Table 1 Patient demographics and comorbidities for patients with preoperative normal APRI, some liver damage, significant fibrosis, and cirrhosis. Bold p-values indicate statistical significance with p < 0.05

Overall

103,678

444

256

253

Sex

 < 0.001

 < 0.001

0.004

 Female

57,004 (55.0)

194 (43.7)

105 (41.0)

116 (45.8)

 Male

46,674 (45.0)

250 (56.3)

151 (59.0)

137 (54.2)

Age

 < 0.001

 < 0.001

 < 0.001

 18–39

2,164 (2.1)

12 (2.7)

7 (2.7)

8 (3.2)

 40–64

44,341 (42.8)

254 (57.3)

159 (62.4)

147 (58.1)

 65–74

34,941 (33.7)

114 (25.7)

56 (22.0)

61 (24.1)

  ≥ 75

22,134 (21.4)

63 (14.2)

33 (12.9)

37 (14.6)

BMI (kg/m^2)

0.031

0.176

0.002

  < 18.5

985 (1.0)

8 (1.8)

3 (1.2)

3 (1.2)

 18.5–29.9

19,443 (18.8)

100 (22.5)

60 (23.4)

72 (28.5)

 30–34.9

33,962 (32.8)

123 (27.7)

89 (34.8)

80 (31.6)

 35–39.9

41,564 (40.1)

176 (39.6)

90 (35.2)

84 (33.2)

  ≥ 40

7,726 (7.5)

37 (8.3)

14 (5.5)

14 (5.5)

Functional Status Prior to Surgery

0.865

 < 0.001

0.120

 Dependent

2,222 (2.1)

9 (2.0)

17 (6.7)

9 (3.6)

 Independent

101,181 (97.9)

434 (98.0)

237 (93.3)

243 (96.4)

Frailty

0.923

0.457

0.813

  < 2

102,223 (98.6)

438 (98.6)

251 (98.0)

249 (98.4)

  ≥ 2

1,457 (1.4)

6 (1.4)

5 (2.0)

4 (1.6)

ASA classification

 < 0.001

0.004

 < 0.001

  ≤ 2

54,372 (52.4)

165 (37.2)

111 (43.4)

83 (32.8)

  ≥ 3

49,308 (47.6)

279 (62.8)

145 (56.6)

170 (67.2)

Smoker

 < 0.001

 < 0.001

 < 0.001

 No

90,397 (87.2)

344 (77.5)

186 (72.7)

190 (75.1)

 Yes

13,283 (12.8)

100 (22.5)

70 (27.3)

63 (24.9)

Steroid use

0.829

0.392

0.564

 No

98,784 (95.3)

424 (95.5)

241 (94.1)

243 (96.0)

 Yes

4,896 (4.7)

20 (4.5)

15 (5.9)

10 (4.0)

Comorbidities

 HTN

60,670 (58.5)

269 (60.6)

0.385

138 (53.9)

0.144

144 (56.9)

0.606

 CHF

536 (0.5)

4 (0.9)

0.299

2 (0.8)

0.382

1 (0.4)

1.000

 Diabetes Mellitus

13,968 (13.5)

75 (16.9)

0.035

43 (16.8)

0.120

37 (14.6)

0.592

 COPD

4,634 (4.5)

25 (5.6)

0.238

12 (4.7)

0.879

14 (5.5)

0.363

 Bleeding Disorder

2,701 (2.6)

58 (13.1)

 < 0.001

34 (13.3)

 < 0.001

42 (16.6)

 < 0.001