Study protocol: the effect of whole body vibration on acute unilateral unstable lateral ankle sprain- a biphasic randomized controlled trial

Table 1 Inclusion- and exclusion criteria

Inclusion criteria	Exclusion criteria
Age: 18 to 40 years	Pregnancy
Acute, unilateral, unstable, inversion ankle sprain (Grade II, III)	Conditions affecting the neuromuscular or musculoskeletal system
Signed informed consent	Previous surgical interventions to the foot, ankle, knee or hip; known FAI, CAI
Patient can read and understand German	Conditions possibly affecting balance
	Cardiovascular disease including thrombosis
	Respiratory diseases
	Abdominal diseases (including gallstones)
	Urological diseases (including kidney and bladder stones)
	Gynaecological diseases and + intrauterine devices
	Neurological diseases including epilepsy within the last 2 years
	Acute injuries to the head
	Patient is not available for follow-up visits
	Patient unable to give informed consent
	Patient suspected to be non-compliant

Functional classification system for lateral ankle sprains: Grade II: hematoma/swelling/pain on palpation and positive anterior drawer test (complete tear of the ATFL, incomplete tear of the CFL); Grade III: hematoma/swelling/pain on palpation and positive anterior drawer test and positive talar tilt test (complete tear of the ATFL and CFL); adapted from[46–48]; FAI: Functional ankle instability; CAI: Chronic ankle instability.

ISSN: 1471-2474