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Table 2 Comparison of the mean Hb between the three study groups at three time-points

From: Comparison of the effect of combined administration of intravenous and intra-articular tranexamic acid versus their administration alone in the management of blood loss in total knee arthroplasty: a prospective, multicenter study in Iran

Time-point

Group

P-value

IV group (nā€‰=ā€‰108)

IA group (nā€‰=ā€‰92)

Combined group (nā€‰=ā€‰86)

Preoperative Hb (mg/dl)

13.21ā€‰Ā±ā€‰1.4

13.5ā€‰Ā±ā€‰1.5

13.48ā€‰Ā±ā€‰1.3

0.89

Hb of 12Ā h after the surgery(mg/dl)

11.95ā€‰Ā±ā€‰1.5

11.84ā€‰Ā±ā€‰1.6

12.01ā€‰Ā±ā€‰1.5

0.88

Hb of 24Ā h after the surgery

10.53ā€‰Ā±ā€‰1.7

10.49ā€‰Ā±ā€‰1.6

10.67ā€‰Ā±ā€‰1.4

0.28

Hb of 3 days after surgery (mg/dl)

9.21ā€‰Ā±ā€‰1.8

9.58ā€‰Ā±ā€‰2.68

11.08ā€‰Ā±ā€‰1.28

0.001

Total blood loss (ml)

1611.2ā€‰Ā±ā€‰401.1

1601.6ā€‰Ā±ā€‰392.2

1256.4ā€‰Ā±ā€‰331.1

0.025

  1. HbĀ Hemoglobin; IVĀ Intravenous; IAĀ Intra-articular
  2. Repeated measures ANOVA test was used to compare the level of variables at different times in three groups