Motor activity alterations, Animex test. Motor capability was observed by measuring the number of movements in 5 minutes on a free surface. The test was performed 14 days after MIA injection and effect of daily repeated collagen administration starting from the day 1 was evaluated. Control animals were treated with vehicle. Each value represents the mean of 12 rats performed in 2 different experimental set. *P < 0.01 compared to vehicle + vehicle rats; §P < 0.05 and ^P < 0.01 compared to MIA + vehicle treated rats.