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Table 1 Baseline characteristic of individuals in training set and validation set Mean ± SD/ [M(P25, P75)]/N(%)

From: Analysis of related factors for sarco-osteoporosis in middle-aged and elderly inpatients and development and validation of a nomogram

Variables

Training set (N = 270)

Validation set (N = 116)

P values

SOP

  

0.617b

 No

168(62.2%)

76(65.5%)

 

 Yes

102(37.8%)

40(34.5%)

 

Gender

  

0.730b

 Female

82(30.4%)

38(32.8%)

 

 Male

188(69.6%)

78(67.2%)

 

Education level

  

0.667b

 Below junior high school

196(72.6%)

81(69.8%)

 

 Junior high school and above

74(27.4%)

35(30.2%)

 

Residence

  

0.766b

 village

178(65.9%)

79(68.1%)

 

 urban

92(34.1%)

37(31.9%)

 

Falls

  

0.349b

 No

207(76.7%)

83(71.6%)

 

 Yes

63(23.3%)

33(28.4%)

 

Drinking

  

0.103b

 No

247(91.5%)

99(85.3%)

 

 Yes

23(8.5%)

17(14.7%)

 

Smoking

  

0.229b

 No

223(82.6%)

89(76.7%)

 

 Yes

47(17.4%)

27(23.3%)

 

Regular exercise

  

0.574b

 No

110(40.7%)

43(37.1%)

 

 Yes

160(59.3%)

73(62.9%)

 

Age(year)

66.0[59.0–72.0]

64.0[56.0-72.2]

0.076a

Number of comorbid diseases

1.0[0.0–1.0]

1.0[0.0–1.0]

0.948a

Height(cm)

154.5[149.0-160.0]

154.0[150.0-158.2]

0.754a

Weight(kg)

57.0[51.0–63.0]

58.0[52.0–65.0]

0.269a

BMI (kg/m^2)

24.0[22.0-26.2]

24.3[22.2–26.9]

0.348a

Ca(mmol/L)

2.2[2.1–2.3]

2.2[2.1–2.3]

0.146a

Blood glucose (mmol/L)

5.0[4.6–5.5]

5.0[4.5–5.5]

0.710a

TP(g/L)

62.7[59.5–66.5]

62.0[59.2–66.2]

0.169a

Albumin (g/L)

38.6(4.0)

37.9(3.8)

0.101a

Globulin (g/L)

224.3[183.2–262.0]

210.5[180.8-255.8]

0.177a

Prealbumin (mg/L)

24.5[22.0–27.0]

24.0[22.0–26.0]

0.614a

Creatinine(umol/L)

67.5[59.0–81.0]

67.0[59.8–79.0]

0.722a

GFR (ml(min1.73 m^2))

89.4[78.2-105.8]

92.2[80.8-103.8]

0.412a

ALT(U/L)

18.0[13.0-27.8]

18.0[13.8–26.5]

0.725a

AST(U/L)

23.5[19.0–30.0]

23.0[19.0-29.2]

0.679a

AST/ALT

1.3[1.0-1.7]

1.3[1.1–1.6]

0.521a

Bilirubin(umol/L)

10.6[8.2–14.3]

10.1[8.0-13.5]

0.391a

Hb(g/L)

125.5(17.0)

124.1(21.0)

0.516a

Neutrophile (10^9/L)

3.8[2.7–5.3]

3.6[2.9–4.6]

0.343a

Lymphocyte (10^9/L)

1.5[1.2–1.9]

1.7[1.2-2.0]

0.261a

Monocyte (10^9/L)

0.5[0.4–0.6]

0.5[0.4–0.6]

0.837a

Blood platelet (10^9/L)

206.5[164.0-249.0]

218.0[178.8-261.5]

0.088a

WBC (10^9/L)

6.2[4.9–7.8]

6.1[5.0-7.2]

0.650a

NLR

2.4[1.6–3.8]

2.1[1.5–3.3]

0.110a

PLR

129.0[97.8–177.0]

132.0[101.6-177.6]

0.608a

LMR

3.3[2.3–4.3]

3.6[2.4–4.8]

0.159a

AISI

236.0[131.8-443.5]

213.1[146.9-379.9]

0.617a

SIRI

1.1[0.7–2.2]

1.0[0.7–1.6]

0.199a

GNRI

102.7(9.0)

102.5(9.2)

0.859a

CC (cm)

32.3[31.0–34.0]

33.0[31.1–34.0]

0.186a

HGS (kg)

19.5[16.0-24.6]

20.1[15.9–25.4]

0.844a

SLMI (kg/m^2)

5.4[4.8-6.0]

5.6[5.2–6.1]

0.052a

Total body of Lean

55.2[49.8–60.0]

53.6[49.9–60.8]

0.904a

Total body of Fat

42.4[37.5–47.9]

43.8[35.9–47.7]

0.926a

FMI (kg/m^2)

10.4[8.4–12.3]

10.9[8.2–13.0]

0.557a

LMI (kg/m^2)

13.4[12.3–14.6]

13.6[12.6–14.7]

0.307a

BMR (kcal/Day)

1188.6[1108.1-1290.5]

1214.4[1114.0-1305.9]

0.122a

T-score

-3.2[-4.0;-2.5]

-2.9[-4.1;-2.2]

0.426a

Neck BMD(g/cm2)

0.6[0.6–0.7]

0.6[0.6–0.7]

0.189a

Total hip BMD(g/cm2)

0.7 ± 0.1

0.8 ± 0.1

0.040c

L1BMD(g/cm2)

0.6[0.5–0.7]

0.6[0.5–0.7]

0.498a

L2BMD(g/cm2)

0.6[0.5–0.7]

0.6[0.5–0.7]

0.239a

L3BMD(g/cm2)

0.7[0.6–0.8]

0.7[0.6–0.8]

0.617a

L4BMD(g/cm2)

0.7[0.6–0.8]

0.7[0.6–0.8]

0.671a

TLBMD

0.6[0.6–0.7]

0.7[0.5–0.8]

0.437a

  1. a: Mann-Whitney test; b: chi-square test; c: t test; SOP: sarco-osteoporosis; BMI: body mass index; AST: aspartate aminotransferase; GFR: glomerular filtration rate; ALT: alanine aminotransferase; NLR: neutrophil/lymphocyte ; PLR: platelet/lymphocyte; LMR: lymphocyte/monocyte; AISI: systemic inflammation aggregation index; SIRI: Systemic inflammatory response index; GNRI: geriatric nutritional risk index; SMMI: skeletal muscle mass index; FMI: fat mass index; LMI: lean mass index; BMR: basal metabolic rate; BMD: Bone mineral density