Table 2 Univariate analyses between different variables and LS BMD change at 12 months

Estimate

P value

Estimate

P value

Age

0.001945

0.451

Smoking

-0.28717

0.000461***

Age of menopause

-0.01268

0.2181

Tea

-0.20749

0.0343*

BMI

-0.005369

0.47283

Coffee

-0.18500

0.0574

Previous osteoporosis fracture

0.009811

0.842

Alcohol

-0.20109

0.0243*

Gastrointestinal disease

-0.22190

0.0048**

Western Diet^a

-0.0008772

0.98900

Hypertension

0.01267

0.799

Asian Diet^a

-0.0446272

0.42381

Diabetes

-0.07522

0.288

Vegetarian Diet^a

-0.2549002

0.00145**

Bisphosphonates

-0.27827

0.00438**

Exercise

-0.03574

0.257

Glucocorticoid

-0.21174

0.00395**

ALT

-0.003383

0.0832

Menatetrenone/Vit K2

0.14386

0.0217*

AST

-0.001340

0.55

25(OH)D level at baseline

0.015260

4.95e-07***

TG

-0.01010

0.617

PINP level at baseline

0.0017412

0.0804

UA

9.443e-05

0.742

β-CTX level at baseline

0.09458

0.27

Creatine

-0.001141

0.4

PINP increment (3 month)

0.0027323

9.76e-12***

BMD at baseline

-0.13610

1.45e-08***

β-CTX increment (3 month)

0.21086

0.00451**