Association between serum uric acid levels and bone mineral density in patients with osteoporosis: a cross-sectional study

Table 4 Threshold analyses examining the relationship between SUA levels and BMD

	Model 3^a
BMI	< 24 kg/m² β (95% CI) P-value	24–28 kg/m² β (95% CI) P-value	≥ 28 kg/m² β (95% CI) P-value	Total
Model A^b					P-interaction: 0.673
One line effect	0.0239 (0.0118, 0.0361) 0.0001	0.0291 (0.0116, 0.0466) 0.0012	0.0500 (0.0251, 0.0749) 0.0001		0.0286 (0.0193, 0.0378) < 0.0001
Model B^c					P-interaction: 0.499
Serum uric acid turning point (K), per 100 μmol/L	2.96	1.91	4.98		2.94
< K	0.0438 (0.0217, 0.0658) 0.0001	-0.0129 (-0.1679, 0.1422) 0.8709	0.0437 (0.0124, 0.0750) 0.0073		0.0413 (0.0229, 0.0598) < 0.0001
> K	0.0029 (-0.0200, 0.0259) 0.8024	0.0309 (0.0122, 0.0495) 0.0013	0.0827 (-0.0180, 0.1834) 0.1106		0.0187 (0.0032, 0.0342) 0.0184
Slope 2 – Slope 1	-0.0408 (-0.0788, -0.0029) 0.0352	0.0437 (-0.1167, 0.2041) 0.5936	0.0390 (-0.0775, 0.1555) 0.5130		-0.0226 (-0.0511, 0.0058) 0.1186
BMD value at K, g/cm²	0.7621 (0.7453, 0.7788)	0.7491 (0.7241, 0.7741)	0.8663 (0.8097, 0.9229)		0.7748 (0.7621, 0.7875)
LRT test^d	0.034	0.590	0.498		0.117

Abbreviations: SUA serum uric acid, BMD bone mineral density, CI confidence interval, BMI body mass index, 25(OH)D 25-hydroxy vitamin D, BUN blood urea nitrogen, LRT logarithmic likelihood ratio test
^aAdjusted for age, gender, 25(OH)D levels and BUN
^bLinear analysis, P-value < 0.05 indicates a linear relationship
^cNon-linear analysis
^dP-value < 0.05 means Model B is significantly different from Model A, which indicates a non-linear relationship

ISSN: 1471-2474