Figure 3

Effects on the bone mechanical properties of lumbar vertebra in OVX rats. Starting 12 weeks after OVX, drugs were administered orally to rats for 12 weeks. The ultimate load, the stiffness and the energy in the fifth vertebral body were determined, as described in MATERIALS AND METHODS. Each value represents the mean ± SE (n = 7–8). **p < 0.01, **p < 0.01 compared with the OVX-control group. Note that the combination therapy with ALF and RIS increased the ultimate load more effectively than RIS alone (p < 0.01).