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Table 3 Pathological manifestations of patients in this study

From: Anti-signal recognition particle positive necrotizing myopathy-sjogren’s syndrome overlap syndrome: a descriptive study on clinical and myopathology features

 

Anti-SRP IMNM-SS (n = 6)

Anti-SRP IMNM (n = 24)

P value

CD4 (cell count > 5)

Total

6(100)

13(54.2)

0.013

Necrosis

4(66.7)

4(16.7)

0.023

Endomysial

5(83.3)

7(29.2)

0.013

Perimysial

0

0

0.108

Perivascular

0

0

0.219

CD8 (cell count > 5)

Total

2(33.3)

6(25)

0.614

Necrosis

3(50)

1(4.2)

0.355

Endomysial

0

1(4.2)

0.573

Perimysial

0

0

0.421

Perivascular

0

0

0.268

CD20 (cell count > 5)

Total

3(50)

1(4.2)

0.176

Necrosis

2(33.3)

0

0.123

Endomysial

0

0

0.7

Perimysial

0

0

0.387

Perivascular

0

0

 > 0.9999

CD68 (cell count > 5)

Total

6(100)

12(50)

0.046

Necrosis

4(66.7)

8(33.3)

0.176

Endomysial

2(33.3)

2(8.3)

0.016

Perimysial

0

0

0.295

Perivascular

0

0

0.614

MHC(Grading Scales)

Sarcolemmal/Sarcoplasmic staining

5(83.3)

18(75)

0.387

MAC(Grading Scales)

Sarcolemmal

5(83.3)

4(16.7)

0.013

Sarcoplasm

3(50)

9(37.5)

 > 0.9999

Capillary

3(50)

2(8.3)

0.176

  1. Data presented as n (%). P values comparing two groups are from Mann–Whitney U test