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Table 3 Joint arthropathies, FISH and treatment modalities in case and control groups

From: Osteoporosis and associated risk factors in patients with severe hemophilia A: a case-control study from China

Parameters

Normal group(n = 31)

Osteoporosis group(n = 22)

P

FISHa

16.00(4.53)

11.82(3.23)

.001

Joint countb

2(1/6)

4(2/7)

<.001

Hip

   

Normal

16(30.19%)

0(0.00%)

<.001

Unilateral

10(18.87%)

7(13.21%)

 

Bilateral

5(9.43%)

15(28.30%)

 

Knee

   

Normal

2(3.77%)

0(0.00%)

<.001

Unilateral

22(41.51%)

4(7.55%)

 

Bilateral

7(13.21%)

18(33.96%)

 

Ankle

   

Normal

20(37.74%)

11(20.75%)

.229

Unilateral

10(18.87%)

9(16.98%)

 

Bilateral

1(1.89%)

2(3.77%)

 

Shoulder

  

Normal

26(49.06%)

18(33.96%)

.419

Unilateral

5(9.43%)

2(3.77%)

 

Bilateral

0(0.00%)

2(3.77%)

 

Elbow

   

Normal

25(47.17%)

14(26.42%)

.118

Unilateral

6(11.32%)

7(13.21%)

 

Bilateral

0(0.00%)

1(1.89%)

 

Treatment

  

.563

On-demand Treatment

1(1.89%)

2(3.77%)

 

Long-term regular

tertiary prophylaxis

30(56.60%)

20(37.74%)

 

Age at start(years)a

35.15(5.76)

36.42(9.61)

.585

Therapy time(month)a

29.33(18.29)

33.50(18.71)

.438

Prophylactic dose(IU/Kg)a

20.69(9.55)

25.77(10.09)

.078

  1. aMean(SD)
  2. bMedian (IQR)