Fig. 1
From: FTH1 protects against osteoarthritis by MAPK pathway inhibition of extracellular matrix degradation
Loss of chondrocytes expressing FTH1 in OA patients and DMM mice. A Safranin O and Fast Green staining (upper row) and immunostaining of FTH1 (lower row) of OA cartilage. Scale bar: 400 µm(upper row) and 200 µm(lower row); B Safranin O and Fast Green staining (upper row) and immunostaining of FTH1 (lower row) of DMM mice cartilage. Scale bar: 200 µm; C Percentage of positive cells of FTH1 in human OA cartilage. n = 5 per group; D Percentage of positive cells of FTH1 in DMM mice cartilage n = 5 per group; E Immunoblotting of FTH1 in primary murine chondrocytes which treated with 5 ng/ml IL-1βfor 48 h