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  1. Long-term patients with diabetes and peripheral neuropathy show altered foot biomechanics and abnormal foot loading. This study aimed at assessing muscle performance and ankle mobility in such patients under c...

    Authors: Claudia Giacomozzi, Emanuela D'Ambrogi, Stefano Cesinaro, Velio Macellari and Luigi Uccioli

    Citation: BMC Musculoskeletal Disorders 2008 9:99

    Content type: Research article

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  2. Tibial Tubercle Osteotomy has shown much promise in revision total knee replacement. Methods of repair previously described include screw and wire fixation. Both methods have significant complications.

    Authors: Crawford R Deane, Nicholas A Ferran, Adel Ghandour and Rhidian L Morgan-Jones

    Citation: BMC Musculoskeletal Disorders 2008 9:98

    Content type: Technical advance

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  3. The causes of chronic low back pain (CLBP) remain obscure and effective treatment of symptoms remains elusive. A mechanism of relieving chronic pain based on the consequences of conflicting unpleasant sensory ...

    Authors: Karen L Barker, Christopher J Elliott, Catherine M Sackley and Jeremy CT Fairbank

    Citation: BMC Musculoskeletal Disorders 2008 9:97

    Content type: Research article

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  4. The aim of this study was to determine the prevalence and the predictors of musculoskeletal symptoms in the upper extremities and neck at visual display terminal (VDT) workstations.

    Authors: André Klussmann, Hansjuergen Gebhardt, Falk Liebers and Monika A Rieger

    Citation: BMC Musculoskeletal Disorders 2008 9:96

    Content type: Research article

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  5. This study aims to contribute to the knowledge of the influence of comorbidity in OA. The objectives of the study were (i) to describe the prevalence of comorbidity and (ii) to describe the relationship betwee...

    Authors: Gabriella M van Dijk, Cindy Veenhof, Francois Schellevis, Harry Hulsmans, Jan PJ Bakker, Henk Arwert, Jos HM Dekker, Guus J Lankhorst and Joost Dekker

    Citation: BMC Musculoskeletal Disorders 2008 9:95

    Content type: Research article

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  6. Animal models have provided much information on molecular and cellular changes in joint disease, particularly OA. However there are limitations to in vivo work and single tissue in vitro studies can provide more ...

    Authors: Frances MD Henson and Thea A Vincent

    Citation: BMC Musculoskeletal Disorders 2008 9:94

    Content type: Research article

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  7. Two types of methods are used to assess learning curves: outcome assessment and process assessment. Outcome measures are usually dichotomous rare events like complication rates and survival or require an exten...

    Authors: Jakob van Oldenrijk, Matthias U Schafroth, Mohit Bhandari, Wouter C Runne and Rudolf W Poolman

    Citation: BMC Musculoskeletal Disorders 2008 9:93

    Content type: Study protocol

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  8. Little is known about the course of Complex Regional Pain Syndrome 1 and potential factors influencing the course of this disorder over time. The goal of this study is a) to set up a database with patients suf...

    Authors: Florian Brunner, Lucas M Bachmann, Ulrich Weber, Alfons GH Kessels, Roberto SGM Perez, Johan Marinus and Rudolf Kissling

    Citation: BMC Musculoskeletal Disorders 2008 9:92

    Content type: Study protocol

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  9. Persistent whiplash associated disorders (WAD) have been associated with alterations in kinesthetic sense and motor control. The evidence is however inconclusive, particularly for differences between WAD patie...

    Authors: Astrid Woodhouse and Ottar Vasseljen

    Citation: BMC Musculoskeletal Disorders 2008 9:90

    Content type: Research article

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  10. Parameters of MR imaging play a pivotal role in diagnosing lumbar spinal stenosis (LSS), and serve as an important tool in clinical decision-making. Despite the importance of MR imaging, little is known about ...

    Authors: Felix Zeifang, Marcus Schiltenwolf, Rainer Abel and Babak Moradi

    Citation: BMC Musculoskeletal Disorders 2008 9:89

    Content type: Research article

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  11. Initial promise of a stand-alone interbody fusion cage to treat chronic back pain and restore disc height has not been realized. In some instances, a posterior spinal fixation has been used to enhance stabilit...

    Authors: Shih-Hao Chen, Ching-Lung Tai, Chien-Yu Lin, Pang-Hsing Hsieh and Weng-Pin Chen

    Citation: BMC Musculoskeletal Disorders 2008 9:88

    Content type: Research article

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  12. Čobeljić et al. recently reported a numeric table method to provide precise rotational osteotomy which is a well established orthopaedic procedure. The numeric table requires four pages in length that is rathe...

    Authors: Chen-Kun Liaw, Rong-Sen Yang, Sheng-Mou Hou, Tai-Yin Wu and Chiou-Shann Fuh

    Citation: BMC Musculoskeletal Disorders 2008 9:87

    Content type: Correspondence

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  13. Autologous chondrocyte implantation is an established technique for the repair of degenerated articular cartilage. Recently, the detection of side population (SP) cells, which have the ability to strongly effl...

    Authors: Takeshi Teramura, Kanji Fukuda, Shinji Kurashimo, Yoshihiko Hosoi, Yoshihisa Miki, Shigeki Asada and Chiaki Hamanishi

    Citation: BMC Musculoskeletal Disorders 2008 9:86

    Content type: Research article

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  14. Mounting evidence supports a physiological role for silicon (Si) as orthosilicic acid (OSA, Si(OH)4) in bone formation. The effect of oral choline-stabilized orthosilicic acid (ch-OSA) on markers of bone turnover...

    Authors: Tim D Spector, Mario R Calomme, Simon H Anderson, Gail Clement, Liisa Bevan, Nathalie Demeester, Rami Swaminathan, Ravin Jugdaohsingh, Dirk A Vanden Berghe and Jonathan J Powell

    Citation: BMC Musculoskeletal Disorders 2008 9:85

    Content type: Research article

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  15. The association of lumbar spine instability between laminectomy and laminotomy has been clinically studied, but the corresponding in vitro biomechanical studies have not been reported. We investigated the hypothe...

    Authors: Ching-Lung Tai, Pang-Hsing Hsieh, Weng-Pin Chen, Lih-Huei Chen, Wen-Jer Chen and Po-Liang Lai

    Citation: BMC Musculoskeletal Disorders 2008 9:84

    Content type: Research article

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  16. A recent study of adults aged ≥50 years reporting knee pain found an excess of radiographic knee osteoarthritis (knee ROA) in symptomatic males compared to females. This was independent of age, BMI and other c...

    Authors: Rosie J Lacey, Elaine Thomas, Rachel C Duncan and George Peat

    Citation: BMC Musculoskeletal Disorders 2008 9:82

    Content type: Research article

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  17. There is little evidence on differences across health care systems in choice and outcome of the treatment of chronic low back pain (CLBP) with spinal surgery and conservative treatment as the main options. At ...

    Authors: Markus Melloh, Christoph Röder, Achim Elfering, Jean-Claude Theis, Urs Müller, Lukas P Staub, Emin Aghayev, Thomas Zweig, Thomas Barz, Thomas Kohlmann, Simon Wieser, Peter Jüni and Marcel Zwahlen

    Citation: BMC Musculoskeletal Disorders 2008 9:81

    Content type: Study protocol

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  18. The cervical multifidus muscles insert onto the lower cervical facet capsular ligaments and the cervical facet joints are the source of pain in some chronic whiplash patients. Reflex activation of the multifid...

    Authors: Gunter P Siegmund, Jean-Sébastien Blouin, Mark G Carpenter, John R Brault and J Timothy Inglis

    Citation: BMC Musculoskeletal Disorders 2008 9:80

    Content type: Research article

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  19. In Sweden, as well as in Scandinavia, there is no easy way to evaluate patients' difficulties when they suffer from lateral epicondylitis/epicondylalgia. However, there is a Canadian questionnaire, in English,...

    Authors: Pia Nilsson, Amir Baigi, Bertil Marklund and Jörgen Månsson

    Citation: BMC Musculoskeletal Disorders 2008 9:79

    Content type: Research article

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  20. Rotator cuff tears are frequently associated with pathologies of the long head of the biceps tendon (LHBT). Tenotomy and tenodesis of the LHBT are commonly used to manage disorders of the LHBT.

    Authors: Francesco Franceschi, Umile Giuseppe Longo, Laura Ruzzini, Giacomo Rizzello, Nicola Maffulli and Vincenzo Denaro

    Citation: BMC Musculoskeletal Disorders 2008 9:78

    Content type: Technical advance

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  21. Non-steroidal anti-inflammatory drugs (NSAIDs) are recommended for multimodal postoperative pain management. We evaluated opioid-sparing effects and rehabilitative results after perioperative celecoxib adminis...

    Authors: Yu-Min Huang, Chiu-Meng Wang, Chen-Ti Wang, Wei-Peng Lin, Lih-Ching Horng and Ching-Chuan Jiang

    Citation: BMC Musculoskeletal Disorders 2008 9:77

    Content type: Research article

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  22. Recent reviews have indicated that low level level laser therapy (LLLT) is ineffective in lateral elbow tendinopathy (LET) without assessing validity of treatment procedures and doses or the influence of prior...

    Authors: Jan M Bjordal, Rodrigo AB Lopes-Martins, Jon Joensen, Christian Couppe, Anne E Ljunggren, Apostolos Stergioulas and Mark I Johnson

    Citation: BMC Musculoskeletal Disorders 2008 9:75

    Content type: Research article

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  23. Rheumatoid arthritis (RA) is a chronic auto-immune disease with extensive articular cartilage destruction. Aggrecan depletion, mediated by aggrecanases is one of the first signs of early cartilage erosion. We ...

    Authors: Jean C Rousseau, Eren U Sumer, Gert Hein, Bodil C Sondergaard, Suzi H Madsen, Christian Pedersen, Thomas Neumann, Andreas Mueller, Per Qvist, Pierre Delmas and Morten A Karsdal

    Citation: BMC Musculoskeletal Disorders 2008 9:74

    Content type: Research article

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  24. Previous studies from our group have shown that a high prevalence of vertebral deformities suggestive of fracture can be found in patients with an inflammatory disease, despite a near normal bone mineral densi...

    Authors: A Caroline Heijckmann, Bianca Dumitrescu, Arie C Nieuwenhuijzen Kruseman, Piet Geusens, Bruce HR Wolffenbuttel, Jolanda De Vries, Marjolein Drent and Maya SP Huijberts

    Citation: BMC Musculoskeletal Disorders 2008 9:72

    Content type: Research article

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  25. There is strong evidence that athletes have a twofold risk for re-injury after a previous ankle sprain, especially during the first year post-injury. These ankle sprain recurrences could result in disability a...

    Authors: Maarten DW Hupperets, Evert ALM Verhagen and Willem van Mechelen

    Citation: BMC Musculoskeletal Disorders 2008 9:71

    Content type: Study protocol

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  26. It is recognized that different types of hallux valgus exist. Classification occurs with radiographic and clinical parameters. Severity of different parameters is used in algorithms to choose between different...

    Authors: Axel R Deenik, Enrico de Visser, Jan-Willem K Louwerens, Maarten de Waal Malefijt, Frits F Draijer and Rob A de Bie

    Citation: BMC Musculoskeletal Disorders 2008 9:70

    Content type: Research article

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  27. Some studies have raised the question about whether the good results obtained with the Charnley prosthesis could be replicated at general hospitals when it comes to the frequency of early complications and fai...

    Authors: Daniel Hernández-Vaquero, Abelardo Suárez-Vazquez and Jesus Fernandez-Lombardia

    Citation: BMC Musculoskeletal Disorders 2008 9:69

    Content type: Research article

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  28. Self-report questionnaires play an important role as outcome measures in shoulder research. Having an estimate of the measurement error of these questionnaires is of importance when assessing follow-up results...

    Authors: Ole M Ekeberg, Erik Bautz-Holter, Einar K Tveitå, Anne Keller, Niels G Juel and Jens I Brox

    Citation: BMC Musculoskeletal Disorders 2008 9:68

    Content type: Research article

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  29. Percutaneous vertebroplasty (PV) is generally performed under fluoroscopic guidance. Technically, single fluoroscope is considered sufficient for effectively monitoring PV. However, single fluoroscopic techniq...

    Authors: Yen-Yao Li, Tsung-Jen Huang, Chin-Chang Cheng and Robert Wen-Wei Hsu

    Citation: BMC Musculoskeletal Disorders 2008 9:67

    Content type: Technical advance

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  30. Osteolytic metastases around the acetabulum are frequent in tumour patients, and may cause intense and drug-resistant pain of the hip. These lesions also cause structural weakening of the pelvis, limping, and ...

    Authors: Giulio Maccauro, Francesco Liuzza, Laura Scaramuzzo, Alessandro Milani, Francesco Muratori, Barbara Rossi, Victor Waide, Giandomenico Logroscino, Carlo A Logroscino and Nicola Maffulli

    Citation: BMC Musculoskeletal Disorders 2008 9:66

    Content type: Technical advance

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  31. Chronic low back pain remains a major health problem in Australia and around the world. Unfortunately the majority of treatments for this condition produce small effects because not all patients respond to eac...

    Authors: Luciana G Macedo, Jane Latimer, Chris G Maher, Paul W Hodges, Michael Nicholas, Lois Tonkin, James H McAuley and Ryan Stafford

    Citation: BMC Musculoskeletal Disorders 2008 9:65

    Content type: Study protocol

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  32. Anterior knee pain (AKP) is a common musculoskeletal complaint. It has been suggested that one factor that may contribute to the presence of AKP is a delay in the recruitment of the vastus medialis oblique mus...

    Authors: Rachel Chester, Toby O Smith, David Sweeting, John Dixon, Sarah Wood and Fujian Song

    Citation: BMC Musculoskeletal Disorders 2008 9:64

    Content type: Research article

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  33. Fatigue is recognized as a disabling symptom in many chronic conditions including rheumatic disorders such as rheumatoid arthritis (RA) and lupus. Fatigue in osteoarthritis (OA) is not routinely evaluated and ...

    Authors: J Denise Power, Elizabeth M Badley, Melissa R French, Angela J Wall and Gillian A Hawker

    Citation: BMC Musculoskeletal Disorders 2008 9:63

    Content type: Research article

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  34. Splinting as part of the overall post-surgical management of patients after release of Dupuytren's contracture has been widely reported, though there is variation in practice and criteria for using it. The evi...

    Authors: Christina Jerosch-Herold, Lee Shepstone, Adrian J Chojnowski and Debbie Larson

    Citation: BMC Musculoskeletal Disorders 2008 9:62

    Content type: Study protocol

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  35. Low back pain (LBP) is a frequent health complaint among health care personnel. Several work tasks and working postures are associated with an increased risk of LBP. The aim of this study was to compare two se...

    Authors: Kirsten Nabe-Nielsen, Nils Fallentin, Karl B Christensen, Jette N Jensen and Finn Diderichsen

    Citation: BMC Musculoskeletal Disorders 2008 9:61

    Content type: Research article

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  36. Adequate and intensive rehabilitation is an important requirement for successful total knee arthroplasty.

    Authors: Ton AF Lenssen, Mike JA van Steyn, Yvonne HF Crijns, Eddie MH Waltjé, George M Roox, Ruud JT Geesink, Piet A van den Brandt and Rob A De Bie

    Citation: BMC Musculoskeletal Disorders 2008 9:60

    Content type: Research article

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  37. In Denmark, approximately 12,000 hip and knee arthroplasties were performed in 2006, and the hospital costs were close to US$ 110,000,000. In a randomized clinical trial, we have recently demonstrated the effi...

    Authors: Kristian Larsen, Karen Elisabeth Hvass, Torben B Hansen, Per B Thomsen and Kjeld Søballe

    Citation: BMC Musculoskeletal Disorders 2008 9:59

    Content type: Research article

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  38. Back pain is a major health problem and many sufferers develop persistent symptoms. Detecting relevant subgroups of patients with non-specific low back pain has been highlighted as a priority area for research...

    Authors: Elaine M Hay, Kate M Dunn, Jonathan C Hill, Martyn Lewis, Elizabeth E Mason, Kika Konstantinou, Gail Sowden, Simon Somerville, Kanchan Vohora, David Whitehurst and Chris J Main

    Citation: BMC Musculoskeletal Disorders 2008 9:58

    Content type: Study protocol

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  39. Major shoulder surgery often results in severe post-operative pain and a variety of interventions have been developed in an attempt to address this. The continuous slow infusion of a local anaesthetic directly...

    Authors: Jennifer A Coghlan, Andrew Forbes, Simon N Bell and Rachelle Buchbinder

    Citation: BMC Musculoskeletal Disorders 2008 9:56

    Content type: Study protocol

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  40. Cutpoints (CPs) for mild, moderate and severe pain are established and used primarily in cancer pain. In this study, we wanted to determine the optimal CPs for mild, moderate, and severe pain in joint replacem...

    Authors: Heidi Kapstad, Berit R Hanestad, Norvald Langeland, Tone Rustøen and Knut Stavem

    Citation: BMC Musculoskeletal Disorders 2008 9:55

    Content type: Research article

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  41. Low-back pain is responsible for significant disability and costs in industrialized countries. Only a minority of subjects suffering from low-back pain will develop persistent disability. However, this minorit...

    Authors: Stéphane Poitras, Michel Rossignol, Clermont Dionne, Michel Tousignant, Manon Truchon, Bertrand Arsenault, Pierre Allard, Manon Coté and Alain Neveu

    Citation: BMC Musculoskeletal Disorders 2008 9:54

    Content type: Research article

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  42. Hydrodilatation of the glenohumeral joint is by several authors reported to improve shoulder pain and range of motion for patients with adhesive capsulitis. Procedures described often involve the injection of ...

    Authors: Einar Kristian Tveitå, Rana Tariq, Sølve Sesseng, Niels Gunnar Juel and Erik Bautz-Holter

    Citation: BMC Musculoskeletal Disorders 2008 9:53

    Content type: Research article

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  43. To analyse available evidence on the efficacy and safety of anti-TNFα drugs (infliximab, etanercept and adalimumab) for treating rheumatoid arthritis (RA).

    Authors: Alberto Alonso-Ruiz, Jose Ignacio Pijoan, Eukene Ansuategui, Arantxa Urkaregi, Marcelo Calabozo and Antonio Quintana

    Citation: BMC Musculoskeletal Disorders 2008 9:52

    Content type: Research article

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  44. Modic changes are bone marrow lesions visible in magnetic resonance imaging (MRI), and they are assumed to be associated with symptomatic intervertebral disc disease, especially changes located at L5-S1. Only ...

    Authors: Mari Kuisma, Jaro Karppinen, Marianne Haapea, Jaakko Niinimäki, Risto Ojala, Markku Heliövaara, Raija Korpelainen, Kaisu Kaikkonen, Simo Taimela, Antero Natri and Osmo Tervonen

    Citation: BMC Musculoskeletal Disorders 2008 9:51

    Content type: Research article

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  45. Despite emphasis on patient centred healthcare, healthcare professionals have been slow to use validated measurements of patient satisfaction in physiotherapy practice. The aim of this cross sectional survey w...

    Authors: Sarah N Casserley-Feeney, Martin Phelan, Fionnuala Duffy, Susan Roush, Melinda C Cairns and Deirdre A Hurley

    Citation: BMC Musculoskeletal Disorders 2008 9:50

    Content type: Research article

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