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Fig. 2 | BMC Musculoskeletal Disorders

Fig. 2

From: Astragalus polysaccharide ameliorates steroid-induced osteonecrosis of the femoral head by regulating miR-200b-3p-mediated Wnt/β-catenin signaling pathway via inhibiting SP1 expression

Fig. 2

APS inhibited SP1 expression in DEX-treated MLO-Y4 cells. (A) mRNA microarray analysis of differentially expressed genes between control group and SONFH group. (B) RT-qPCR detected the content of differentially expressed genes. (C) RT-qPCR analyzed expression changes of each gene in SONFH cell model with/without APS treatment. (D, E) RT-qPCR and Western blot detection of SP1 level in APS-treated SONFH cell model with oe-SP1 (APS + oe-SP1 group) or oe-NC (APS + oe-NC group). Data are the means ± SD for three independent experiments. **P < 0.01

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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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