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Table 2 Comparison between the cervical and non-cervical lesion groups (univariate analysis)

From: Risk factors associated with cervical spine lesions in patients with rheumatoid arthritis: an observational study

  Cervical lesion group
(n = 106)
Non-cervical lesion group
(n = 79)
P-value*
Sex (n) (male:female) 6:100 6:73 0.60
Age (years) (IQR) 68 (62−73) 68 (62−75) 0.66
Age of onset (years) 48 (39−59) 59 (50−68) < 0.01
RA disease duration (years) (IQR) 15 (8−26) 6 (2−13) < 0.01
CRP level (mg/dL) (IQR) 0.4 (0.1−1.3) 0.2 (0.1−0.8) 0.06
RF positive (n) 62 % (66/106) 62 % (49/79) 0.97
MMP3 positive (n) 64 % (68/106) 67 % (53/79) 0.68
DAS28-CRP (IQR) 2.3 (1.9−3.0) 2.1 (1.6−3.1) 0.76
RA stage III or IV (n) 88 % (93/106) 46 % (36/79) < 0.01
Prednisolone (n) 58 % (61/106) 37 % (29/79) < 0.01
MTX (n) 60 % (64/106) 66 % (52/79) 0.45
Biological agents (n) 53 % (56/106) 19 % (15/79) < 0.01
BMD of the lumbar spine (YAM) (IQR) 79 (70−91) 86 (78−95) 0.09
BMD of the femoral neck (YAM) (IQR) 64 (57−72) 72 (64−81) < 0.01
Previous joint surgery (n) 41 % (43/106) 23 % (18/79) 0.01
  1. BMD bone mineral density, CRP C-reactive protein, DAS28-CRP Disease Activity Score based on C-reactive protein, MTX methotrexate, MMP3 matrix metalloproteinase-3, RF rheumatoid factor, YAM young adult mean, IQR interquartile range
  2. *The P-value was calculated using the chi-square test, Student t-test, or Mann−Whitney U test