From: Associations between apolipoprotein B and bone mineral density: a population-based study
Apolipoprotein B (g/L) | Total | Q1 (≤ 0.70) | Q2 (0.71–0.87) | Q3 (0.88–1.04) | Q4 (≥ 1.05) | P-value |
---|---|---|---|---|---|---|
N = 4,258 | N = 1014 | N = 1100 | N = 1038 | N = 1106 | ||
Age (years) | 37.555 ± 12.312 | 32.878 ± 12.063 | 36.894 ± 12.192 | 40.022 ± 11.795 | 43.481 ± 10.158 | < 0.001 |
Sex, (%) | < 0.001 | |||||
Male | 52.020 | 47.561 | 49.789 | 51.799 | 61.100 | |
Female | 47.980 | 52.439 | 50.211 | 48.201 | 38.900 | |
Postmenopausal female | 11.165 | 8.542 | 10.419 | 12.498 | 11.716 | |
Premenopausal female | 36.815 | 43.897 | 39.792 | 35.703 | 27.184 | |
Race/Ethnicity (%) | 0.037 | |||||
Non-Hispanic White | 35.040 | 60.395 | 61.974 | 61.937 | 63.407 | |
Non-Hispanic Black | 21.536 | 14.152 | 11.881 | 9.941 | 9.652 | |
Mexican American | 15.101 | 8.944 | 10.126 | 11.198 | 11.692 | |
Other race/ethnicity | 28.323 | 16.509 | 16.020 | 16.925 | 15.249 | |
Education level (%) | < 0.001 | |||||
Less than high school | 15.176 | 12.818 | 14.757 | 14.933 | 18.195 | |
High school | 20.229 | 19.163 | 18.237 | 19.882 | 23.635 | |
More than high school | 64.595 | 68.019 | 67.006 | 65.185 | 58.170 | |
Moderate activities (%) | 0.048 | |||||
Yes | 43.776 | 49.854 | 47.320 | 45.134 | 44.159 | |
No | 56.224 | 50.146 | 52.680 | 54.866 | 55.841 | |
Smoked at least 100 cigarettes in life, n (%) | < 0.001 | |||||
Yes | 39.027 | 33.536 | 41.124 | 40.876 | 46.996 | |
No | 60.973 | 66.464 | 58.876 | 59.124 | 53.004 | |
Had at least 12 alcohol drinks in 1 year, n (%) | 0.010 | |||||
Yes | 73.258 | 76.667 | 79.409 | 78.790 | 81.705 | |
No | 16.742 | 23.333 | 20.591 | 21.210 | 18.295 | |
Diabetes, n (%) | 0.008 | |||||
Yes | 6.881 | 8.531 | 5.194 | 5.670 | 7.776 | |
No | 93.119 | 91.469 | 93.010 | 92.708 | 89.805 | |
Take prescription for cholesterol, (%) | 0.019 | |||||
Yes | 8.196 | 6.410 | 7.818 | 8.285 | 10.127 | |
No | 91.804 | 93.590 | 92.182 | 91.715 | 89.873 | |
Arthritis, n (%) | < 0.001 | |||||
Yes | 13.434 | 9.758 | 13.920 | 15.647 | 18.281 | |
No | 86.564 | 90.242 | 86.080 | 84.353 | 81.719 | |
Body mass index (kg/m2) | 28.761 ± 7.102 | 26.508 ± 6.762 | 28.541 ± 6.989 | 29.683 ± 6.805 | 30.695 ± 6.670 | < 0.001 |
Income to poverty ratio | 2.409 ± 1.662 | 2.6766 ± 1.6927 | 2.8033 ± 1.6928 | 2.9478 ± 1.6961 | 3.1525 ± 1.7327 | < 0.001 |
ALT (U/L) | 26.133 ± 19.656 | 21.376 ± 14.146 | 25.851 ± 21.278 | 27.169 ± 18.666 | 30.586 ± 18.620 | < 0.001 |
AST (U/L) | 25.700 ± 24.285 | 24.043 ± 24.677 | 25.962 ± 25.753 | 25.357 ± 14.509 | 27.010 ± 14.964 | 0.010 |
ALP (U/L) | 66.030 ± 22.041 | 61.745 ± 21.678 | 63.438 ± 20.193 | 65.566 ± 19.744 | 69.127 ± 27.203 | < 0.001 |
Total calcium (mg/dL) | 9.353 ± 0.329 | 9.325 ± 0.312 | 9.338 ± 0.326 | 9.341 ± 0.336 | 9.390 ± 0.332 | < 0.001 |
Serum phosphorus (mg/dL) | 3.729 ± 0.558 | 3.767 ± 0.561 | 3.722 ± 0.563 | 3.683 ± 0.539 | 3.638 ± 0.519 | < 0.001 |
Globulin (g/dL) | 2.868 ± 0.432 | 2.717 ± 0.410 | 2.785 ± 0.423 | 2.792 ± 0.404 | 2.831 ± 0.409 | < 0.001 |
Lumbar BMD (g/cm2) | 1.031 ± 0.150 | 1.057 ± 0.151 | 1.038 ± 0.152 | 1.021 ± 0.147 | 1.252 ± 0.160 | < 0.001 |
Total femur BMD (g/cm2) | 0.977 ± 0.141 | 0.981 ± 0.153 | 0.981 ± 0.153 | 0.962 ± 0.143 | 0.994 ± 0.124 | 0.027 |
Femoral neck BMD (g/cm2) | 0.814 ± 0.138 | 0.813 ± 0.152 | 0.825 ± 0.152 | 0.804 ± 0.139 | 0.816 ± 0.120 | 0.502 |