Skip to main content

Table 5 GRADE scores for each predictive variable

From: Preoperative predictors for return to physical activity following anterior cruciate ligament reconstruction (ACLR): a systematic review

Summary of Results

GRADE Assessment

Factors that may decrease the quality

Factors that may increase the quality

Quality

Preoperative Predictive Factor

Number of Participants (studies)

Study Limitations

Inconsistency

Indirectness

Imprecision

Moderate/large effect size

Dose effect

Physical activity rating scale

1) Tegner

2) Marx

403 (4)

High/moderate risk of bias using QUIPS

Inconsistencyb

Indirectnessc

No imprecision

No moderate or large effect size

No exposure-response gradient

\(\oplus\)◯◯◯

Very low

Knee specific patient reported outcome measure

1) Lysholm

2) IKDC

3) ‘Knee function’ (measured using two questions from the IKDC)

4) Noyes

164 (2)

High risk of bias using QUIPS

Inconsistencyb

Indirectnessc

Imprecisione

No moderate or large effect size

No exposure-response gradient

\(\oplus\)◯◯◯

Very low

Passive knee range of motion

64 (1)

High risk of bias using QUIPS

Inconsistencya

Indirectnessd

Imprecisione

No moderate or large effect size

No exposure-response gradient

\(\oplus\)◯◯◯

Very low

Thigh muscle torque

64 (1)

High risk of bias using QUIPS

Inconsistencya

Indirectnessd

Imprecisione

No moderate or large effect size

No exposure-response gradient

\(\oplus\)◯◯◯

Very low

Anterior knee pain

64 (1)

High risk of bias using QUIPS

Inconsistencya

Indirectnessd

Imprecisione

No moderate or large effect size

No exposure-response gradient

\(\oplus\)◯◯◯

Very low

Weight

179 (2)

High/moderate risk of bias using QUIPS

Inconsistencyb

Indirectnessc

Imprecisionef

No moderate or large effect size

No exposure-response gradient

\(\oplus\)◯◯◯

Very low

BMI

278 (2)

High risk of bias using QUIPS

Inconsistencyb

Indirectnessc

Imprecisiong

No moderate or large effect size

No exposure-response gradient

\(\oplus\)◯◯◯

Very low

Graft type

64 (1)

High risk of bias using QUIPS

Inconsistencya

Indirectnessd

Imprecisione

No moderate or large effect size

No exposure-response gradient

\(\oplus\)◯◯◯

Very low

Psychovitality

100 (1)

High risk of bias using QUIPS

Inconsistencya

No indirectness

Imprecisione

No moderate or large effect size

No exposure-response gradient

\(\oplus\)◯◯◯

Very low

Estimation of time (number of months) to achieve postoperative outcomes markers

65 (1)

Moderate risk of bias using QUIPS

Inconsistencya

No indirectness

Imprecisione

No moderate or large effect size

No exposure-response gradient

\(\oplus\)◯◯◯

Very low

Goal to return to preinjury level

65 (1)

Moderate risk of bias using QUIPS

Inconsistencya

No indirectness

Imprecisione

No moderate or large effect size

No exposure-response gradient

\(\oplus\)◯◯◯

Very low

Estimation of ability to return to preinjury level

65 (1)

Moderate risk of bias using QUIPS

Inconsistencya

No indirectness

Imprecisione

No moderate or large effect size

No exposure-response gradient

\(\oplus\)◯◯◯

Very low

Knee Self-Efficacy Scale (K-SES)

38 (1)

High risk of bias using QUIPS

Inconsistencya

No indirectness

Imprecisione

No moderate or large effect size

No exposure-response gradient

\(\oplus\)◯◯◯

Very low

Time to surgery

119 (2)

High/moderate risk of bias using QUIPS

Inconsistencyb

Indirectnessc

Imprecisiong

No moderate or large effect size

No exposure-response gradient

\(\oplus\)◯◯◯

Very low

Smoking status

55 (1)

Moderate risk of bias using QUIPS

Inconsistencya

Indirectnessd

Imprecisione

No moderate or large effect size

No exposure-response gradient

\(\oplus\)◯◯◯

Very low

  1. aOnly single trial available
  2. bEstimates of the predictive factors association with the outcome vary in direction and/or no confidence intervals available to assess overlap
  3. cVariety in the outcome measures used and time-points at which they were assessed
  4. dThe final sample only represents a subset of the population of interest
  5. eSmall sample size < 400 – single study
  6. fVariety in time-points at which the preoperative factor is assessed
  7. gSmall sample size < 400 – multiple studies