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Table 1 Design characteristics of included studies

From: Anterior knee pain in younger adults as a precursor to subsequent patellofemoral osteoarthritis: a systematic review

Author, year of publication

Design

Setting

Sampling procedure

AKP method of ascertainment, definition

PFOA method of ascertainment, definition

Length of follow-up

Utting et al 2005 [18]

Retrospective unmatched case-control.

Hospital orthopaedic surgery (Bristol, UK).

Local arthroplasty database (?period).

Cases

Isolated PF arthroplasty for severe isolated PFOA.

Controls

medial TF unicompartmental arthroplasty.

Self-complete questionnaire.

Recall of AKP as a child, teenager, or young adult.

Severe isolated PFOA requiring patellofemoral arthroplasty.

-

Kannus et al 1999 [19]

Prospective follow-up of RCT.

Hospital orthopaedic outpatients (Tampere, Finland).

Consecutive patients with unilateral PFPS enrolled in RCT of conservative therapy (1987-1990).

Clinical interview, examination and plain x-ray.

Retropatellar pain and crepitus with no other knee abnormalities.

Plain x-rays (AP, lateral, tunnel, tangential) and MRI.

PFOA classified as none, mild, moderate, or severe for each imaging modality.

Mean 6.6 years.

Nimon et al 1998 [20]

Prospective follow-up of case series.

Hospital orthopaedic outpatients (Oxford, UK).

Consecutive adolescent female patients with idiopathic AKP (1974-1980).

Clinical history, examination, plain x-ray.

No specific definition provided (other definitive diagnoses excluded, all complained of pain on ascending/descending stairs, squatting, or prolonged sitting).

Plain x-rays (AP, lateral, skyline).

No specific definition provided.

Mean 16 years (range 14-20).

Imhoff & Boni 1989 [21]

Prospective follow-up of two case series.

Orthopaedic outpatients, (Zurich, Switzerland).

?consecutive patients with PF pain undergoing conservative or surgical treatment (1953-1968).

Unclear.

No specific definition provided.

Plain x-rays (views not specified).

Films scored using a 4-point radiographic definition, based on that of Jäger & Wirth [25].

Mean 23 years.

Hvid et al 1981 [22]

Prospective follow-up of case series.

Hospital orthopaedics/diagnostic radiology

(Nykøbing, Denmark).

Patients with chondromalacia patellae on arthrography (1972-1977).

Clinical history, physical examination, and arthrogram.

No specific definition provided.

"a significant clinical syndrome" of chondromalacia patellae.

Plain x-rays (frontal, lateral, axial [26]).

No specific definition provided ("signs of arthrosis were searched for on all films")

Mean 5.7 years.

Dexel et al 1980 [23]

Prospective follow-up of two case series.

Orthopaedic outpatients, (Zurich, Switzerland).

?consecutive patients with PF pain undergoing conservative or surgical treatment (1953-1968).

Unclear.

No specific definition provided.

Plain x-rays (views not specified).

4-point radiographic definition, based on that of Tapper & Hoover [27].

Mean 13 years.

Karlson 1939 [24]

Prospective follow-up of comparative case series.

Hospital orthopaedics

(Stockholm, Sweden).

? consecutive male patients (mostly army conscripts) with "simple chondromalacia patellae" of both traumatic and non-traumatic origin

(1917-1934).

Clinical history and physical examination.

No specific definition provided.

Plain x-rays (views not specified).

No specific definition provided ("arthritis deformans").

Mean 5.9 years (range 1-20).

  1. AKP Anterior knee pain; AP Anteroposterior; PF Patellofemoral; PFOA Patellofemoral osteoarthritis; PFPS Patellofemoral pain syndrome; RCT Randomised controlled trial; TF Tibiofemoral