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Table 3 Results of the repeated measures ANOVA models for SF-36 global score and each subscale – FAS population

From: Oral supplementation with fish cartilage hydrolysate in an adult population suffering from knee pain and function discomfort: results from an innovative approach combining an exploratory clinical study and an ex vivo clinical investigation

Variable

Baseline (n = 32)

After 1 month (n = 28)

After 3 months (n = 26)

P-value

Global score [mean ± SD]

61.05 ± 16.09

66.30 ± 13.93

66.99 ± 16.34

0.0024

Physical functioning [mean ± SD]

56.72 ± 21.43

58.21 ± 20.69

65.77 ± 23.52

0.0009

Role limitations due to physical health [mean ± SD]

52.34 ± 39.84

76.79 ± 31.13

75.96 ± 36.39

0.0027

Role limitation due to emotional problems [median (Q1-Q3)]

100.00 (66.67–100.00)

100.00 (66.67–100.00)

100.00 (33.33–100.00)

0.9406*

Energy/fatigue [mean ± SD]

55.78 ± 14.49

64.29 ± 15.01

55.96 ± 18.55

0.0030

Emotional well-being [mean ± SD]

65.25 ± 19.71

67.71 ± 17.52

62.77 ± 19.49

0.1660

Social functioning [median (Q1-Q3)]

75.00 (56.25–93.75)

81.25 (62.50–100.00)

75.00 (62.50–100.00)

0.5302*

Pain [mean ± SD]

50.86 ± 19.21

61.61 ± 15.96

64.90 ± 23.37

< 0.0001

General health [mean ± SD]

67.50 ± 12.95

64.82 ± 12.87

71.54 ± 11.47

0.0223

  1. * Friedman’s test p-value