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Fig. 5 | BMC Musculoskeletal Disorders

Fig. 5

From: Bone marrow mesenchymal stem cell-derived exosomes promote osteoblast proliferation, migration and inhibit apoptosis by regulating KLF3-AS1/miR-338-3p

Fig. 5

Effects of miR-338-3p in MC3T3-E1 cells incubated with BMSCs-Exo. (A) Transfection of miR-338-3p inhibitors down-regulated the expression level of miR-338-3p in BMSCs-Exo incubated MC3T3-E1 cells. The decrease of miR-338-3p can promote the (B) viability and (C) migration of BMSCs-Exo incubated MC3T3-E1 cells, and inhibit (D) cell apoptosis. ***p < 0.001 vs. Control group; ##p < 0.01, ###p < 0.001 vs. BMSC-Exos + si-NC group; &p < 0.05, &&p < 0.01, &&&p < 0.001 vs. BMSC-Exos + si-KLF3-AS1 + inhibitor-NC group (n = 5, one-way ANOVA).

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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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