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Table 2 Comparison between the cervical and non-cervical lesion groups (univariate analysis)

From: Risk factors associated with cervical spine lesions in patients with rheumatoid arthritis: an observational study

 

Cervical lesion group

(n = 106)

Non-cervical lesion group

(n = 79)

P-value*

Sex (n) (male:female)

6:100

6:73

0.60

Age (years) (IQR)

68 (62−73)

68 (62−75)

0.66

Age of onset (years)

48 (39−59)

59 (50−68)

< 0.01

RA disease duration (years) (IQR)

15 (8−26)

6 (2−13)

< 0.01

CRP level (mg/dL) (IQR)

0.4 (0.1−1.3)

0.2 (0.1−0.8)

0.06

RF positive (n)

62 % (66/106)

62 % (49/79)

0.97

MMP3 positive (n)

64 % (68/106)

67 % (53/79)

0.68

DAS28-CRP (IQR)

2.3 (1.9−3.0)

2.1 (1.6−3.1)

0.76

RA stage III or IV (n)

88 % (93/106)

46 % (36/79)

< 0.01

Prednisolone (n)

58 % (61/106)

37 % (29/79)

< 0.01

MTX (n)

60 % (64/106)

66 % (52/79)

0.45

Biological agents (n)

53 % (56/106)

19 % (15/79)

< 0.01

BMD of the lumbar spine (YAM) (IQR)

79 (70−91)

86 (78−95)

0.09

BMD of the femoral neck (YAM) (IQR)

64 (57−72)

72 (64−81)

< 0.01

Previous joint surgery (n)

41 % (43/106)

23 % (18/79)

0.01

  1. BMD bone mineral density, CRP C-reactive protein, DAS28-CRP Disease Activity Score based on C-reactive protein, MTX methotrexate, MMP3 matrix metalloproteinase-3, RF rheumatoid factor, YAM young adult mean, IQR interquartile range
  2. *The P-value was calculated using the chi-square test, Student t-test, or Mann−Whitney U test