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Table 2 Sensitivity analysis of the Mendelian randomization (MR) analysis results of DM2 and BMD

From: Association of type 2 Diabetes Mellitus and bone mineral density: a two-sample Mendelian randomization study

Exposure

 

DM2

Outcome

TB-BMD

FN-BMD

UF-BMD

H-BMD

LS-BMD

IVW (heterogeneity)

p value

0.35

0.18

0.79

0.15

0.09

 

Q

253.22

92.52

166.64

1551.69

98.29

MR Egger (heterogeneity)

p value

0.47

0.16

0.09

0.28

0.14

 

Q

252.81

92.48

166.51

1563.14

93.75

MR Egger (pleiotropy)

p value

0.66

0.86

0.76

0.35

0.05

 

intercept

0.002

0.002

0.003

0.002

0.005

  1. Note: DM2 Type 2 Diabetes Mellitus, MR Mendelian randomization, TB Total body, FN, Femoral neck, UF, Ultradistal forearm, LS, Lumbar spine, BMD Bone mineral density, IVW inverse variance weighting, OR odds ratio, CI confidence interval
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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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