Table 1 Patient characteristics based on SUA quartiles

N

1249

311

311

313

314

BMD, g/cm²

0.76 ± 0.14

0.71 ± 0.12

0.75 ± 0.13

0.78 ± 0.14

0.80 ± 0.15

 < 0.001

 < 0.001

Age, y

67.94 ± 9.61

68.28 ± 8.69

66.90 ± 9.61

67.74 ± 9.31

68.83 ± 10.66

0.076

0.053

Platelet count, × 10⁹/L

185.12 ± 61.04

185.08 ± 64.99

191.84 ± 58.52

181.59 ± 53.16

181.98 ± 66.29

0.133

0.045

Neutrophil count, × 10⁹/L

4.47 ± 2.35

4.38 ± 2.12

4.51 ± 2.42

4.35 ± 2.39

4.66 ± 2.44

0.355

0.206

Lymphocyte count, × 10⁹/L

1.41 ± 0.56

1.27 ± 0.50

1.40 ± 0.54

1.48 ± 0.59

1.47 ± 0.58

 < 0.001

 < 0.001

Monocyte count, × 10⁹/L

0.41 ± 0.19

0.40 ± 0.17

0.41 ± 0.18

0.40 ± 0.20

0.43 ± 0.20

0.168

0.257

Albumin, g/L

40.26 ± 4.75

39.76 ± 4.37

40.61 ± 4.65

40.58 ± 4.69

40.07 ± 5.21

0.070

0.013

Hemoglobin, g/L

124.20 ± 16.72

121.98 ± 18.46

125.07 ± 14.24

125.26 ± 14.39

124.47 ± 19.04

0.055

0.065

Calcium, mmol/L

2.27 ± 0.18

2.24 ± 0.22

2.27 ± 0.15

2.28 ± 0.13

2.28 ± 0.20

0.012

 < 0.001

ALT, U/L

21.14 ± 13.59

18.85 ± 10.84

20.56 ± 13.62

21.04 ± 11.96

24.09 ± 16.72

 < 0.001

 < 0.001

AST, U/L

23.82 ± 10.68

21.99 ± 8.27

23.37 ± 9.82

23.93 ± 9.93

25.96 ± 13.61

 < 0.001

0.002

Cr, μmol/L

61.39 ± 24.98

54.87 ± 19.63

55.32 ± 12.87

60.61 ± 18.73

74.66 ± 36.56

 < 0.001

 < 0.001

CRP, mg/L

1.66 ± 4.60

1.35 ± 3.10

1.75 ± 3.56

1.51 ± 3.49

2.05 ± 7.10

0.760

0.762

BUN, mmol/L

6.24 ± 1.82

5.76 ± 1.45

5.83 ± 1.45

6.33 ± 1.60

7.03 ± 2.33

 < 0.001

 < 0.001

Glucose, mmol/L

6.06 ± 1.95

6.32 ± 2.14

6.12 ± 2.01

5.88 ± 1.62

5.92 ± 1.96

0.019

0.041

Total cholesterol, mmol/L

4.58 ± 1.01

4.52 ± 1.04

4.71 ± 1.05

4.54 ± 0.95

4.56 ± 0.99

0.166

0.110

Triglyceride, mmol/L

1.38 ± 0.93

1.22 ± 1.12

1.30 ± 0.72

1.37 ± 0.82

1.60 ± 0.98

 < 0.001

 < 0.001

High-density lipoprotein, mmol/L

1.46 ± 0.33

1.50 ± 0.33

1.52 ± 0.33

1.45 ± 0.35

1.40 ± 0.30

 < 0.001

 < 0.001

Low-density lipoprotein, mmol/L

2.74 ± 0.81

2.63 ± 0.85

2.80 ± 0.79

2.71 ± 0.78

2.82 ± 0.80

0.056

0.040

Apolipoprotein A, g/L

1.38 ± 0.27

1.38 ± 0.27

1.42 ± 0.29

1.36 ± 0.27

1.35 ± 0.26

0.038

0.030

Apolipoprotein B, g/L

0.90 ± 0.24

0.87 ± 0.25

0.92 ± 0.24

0.89 ± 0.23

0.91 ± 0.23

0.085

0.076

Homocysteine, μmol/L

13.12 ± 6.80

11.34 ± 4.91

12.50 ± 7.03

12.88 ± 5.46

15.44 ± 8.39

 < 0.001

 < 0.001

25(OH)D levels, ng/mL

20.81 ± 8.19

18.52 ± 7.41

21.25 ± 8.20

20.89 ± 7.81

22.59 ± 8.79

 < 0.001

 < 0.001

Gender, N (%)

 < 0.001

-

 Male

233 (18.65%)

25 (8.04%)

46 (14.79%)

64 (20.45%)

98 (31.21%)

 Female

1016 (81.35%)

286 (91.96%)

265 (85.21%)

249 (79.55%)

216 (68.79%)

BMI categorical, N (%)

 < 0.001

-

  < 24 kg/m²

778 (62.29%)

223 (71.70%)

206 (66.24%)

186 (59.42%)

163 (51.91%)

  24–28 kg/m²

358 (28.66%)

75 (24.12%)

85 (27.33%)

100 (31.95%)

98 (31.21%)

  ≥ 28 kg/m²

113 (9.05%)

13 (4.18%)

20 (6.43%)

27 (8.63%)

53 (16.88%)

CCI score categorical, N (%)

0.197

-

 0

879 (70.38%)

234 (75.24%)

224 (72.03%)

209 (66.77%)

212 (67.52%)

 1–2

194 (15.53%)

47 (15.11%)

39 (12.54%)

53 (16.93%)

55 (17.52%)

 3–4

107 (8.57%)

17 (5.47%)

28 (9.00%)

34 (10.86%)

28 (8.92%)

  ≥ 5

69 (5.52%)

13 (4.18%)

20 (6.43%)

17 (5.43%)

19 (6.05%)

Calcitonin usage, N (%)

0.017

-

 No

973 (77.90%)

223 (71.70%)

243 (78.14%)

254 (81.15%)

253 (80.57%)

 Yes

276 (22.10%)

88 (28.30%)

68 (21.86%)

59 (18.85%)

61 (19.43%)

Surgery, N (%)

 < 0.001

-

 No

636 (50.92%)

119 (38.26%)

162 (52.09%)

179 (57.19%)

176 (56.05%)

 Yes

613 (49.08%)

192 (61.74%)

149 (47.91%)

134 (42.81%)

138 (43.95%)

Primary diagnosis, N (%)

 < 0.001

-

OP without fractures

771 (61.73%)

151 (48.55%)

193 (62.06%)

213 (68.05%)

214 (68.15%)

OPF

478 (38.27%)

160 (51.45%)

118 (37.94%)

100 (31.95%)

100 (31.85%)