Fig. 1

Study flowchart. *Obvious organ dysfunction or organ failure, including failing heart with level IV of cardiac function, kidney failure with estimated glomerular filtration rate (eGFR) below 60 mL/min, liver failure with aminopherase above 1,600 U/L, TBil (total bilirubin) above 171 μmol/L, with/without hepatic encephalopathy, coagulation defects with PTA (prothrombin activity) below 40%. ^#No reconsultation data from medical record; reconsulted but no diagnosis given; all data lost