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Section Editors' highlights

Welcome to the BMC Musculoskeletal Disorders Section Editors' highlights page. Here, the Section Editors have chosen recent papers published in their section of the journal that are of particular importance or interest to highlight to a wider audience. 

Clinical diagnostic and imaging - chosen by Daichi Hayashi
Clinical rheumatology and osteoporosis - chosen by Jeffrey Driban
Orthopedics and biomechanics - chosen by Giuseppe Longo
Pathophysiology of musculoskeletal disorders - chosen by Ali Mobasheri
Rehabilitation, physical therapy and occupational health - chosen by Bart Staal

5-alpha reductase inhibitors on osteoporosis and fracture risk

Dutasteride and finasteride are used in prostate cancer treatment, but a comparison of their effects on bone health have not been examined. A large Canadian cohort of men treated with either dutasteride or finasteride has been used the risk of osteoporosis or fractures examined. Despite differential effects, dutasteride was not associated with an increased risk relative to finasteride, suggesting that dutasteride does not adversely affect bone health.

Musculoskeletal disorders among preschool teachers

Work has many beneficial effects, but can also have a detrimental effect on health. In this study, the authors investigated the occurrence and impact of musculoskeletal disorders in female preschool teachers. They found that having an MSD had a negative effect on relational demands of the job, its meaning and subsequent intention to leave compared with MSD-free teachers.

Feasibility of 7T MRI in knee cartilage imaging

Delayed Gadolinium Enhanced Magnetic Resonance Image of Cartilage (dGEMRIC) is a well-established method for early assessment of cartilage quality in osteoarthritis. Here, the authors demonstrate in humans in vivo that T1 mapping for use in the dGEMRIC method is feasible at 7 T with similar normalized T1 values compared to at 1.5 T and that there is a strong correlation between T1 values at 1.5 T and 7 T. 

Effect of oral tranexamic acid in total knee athroplasty

In this RCT in the setting of total knee arthroplasty using a fast-track protocol, with no tourniquet and postoperative drain, the authors demonstrate that oral administration of TXA provided an equivalent blood-saving benefit compared with intra-articular TXA administration with great cost savings and no increased thromboembolic events

Inter-rater reliability of ultrasound in back pain

Ultrasound is increasingly being used as a diagnostic tool for musculoskeletal disorders. Here the inter-rater reliability of measuring morphological features in thoracolumbar fascia ultrasound images by a variety of medical practitioners was determined. The authors report good agreement and highlight the potential to use of these findings in the establishment of a clinical diagnostic scale for thoracolumbar fascia.

Long-term evaluation of outcomes and survivorship in a TKA cohort

In this paper, the authors presents the results of a prospective non-comparative study evaluating the long-term performance of a rotating platform TKA using predominantly cementless fixation and without patellar resurfacing. They found that this technique had an excellent survivorship at a minimum 10-year follow-up with the expectation that longer-term follow-up may be superior to cemented TKA.

Treating sleep disturbance in chronic pain

Most people suffering chronic pain are also plagued by sleeping difficulties. Here, Wilund et al. compared the effects of CBT or exercise on insomnia in patients with chronic pain. Unlike CBT, exercise caused a reduction in pain intensity, but both had little effect on insomnia, suggesting that non-specific treatments that do not target sleep itself are not enough to remedy sleeping problems in most patients with chronic pain conditions.

Cytokine profiling in hip osteoarthritis

Inflammation is associated with the onset and progression of osteoarthritis in multiple joints. Here, the authors show that, although cytokine profiles are generally similar between hip and knee OA, there are specific differences that may be related to differential disease processes within a given joint.