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Table 2 Symptom burden, fatigue, sleep quality and perceived social support in patients with and without MSK discomfort in HD patients

From: Symptom burden, fatigue, sleep quality and perceived social support in hemodialysis patients with musculoskeletal discomfort: a single center experience from Egypt

Variablea

Total

(n = 94)

median (min–max)

Without MSK discomfort

n = 26

median (min–max)

With MSK discomfort

n = 68

median (min–max)

Measure of effect

P

Modified (ESAS)

 Pain

4 (0–10)

0 (0–8)

4.5 (0–10)

0.388

 < 0.001*

 Fatigue

3 (0–9)

1 (0–6)

4 (0–9)

0.273

0.010*

 Nausea

0 (0–10)

0 (0–7)

1 (0–10)

0.168

0.114

 Depressed

3 (0–8)

0 (0–7)

4 (0–8)

0.259

0.015*

 Anxiety

3 (0–10)

0 (0–7)

4 (0–10)

0.315

0.003*

 Drowsiness

3 (0–10)

0 (0–7)

4 (0–8)

0.259

0.014*

 Shortness of breath

2 (0–9)

0 (0–7)

3 (0–9)

0.167

0.114

 Best appetite

4 (0–10)

3 (0–9)

5 (0–10)

0.173

0.103

 Best sleep

5 (0–10)

4 (0–9)

5 (0–10)

0.094

0.377

 Best feeling or wellbeing

4 (0–10)

4 (0–10)

4 (0–10)

0.151

0.153

Multidimensional Fatigue Inventory

 General fatigue

10 (6–16)

10 (7–13)

10 (6–16)

0.069

0.603

 Physical fatigue

11 (4–20)

12 (6–15)

11 (4–20)

0.046

0.706

 Reduced activity

10 (4–20)

9 (6–12)

11 (4–20)

0.298

0.020*

 Reduced motivation

10 (4–18)

9 (5–12)

10 (4–18)

0.238

0.083

 Mental fatigue

9 (3–16)

8 (5–13)

10 (3–16)

0.164

0.237

Pittsburgh Sleep Quality Index

 Subjective sleep quality

1 (0–3)

1 (0–3)

1 (0–3)

0.249

0.020*

 Sleep latency

2 (0–3)

2 (0–3)

2 (0–3)

0.083

0.438

 Sleep duration

2 (0–3)

2 (0–3)

2 (0–3)

0.080

0.436

 Habitual sleep efficiency

1 (0–3)

1 (0–3)

1 (0–3)

0.048

0.640

 Sleep disturbances

1 (0–3)

1 (0–2)

1 (0–3)

0.177

0.086

 Use of sleep medications

0 (0–3)

0 (0–3)

0 (0–3)

0.167

0.116

 Daytime dysfunction

1 (0–3)

0 (0–3)

1 (0–3)

0.229

0.031*

 Global PSQI score

7 (2–18)

6 (2–14)

8 (2–18)

-0.081

0.036*

Multidimensional Scale of Perceived Social Support (MSPSS)

 Significant Other Subscale

7 (1–7)

7 (1.5–7)

7 (1–7)

-0.034

0.753

 Family Subscale

6.75 (1.5–7)

6.75 (1.5–7)

6.5 (2.25–7)

-0.166

0.122

 Friends Subscale

4.5 (1–7)

5.5 (1–7)

4.13 (1–7)

-0.188

0.079

 MPSS Total Scale

5.58 (1.33–7)

6.25 (1.33–7)

5.54 (1.75–7)

-0.234

0.029*

  1. MSK musculoskeletal, PSQI Pittsburgh Sleep Quality Index, ESAS Edmonton Symptom Assessment System
  2. *p < 0.05
  3. aMann-Whitney test was used