Figure 5From: Connexin43 enhances the expression of osteoarthritis-associated genes in synovial fibroblasts in culture Modulation of Cx43 expression affected the NFκB pathway. Immunoblots from whole cell extracts of transiently transfected SW982 cells showed that (A) overexpression of Cx43 enhanced the abundance of phospho-p65 (RelA) subunit of the NFκB complex while (B) knockdown of Cx43 expression had the opposing effect. GAPDH was used as a load control.Back to article page