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Table 5 Risk of fracture considering exposure to renin-angiotensin system inhibitors in subgroups

From: The impact of Renin-Angiotensin System Inhibitors on bone fracture risk: a nationwide nested case-control study

Variables

Fracture case

Controls

Conditional logistic regression

(n = 1,049)

(n = 1,049)

n

%

n

%

OR (95% CI)

P-value

Diabetes

Never-user

215

52.7

193

47.3

  

Ever-user

135

47.5

149

52.5

0.81 (0.49–1.35)

0.415

No diabetes

Never-user

604

50.8

585

49.2

  

Ever-user

95

43.8

122

56.2

0.74 (0.51–1.07)

0.108

No stroke

Never-user

811

51.2

773

48.8

  

Ever-user

223

45.7

265

54.3

0.73 (0.58–0.91)

0.005

BMI ≥ 23 kg/m2

Never-user

427

51.9

396

48.1

  

Ever-user

159

45.8

188

54.2

0.65 (0.46–0.91)

0.013

Statins

Never-user

66

50.8

64

49.2

  

Ever-user

92

48.4

98

51.6

0.62 (0.47–0.83)

0.001

No statins

Never-user

392

50.6

382

49.4

  

Ever-user

71

46.1

83

53.9

0.61 (0.35–1.05)

0.074

  1. Abbreviations: BMI Body mass index