Articles

Intra-articular therapy with methotrexate or tumor necrosis factor inhibitors in rheumatoid arthritis: a systematic review

Persistent monoarthritis in otherwise well-controlled rheumatoid arthritis presents a therapeutic challenge. Intra-articular (IA) steroids are a mainstay of treatment, though some have queried whether IA disea...

Authors: Megan M. Sullivan, Michael M. Pham, Lisa A. Marks and Fawad Aslam

Evaluation of the standard procedure for treatment of periprosthetic joint infections of total knee and hip arthroplasty: a comparison of the 2015 and 2020 census in total joint replacement centres in Germany

There are different procedures for both, the diagnosis and the therapy of a periprosthetic joint infection (PJI), however, national or international guidelines for a standardised treatment regime are still lac...

Authors: Katrin Osmanski-Zenk, Annett Klinder, Christina Rimke, Dieter C. Wirtz, Christoph H. Lohmann, Holger Haas, Bernd Kladny and Wolfram Mittelmeier

Qualitative ultrasonography scale of the intensity of local twitch response during dry needling and its association with modified joint range of motion: a cross-sectional study

The relevance of local twitch response (LTR) during dry needling technique (DNT) is controversial, and it is questioned whether LTR is necessary for successful outcomes. Furthermore, because the LTR during the...

Authors: Carlos Cruz-Montecinos, Mauricio Cerda, Pablo Becerra, Claudio Tapia, Rodrigo Núñez-Cortés, Rodrigo Latorre-García, Sandro R. Freitas and Antonio Cuesta-Vargas

Dysregulation of ribosome-related genes in ankylosing spondylitis: a systems biology approach and experimental method

Ankylosing spondylitis (AS) is an autoimmune rheumatic disease. Few candidate gene associations have been reported for AS and the current understanding of its pathogenesis remains still poor. Thus, the exact m...

Authors: Arezou Lari, Hamid Gholami Pourbadie, Ali Sharifi-Zarchi, Maryam Akhtari, Leila Nejatbakhsh Samimi, Ahmadreza Jamshidi and Mahdi Mahmoudi

Two-staged posterior osteotomy surgery in complex and rigid congenital scoliosis in younger than 10 years old children

Congenital scoliosis caused by failure of multiply vertebral segmentation with concave fused rib or unsegmented bar combined with contralateralhemivertebra is usually rigid and produces enormous asymmetric gro...

Authors: Sheng Zhao, Xuhong Xue, Kai Li, Feng Miao and Bin Zhao

Current status survey of the extramural hospital management of venous thromboembolism after total hip and knee arthroplasty in China

Venous thromboembolism (VTE) is a potentially fatal complication after arthroplasty. Numerous prophylactic strategies and studies to reduce VTEs have focused on the duration of the hospital stay and on few ext...

Authors: Kai Tong, Hankun Liu, Jun Qin, Zhengqi Pan, Yangfan Shangguan, Hao Xiao, Hua Wang, Liaobin Chen and Yang Tan

Prevalence of and risk factors for hallux rigidus: a cross-sectional study in Japan

Hallux rigidus (HR) is a common osteoarthritis of the first metatarsophalangeal joint. However, the epidemiology and risk factors of this pathology have yet to be clarified.

Authors: Yoshiyuki Senga, Akinobu Nishimura, Naoya Ito, Yukie Kitaura and Akihiro Sudo

Increased Neck Tilt/T1 slope ratio may play an important role in patients with cervical kyphosis

In previous studies, we demonstrated that the T1 slope (T1s) is associated with clinical outcomes, but the results were not specific for individuals. A recent study suggested that an increased pelvic tilt (PT)...

Authors: Zhibin Lan, Zhiqiang Wu, Yuming Huang and Weihong Xu

Anterior prominence of the femoral condyle varies among prosthesis designs and surgical techniques in total knee arthroplasty

Patellofemoral overstuffing after total knee arthroplasty (TKA) can cause limited range of motion and anterior knee pain. This study compared anterior prominence of femoral components among different prothesis...

Authors: Junya Itou, Umito Kuwashima, Masafumi Itoh and Ken Okazaki

An individualized decision aid for physicians and patients for total knee replacement in osteoarthritis (Value-based TKR study): study protocol for a multi-center, stepped wedge, cluster randomized controlled trial

Total knee replacement (TKR) is one of the most commonly performed routine procedures in the world. Prognostic studies indicate that the number of TKR will further increase constituting growing burden on healt...

Authors: Toni Lange, Stefanie Deckert, Franziska Beyer, Waldemar Hahn, Natascha Einhart, Martin Roessler, Martin Sedlmayr, Jochen Schmitt and Jörg Lützner

Novel nomogram for predicting the progression of osteoarthritis based on 3D-MRI bone shape: data from the FNIH OA biomarkers consortium

Osteoarthritis(OA) is a major source of pain, disability, and socioeconomic cost in worldwide. However, there is no effective means for the early diagnosis of OA, nor can it accurately predict the progress of ...

Authors: Yingwei Sun, Chunbo Deng, Zhan Zhang, Xun Ma, Fenghua Zhou and Xueyong Liu

Harris Hip Score and SF-36 following metal-on-metal total hip arthroplasty and hip resurfacing - a randomized controlled trial with 5-years follow up including 75 patients

The metal-on-metal large-diameter-head (MoM-LDH) hip replacements increased in popularity during the start of the twenty-first century. Subsequently reports raised concerns regarding adverse reactions due to e...

Authors: Peter Nyby Hersnaes, Kirill Gromov, Kristian Stahl Otte, Peter Henrik Gebuhr and Anders Troelsen

The risk factors of polymicrobial periprosthetic joint infection: a single-center retrospective cohort study

Periprosthetic joint infection is a serious complication after total joint arthroplasty and polymicrobial PJI which compose a subtype of PJI often indicate worse outcomes compared to monomicrobial periprosthet...

Authors: Hao Li, Jun Fu, Erlong Niu, Wei Chai, Chi Xu, Li Bo Hao and Jiying Chen

Older fusion-surgery age in congenital scoliosis patients is a risk factor for extended length of stay, more estimated blood loss, longer fused segments and higher medical costs: a retrospective study

Contradictory opinions about whether early correction and fusion surgeries should be performed for congenital scoliosis (CS) patients at a young age exist. The objectives of this study were to analyze the asso...

Authors: Xiran Chai, Guanfeng Lin, Shengru Wang, Yang Yang, Zhe Su, You Du, Xiaolin Xu, Xiaohan Ye, Jianxiong Shen and Jianguo Zhang

Preoperative prognostic nutritional index is useful factor for predicting postoperative delirium after primary total joint arthroplasty

Postoperative delirium (PD), as an acute brain failure, is widely reported as a very common postoperative complication, and it is closely associated with increased morbidity and mortality. Recently, malnutriti...

Authors: Jie Chen, Chaojun Zheng, Jinxiu Zhong, Guanglei Zhao, Jingsheng Shi, Gangyong Huang, Yibin Wei, Siqun Wang, Jie Yu and Jun Xia

Partial uncinatectomy combined with anterior cervical discectomy and fusion for the treatment of one-level cervical radiculopathy: analysis of clinical efficacy and sagittal alignment

Biomechanical studies have demonstrated that uncovertebral joint contributes to segment mobility and stability to a certain extent. Simultaneously, osteophytes arising from the uncinate process are a common ca...

Authors: Haimiti Abudouaini, Tingkui Wu, Hao Liu, Beiyu Wang, Hua Chen, Chengyi Huang, Ying Hong and Yang Meng

Patients’ risk factors for periprosthetic joint infection in primary total hip arthroplasty: a meta-analysis of 40 studies

Periprosthetic joint infection (PJI) is a catastrophic complication after total hip arthroplasty (THA). Our meta-analysis aimed to identify the individual-related risk factors that predispose patients to PJI f...

Authors: Xiaolei Ren, Lin Ling, Lin Qi, Zhongyue Liu, Wenchao Zhang, Zhimin Yang, Wanchun Wang, Chao Tu and Zhihong Li

Closed reduction of severely angulated Rockwood and Wilkins’ type C thumb Metacarpal Base fractures in children: case series

Management of severely angulated Rockwood and Wilkins’ type C (RW-C) thumb metacarpal base fractures in children is challenging. We report experiences of percutaneous leverage reduction and dual antegrade cros...

Authors: Fei Qiao, Dehai Qu, Lei Cheng and Fei Jiang

The use of online video consultations in the aftercare of orthopedic patients: a prospective case-control study

Video consultations have proven to be an efficient source of support for patient-doctor interactions and have become increasingly used in orthopedics, especially during the COVID-19 pandemic. This study analyz...

Authors: K Estel, G Weber, F Fellmer, L Richter, S Tsitsilonis, C Willy and DA Back

Randomised, double-blind comparison of a fixed co-formulation of intra-articular polynucleotides and hyaluronic acid versus hyaluronic acid alone in the treatment of knee osteoarthritis: two-year follow-up

A first-year interim analysis of this two-year study suggested that intra-articular injections of highly purified, natural-origin polynucleotides and hyaluronic acid (HA) as a fixed combination (PNHA) might im...

Authors: Cesare Stagni, Martina Rocchi, Alessandro Mazzotta, Nicolandrea Del Piccolo, Nicola Rani, Marco Govoni, Leonardo Vivarelli, Francesca Veronesi, Milena Fini and Dante Dallari

Comparison of in vivo knee kinematics before and after bicruciate-stabilized total knee arthroplasty during squatting

No studies have directly evaluated kinematic changes during squatting before and after bicruciate-stabilized total knee arthroplasty (BCS-TKA) with the dual cam-post mechanism and asymmetric surfaces. This stu...

Authors: Masato Kiyohara, Satoshi Hamai, Hirotaka Gondo, Hidehiko Higaki, Satoru Ikebe, Ken Okazaki and Yasuharu Nakashima

Musculoskeletal pain intensity in different body regions and risk of disability pension among female eldercare workers: prospective cohort study with 11-year register follow-up

Musculoskeletal pain is a risk factor for leaving the labour market temporarily and permanently. While the presence of multi-site pain increases the risk of disability pension, we lack detailed knowledge about...

Authors: Rúni Bláfoss, Jonas Vinstrup, Sebastian Venge Skovlund, Rubén López-Bueno, Joaquin Calatayud, Thomas Clausen and Lars Louis Andersen

Interrater reliability of physical examination tests in the acute phase of shoulder injuries

The physical examination is one of the cornerstones of the diagnostic process in patients with acute shoulder injuries. The discriminative properties of a given examination test depend both on its validity and...

Authors: Malte Schmidt, Martine Enger, Are Hugo Pripp, Lars Nordsletten, Stefan Moosmayer, Knut Melhuus and Jens Ivar Brox

The association between body mass index and skin problems in persons with a lower limb amputation: an observational study

Obesity is common in persons with a lower limb amputation, an amputation can also lead to further weight gain. Data regarding the prevalence of obesity in the Dutch population with a lower limb amputation are ...

Authors: Terezka S. Mollee, Pieter U. Dijkstra, Rienk Dekker and Jan H.B. Geertzen

Mid-Term outcomes following fresh-frozen humeral head osteochondral allograft reconstruction for reverse Hill Sachs lesion: a case series

Locked posterior glenohumeral dislocations with a reverse Hill-Sachs impaction fracture involving less than 30% of the humeral head are most frequently treated with lesser tuberosity transfer into the defect, ...

Authors: Giulio Maria Marcheggiani Muccioli, Vito Gaetano Rinaldi, Giada Lullini, Alice Ritali, Massimiliano Mosca, Matteo Romagnoli, Enrico Guerra and Stefano Zaffagnini

Conventional versus helical blade screw insertion following the removal of the femoral head screw: a biomechanical evaluation using trochanteric gamma 3 locking nail versus PFN antirotation

When a hip screw needs to be changed, choosing between the conventional (C-type) and helical blade (H-type) types is difficult. In this biomechanical study, we compared these two screw types relative to the ty...

Authors: Hong Man Cho, Kwang Min Park, Tae Gon Jung, Ji Yeon Park and Young Lee

Total wrist arthrodesis with and without arthrodesis of the carpoMetacarpal joint (WAWWAM): study protocol

It is controversial whether or not the carpometacarpal joint (CMCJ) should be included in total wrist arthrodesis (TWA). Complications commonly occur at this site and studies examining its inclusion and exclus...

Authors: David H. Owen, Diana M. Perriman, Igor Policinski, Maurizio Damiani, Paul N. Smith and Chris J. Roberts

An open-label randomized multi-Centre study to evaluate anterior controllable Antedisplacement and fusion versus posterior Laminoplasty in patients with cervical ossification of the posterior longitudinal ligament: study design and analysis plan (STAR)

In treating patients with cervical ossification of the posterior longitudinal ligament (COPLL), a novel surgery technique - anterior controllable antedisplacement and fusion (ACAF) suggested promising clinical...

Authors: Yu Chen, Jingchuan Sun, Dan Han, Xiaoqiu Yuan, Yuan Wang, Yongfei Guo, Xihua Zhong and Jiangang Shi

The influence of pelvic tilt on stress distribution in the acetabulum: finite element analysis

Finite element analysis (FEA) has been previously applied for the biomechanical analysis of acetabular dysplasia and osteotomy. However, until now, there have been little reports on the use of FEA to evaluate ...

Authors: Kazuhiro Hasegawa, Tamon Kabata, Yoshitomo Kajino, Daisuke Inoue, Jiro Sakamoto and Hiroyuki Tsuchiya

Musculoskeletal symptoms and their associated risk factors among Saudi office workers: a cross-sectional study

Musculoskeletal disorders are common worldwide. Several factors are suggested in their aetiology, one of which is ergonomics alongside other individual factors. This study aims at investigating the prevalence ...

Authors: Reem S. AlOmar, Nouf A. AlShamlan, Saad Alawashiz, Yaser Badawood, Badr A. Ghwoidi and Hassan Abugad

The relationship between readiness to change pain-related exercise participation and perceived work ability: a cross-sectional study of factory workers

Healthy lifestyle behaviours are associated with protection against health disorders and pain. Exercise participation is one such behaviour, associated with improved outcomes in those experiencing pain. Muscul...

Authors: Paul Shawcross, Melinda Lyons and Victoria Filingeri

Radiographic and clinical outcomes of surgical treatment of Kümmell’s disease with thoracolumbar kyphosis: a minimal two-year follow-up

Up to now in the surgical treatment of Kümmell’s disease combined with thoracolumbar kyphosis, little research has focused on the evaluation of the imaging and clinical outcomes of restoring the normal alignme...

Authors: Hao Cheng, Guo-dong Wang, Tao Li, Xiao-yang Liu and Jian-min Sun

The association between acromial anatomy and articular-sided partial thickness of rotator cuff tears

Acromial anatomy has been found to be correlated with degenerative full-thickness rotator cuff tears in current studies. However, research on the relationship between acromial anatomy and articular-sided parti...

Authors: Cen Tao Liu, Jia Qing Miao, Hua Wang, Heng an Ge, Xian Hui Wang and Biao Cheng

Association between lipid biomarkers and osteoporosis: a cross-sectional study

Osteoporosis and cardiovascular diseases (CVDs) are 2 major public health problems. Osteoporosis and CVDs may be linked but the association between lipid profile and osteoporosis is still controversial. The pu...

Authors: Bo Kan, Qianqian Zhao, Lijuan Wang, Shanshan Xue, Hanqing Cai and Shuman Yang

Modified F configuration in the treatment of Pauwels type III femoral neck fracture: a finite element analysis

The optimal treatment of Pauwels type III femoral neck fracture (FNF) in young patients remains a worldwide challenge in orthopedic surgery.

Authors: Shiyuan Lin, Jie Shang, Baizhou Xing, Biao Wu, Rong Peng, Gang Wang and Hua-Ding Lu

Vertebral fracture as a risk factor for self-harm: a retrospective cohort study

The prevention of self-harm is an international public health priority. It is vital to identify at-risk populations, particularly as self-harm is a risk factor for suicide. This study aims to examine the risk ...

Authors: James A. Prior, Fay Crawford-Manning, Rebecca Whittle, Alyshah Abdul-Sultan, Carolyn A. Chew-Graham, Sara Muller, Tom A. Shepherd, Athula Sumathipala, Christian D. Mallen and Zoe Paskins

Differences in myoelectric activity of the lumbar muscles between recurrent and chronic low back pain: a cross-sectional study

Altered lower back muscle activity is proposed as a contributing factor to the reoccurrence and chronicity of low back pain (LBP). This study compared lumbar muscle activity during trunk extension in patients ...

Authors: Mercè Balasch-Bernat, Tine Willems, Lieven Danneels, Mira Meeus and Dorien Goubert

Differentiating migraine, cervicogenic headache and asymptomatic individuals based on physical examination findings: a systematic review and meta-analysis

Migraine and cervicogenic headache (CGH) are common headache disorders, although the large overlap of symptoms between them makes differential diagnosis challenging. To strengthen differential diagnosis, physi...

Authors: E. Anarte-Lazo, G. F. Carvalho, A. Schwarz, K. Luedtke and D. Falla

Perceptions, beliefs, and needs of Japanese people with knee osteoarthritis during conservative care: a qualitative study

Patients’ perceptions and beliefs of disease could be influenced by their lifestyle and culture. Although it is important to understand their perceptions and beliefs toward disease to prevent and manage osteoa...

Authors: Daisuke Uritani, Akane Ikeda, Toru Shironoki, Kentaro Matsubata, Yuto Mutsura, Tadashi Fujii and Koji Ikeda

Comparing post-operative pain between single bundle and double bundle anterior cruciate ligament reconstruction: a retrospective study

In anterior cruciate ligament (ACL) reconstruction, the clinical outcome and level of post-operative pain are important factors. To date there have been no studies evaluating differences in post-operative pain...

Authors: Chaiwat Chuaychoosakoon, Wachiraphan Parinyakhup, Arnan Wiwatboworn, Peeranut Purngpiputtrakul, Pawin Wanasitchaiwat and Tanarat Boonriong

Correction to: Conservative versus surgical management for patients with rotator cuff tears: a systematic review and META-analysis

Authors: Umile Giuseppe Longo, Laura Risi Ambrogioni, Vincenzo Candela, Alessandra Berton, Arianna Carnevale, Emiliano Schena and Vincenzo Denaro

Prevalence and incidence of work-related musculoskeletal disorders in secondary industries of 21st century Europe: a systematic review and meta-analysis

Over the course of the twenty-first century, work-related musculoskeletal disorders are still persisting among blue collar workers. At present, no epidemiological overview exists. Therefore, a systematic revie...

Authors: Renée Govaerts, Bruno Tassignon, Jo Ghillebert, Ben Serrien, Sander De Bock, Toon Ampe, Ilias El Makrini, Bram Vanderborght, Romain Meeusen and Kevin De Pauw

Technique and results after immediate orthotopic replantation of extracorporeally irradiated tumor bone autografts with and without fibular augmentation in extremity tumors

Reconstruction of the skeletal defects resulting from the resection of bone tumors remains a considerable challenge and one of the possibilities is the orthotopic replantation of the irradiated bone autograft....

Authors: Alexander Klein, Yasmin Bakhshai, Falk Roeder, Christof Birkenmaier, Andrea Baur-Melnyk and Hans Roland Dürr

Retear rates after rotator cuff surgery: a systematic review and meta-analysis

Rotator cuff retear (RCR) is one of the main postoperative drawbacks. RCR can be considered a multifactorial issue, which causes are related either to biological than biomechanical factors. The aim of this stu...

Authors: Umile Giuseppe Longo, Arianna Carnevale, Ilaria Piergentili, Alessandra Berton, Vincenzo Candela, Emiliano Schena and Vincenzo Denaro

Treatment of Fabella syndrome with arthroscopic fabellectomy: a case series and literature review

The fabella is a sesamoid bone in the posterolateral capsule of the human knee joint. In quadrupedal mammals, the fabella is believed to have a role similar to the patella in redirecting extension forces of th...

Authors: Shuo-Po Weng, Tsung-Mu Wu, Chi-Sheng Chien and Sheng-Hui Lin

Evaluation of three methods of suture for skin closure in total knee arthroplasty: a randomized trial

There are several studies comparing techniques and different materials, yet the results are not unanimous. We compared three methods of skin closure in total knee arthroplasty (TKA), including suture with sing...

Authors: Rodrigo Barreiros Vieira, Gustavo Waldolato, João Sequeira Fernandes, Thiago Gontijo de Carvalho, Pedro Augusto Maciel Moreira, Guilherme Barbosa Moreira and Jorge Suman Vieira

The ideal mHealth-application for rheumatoid arthritis: qualitative findings from stakeholder focus groups

Shifts in treatment strategies for rheumatoid arthritis (RA) have made ambulatory care more labour-intensive. These developments have prompted innovative care models, including mobile health (mHealth) applicat...

Authors: Michaël Doumen, René Westhovens, Sofia Pazmino, Delphine Bertrand, Veerle Stouten, Claudia Neys, Nelly Creten, Els Van Laeken, Patrick Verschueren and Diederik De Cock

Anterior reduction and C1-ring osteosynthesis with Jefferson-fracture reduction plate (JeRP) via transoral approach for unstable atlas fractures

To introduce a novel transoral instrumentation in the treatment of unstable fractures of the atlas.

Authors: Qiang Tu, Hu Chen, Zhan Li, Yuyue Chen, Aihong Xu, Changrong Zhu, Xianhua Huang, Xiangyang Ma, Jianhua Wang, Kai Zhang, Qingshui Yin, Jianzhong Xu and Hong Xia

Radiological and mid- to long-term patient-reported outcome after stabilization of traumatic thoraco-lumbar spinal fractures using an expandable vertebral body replacement implant

For the treatment of unstable thoraco-lumbar burst fractures, a combined posterior and anterior stabilization instead of a posterior-only instrumentation is recommend in the current literature due to the insta...

Authors: Siegmund Lang, Carsten Neumann, Christina Schwaiger, Andreas Voss, Volker Alt, Markus Loibl and Maximilian Kerschbaum

Customized treatment protocols for patients with closed fracture in hospitals at varying coronavirus disease 2019 (COVID-19) risk

To determine an optimized treatment protocol during the COVID-19 epidemic for patients with closed fracture and delayed surgery.

Authors: Yu He, Zhong-Hua Guo, Yong-Guang Wu, Rui Li, Xie Xie and De-Hao Fu