Table 1 The overall of 6 cases results
Case | Sex | Age | Causative bacteria | The time after TKA(m) | CLAP therapy | iJAP(d) | iMAP(d) | GM (mg/day) | GM max blood concentration (μ/dL) | Follow up period(m) | Intravenous antibacterial usage time(d) | Oral antibacterial usage time(m) | Results |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | M | 84 | MSSA | 33 | 1st | 17 | 5 | 120 | 1.5 | (-) | MEPM(12d) | MINO(1w) | Recurrence (2.5M) |
(-) | 2nd | 19 | 7 | 160 | 2.1 | 36 | CEZ(16d) | RFP,MINO(12m) | Remission | ||||
2 | F | 81 | E. coli | 125 | 1st | 16 | 16 | 200 | 5 | 26 | CMZ(35d) | CCL,MINO(3m) | Remission |
3 | F | 94 | MSSA | 219 | 1st | 15 | (-) | 80 | 0.3 | 12 | CEZ(14d) | MINO(3m) | Remission |
4 | F | 70 | MSSA, Streptococcus dysgalactiae | 75 | 1st | 21 | (-) | 200 | 0.4 | 22 | ABPC&CLDM(7d) CTRX(14d) | ABPC (4m) | Remission |
5 | F | 73 | Klebsiella pneumoniae | 17 | 1st | 28 | (-) | 120 | 0.5 | (-) | CTRX(7d) CEZ(24d) | CCL(3m) | Recurrence (5M) |
(-) | 2nd | 21 | 12 | 240 | 1.0 | 32 | CEZ(14d) | CCL,MINO(9m) | Remission | ||||
6 | F | 75 | Unknown | 93 | 1st | 17 | (-) | 180 | 0.2 | 18 | CEZ(17d) | ST, MINO(8m) | Remission |
Avg | Â | 79.5 | Â | 93.7 | Â | 19.3 | 10.0 | 162.5 | 1.4 | 24.3 | Â | Â | Â |