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  1. The objective of this study was to investigate the protective effects of molecular hydrogen, a novel and selective antioxidant, on steroid-induced osteonecrosis (ON) in a rabbit model.

    Authors: Jia Li, Zhaogang Ge, Lihong Fan and Kunzheng Wang
    Citation: BMC Musculoskeletal Disorders 2017 18:58
  2. Heterogeneity in patients with low back pain (LBP) is well recognised and different approaches to subgrouping have been proposed. Latent Class Analysis (LCA) is a statistical technique that is increasingly bei...

    Authors: Anne Molgaard Nielsen, Peter Kent, Lise Hestbaek, Werner Vach and Alice Kongsted
    Citation: BMC Musculoskeletal Disorders 2017 18:57
  3. Low back pain is common and associated with a considerable burden to patients and society. There is uncertainty regarding the relative benefit of paracetamol and diclofenac and regarding the additional effect ...

    Authors: M. Schreijenberg, P. A. J. Luijsterburg, Y. D. M. Van Trier, D. Rizopoulos, M. A. Koopmanschap, L. Voogt, C. G. Maher and B. W. Koes
    Citation: BMC Musculoskeletal Disorders 2017 18:56
  4. Hip joint complaints are a problem associated with increasing age and impair the mobility of a large section of the elderly population. Reliable and valid tests are necessary for a thorough investigation of a ...

    Authors: Rahel Lenzlinger-Asprion, Niculina Keller, André Meichtry and Hannu Luomajoki
    Citation: BMC Musculoskeletal Disorders 2017 18:55
  5. Scapholunate dissociation is the most common form of carpal instability. However, there is no gold standard for operative treatment. In this prospective observational study on 54 patients, a modified minimally...

    Authors: Alexander Kaltenborn, Sebastian Hoffmann, Andreas Settje, Peter M. Vogt, André Gutcke and Mike Rüttermann
    Citation: BMC Musculoskeletal Disorders 2017 18:54
  6. Systemic Lupus erythematosus (SLE), also commonly referred to as lupus, is a rare, but sometimes, fatal disease, that primarily affects young women. Lupus nephritis, a common manifestation of lupus, is more co...

    Authors: Jasvinder A. Singh, Nipam Shah and Candace Green
    Citation: BMC Musculoskeletal Disorders 2017 18:53
  7. Due to the risk associated with exposure to ionizing radiation, there is an urgent need to identify areas of CT scanning overutilization. While increased use of diagnostic spinal imaging has been documented, n...

    Authors: Vikas V. Patel, Gunnar B. J. Andersson, Steven R. Garfin, Donald L. Resnick and Jon E. Block
    Citation: BMC Musculoskeletal Disorders 2017 18:52
  8. Spinal deformities affect the overall alignment of the spine and thus the vectors of loading on the lumbar region and intervertebral discs. Due to wedging of the disc or vertebrae of unbalanced spinal segments...

    Authors: Kamil Eyvazov, Dino Samartzis and Jason Pui Yin Cheung
    Citation: BMC Musculoskeletal Disorders 2017 18:51
  9. Acetabular dysplasia (AD) is a well-known cause of osteoarthritis (OA) of the hip, with its prevalence previously determined on plain radiography. The prevalence of preexisting AD was reported as 7.3% in a pat...

    Authors: Tomohiro Mimura, Kanji Mori, Masahiro Kitagawa, Mariko Ueki, Yuki Furuya, Taku Kawasaki and Shinji Imai
    Citation: BMC Musculoskeletal Disorders 2017 18:50
  10. The purpose of this prospective cohort study was to clarify the safety and efficacy of total hip arthroplasty via the direct anterior approach in the supine position with a novel mobile traction table.

    Authors: Junichi Nakamura, Shigeo Hagiwara, Sumihisa Orita, Ryuichiro Akagi, Takane Suzuki, Masahiko Suzuki, Kazuhisa Takahashi and Seiji Ohtori
    Citation: BMC Musculoskeletal Disorders 2017 18:49
  11. Research has suggested that patient expectations are associated with treatment outcome and evolve along with patient communication within the musculoskeletal field. However, few studies have investigated if or...

    Authors: Sigrid Skatteboe, Cecilie Røe, Morten Wang Fagerland and Lars-Petter Granan
    Citation: BMC Musculoskeletal Disorders 2017 18:48
  12. Some cadaveric studies have reported the role of the distal oblique bundle (DOB) in the distal radioulnar joint stability. We aimed to determine whether the presence of the DOB can be identified and its thickn...

    Authors: Yeon Ho Kim, Hyun Sik Gong, Jin Woo Park, Hyun Kyung Yang, Kahyun Kim and Goo Hyun Baek
    Citation: BMC Musculoskeletal Disorders 2017 18:47
  13. Osteoporosis and osteoporotic fractures remain significant public health challenges worldwide. Recently the concept of frailty in relation to osteoporosis in the elderly has been increasingly accepted, with em...

    Authors: Guowei Li, Lehana Thabane, Alexandra Papaioannou, George Ioannidis, Mitchell A. H. Levine and Jonathan D. Adachi
    Citation: BMC Musculoskeletal Disorders 2017 18:46
  14. There are no core outcome domain or measurement sets for Total Joint Replacement (TJR) clinical trials. Our objective was to achieve an International consensus by orthopaedic surgeons on the OMERACT core domai...

    Authors: Jasvinder A. Singh, Michael Dohm and Peter F. Choong
    Citation: BMC Musculoskeletal Disorders 2017 18:45
  15. Intra-articular corticosteroid injections (IACI) are effective treatments for pain in knee osteoarthritis (KOA) but treatment response varies. There is uncertainty as to whether structural factors such as accu...

    Authors: G. Hirsch, T. W. O’Neill, G. Kitas, A. Sinha and R. Klocke
    Citation: BMC Musculoskeletal Disorders 2017 18:44
  16. The Internet is increasingly used to access health information, although the quality of information varies. The aim of this study was to evaluate the readability, and quality of websites about polymyalgia rheu...

    Authors: Arani Vivekanantham, Joanne Protheroe, Sara Muller and Samantha Hider
    Citation: BMC Musculoskeletal Disorders 2017 18:43
  17. Osteoarthritis is one of the leading causes of inactivity worldwide. The recommended level of health enhancing physical activity (HEPA) is at least 150 min of moderate intensity physical activity per week. The...

    Authors: Anna Ernstgård, MirNabi PirouziFard and Carina A. Thorstensson
    Citation: BMC Musculoskeletal Disorders 2017 18:42
  18. Physical examination tests of the shoulder (PETS) are clinical examination maneuvers designed to aid the assessment of shoulder complaints. Despite more than 180 PETS described in the literature, evidence of t...

    Authors: Sigmund Ø. Gismervik, Jon O. Drogset, Fredrik Granviken, Magne Rø and Gunnar Leivseth
    Citation: BMC Musculoskeletal Disorders 2017 18:41
  19. The purpose of this study was to determine whether additional tension band wiring in the plate for traumatic disruption of symphysis pubis has clinical benefits. Therefore, outcomes and complications were comp...

    Authors: Myung-sik Park, Sun-Jung Yoon, Seung-min Choi and Kwanghun Lee
    Citation: BMC Musculoskeletal Disorders 2017 18:40
  20. Inflammation is a major cause of cartilage destruction and leads to the imbalance of metabolic activities in the arthritic joint. Pigment epithelium-derived factor (PEDF) has been reported to have both pro- an...

    Authors: Daisy S. Nakamura, Judith M. Hollander, Tomoya Uchimura, Heber C. Nielsen and Li Zeng
    Citation: BMC Musculoskeletal Disorders 2017 18:39
  21. Conversion to total hip arthroplasty (CTHA) is a relatively common procedure after a failed dynamic hip screw (DHS) or proximal femoral nail anti-rotation (PFNA) fixation of intertrochanteric fractures, but th...

    Authors: Xianshang Zeng, Ke Zhan, Lili Zhang, Dan Zeng, Weiguang Yu, Xinchao Zhang and Mingdong Zhao
    Citation: BMC Musculoskeletal Disorders 2017 18:38
  22. Increased Serum insulin-like growth factor-1 (S-IGF-1) has been noted after physical activity in healthy subjects, while the acute release of S-IGF-1 in relation to exercise has not previously been studied in ...

    Authors: Kaisa Mannerkorpi, Kerstin Landin-Wilhelmsen, Anette Larsson, Ã…sa Cider, Olivia Arodell and Jan L. Bjersing
    Citation: BMC Musculoskeletal Disorders 2017 18:37
  23. It is still debated whether strenuous running in the inflammatory phase produces beneficial or harmful effect in rat knees. We examined (1) the dropout rate of rats during a 30-km running protocol, (2) influen...

    Authors: Ryusuke Saito, Takeshi Muneta, Nobutake Ozeki, Yusuke Nakagawa, Mio Udo, Katsuaki Yanagisawa, Kunikazu Tsuji, Makoto Tomita, Hideyuki Koga and Ichiro Sekiya
    Citation: BMC Musculoskeletal Disorders 2017 18:36
  24. Osteoid osteoma (OO) is a common benign bone tumour that is rarely found in the talus. Its nidus is difficult to detect on early imaging. The atypical symptoms of OO and the presence of concurrent trauma or sp...

    Authors: Huan He, Hailin Xu, Hao Lu, Yu Dang, Wei Huang and Qing Zhang
    Citation: BMC Musculoskeletal Disorders 2017 18:35
  25. Modic 1 changes are usually associated with degenerative disc disease (DDD). We aimed to compare Modic 1 changes with advanced degenerative disc disease (>50%-intervertebral space narrowing [IVSN]) to Modic 1 ...

    Authors: Christelle Nguyen, Marylène Jousse, Serge Poiraudeau, Antoine Feydy and François Rannou
    Citation: BMC Musculoskeletal Disorders 2017 18:34
  26. Chronic hematogenous osteomyelitis often results from the improper treatment of acute hematogenous osteomyelitis. At present, there is lack of uniform standards for the treatment, and the clinical features of ...

    Authors: Xiaohua Wang, Zhen Wang, Jingshu Fu, Ke Huang and Zhao Xie
    Citation: BMC Musculoskeletal Disorders 2017 18:33
  27. Angiomatoid fibrous histiocytoma (AFH) is a rare soft tissue tumor of intermediate biologic potential. Because of its rarity and nonspecific radiological and diverse pathological findings, AFH is often clinica...

    Authors: Kenichi Saito, Eisuke Kobayashi, Akihiko Yoshida, Yoshihiro Araki, Daisuke Kubota, Yoshikazu Tanzawa, Akira Kawai, Takashi Yanagawa, Kenji Takagishi and Hirokazu Chuman
    Citation: BMC Musculoskeletal Disorders 2017 18:31
  28. Unstable Neer Type IIB fractures require meticulous surgical treatment. Thus, the aim of this study was to present long-term outcomes after plate fixation and minimally invasive coracoclavicular (CC) stabiliza...

    Authors: Thomas M. Tiefenboeck, Sandra Boesmueller, Harald Binder, Adam Bukaty, Michael M. Tiefenboeck, Julian Joestl, Marcus Hofbauer and Roman C. Ostermann
    Citation: BMC Musculoskeletal Disorders 2017 18:30
  29. Atypical femoral fractures (AFFs) are rare events associated with increased duration of bisphosphonate exposure. Recommended management of AFFs include cessation of bisphosphonates and imaging of the contralat...

    Authors: Neil Eisenstein, Ganesh Kasavkar, Dhruva Bhavsar, Faisal Shehzaad Khan and Zoe Paskins
    Citation: BMC Musculoskeletal Disorders 2017 18:29
  30. Few longitudinal studies have described the variation in LBP and its impact over time at an individual level. The aims of this study were to: 1) determine the prevalence of LBP in three surveys over a 9-year p...

    Authors: Per Kjaer, Lars Korsholm, Charlotte Leboeuf-Yde, Lise Hestbaek and Tom Bendix
    Citation: BMC Musculoskeletal Disorders 2017 18:28
  31. Heterotopic ossification (HO) is a well-known complication after total hip arthroplasty (THA).

    Authors: Maya Hürlimann, Filippo-Franco Schiapparelli, Niccolo Rotigliano, Enrique Testa, Felix Amsler and Michael T. Hirschmann
    Citation: BMC Musculoskeletal Disorders 2017 18:27
  32. Locking compress plate, as external fixator, is an attractive technique for distal tibial fracture treatment. But it still remains unclear whether the external LCP has sufficient stiffness. Thus, the present s...

    Authors: Wei Liu, Lihui Yang, Xiaochuan Kong, Likun An, Gang Hong, Zicheng Guo and Lei Zang
    Citation: BMC Musculoskeletal Disorders 2017 18:26
  33. There is increasing interest in paravertebral muscle composition as a potential prognostic and diagnostic element in lumbar spine health. As a consequence, it is becoming popular to use magnetic resonance imag...

    Authors: Rebecca J. Crawford, Jon Cornwall, Rebecca Abbott and James M. Elliott
    Citation: BMC Musculoskeletal Disorders 2017 18:25
  34. Collapse of the femoral head associated with nontraumatic osteonecrosis (NOFH) is one of the most common causes of disability in young adult patients. Excessive bone resorption by osteoclast coincident with th...

    Authors: Ryuta Arai, Daisuke Takahashi, Masahiro Inoue, Tohru Irie, Tsuyoshi Asano, Takuya Konno, Mohamad Alaa Terkawi, Tomohiro Onodera, Eiji Kondo and Norimasa Iwasaki
    Citation: BMC Musculoskeletal Disorders 2017 18:24
  35. Osteochondral lesions of the talus (OLTs) are amongst the most common foot and ankle disorders. Varus ankle malalignment causes stress concentration on medial side of the joint, resulting in OLTs and osteoarth...

    Authors: Xingchen Li, Yuan Zhu, Yang Xu, Bibo Wang, Jinhao Liu and Xiangyang Xu
    Citation: BMC Musculoskeletal Disorders 2017 18:23
  36. Fibromyalgia is a disease with an increasing incidence. It impairs the quality of life of patients and decreases their functional capacity. Aquatic therapy has already been used for managing the symptoms of th...

    Authors: Sabela Rivas Neira, Amélia Pasqual Marques, Irene Pegito Pérez, Ramón Fernández Cervantes and Jamile Vivas Costa
    Citation: BMC Musculoskeletal Disorders 2017 18:22
  37. Interstitial lung disease (ILD) is frequently associated with rheumatoid arthritis (RA), and is designated RA-associated ILD (RA-ILD). RA-ILD has a large impact on the prognosis of RA. Here, we investigated th...

    Authors: Shomi Oka, Hiroshi Furukawa, Kota Shimada, Atsushi Hashimoto, Akiko Komiya, Naoshi Fukui, Naoyuki Tsuchiya and Shigeto Tohma
    Citation: BMC Musculoskeletal Disorders 2017 18:21
  38. Inhibition of activin/myostatin pathway has emerged as a novel approach to increase muscle mass and bone strength. Duchenne muscular dystrophy (DMD) is a neuromuscular disorder that leads to progressive muscle...

    Authors: Tero Puolakkainen, Hongqian Ma, Heikki Kainulainen, Arja Pasternack, Timo Rantalainen, Olli Ritvos, Kristiina Heikinheimo, Juha J. Hulmi and Riku Kiviranta
    Citation: BMC Musculoskeletal Disorders 2017 18:20
  39. Low back pain (LBP) is a major cause of disability throughout the world. However, longitudinal evidence to relate low back pain and functional limitations is mostly confined to Western countries. In this study...

    Authors: Vasoontara Yiengprugsawan, Damian Hoy, Rachelle Buchbinder, Chris Bain, Sam-ang Seubsman and Adrian C. Sleigh
    Citation: BMC Musculoskeletal Disorders 2017 18:19
  40. Low back pain is a common and costly condition internationally. There is high need to identify effective and economically efficient means for managing this problem. This study aimed to explore the cost-effecti...

    Authors: Terry Haines and Kelly-Ann Bowles
    Citation: BMC Musculoskeletal Disorders 2017 18:18
  41. There are few studies with an assessment of the levels of cytokines or neuropeptides as correlates of pain and pain relief in patients with painful joint diseases. Our objective was to assess whether improveme...

    Authors: Jasvinder A. Singh, Siamak Noorbaloochi and Keith L. Knutson
    Citation: BMC Musculoskeletal Disorders 2017 18:17
  42. Preoperative planning with the aid of imaging methods is a principal factor in successful surgery on the shoulder. This work aims to evaluate the variability of glenoid version, spiralling twist and scapular i...

    Authors: Petr Fulin, Martin Kysilko, David Pokorny, Radek Padr, Nikola Kasprikova, Ivan Landor and Antonin Sosna
    Citation: BMC Musculoskeletal Disorders 2017 18:16
  43. Rates of chronic pain are rising sharply in the United States and worldwide. Presently, there is evidence of racial disparities in pain treatment and treatment outcomes in the United States but few interventio...

    Authors: Rozina H. Bhimani, Lee J. S. Cross, Brent C. Taylor, Laura A. Meis, Steven S. Fu, Kelli D. Allen, Sarah L. Krein, Tam Do, Robert D. Kerns and Diana J. Burgess
    Citation: BMC Musculoskeletal Disorders 2017 18:15
  44. Outcomes after total knee (TKA) and hip (THA) arthroplasty are often generalized internationally. Patient-dependent factors and preoperative symptom levels may differ across countries. We compared preoperative...

    Authors: Patricia D. Franklin, Hermes Miozzari, Panayiotis Christofilopoulos, Pierre Hoffmeyer, David C. Ayers and Anne Lübbeke
    Citation: BMC Musculoskeletal Disorders 2017 18:14
  45. Within work sociology, several studies have addressed construction workers’ practices of masculinity, class, economy, safety risks and production. However, few studies have investigated room for agency in rela...

    Authors: Jeppe Zielinski Nguyen Ajslev, Roger Persson and Lars Louis Andersen
    Citation: BMC Musculoskeletal Disorders 2017 18:13
  46. Lumbar multifidus muscles (LMM) are important for spinal motion and stability. Low back pain (LBP) is often associated with fat infiltration in LMM. An increasing fat infiltration of LMM may lead to lumbar dys...

    Authors: Markus Hildebrandt, Gabriela Fankhauser, André Meichtry and Hannu Luomajoki
    Citation: BMC Musculoskeletal Disorders 2017 18:12
  47. Destructive spondyloarthropathy (DSA) is one of the major complications in patients undergoing long-term hemodialysis. To the best of our knowledge, an epidural abscess occurring at the level of preexisting ce...

    Authors: Jun-Seok Lee, Ji-Hyun Ryu, Jong-Tae Park and Ki-Won Kim
    Citation: BMC Musculoskeletal Disorders 2017 18:11
  48. Chronic diseases and multimorbidity are increasingly common among persons in working age. This study explores the impact of type, number and combinations of chronic diseases with focus on the role of MSKD on (...

    Authors: Antje van der Zee-Neuen, Polina Putrik, Sofia Ramiro, Andras Keszei, Rob de Bie, Astrid Chorus and Annelies Boonen
    Citation: BMC Musculoskeletal Disorders 2017 18:10
  49. Placement of the glenoid baseplate is of paramount importance for the outcome of anatomical and reverse total shoulder arthroplasty. However, the database around glenoid size is poor, particularly regarding sm...

    Authors: Sandra Mathews, Marco Burkhard, Nabil Serrano, Karl Link, Martin Häusler, Nakita Frater, Ingeborg Franke, Helena Bischofberger, Florian M. Buck, Dominic Gascho, Michael Thali, Steffen Serowy, Magdalena Müller-Gerbl, Gareth Harper, Ford Qureshi, Thomas Böni…
    Citation: BMC Musculoskeletal Disorders 2017 18:9

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