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Table 2 Function Outcomes

From: Surgical interventions for symptomatic knee osteoarthritis: a network meta-analysis of randomized control trials

Study, Year

Interventions

Prosthesis

Function Outcomes

Results

1. Wu 2022

TKA

Sigma PFC cemented TKA (DePuy, Warsaw, IN, USA)

HSS, WOMAC, KSS, VAS, OKS, ROM, FJS

3 years: ND (VAS and KSS function); SD (HSS, ROM WOMAC, OKS, FJS)

 

UKA

(1) Oxford phase 3 (Zimmer Biomet, Warsaw, IN, USA); (2) Link medial FB UKA (Link, Endo-model Sled, Germany).

2. Knifsund 2021

TKA

Triathlon (Stryker, Mahwah, New Jersey, USA) cruciate-retaining device.

OKS, KOOS, 15D, KSS, ROM

2 years: ND (OKS, KOOS pain, KOOS function, KOOS quality of life and 15D); SD (KOOS symptoms, ROM)

 

UKA

Oxford phase 3 mobile-bearing device.

3. Beard 2019

TKA

(1) Low Contact Stress or PFC/Sigma (DePuy Orthopaedics Inc.); (2) Vanguard or NexGen® (Zimmer Biomet); (3) Triathlon® Knee System (Stryker, Mahwah, NJ, USA); (4) Genesis or Genesis (Smith & Nephew, Memphis, TN, USA); (5) ACS® (Implantcast, Buxtehude, Germany); (6) EUROS (Euros SAS, La Ciotat, France); (7) AllPoly (Zimmer Biomet); (8) Oxinium (Smith & Nephew)

OKS, KSS, UCLA, HAAS, EQ-5D-3 L, EQ-5D-VAS

5 years: ND (OKS, EQ-5D-3 L, HAAS, UCLA, KSS); SD (EQ-5D-VAS)

 

UKA

1. Oxford® Partial Knee (Zimmer Biomet, Warsaw, IN, USA) ; 2. Zimmer or Vanguard® (Zimmer Biomet); 3. M/G® Unicompartmental Knee System (Zimmer Biomet); 4. Uniglide™ (Corin Group, Cirencester, UK); 5. AMC (Corin Group); 6. DePuy (DePuy Orthopaedics Inc., Warsaw, IN, USA); 7. Mathys (Mathys Ltd, Bettlach, Switzerland); 8. Medacta (Medacta International, Castel San Pietro, Switzerland); 9. Sigma (DePuy Orthopaedics Inc.).

4. Kulshrestha 2017

TKA

A cemented, posterior-stabilized implant (None Details)

KOS-ADLS, HAAS, OKS, EQ-5D-VAS

2 years: ND

 

UKA

A fixed bearing design (None Details)

5. Murray 2014

TKA

NA

OKS, EQ-5D, SF-12 PCS, SF-12 MCS

10 years: ND

 

UKA

NA

6. Sun 2012

TKA

AGC, Biomet

KSS, ROM, VAS

4.3 years: ND

 

UKA

Oxford Biomet, Warsaw, IN, USA

7. Costa 2011

TKA

Scorpio1, cruciate retaining system (Stryker Orthopaedics,

Mahwah, NJ)

KSS-functional or clinical

5 years: ND

 

UKA

(1) EIUS1 fixed bearing system (Stryker Orthopaedics, Mahwah, NJ); (2) Zimmer1 Unicompartmental High-Flex Knee System (Zimmer Inc., Warsaw, IN).

8. Newman 2009

TKA

Posterior-cruciate-preserving Kinematic Modular TKR (Howmedica, Rutherford, New Jersey)

BKS, ROM

15 years: ND

 

UKA

St Georg Sled UKR (Waldemar Link, Hamburg, Germany)

9. Weale 1999

TKA

Posterior-cruciate-preserving Kinematic Modular TKR (Howmedica, Rutherford, New Jersey)

5 years: ND (BKS), SD (ROM)

 

UKA

St Georg Sled UKR (Waldemar Link, Hamburg, Germany)

10. Newman 1998

TKA

Posterior-cruciate-preserving Kinematic Modular TKR (Howmedica, Rutherford, New Jersey)

 

UKA

St Georg Sled UKR (Waldemar Link, Hamburg, Germany)

11. Börjesson 2005

UKA

Brigham prosthesis

BOA, Borg CR-10, ROM

5 years: ND

 

HTO

A Coventry closing wedge osteotomy

12. Stukenborg-Colsman 2001

UKA

Tübingen pattern, Aesculap®

KSS-functional or clinical, ROM

7–10 years: ND

 

HTO

A modified osteotomy of Coventry and Weber

13. weidenhielm 1992

UKA

Brigham prosthesis

BOA

1 year: ND

 

HTO

A closing wedge osteotomy of Coverntry

14. Goh 2020

TKA

DePuy Sigma®, Fixed Bearing Knee System, Warsaw, Indiana, United States

OKS, AKSS, SF-36 (PCS, MCS)

10 years: ND

 

BCA

DePuy Preservation™ Unicompartmental Knee, Warsaw, Indiana, United States and DePuy Sigma® High Performance Partial Knee, Warsaw, Indiana, United States

15. Yeo 2015

TKA

DePuy Sigma®, Fixed Bearing Knee System, Warsaw, Indiana, United States

OKS, AKSS, SF-36 (PCS, MCS)

5 years: ND

 

BCA

DePuy Preservation™ Unicompartmental Knee, Warsaw, Indiana, United States and DePuy Sigma® High Performance Partial Knee, Warsaw, Indiana, United States

16. Schrednitzki 2020

TKA

Innex System (Zimmer Biomet, Warsaw, IN).

KSS-functional or clinical, OKS, UCLA, FJS, TUGT, ROM

5 years: ND (KSS, OKS, UCLA, FJS, TUGT); SD (ROM)

 

BCA

Sigma HP Partial Knee System (DePuy, Warsaw, IN)

17. Engh 2014

TKA

Genesis II TKA components (Smith & Nephew, Andover, MA)

KSS, OKS, FAT

2 years: ND

 

BCA

Journey Deuce (Smith & Nephew, Andover, MA)

18. Blyth 2021

TKA

NexGen LPS implant (Zimmer, USA)

VAS, OKS, KSS, FJS, EQ-5D-3 L, UCLA, HADS, ROM, TUGT, SCT

1 year: ND

 

BIU

Medial and lateral Restoris MCK (MultiCompartmental Knee)

19. Jansen 2021

TKA

Genesis II posterior stabilised system (Smith & Nephew, Warsaw, Indiana)

WOMAC, KOOS, VAS, EQ-5D-3 L, SF-36 (PCS and MCS)

2 years: KJD VS TKA ND (WOMAC), SD (KOSS, VAS, EQ-5D, SF-36); KJD VS HTO ND (WOMAC, KOSS, VAS, EQ-5D, SF-36)

 

HTO

Opening-wedge osteotomy (TomoFix medial high tibial plates and screws (DePuy Synthes, Switzerland) or Synthes locking

compression plate (LCP) system (DePuy Synthes, Switzerland))

 

KJD

Triax proof-of-concept external distraction device (Stryker, Kalamazoo, Michigan)

20. van der Woude 2017 A

HTO

Opening-wedge osteotomy (TomoFix medial high tibial plates and screws (DePuy Synthes, Switzerland) or Synthes locking

compression plate (LCP) system (DePuy Synthes, Switzerland))

WOMAC, KOOS, VAS, EQ-5D-3 L, SF-36 (PCS and MCS)

1 year: ND (WOMAC, KOSS, VAS, EQ-5D, SF-36 MCS), SD (VAS, SF-36 PCS)

 

KJD

Triax proof-of-concept external distraction device (Stryker, Kalamazoo, Michigan)

21. van der Woude 2017 B

TKA

Genesis II posterior stabilised system (Smith & Nephew, Warsaw, Indiana)

WOMAC, KOOS, VAS, EQ-5D-3 L, SF-36 (PCS and MCS)

1 year: ND (WOMAC, KOSS, VAS, EQ-5D, SF-36), SD (ROM)

 

KJD

Triax proof-of-concept external distraction device (Stryker, Kalamazoo, Michigan)

  1. TKA: Total Knee Arthroplasty, UKA: Unicompartmental Knee Arthroplasty, HTO: High Tibial Osteotomy, BCA: Bicompartmental Knee Arthroplasty, BIU: Bi-unicompartmental Knee Arthroplasty, KJD: Knee Joint Distraction, HSS: Hospital for Special Surgery Knee Score, WOMAC: The Western Ontario and McMaster Universities Index, KSS: Knee Society Score, VAS: Visual Analog Scale, OKS: Oxford Knee Score, ROM: Range of motion, FJS: The Forgotten Joint Score, KOOS: Knee injury and Osteoarthritis Score, 15D: 15-Dmensional Instrument, EQ-5D-3 L: EuroQol EQ-5D-3 L, UCLA: University of California, Los Angeles Activity score, HAAS: High Activity Arthroplasty Score, KOS-ADLS: Knee Outcome Survey-Activities of Daily Living Scale, SF-12: Short Form Questionnaire-12 Items, BKS: Bristol Knee Score, BOA: British Orthopaedic Association Score, SF-36: Short Form 36, TUGT: Timed-Up-and-Go Test. FAT: Functional Assessment Test, HADS: Hospital Anxiety and Depression Scale, SCT: stair climbing test, NA: Not Applicable, ND: No Significant Difference, SD: Significant Difference