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Fig. 3 | BMC Musculoskeletal Disorders

Fig. 3

From: Astragalus polysaccharide ameliorates steroid-induced osteonecrosis of the femoral head by regulating miR-200b-3p-mediated Wnt/β-catenin signaling pathway via inhibiting SP1 expression

Fig. 3

SP1 suppressed the effect of APS on DEX-induced MLO-Y4 cell damage. APS-treated SONFH cell model was transfected with oe-SP1 (APS + oe-SP1 group) or control vector (APS + oe-NC group). (A) Immunofluorescence detection of LC3 expression. (B) Western blot determination of autophagy-related proteins. (C) Flow cytometry analyzed cell apoptosis. (D) Western blot evaluated apoptosis-related proteins. Results expressed as mean ± SD. *P < 0.05, **P < 0.01

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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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