Todhunter PG, Kincaid SA, Todhunter RJ, Kammermann JR, Johnstone B, Baird AN, et al: Immunohistochemical analysis of an equine model of synovitis-induced arthritis. Am J Vet Res. 1996, 57: 1080-1093.
CAS
PubMed
Google Scholar
Guingamp C, Gegout-Pottie P, Philippe L, Terlain B, Netter P, Gillet P: Mono-iodoacetate-induced experimental osteoarthritis: a dose-response study of loss of mobility, morphology, and biochemistry. Arthritis Rheum. 1997, 40: 1670-1679. 10.1002/art.1780400917.
Article
CAS
PubMed
Google Scholar
Guzman RE, Evans MG, Bove S, Morenko B, Kilgore K: Monoiodoacetate-induced histologic changes in subchondral bone and articular cartilage of rat femorotibial joints: an animal model of osteoarthritis. Toxicol Pathol. 2003, 31: 619-624.
Article
CAS
PubMed
Google Scholar
Bove SE, Calcaterra SL, Brooker RM, Huber CM, Guzman RE, Juneau PL, et al: Weight bearing as a measure of disease progression and efficacy of anti-inflammatory compounds in a model of monosodium iodoacetate-induced osteoarthritis. Osteoarthritis Cartilage. 2003, 11: 821-830. 10.1016/S1063-4584(03)00163-8.
Article
CAS
PubMed
Google Scholar
Combe R, Bramwell S, Field MJ: The monosodium iodoacetate model of osteoarthritis: a model of chronic nociceptive pain in rats?. Neurosci Lett. 2004, 370: 236-240. 10.1016/j.neulet.2004.08.023.
Article
CAS
PubMed
Google Scholar
Bove SE, Laemont KD, Brooker RM, Osborn MN, Sanchez BM, Guzman RE, et al: Surgically induced osteoarthritis in the rat results in the development of both osteoarthritis-like joint pain and secondary hyperalgesia. Osteoarthritis Cartilage. 2006, 14: 1041-1048. 10.1016/j.joca.2006.05.001.
Article
CAS
PubMed
Google Scholar
Smith MD, Triantafillou S, Parker A, Youssef PP, Coleman M: Synovial membrane inflammation and cytokine production in patients with early osteoarthritis. J Rheumatol. 1997, 24: 365-371.
CAS
PubMed
Google Scholar
Fiorito S, Magrini L, Adrey J, Mailhe D, Brouty-Boye D: Inflammatory status and cartilage regenerative potential of synovial fibroblasts from patients with osteoarthritis and chondropathy. Rheumatology (Oxford). 2005, 44: 164-171.
Article
CAS
Google Scholar
Pearle AD, Scanzello CR, George S, Mandl LA, Dicarlo EF, Peterson M, et al: Elevated high-sensitivity C-reactive protein levels are associated with local inflammatory findings in patients with osteoarthritis. Osteoarthritis Cartilage. 2007, 15: 516-523. 10.1016/j.joca.2006.10.010.
Article
CAS
PubMed
Google Scholar
Ohtori S, Takahashi K, Moriya H, Myers RR: TNF-α and TNF-α receptor type 1 upregulation in glia and neurons after peripheral nerve injury: studies in murine DRG and spinal cord. Spine. 2004, 29: 1082-1088. 10.1097/00007632-200405150-00006.
Article
PubMed
Google Scholar
Pollock J, McFarlane SM, Connell MC, Zehavi U, Vandenabeele P, MacEwan DJ, et al: TNF-alpha receptors simultaneously activate Ca2+ mobilisation and stress kinases in cultured sensory neurons. Neuropharmacol. 2002, 42: 93-106. 10.1016/S0028-3908(01)00163-0.
Article
CAS
Google Scholar
Lotz M, Guerne PA: Interleukin-6 induces the synthesis of tissue inhibitor of metalloproteinases-1/erythroid potentiating activity (TIMP-1/EPA). J Biol Chem. 1991, 266: 2017-2020.
CAS
PubMed
Google Scholar
Iannone F, De Bari C, Dell'Accio F, Covelli M, Patella V, Lo Bianco G, Lapadula G: Increased expression of nerve growth factor (NGF) and high affinity NGF receptor (p140 TrkA) in human osteoarthritic chondrocytes. Rheumatology (Oxford). 2002, 41: 1413-1418. 10.1093/rheumatology/41.12.1413.
Article
CAS
Google Scholar
Manni L, Lundeberg T, Fiorito S, Bonini S, Vigneti E, Aloe L: Nerve growth factor release by human synovial fibroblasts prior to and following exposure to tumor necrosis factor-alpha, interleukin-1 beta and cholecystokinin-8: the possible role of NGF in the inflammatory response. Clin Exp Rheumatol. 2003, 21: 617-624.
CAS
PubMed
Google Scholar
Perry MJ, Lawson SN, Robertson J: Neurofilament immunoreactivity in populations of rat primary afferent neurons: a quantitative study of phosphorylated and non-phosphorylated subunits. J Neurocytol. 1991, 20: 746-758. 10.1007/BF01187848.
Article
CAS
PubMed
Google Scholar
Averill S, McMahon SB, Clary DO, et al: Immunocytochemical localization of trkA receptors in chemically identified subgroups of adult rat sensory neurons. Eur J Neurosci. 1995, 7: 1484-1494. 10.1111/j.1460-9568.1995.tb01143.x.
Article
CAS
PubMed
PubMed Central
Google Scholar
Molliver DC, Radeke MJ, Feinstein SC, et al: Presence or absence of TrkA protein distinguishes subsets of small sensory neurons with unique cytochemical characteristics and dorsal horn projections. J Comp Neurol. 1995, 361: 404-416. 10.1002/cne.903610305.
Article
CAS
PubMed
Google Scholar
Snider WD, McMahon SB: Tackling pain at the source: new ideas about nociceptors. Neuron. 1998, 20: 629-632. 10.1016/S0896-6273(00)81003-X.
Article
CAS
PubMed
Google Scholar
Sun R, Tu Y, Lawand N, et al: Calcitonin gene-related peptide receptor activation produces PKA- and PKC-dependent mechanical hyperalgesia and central sensitization. J Neurophysiol. 2004, 92: 2859-2866. 10.1152/jn.00339.2004.
Article
CAS
PubMed
Google Scholar
Buma P, Verschuren C, Versleyen D, Van der Kraan P, Oestreicher AB: Calcitonin gene-related peptide, substance P and GAP43/B-50 immunoreactivity in the normal and arthritic knee joint of the mouse. Histochemistry. 1992, 98: 327-339. 10.1007/BF00270017.
Article
CAS
PubMed
Google Scholar
Fernihough J, Gentry C, Bevan S, Winter J: Regulation of calcitonin gene-related peptide and TRPV1 in a rat model of osteoarthritis. Neurosci Lett. 2005, 388: 75-80. 10.1016/j.neulet.2005.06.044.
Article
CAS
PubMed
Google Scholar
Ivanavicius SP, Ball AD, Heapy CG, Westwood FR, Murray F, Read SJ: Structural pathology in a rodent model of osteoarthritis is associated with neuropathic pain: increased expression of ATF3 and pharmacological characterisation. Pain. 2007, 128: 272-282. 10.1016/j.pain.2006.12.022.
Article
CAS
PubMed
Google Scholar
Tsujino H, Kondo E, Fukuoka T, Dai Y, Tokunaga A, Miki K, et al: Activating transcription factor 3 (ATF3) induction by axotomy in sensory and motoneurons: a novel neuronal marker of nerve injury. Mol Cell Neurosci. 2000, 15: 170-182. 10.1006/mcne.1999.0814.
Article
CAS
PubMed
Google Scholar
Watkins LR, Milligan ED, Maier SF: Glial activation: a driving force for pathological pain. Trends Neurosci. 2001, 24: 450-455. 10.1016/S0166-2236(00)01854-3.
Article
CAS
PubMed
Google Scholar
DeLeo JA, Yezierski RP: The role of neuroinflammation and neuroimmune activation in persistent pain. Pain. 2001, 90: 1-6. 10.1016/S0304-3959(00)00490-5.
Article
CAS
PubMed
Google Scholar
Tsuda M, Inoue K, Salter MW: Neuropathic pain and spinal microglia: a big problem from molecules in "small" glia. Trends Neurosci. 2005, 28: 101-107. 10.1016/j.tins.2004.12.002.
Article
CAS
PubMed
Google Scholar
Nakamura S, Myers RR: Injury to dorsal root ganglia alters innervation of spinal cord dorsal horn lamina involved in nociception. Spine. 2000, 25: 537-542. 10.1097/00007632-200003010-00002.
Article
CAS
PubMed
Google Scholar
Fernihough J, Gentry C, Malcangio M, Fox A, Rediske J, Pellas T, et al: Pain related behaviour in two models of osteoarthritis in the rat knee. Pain. 2004, 112: 83-93. 10.1016/j.pain.2004.08.004.
Article
PubMed
Google Scholar
Nakajima T, Ohtori S, Yamamoto S, Takahashi K, Harada Y: Differences in innervation and innervated neurons between hip and inguinal skin. Clin Orthop Relat Res. 2008, 466: 2527-2532. 10.1007/s11999-008-0432-z.
Article
PubMed
PubMed Central
Google Scholar
Janusz MJ, Bendele AM, Brown KK, Taiwo YO, Hsieh L, Heitmeyer SA: Induction of osteoarthritis in the rat by surgical tear of the meniscus: inhibition of joint damage by a matrix metalloproteinase inhibitor. Osteoarthritis Cartilage. 2002, 10: 785-791. 10.1053/joca.2002.0823.
Article
CAS
PubMed
Google Scholar
Schaible HG: Neurophysiology of nociception and pain reactions in inflammatory joint diseases. Rev Rhum Engl Ed. 1997, 64: 144S-145S.
CAS
PubMed
Google Scholar
Aloisi AM, Porro CA, Cavazzuti M, Baraldi P, Carli G: 'Mirror pain' in the formalin test: behavioral and 2-deoxyglucose studies. Pain. 1993, 55: 267-273. 10.1016/0304-3959(93)90156-J.
Article
CAS
PubMed
Google Scholar
Goldring MB, Goldring SR: Osteoarthritis. J Cell Physiol. 2007, 213: 626-634. 10.1002/jcp.21258.
Article
CAS
PubMed
Google Scholar
Loeser RF: Molecular mechanisms of cartilage destruction: mechanics, inflammatory mediators, and aging collide. Arthritis Rheum. 2006, 54: 1357-1360. 10.1002/art.21813.
Article
CAS
PubMed
PubMed Central
Google Scholar
Lee KM, Jeon SM, Cho HJ: Tumor necrosis factor receptor 1 induces interleukin-6 upregulation through NF-kappaB in a rat neuropathic pain model. Eur J Pain. 2009, 13: 794-806. 10.1016/j.ejpain.2008.09.009.
Article
CAS
PubMed
Google Scholar
Van Bladel S, Libert C, Fiers W: Interleukin-6 enhances the expression of tumor necrosis factor receptors on hepatoma cells and hepatocytes. Cytokine. 1991, 3: 149-154. 10.1016/1043-4666(91)90036-D.
Article
CAS
PubMed
Google Scholar
Pezet S, McMahon SB: Neurotrophins: mediators and modulators of pain. Annu Rev Neurosci. 2006, 29: 507-538. 10.1146/annurev.neuro.29.051605.112929.
Article
CAS
PubMed
Google Scholar
Woolf CJ, Safieh-Garabedian B, Ma QP, Crilly P, Winter J: Nerve growth factor contributes to the generation of inflammatory sensory hypersensitivity. Neuroscience. 1994, 62: 327-331. 10.1016/0306-4522(94)90366-2.
Article
CAS
PubMed
Google Scholar
Mantyh PW, Rogers SD, Honore P, Allen BJ, Ghilardi JR, Li J, et al: Inhibition of hyperalgesia by ablation of lamina I spinal neurons expressing the substance P receptor. Science. 1997, 278: 275-279. 10.1126/science.278.5336.275.
Article
CAS
PubMed
Google Scholar
Koltzenburg M, Bennett DLH, Shelton DL, McMahon SB: Neutralization of endogenous NGF prevents the sensitization of nociceptors supplying inflamed skin. Eur J Neurosci. 1999, 11: 1698-1704. 10.1046/j.1460-9568.1999.00590.x.
Article
CAS
PubMed
Google Scholar
Ivanavicius SP, Blake DR, Chessell IP, Mapp PI: Isolectin B4 binding neurons are not present in the rat knee joint. Neuroscience. 2004, 128: 555-560. 10.1016/j.neuroscience.2004.06.047.
Article
CAS
PubMed
Google Scholar
Averill S, Michael GJ, Shortland PJ, Leavesley RC, King VR, Bradbury EJ, et al: NGF and GDNF ameliorate the increase in ATF3 expression which occurs in dorsal root ganglion cells in response to peripheral nerve injury. Eur J Neurosci. 2004, 19: 1437-1445. 10.1111/j.1460-9568.2004.03241.x.
Article
PubMed
Google Scholar
Ogino S, Sasho T, Nakagawa K, Suzuki M, Yamaguchi S, Higashi M, et al: Detection of pain-related molecules in the subchondral bone of osteoarthritic knees. Clin Rheumatol. 2009, 28: 1395-1402. 10.1007/s10067-009-1258-0.
Article
PubMed
Google Scholar
Tsujino H, Kondo E, Fukuoka T, Dai Y, Tokunaga A, Miki K, et al: Activating transcription factor 3 (ATF3) induction by axotomy in sensory and motoneurons: A novel neuronal marker of nerve injury. Mol Cell Neurosc. 2000, 15: 170-82. 10.1006/mcne.1999.0814.
Article
CAS
Google Scholar
Milligan ED, Twining C, Chacur M, Biedenkapp J, O'Connor K, Poole S, et al: Spinal glia and proinflammatory cytokines mediate mirror-image neuropathic pain in rats. J Neurosci. 2003, 23: 1026-1040.
CAS
PubMed
Google Scholar
Schafers M, Svensson CI, Sommer C, Sorkin LS: Tumor necrosis factor-alpha induces mechanical allodynia after spinal nerve ligation by activation of p38 MAPK in primary sensory neurons. J Neurosci. 2003, 23: 2517-2521.
CAS
PubMed
Google Scholar
Witoński D, Wagrowska-Danilewicz M, Raczyńska-Witońska G: Distribution of substance P nerve fibers in osteoarthritis knee joint. Pol J Pathol. 2005, 56: 203-6.
PubMed
Google Scholar
Ferreira-Gomes J, Adães S, Castro-Lopes JM: Assessment of movement-evoked pain in osteoarthritis by the knee-bend and CatWalk tests: a clinically relevant study. J Pain. 2008, 9: 945-954. 10.1016/j.jpain.2008.05.012.
Article
PubMed
Google Scholar
Sekiguchi M, Shirasaka M, Konno S, Kikuchi S: Analgesic effect of percutaneously absorbed non-steroidal anti-inflammatory drugs: an experimental study in a rat acute inflammation model. BMC Musculoskelet Disord. 2008, 9: 15-10.1186/1471-2474-9-15.
Article
PubMed
PubMed Central
Google Scholar