Fig. 2

Nomogram (The risk of musculoskeletal pain in OP patients receiving zoledronic acid injection for the first time was predicted by calculating the total score of the six parameters. NSAIDs: “Yes” means that NSAIDs are used before injection therapy, and the score is 0. “No” means that NSAIDs have not been used before injection therapy, and the score is 42 points. Age: “≥80years” means that the participant is 80 years of age or older and has a score of 0. “70–80 years” means the participant is 70–80 years old and scores 10 points. “60–70 years” means participants are 60–70 years old and score 30 points. “≤60 years” means that the participant is 60 years old or less, and the score is 54 points. Serum 25-hydroxyvitamin D: “≥30ng/ml” represents a Serum 25-hydroxyvitamin D level higher than 30ng/ml before injection. Score 0 points; “< 30ng/ml” means that the participant had less than 30ng/ml of Serum 25-hydroxyvitamin D before the injection and scored 100 points. Prior Vitamin D intake: “Yes” means that participants took Vitamin D intake before injection and scored 0 points. “No” means that participants did not take vitamin D supplementation before injection therapy and scored 52 points. BMI: “Yes” means the participant has a BMI of less than 24 kg/m2 and a score of 45; “No” means that the participant has a BMI greater than 24 kg/m2 and a score of 0.)