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Table 2 Results of the repeated measures ANOVA models for KOOS global score and each subscale, and mean difference and effect size between baseline and 3 months of follow-up – FAS population

From: Oral supplementation with fish cartilage hydrolysate in an adult population suffering from knee pain and function discomfort: results from an innovative approach combining an exploratory clinical study and an ex vivo clinical investigation

Variable

Baseline (n = 32)

After 1 month (n = 28)

After 3 months (n = 26)

P-value

Mean difference (n = 26)

Effect size

Global score [mean ± SD]

45.24 ± 14.93

57.56 ± 19.09

63.76 ± 20.76

< 0.0001

19.31 ± 16.14

1.20

Pain* [mean ± SD]

48.26 ± 16.32

61.11 ± 19.74

70.09 ± 19.44

< 0.0001

22.44 ± 17.91

1.25

Symptom [mean ± SD]

55.58 ± 20.48

68.37 ± 20.01

73.76 ± 21.26

< 0.0001

18.54 ± 20.40

0.91

Activity of daily living [mean ± SD]

54.37 ± 16.96

65.23 ± 20.97

72.23 ± 20.83

< 0.0001

18.21 ± 13.24

1.38

Sport and recreation function [mean ± SD]

25.63 ± 16.40

40.18 ± 25.00

43.85 ± 28.86

< 0.0001

18.85 ± 22.46

0.84

Quality of life* [mean ± SD]

42.38 ± 19.10

52.90 ± 20.94

58.89 ± 24.95

< 0.0001

18.51 ± 20.35

0.91

  1. *log-transformed variable