare group of autoimmune syndromes characterized by chronic muscle inflammation and muscle weakness with no known cause. Little is known about their incidence an...

    Authors: Karen E Smoyer-Tomic, Anthony A Amato and Ancilla W Fernandes
    Citation: BMC Musculoskeletal Disorders 2012 13:103
    Content type: Research article Published on:

  6. Polymyalgia Rheumatica (PMR) is the commonest inflammatory condition seen in older patients in primary care. To date, however, research has been focused on secondary care cohorts rather than primary care where...

    Authors: Sara Muller, Samantha Hider, Toby Helliwell, Joanne Bailey, Kevin Barraclough, Louise Cope, Bhaskar Dasgupta, Rebecca Foskett, Rhian Hughes, Zoe Mayson, Charlotte Purcell, Edward Roddy, Simon Wathall, Irena Zwierska and Christian D Mallen
    Citation: BMC Musculoskeletal Disorders 2012 13:102
    Content type: Study protocol Published on:

  7. The gluteus medius muscle is essential for gait and hip stability. Changes that occur in the gluteus medius muscles in patients with developmental dysplasia of the hip (DDH) are not well understood. A better u...

    Authors: RuiYu Liu, XiaoDong Wen, ZhiQin Tong, KunZheng Wang and ChunSheng Wang
    Citation: BMC Musculoskeletal Disorders 2012 13:101
    Content type: Research article Published on:

  8. Hmg-CoA reductase inhibitors (statins) are widely used to prevent disease associated with vascular disease and hyperlipidemia. Although side effects are uncommon, clinical observations suggest statin exposure ...

    Authors: Beth B Murinson, Norman J Haughey and Nicholas J Maragakis
    Citation: BMC Musculoskeletal Disorders 2012 13:100
    Content type: Research article Published on:

  9. The purpose of this study was to test the hypothesis that direct vertebral derotation by pedicle screws (PS) causes hypokyphosis of the thoracic spine in adolescent idiopathic scoliosis (AIS) patients, using c...

    Authors: Kota Watanabe, Takayuki Nakamura, Akio Iwanami, Naobumi Hosogane, Takashi Tsuji, Ken Ishii, Masaya Nakamura, Yoshiaki Toyama, Kazuhiro Chiba and Morio Matsumoto
    Citation: BMC Musculoskeletal Disorders 2012 13:99
    Content type: Research article Published on:

  10. Although musculoskeletal disorders (MSD) are among the most prevalent chronic conditions, minimal attention has been paid to the paediatric population. The aim of this study is to describe the annual prevalenc...

    Authors: Anna C Gunz, Mayilee Canizares, Crystal MacKay and Elizabeth M Badley
    Citation: BMC Musculoskeletal Disorders 2012 13:98
    Content type: Research article Published on:

  11. Hydroxyapatite (HA) coatings composed with bisphosphonates (BPs) which have high mineral-binding affinities have been confirmed to successfully enhance implant stability. However, few previous studies focused ...

    Authors: Shun Niu, Xiaorui Cao, Yan Zhang, Qingsheng Zhu, Jinyu Zhu and Ping Zhen
    Citation: BMC Musculoskeletal Disorders 2012 13:97
    Content type: Research article Published on:

  12. Work disability is common among women with fibromyalgia (FM). The aim of the study was to investigate what health problems and work-related difficulties lead to hinders for continued work among women with FM.

    Authors: Kaisa Mannerkorpi and Gunvor Gard
    Citation: BMC Musculoskeletal Disorders 2012 13:96
    Content type: Research article Published on:

  13. Leg length inequality (LLI) was identified as a problem of total hip arthroplasty soon after its introduction. Leg lengthening is the most common form of LLI. Possible consequences are limping, neuronal dysfun...

    Authors: Christoph Röder, Raphael Vogel, Lukas Burri, Daniel Dietrich and Lukas P Staub
    Citation: BMC Musculoskeletal Disorders 2012 13:95
    Content type: Research article Published on:

  14. It has been indicated that moderate or high dose of X-irradiation could delay fracture union and cause osteoradionecrosis, in part, mediated by its effect on proliferation and differentiation of osteoblasts. H...

    Authors: Wei Xu, Lan Xu, Ming Chen, Yong Tao Mao, Zong Gang Xie, Shi Liang Wu and Qi Rong Dong
    Citation: BMC Musculoskeletal Disorders 2012 13:94
    Content type: Research article Published on:

  15. Orthopaedic surgery is a high-risk specialty in which errors will undoubtedly occur. Patient safety incidents can yield valuable information to generate solutions and prevent future cases of avoidable harm. Th...

    Authors: Sukhmeet S Panesar, Andrew Carson-Stevens, Bhupinder S Mann, Mohit Bhandari and Rajan Madhok
    Citation: BMC Musculoskeletal Disorders 2012 13:93
    Content type: Research article Published on:

  16. Despite potential benefits, some patients decide not to use their custom-made orthopaedic shoes (OS). Factors are known in the domains ‘usability’, ‘communication and service’, and ‘opinion of others’ that inf...

    Authors: Jaap J van Netten, Pieter U Dijkstra, Jan H B Geertzen and Klaas Postema
    Citation: BMC Musculoskeletal Disorders 2012 13:92
    Content type: Research article Published on:

  17. Deep infection following endoprosthetic limb reconstruction for sarcoma of the long bones is a devastating complication occurring in 15% of sarcoma patients. Optimizing infection protocols and conducting defin...

    Authors: Khaled Hasan, Antonella Racano, Benjamin Deheshi, Forough Farrokhyar, Jay Wunder, Peter Ferguson, Ginger Holt, Herbert Schwartz, Brad Petrisor, Mohit Bhandari and Michelle Ghert
    Citation: BMC Musculoskeletal Disorders 2012 13:91
    Content type: Research article Published on:

  18. Few prospective cohort studies of distal upper extremity musculoskeletal disorders have been performed. Past studies have provided somewhat conflicting evidence for occupational risk factors and have largely r...

    Authors: Arun Garg, Kurt T Hegmann, Jacqueline J Wertsch, Jay Kapellusch, Matthew S Thiese, Donald Bloswick, Andrew Merryweather, Richard Sesek, Gwen Deckow-Schaefer, James Foster, Eric Wood, Richard Kendall, Xiaoming Sheng and Richard Holubkov
    Citation: BMC Musculoskeletal Disorders 2012 13:90
    Content type: Study protocol Published on:

  19. A recently published meta-analysis comparing metallic staples to sutures in orthopaedic procedures revealed three fold increase in risk for infection in stapled wounds. The studies included in the meta-analysi...

    Authors: Jesse A Shantz, James Vernon, Jeff Leiter, Saam Morshed and Gregory Stranges
    Citation: BMC Musculoskeletal Disorders 2012 13:89
    Content type: Study protocol Published on:

  20. Total knee arthroplasty (TKA) is often associated with a severe local inflammatory reaction which, unless controlled, leads to persistent pain up to one year after surgery. Standard and accelerated rehabilitat...

    Authors: Biagio Moretti, Angela Notarnicola, Lorenzo Moretti, Stefania Setti, Francesca De Terlizzi, Vito Pesce and Vittorio Patella
    Citation: BMC Musculoskeletal Disorders 2012 13:88
    Content type: Research article Published on:

  21. Low back pain (LBP) represents a major socioeconomic burden for the Western societies. Both life-style and work-related factors may cause low back pain. Prospective cohort studies assessing risk factors among ...

    Authors: Jette Nygaard Jensen, Andreas Holtermann, Thomas Clausen, Ole Steen Mortensen, Isabella Gomes Carneiro and Lars Louis Andersen
    Citation: BMC Musculoskeletal Disorders 2012 13:87
    Content type: Research article Published on:

  22. There is evidence supporting the use of extracorporeal shock wave therapy (ESWT) in calcific tendinopathy of the rotator cuff, but the best current evidence does not support its use in non-calcifying tendinopa...

    Authors: Olimpio Galasso, Ernesto Amelio, Daria Anna Riccelli and Giorgio Gasparini
    Citation: BMC Musculoskeletal Disorders 2012 13:86
    Content type: Research article Published on:

  23. Physician reporting is commonly used to ascertain adverse events or outcomes measured in epidemiologic studies. However, little is known on the accuracy of physician reported malignancies compared to pertinent...

    Authors: Mark C Fisher, Victoria Furer, Marc C Hochberg, Jeffrey D Greenberg, Joel M Kremer, Jeff R Curtis, George Reed, Leslie Harrold and Daniel H Solomon
    Citation: BMC Musculoskeletal Disorders 2012 13:85
    Content type: Research article Published on:

  24. The design of foot and ankle orthoses is currently limited by the methods used to fabricate the devices, particularly in terms of geometric freedom and potential to include innovative new features. Additive ma...

    Authors: Scott Telfer, Jari Pallari, Javier Munguia, Kenny Dalgarno, Martin McGeough and Jim Woodburn
    Citation: BMC Musculoskeletal Disorders 2012 13:84
    Content type: Technical advance Published on:

  25. Retrospective assessment of surgery outcome is considered problematic. The aims of this study were to evaluate the reproducibility and accuracy of a retrospective outcome assessment of lumbar spinal stenosis s...

    Authors: Pekka Kuittinen, Timo Juhani Aalto, Tapani Heikkilä, Ville Leinonen, Sakari Savolainen, Petri Sipola, Heikki Kröger, Veli Turunen and Olavi Airaksinen
    Citation: BMC Musculoskeletal Disorders 2012 13:83
    Content type: Research article Published on:

  26. Population ageing is a worldwide phenomenon that has recently challenged public healthcare systems. The knowledge of the burden of chronic musculoskeletal disorders in elders is still limited, particularly in ...

    Authors: Vivian S Miranda, Vivielle BF deCarvalho, Luciana AC Machado and João Marcos D Dias
    Citation: BMC Musculoskeletal Disorders 2012 13:82
    Content type: Research article Published on:

  27. Functional treatment is a widely used and generally accepted treatment for ankle sprain. A meta-analysis comparing the different functional treatment options could not make definitive conclusions regarding the...

    Authors: Sacha Lardenoye, Ed Theunissen, Berry Cleffken, Peter RG Brink, Rob A de Bie and Martijn Poeze
    Citation: BMC Musculoskeletal Disorders 2012 13:81
    Content type: Research article Published on:

  28. In the Global postural re-education (GPR) evaluation, posture alterations are associated with anterior or posterior muscular chain impairments. Our goal was to assess the reliability of the GPR muscular chain ...

    Authors: Carole Fortin, Debbie Ehrmann Feldman, Clarice Tanaka, Michelle Houde and Hubert Labelle
    Citation: BMC Musculoskeletal Disorders 2012 13:80
    Content type: Research article Published on:

  29. Knowledge on the epidemiology of non-hip fractures in Spain is limited and somewhat outdated. Using computerized primary care records from the SIDIAP database, we derived age and sex-specific fracture incidenc...

    Authors: Aina Pagès-Castellà, Cristina Carbonell-Abella, Francesc Fina Avilés, Maite Alzamora, Jose Miguel Baena-Díez, Daniel Martínez Laguna, Xavier Nogués, Adolfo Díez-Pérez and Daniel Prieto-Alhambra
    Citation: BMC Musculoskeletal Disorders 2012 13:79
    Content type: Research article Published on:

  30. Osteoporosis affects over 220 million people worldwide, and currently there is no ‘cure’ for the disease. Thus, there is a need to develop evidence-based, safe and acceptable prevention strategies at the popul...

    Authors: Jenny Gianoudis, Christine A Bailey, Kerrie M Sanders, Caryl A Nowson, Keith Hill, Peter R Ebeling and Robin M Daly
    Citation: BMC Musculoskeletal Disorders 2012 13:78
    Content type: Study protocol Published on:

  31. Chronic localized pain syndromes, especially chronic low back pain (CLBP), are common reasons for consultation in general practice. In some cases chronic localized pain syndromes can appear in combination with...

    Authors: Annika Viniol, Nikita Jegan, Corinna Leonhardt, Konstantin Strauch, Markus Brugger, Jürgen Barth, Erika Baum and Annette Becker
    Citation: BMC Musculoskeletal Disorders 2012 13:77
    Content type: Study protocol Published on:

  32. Treatment outcome of low back pain (LBP) is associated with inter-individual variations in pain relief and functional disability. Genetic variants of catechol-O-methyltransferase (COMT) gene have previously been ...

    Authors: Ahmad Omair, Benedicte Alexandra Lie, Olav Reikeras, Marit Holden and Jens Ivar Brox
    Citation: BMC Musculoskeletal Disorders 2012 13:76
    Content type: Research article Published on:

  33. A major problem with rehabilitation interventions for neck pain is that the condition may have multiple causes, thus a single treatment approach is seldom efficient. The present study protocol outlines a singl...

    Authors: Martin Björklund, Mats Djupsjöbacka, Åsa Svedmark and Charlotte Häger
    Citation: BMC Musculoskeletal Disorders 2012 13:75
    Content type: Study protocol Published on:

  34. Consumer surveys provide information on effectiveness and side effects of medical interventions in routine clinical care. A report of fibromyalgia syndrome (FMS) consumers has not been carried out in Europe.

    Authors: Winfried Häuser, Eva Jung, Brigitte Erbslöh-Möller, Mechthild Gesmann, Hedi Kühn-Becker, Franz Petermann, Jost Langhorst, Reinhard Thoma, Thomas Weiss, Frederick Wolfe and Andreas Winkelmann
    Citation: BMC Musculoskeletal Disorders 2012 13:74
    Content type: Research article Published on:

  35. Studies on leisure time physical activity as risk factor or protective factor for knee or hip osteoarthritis (OA) show divergent results. Longitudinal prospective studies are needed to clarify the association ...

    Authors: Eva Ageberg, Gunnar Engström, Maria Gerhardsson de Verdier, Jan Rollof, Ewa M Roos and L Stefan Lohmander
    Citation: BMC Musculoskeletal Disorders 2012 13:73
    Content type: Research article Published on:

  36. Little is known about the biomechanical effectiveness of transforaminal lumbar interbody fusion (TLIF) cages in different positioning and various posterior implants used after decompressive surgery. The use of...

    Authors: Shih-Hao Chen, Shang-Chih Lin, Wen-Chi Tsai, Chih-Wei Wang and Shih-Heng Chao
    Citation: BMC Musculoskeletal Disorders 2012 13:72
    Content type: Research article Published on:

  37. Few studies demonstrate effectiveness of therapies for oral rehabilitation of patients with cerebral palsy (CP), given the difficulties in chewing, swallowing and speech, besides the intellectual, sensory and ...

    Authors: Lilian Chrystiane Giannasi, Miriam Yumi Matsui, Sandra Regina de Freitas Batista, Camila Teixeira Hardt, Carla Paes Gomes, José Benedito Oliveira Amorim, Isabella de Carvalho Aguiar, Luanda Collange, Israel dos Reis dos Santos, Ismael Souza Dias, Cláudia Santos de Oliveira, Luis Vicente Franco de Oliveira and Mônica Fernandes Gomes
    Citation: BMC Musculoskeletal Disorders 2012 13:71
    Content type: Study protocol Published on:

  38. Physical loading leads to a deformation of bone microstructure and may influence quantitative ultrasound (QUS) parameters. This study aims at evaluating the effect of physical loading on bone QUS measurement, ...

    Authors: Cheng-Rui Liu, Hai-Jun Niu, Fang Pu, Ling Wang, Lian-Wen Sun, Yu-Bo Fan and De-Yu Li
    Citation: BMC Musculoskeletal Disorders 2012 13:70
    Content type: Research article Published on:

  39. In Western Australia (WA), health policy recommends encouraging the use of active self-management strategies as part of the co-care of consumers with persistent low back pain (LBP). As many areas in WA are geo...

    Authors: Helen Slater, Andrew M Briggs, Samantha Bunzli, Stephanie J Davies, Anne J Smith and John L Quintner
    Citation: BMC Musculoskeletal Disorders 2012 13:69
    Content type: Research article Published on:

  40. Severe traumatic knee injury, including injury to the anterior cruciate ligament (ACL), leads to impaired sensorimotor function. Although improvements are achieved by training, impairment often persists. Becau...

    Authors: Eva Ageberg, Anders Björkman, Birgitta Rosén and Ewa M Roos
    Citation: BMC Musculoskeletal Disorders 2012 13:68
    Content type: Research article Published on:

  41. There is a lack of high quality evidence concerning the efficacy of total knee arthroplasty (TKA). According to international evidence-based guidelines, treatment of knee osteoarthritis (KOA) should include pa...

    Authors: Soren T Skou, Ewa M Roos, Mogens B Laursen, Michael S Rathleff, Lars Arendt-Nielsen, Ole H Simonsen and Sten Rasmussen
    Citation: BMC Musculoskeletal Disorders 2012 13:67
    Content type: Study protocol Published on:

  42. Patients with knee osteoarthritis patients have problems with walking, and tend to walk slower. An important aim of knee arthroplasty is functional recovery, which should include a post-operative increase in w...

    Authors: Hamid Abbasi-Bafghi, Hamid R Fallah-Yakhdani, Onno G Meijer, Henrica CW de Vet, Sjoerd M Bruijn, Li-Yong Yang, Dirk L Knol, Barend J Van Royen and Jaap H van Dieën
    Citation: BMC Musculoskeletal Disorders 2012 13:66
    Content type: Research article Published on:

  43. There is a complex interaction among acetabular component position and antetorsion of the femoral stem in determining the maximum, impingement-free prosthetic range-of-motion (ROM) in total hip arthroplasty (T...

    Authors: Tobias Renkawitz, Martin Haimerl, Lars Dohmen, Sabine Gneiting, Philipp Lechler, Michael Woerner, Hans-Robert Springorum, Markus Weber, Patrick Sussmann, Ernst Sendtner and Joachim Grifka
    Citation: BMC Musculoskeletal Disorders 2012 13:65
    Content type: Research article Published on:

  44. Back pain is one of the most important causes of functional limitation, disability, and utilization of health care resources for adults of all ages, but especially among older adults. Despite the high prevalen...

    Authors: Jeffrey G Jarvik, Bryan A Comstock, Brian W Bresnahan, Srdjan S Nedeljkovic, David R Nerenz, Zoya Bauer, Andrew L Avins, Kathryn James, Judith A Turner, Patrick Heagerty, Larry Kessler, Janna L Friedly, Sean D Sullivan and Richard A Deyo
    Citation: BMC Musculoskeletal Disorders 2012 13:64
    Content type: Study protocol Published on:

  45. The utilization of total hip replacement (THR) surgery is rapidly increasing, however few data examine whether these procedures are associated with socioeconomic status (SES) within Australia. This study exami...

    Authors: Sharon L Brennan, Tyman Stanford, Anita E Wluka, Margaret J Henry, Richard S Page, Stephen E Graves, Mark A Kotowicz, Geoffrey C Nicholson and Julie A Pasco
    Citation: BMC Musculoskeletal Disorders 2012 13:63
    Content type: Research article Published on:

  46. Shoulder pain is the third most common reason for consultation with a physiotherapist and up to 26% of the general population might be expected to experience an episode at any one time. Disorders of the should...

    Authors: Chris Littlewood, Jon Ashton, Sue Mawson, Stephen May and Stephen Walters
    Citation: BMC Musculoskeletal Disorders 2012 13:62
    Content type: Study protocol Published on:

  47. Dupuytren’s contracture (DC) is a progressive fibroproliferative disorder characterized by development of nodules and collagen cords within the palmar fascia of the hand. Collagenase clostridium histolyticum (...

    Authors: Stephen Coleman, David Gilpin, James Tursi, Greg Kaufman, Nigel Jones and Brian Cohen
    Citation: BMC Musculoskeletal Disorders 2012 13:61
    Content type: Research article Published on:

  48. Osteoarthritis (OA) of the hip and knee are among the most common chronic conditions, resulting in substantial pain and functional limitations. Adequate management of OA requires a combination of medical and b...

    Authors: Kelli D Allen, Hayden B Bosworth, Dorothea S Brock, Jennifer G Chapman, Ranee Chatterjee, Cynthia J Coffman, Santanu K Datta, Rowena J Dolor, Amy S Jeffreys, Karen A Juntilla, Jennifer Kruszewski, Laurie E Marbrey, Jennifer McDuffie, Eugene Z Oddone, Nina Sperber, Mary P Sochacki…
    Citation: BMC Musculoskeletal Disorders 2012 13:60
    Content type: Study protocol Published on:

  49. Developmental dysplasia of the hip (DDH) is a congenital or acquired deformation or misalignment of the hip joint which affects mainly females. We hypothesized that HOXD9 gene could be regulated in acetabular siz...

    Authors: Wei Tian, Lixi Zhao, Jing Wang, Peisu Suo, Jianmin Wang, Longfei Cheng, Zhi Cheng, Jian Jia, Shilian Kan, Binbin Wang and Xu Ma
    Citation: BMC Musculoskeletal Disorders 2012 13:59
    Content type: Research article Published on:

  50. Pain Exposure Physical Therapy is a new treatment option for patients with Complex Regional Pain Syndrome type 1. It has been evaluated in retrospective as well as in prospective studies and proven to be safe ...

    Authors: Karlijn J Barnhoorn, Rob A B Oostendorp, Robert T M van Dongen, Frank P Klomp, Han Samwel, Gert Jan van der Wilt, Eddy Adang, Hans Groenewoud, Henk van de Meent and Jan Paul M Frölke
    Citation: BMC Musculoskeletal Disorders 2012 13:58
    Content type: Study protocol Published on:
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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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