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Fig. 7 | BMC Musculoskeletal Disorders

Fig. 7

From: Oral supplementation with fish cartilage hydrolysate in an adult population suffering from knee pain and function discomfort: results from an innovative approach combining an exploratory clinical study and an ex vivo clinical investigation

Fig. 7

Primary human chondrocytes were incubated in the presence or absence of rhIL-1b (1ng/ml) in combination with either human naive serum (H-NAIVE) or human serum enriched with metabolites derived from FCH ingestion (H-FCH). PGE2 (A) and Nitric Oxide (B) production. Measures were performed in quadruplicates per condition/volunteer (n = 10 volunteers). Values are presented as mean ± SEM. The differences were considered statistically significant at p < 0.05 with * for p < 0.05; *** for p < 0.001; **** for p < 0.0001

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